메뉴 건너뛰기




Volumn 7, Issue 8, 2012, Pages

Mutations in Escherichia coli aceE and ribB genes allow survival of strains defective in the first step of the isoprenoid biosynthesis pathway

Author keywords

[No Author keywords available]

Indexed keywords

1 DEOXY DEXTRO XYLULOSE 5 PHOSPHATE REDUCTOISOMERASE; 1 DEOXY DEXTRO XYLULOSE 5 PHOSPHATE SYNTHASE; 2 METHYL DEXTRO ERYTHRITOL 4 PHOSPHATE; ERYTHRITOL; ISOPRENOID; OXIDOREDUCTASE; UNCLASSIFIED DRUG;

EID: 84865155372     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0043775     Document Type: Article
Times cited : (25)

References (42)
  • 1
    • 27744577599 scopus 로고    scopus 로고
    • Biogenesis, molecular regulation and function of plant isoprenoids
    • Bouvier F, Rahier A, Camara B, (2005) Biogenesis, molecular regulation and function of plant isoprenoids. Prog Lipid Res 44: 357-429.
    • (2005) Prog Lipid Res , vol.44 , pp. 357-429
    • Bouvier, F.1    Rahier, A.2    Camara, B.3
  • 2
    • 0030846307 scopus 로고    scopus 로고
    • Creating isoprenoid diversity
    • Sacchettini JC, Poulter CD, (1997) Creating isoprenoid diversity. Science 277: 1788-1789.
    • (1997) Science , vol.277 , pp. 1788-1789
    • Sacchettini, J.C.1    Poulter, C.D.2
  • 3
    • 84856585187 scopus 로고    scopus 로고
    • A raison d'etre for two distinct pathways in the early steps of plant isoprenoid biosynthesis?
    • Hemmerlin A, Harwood JL, Bach TJ, (2012) A raison d'etre for two distinct pathways in the early steps of plant isoprenoid biosynthesis? Prog Lipid Res 51: 95-148.
    • (2012) Prog Lipid Res , vol.51 , pp. 95-148
    • Hemmerlin, A.1    Harwood, J.L.2    Bach, T.J.3
  • 4
    • 0031474261 scopus 로고    scopus 로고
    • Two independent biochemical pathways for isopentenyl diphosphate and isoprenoid biosynthesis in higher plants
    • Lichtenthaler HK, Rohmer M, Schwender J, (1997) Two independent biochemical pathways for isopentenyl diphosphate and isoprenoid biosynthesis in higher plants. Physiologia plantarum 101: 643-652.
    • (1997) Physiologia Plantarum , vol.101 , pp. 643-652
    • Lichtenthaler, H.K.1    Rohmer, M.2    Schwender, J.3
  • 5
    • 0036851226 scopus 로고    scopus 로고
    • Elucidation of the methylerythritol phosphate pathway for isoprenoid biosynthesis in bacteria and plastids. A metabolic milestone achieved through genomics
    • Rodríguez-Concepción M, Boronat A, (2002) Elucidation of the methylerythritol phosphate pathway for isoprenoid biosynthesis in bacteria and plastids. A metabolic milestone achieved through genomics. Plant Physiol 130: 1079-1089.
    • (2002) Plant Physiol , vol.130 , pp. 1079-1089
    • Rodríguez-Concepción, M.1    Boronat, A.2
  • 6
    • 23844526860 scopus 로고    scopus 로고
    • Isoprenoid biosynthetic pathways as anti-infective drug targets
    • Rohdich F, Bacher A, Eisenreich W, (2005) Isoprenoid biosynthetic pathways as anti-infective drug targets. Biochem Soc Trans 33: 785-791.
    • (2005) Biochem Soc Trans , vol.33 , pp. 785-791
    • Rohdich, F.1    Bacher, A.2    Eisenreich, W.3
  • 7
    • 3042782938 scopus 로고    scopus 로고
    • The MEP pathway: a new target for the development of herbicides, antibiotics and antimalarial drugs
    • Rodriguez-Concepcion M, (2004) The MEP pathway: a new target for the development of herbicides, antibiotics and antimalarial drugs. Curr Pharm Des 10: 2391-2400.
