CRISPR-Cas encoding of a digital movie into the genomes of a population of living bacteria

Nature

Volumn 547, Issue 7663, 2017, Pages 345-349

  Shipman, Seth L ^a,b,c   Nivala, Jeff ^a,c   Macklis, Jeffrey D ^b   Church, George M ^a,c  

^a HARVARD MEDICAL SCHOOL   (United States)

^b Harvard University   (United States)

^c HARVARD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

NUCLEOTIDE; OLIGONUCLEOTIDE; INTEGRASE;

BACTERIUM; CELLS AND CELL COMPONENTS; DNA; GENE; GENETIC ANALYSIS; IMMUNE SYSTEM; IMMUNITY; LABORATORY METHOD;

ACCURACY; ARTICLE; BACTERIAL GENOME; BACTERIUM CULTURE; CELL VIABILITY; CRISPR CAS SYSTEM; CRYSTAL STRUCTURE; DNA BASE COMPOSITION; ELECTROPORATION; HIGH THROUGHPUT SEQUENCING; NONHUMAN; PRIORITY JOURNAL; BIOTECHNOLOGY; CYTOLOGY; ESCHERICHIA COLI; GENE EDITING; GENETICS; METABOLISM; MICROBIAL VIABILITY; MOVIE; NUCLEOTIDE SEQUENCE; PROCEDURES;

BACTERIA (MICROORGANISMS);

BASE SEQUENCE; BIOTECHNOLOGY; CRISPR-CAS SYSTEMS; ESCHERICHIA COLI; GENE EDITING; GENOME, BACTERIAL; INTEGRASES; MICROBIAL VIABILITY; MOTION PICTURES; OLIGONUCLEOTIDES;

EID: 85025473790     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature23017     Document Type: Article

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