Chronic testosterone propionate supplement could activated the Nrf2-ARE pathway in the brain and ameliorated the behaviors of aged rats

Behavioural Brain Research

Volumn 252, Issue , 2013, Pages 388-395

  Zhang, Guo Liang ^a   Wang, Wei ^a,b   Kang, Yun Xiao ^a   Xue, Yan ^a   Yang, Huan ^a   Zhou, Chen Ming ^a   Shi, Ge Ming ^a  

^a HEBEI MEDICAL UNIVERSITY   (China)

^b First Hospital of Handan   (China)

Author keywords

Aged rat; Heme oxygenase 1; NAD(P)H: quinone oxidoreductase 1; Nrf2 ARE; Oxidative stress; Testosterone propionate

Indexed keywords

HEME OXYGENASE 1; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (QUINONE); TESTOSTERONE PROPIONATE; TRANSCRIPTION FACTOR NRF2;

AGING; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIOXIDANT RESPONSIVE ELEMENT; ARTICLE; BRAIN REGION; CELL DEATH; CHRONIC DRUG ADMINISTRATION; CONTROLLED STUDY; DRUG MECHANISM; LOCOMOTION; MALE; MUSCLE STRENGTH; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PUTAMEN; RAT; SIGNAL TRANSDUCTION; SUBSTANTIA NIGRA; UPREGULATION;

AGED RAT; HEME OXYGENASE-1; NAD(P)H: QUINONE OXIDOREDUCTASE-1; NRF2-ARE; OXIDATIVE STRESS; TESTOSTERONE PROPIONATE;

AGE FACTORS; AGING; ANDROGENS; ANIMALS; ANTIOXIDANT RESPONSE ELEMENTS; ANTIOXIDANTS; BRAIN; GLUTATHIONE; HEME OXYGENASE-1; MALE; MALONDIALDEHYDE; NAD(P)H DEHYDROGENASE (QUINONE); NF-E2-RELATED FACTOR 2; OXIDATIVE STRESS; POSTURAL BALANCE; RATS; RATS, WISTAR; RNA, MESSENGER; SIGNAL TRANSDUCTION; SPECTROPHOTOMETRY; STATISTICS, NONPARAMETRIC; TESTOSTERONE PROPIONATE;

EID: 84880148379     PISSN: 01664328     EISSN: 18727549     Source Type: Journal    
DOI: 10.1016/j.bbr.2013.05.063     Document Type: Article

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