    • (2004) Curr Pharm Des , vol.10 , pp. 2391-2400
    • Rodriguez-Concepcion, M.1
  • 9
    • 0032478189 scopus 로고    scopus 로고
    • Cloning and characterization of a gene from Escherichia coli encoding a transketolase-like enzyme that catalyzes the synthesis of D-1-deoxyxylulose 5-phosphate, a common precursor for isoprenoid, thiamin, and pyridoxol biosynthesis
    • Lois LM, Campos N, Putra SR, Danielsen K, Rohmer M, et al. (1998) Cloning and characterization of a gene from Escherichia coli encoding a transketolase-like enzyme that catalyzes the synthesis of D-1-deoxyxylulose 5-phosphate, a common precursor for isoprenoid, thiamin, and pyridoxol biosynthesis. Proc Natl Acad Sci USA 95: 2105-2110.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 2105-2110
    • Lois, L.M.1    Campos, N.2    Putra, S.R.3    Danielsen, K.4    Rohmer, M.5
  • 10
    • 0030696041 scopus 로고    scopus 로고
    • Identification of a thiamin-dependent synthase in Escherichia coli required for the formation of the 1-deoxy-D-xylulose 5-phosphate precursor to isoprenoids, thiamin, and pyridoxol
    • Sprenger GA, Schorken U, Wiegert T, Grolle S, de Graaf AA, et al. (1997) Identification of a thiamin-dependent synthase in Escherichia coli required for the formation of the 1-deoxy-D-xylulose 5-phosphate precursor to isoprenoids, thiamin, and pyridoxol. Proc Natl Acad Sci USA 94: 12857-12862.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 12857-12862
    • Sprenger, G.A.1    Schorken, U.2    Wiegert, T.3    Grolle, S.4    de Graaf, A.A.5
  • 11
    • 0343614184 scopus 로고    scopus 로고
    • A family of transketolases that directs isoprenoid biosynthesis via a mevalonate-independent pathway
    • Lange BM, Wildung MR, McCaskill D, Croteau R, (1998) A family of transketolases that directs isoprenoid biosynthesis via a mevalonate-independent pathway. Proc Natl Acad Sci USA 95: 2100-2104.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 2100-2104
    • Lange, B.M.1    Wildung, M.R.2    McCaskill, D.3    Croteau, R.4
  • 12
    • 0032543467 scopus 로고    scopus 로고
    • Direct formation of 2-C-methyl-D-erythritol 4-phosphate from 1-deoxy-D-xylulose 5-phosphate by 1-deoxy-D-xylulose 5-phosphate reductoisomerase, a new enzyme in the non-mevalonate pathway to isopentenyl diphosphate
    • Kuzuyama T, Takahashi S, Watanabe H, Seto H, (1998) Direct formation of 2-C-methyl-D-erythritol 4-phosphate from 1-deoxy-D-xylulose 5-phosphate by 1-deoxy-D-xylulose 5-phosphate reductoisomerase, a new enzyme in the non-mevalonate pathway to isopentenyl diphosphate. Tetrahedron Letters 39: 4509-4512.
    • (1998) Tetrahedron Letters , vol.39 , pp. 4509-4512
    • Kuzuyama, T.1    Takahashi, S.2    Watanabe, H.3    Seto, H.4
  • 13
    • 0032544054 scopus 로고    scopus 로고
    • A 1-deoxy-D-xylulose 5-phosphate reductoisomerase catalyzing the formation of 2-C-methyl-D-erythritol 4-phosphate in an alternative non-mevalonate pathway for terpenoid biosynthesis
    • Takahashi S, Kuzuyama T, Watanabe H, Seto H, (1998) A 1-deoxy-D-xylulose 5-phosphate reductoisomerase catalyzing the formation of 2-C-methyl-D-erythritol 4-phosphate in an alternative non-mevalonate pathway for terpenoid biosynthesis. Proc Natl Acad Sci USA 95: 9879-9884.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 9879-9884
