Structure-guided redesign of d-fructose-6-phosphate aldolase from E. coli: Remarkable activity and selectivity towards acceptor substrates by two-point mutation

Chemical Communications

Volumn 47, Issue 20, 2011, Pages 5762-5764

  Gutierrez, Mariana ^a   Parella, Teodor ^b   Joglar, Jesús ^a   Bujons, Jordi ^a   Clapés, Pere ^a  

^a INSTITUTE OF ADVANCED CHEMISTRY OF CATALONIA IQAC CSIC   (Spain)

^b UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; ALDEHYDE DERIVATIVE; DEXTRO FRUCTOSE 6 PHOSPHATE ALDOLASE; FRUCTOSE BISPHOSPHATE ALDOLASE; GLYCINE; SERINE; UNCLASSIFIED DRUG;

AMINO ACID SUBSTITUTION; ARTICLE; BINDING SITE; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENZYME ACTIVITY; ENZYME SUBSTRATE; ENZYME SYNTHESIS; ESCHERICHIA COLI; GENE CONSTRUCT; GENE MUTATION; MUTANT; NONHUMAN; SITE DIRECTED MUTAGENESIS; STEREOCHEMISTRY; WILD TYPE;

EID: 79955572384     PISSN: 13597345     EISSN: 1364548X     Source Type: Journal    
DOI: 10.1039/c1cc11069a     Document Type: Article

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