    • Takahashi, S.1    Kuzuyama, T.2    Watanabe, H.3    Seto, H.4
  • 14
    • 77956282463 scopus 로고    scopus 로고
    • A new family of enzymes catalyzing the first committed step of the methylerythritol 4-phosphate (MEP) pathway for isoprenoid biosynthesis in bacteria
    • Sangari FJ, Perez-Gil J, Carretero-Paulet L, Garcia-Lobo JM, Rodriguez-Concepcion M, (2010) A new family of enzymes catalyzing the first committed step of the methylerythritol 4-phosphate (MEP) pathway for isoprenoid biosynthesis in bacteria. Proc Natl Acad Sci U S A 107: 14081-14086.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 14081-14086
    • Sangari, F.J.1    Perez-Gil, J.2    Carretero-Paulet, L.3    Garcia-Lobo, J.M.4    Rodriguez-Concepcion, M.5
  • 15
    • 34547609909 scopus 로고    scopus 로고
    • The non-mevalonate pathway of isoprenoid precursor biosynthesis
    • Hunter WN, (2007) The non-mevalonate pathway of isoprenoid precursor biosynthesis. J Biol Chem 282: 21573-21577.
    • (2007) J Biol Chem , vol.282 , pp. 21573-21577
    • Hunter, W.N.1
  • 16
    • 0038043258 scopus 로고    scopus 로고
    • Structural basis of fosmidomycin action revealed by the complex with 2-C-methyl-D-erythritol 4-phosphate synthase (IspC). Implications for the catalytic mechanism and anti-malaria drug development
    • Steinbacher S, Kaiser J, Eisenreich W, Huber R, Bacher A, et al. (2003) Structural basis of fosmidomycin action revealed by the complex with 2-C-methyl-D-erythritol 4-phosphate synthase (IspC). Implications for the catalytic mechanism and anti-malaria drug development. J Biol Chem 278: 18401-18407.
    • (2003) J Biol Chem , vol.278 , pp. 18401-18407
    • Steinbacher, S.1    Kaiser, J.2    Eisenreich, W.3    Huber, R.4    Bacher, A.5
  • 17
    • 84860852496 scopus 로고    scopus 로고
    • Crystal structure of the Brucella abortus deoxyxylulose 5-phosphate reductoisomerase-like (DRL) enzyme involved in isoprenoid biosynthesis
    • C B
    • Perez-Gil J, Calisto BM, C B, Kurz T, Fita I, et al. (2012) Crystal structure of the Brucella abortus deoxyxylulose 5-phosphate reductoisomerase-like (DRL) enzyme involved in isoprenoid biosynthesis. J Biol Chem 287: 15803-15809.
    • (2012) J Biol Chem , vol.287 , pp. 15803-15809
    • Perez-Gil, J.1    Calisto, B.M.2    Kurz, T.3    Fita, I.4
  • 18
    • 0032558613 scopus 로고    scopus 로고
    • Fosmidomycin, a specific inhibitor of 1-deoxy-D-xylulose 5-phosphate reductoisomerase in the nonmevalonate pathway for terpenoid biosynthesis
    • Kuzuyama T, Shimizu T, Takahashi S, Seto H, (1998) Fosmidomycin, a specific inhibitor of 1-deoxy-D-xylulose 5-phosphate reductoisomerase in the nonmevalonate pathway for terpenoid biosynthesis. Tetrahedron Letters 39: 7913-7916.
    • (1998) Tetrahedron Letters , vol.39 , pp. 7913-7916
    • Kuzuyama, T.1    Shimizu, T.2    Takahashi, S.3    Seto, H.4
  • 19
    • 0032439587 scopus 로고    scopus 로고
    • Inhibition of the non-mevalonate 1-deoxy-D-xylulose-5-phosphate pathway of plant isoprenoid biosynthesis by fosmidomycin
    • Zeidler J, Schwender J, Muller C, Wiesner J, Weidemeyer C, et al. (1998) Inhibition of the non-mevalonate 1-deoxy-D-xylulose-5-phosphate pathway of plant isoprenoid biosynthesis by fosmidomycin. Z Naturfosch 53c: 980-986.
    • (1998) Z Naturfosch , vol.53 c , pp. 980-986
    • Zeidler, J.1    Schwender, J.2    Muller, C.3    Wiesner, J.4    Weidemeyer, C.5
  • 20
    • 2842613801 scopus 로고    scopus 로고
    • Fosmidomycin resistance in adenylate cyclase deficient (cya) mutants of Escherichia coli
    • Sakamoto Y, Furukawa S, Ogihara H, Yamasaki M, (2003) Fosmidomycin resistance in adenylate cyclase deficient (cya) mutants of Escherichia coli. Biosci Biotechnol Biochem 67: 2030-2033.
    • (2003) Biosci Biotechnol Biochem , vol.67 , pp. 2030-2033
    • Sakamoto, Y.1    Furukawa, S.2    Ogihara, H.3    Yamasaki, M.4
  • 21
    • 42549100536 scopus 로고    scopus 로고
    • Dxr is essential in Mycobacterium tuberculosis and fosmidomycin resistance is due to a lack of uptake
    • Brown AC, Parish T, (2008) Dxr is essential in Mycobacterium tuberculosis and fosmidomycin resistance is due to a lack of uptake. BMC Microbiol 8: 78.
    • (2008) BMC Microbiol , vol.8 , pp. 78
    • Brown, A.C.1    Parish, T.2
  • 22
    • 0030579174 scopus 로고    scopus 로고
    • Cloning of a gene from Escherichia coli that confers resistance to fosmidomycin as a consequence of amplification
    • Fujisaki S, Ohnuma S, Horiuchi T, Takahashi I, Tsukui S, et al. (1996) Cloning of a gene from Escherichia coli that confers resistance to fosmidomycin as a consequence of amplification. Gene 175: 83-87.
    • (1996) Gene , vol.175 , pp. 83-87
    • Fujisaki, S.1    Ohnuma, S.2    Horiuchi, T.3    Takahashi, I.4    Tsukui, S.5
  • 23
    • 0035154356 scopus 로고    scopus 로고
    • Escherichia coli engineered to synthesize isopentenyl diphosphate and dimethylallyl diphosphate from mevalonate: a novel system for the genetic analysis of the 2-C-methyl-D-erythritol 4-phosphate pathway for isoprenoid biosynthesis
    • Campos N, Rodriguez-Concepcion M, Sauret-Gueto S, Gallego F, Lois LM, et al. (2001) Escherichia coli engineered to synthesize isopentenyl diphosphate and dimethylallyl diphosphate from mevalonate: a novel system for the genetic analysis of the 2-C-methyl-D-erythritol 4-phosphate pathway for isoprenoid biosynthesis. Biochem J 353: 59-67.
    • (2001) Biochem J , vol.353 , pp. 59-67
    • Campos, N.1    Rodriguez-Concepcion, M.2    Sauret-Gueto, S.3    Gallego, F.4    Lois, L.M.5
  • 24
    • 0035857397 scopus 로고    scopus 로고
    • New approach to multiply deuterated isoprenoids using triply engineered Escherichia coli and its potential as a tool for mechanistic enzymology
    • Kakinuma K, Dekishima Y, Matsushima Y, Eguchi T, Misawa N, et al. (2001) New approach to multiply deuterated isoprenoids using triply engineered Escherichia coli and its potential as a tool for mechanistic enzymology. J Am Chem Soc 123: 1238-1239.
    • (2001) J Am Chem Soc , vol.123 , pp. 1238-1239
    • Kakinuma, K.1    Dekishima, Y.2    Matsushima, Y.3    Eguchi, T.4    Misawa, N.5
  • 25
    • 31444432723 scopus 로고    scopus 로고
    • A mutant pyruvate dehydrogenase E1 subunit allows survival of Escherichia coli strains defective in 1-deoxy-D-xylulose 5-phosphate synthase
    • Sauret-Güeto S, Uros EM, Ibanez E, Boronat A, Rodriguez-Concepcion M, (2006) A mutant pyruvate dehydrogenase E1 subunit allows survival of Escherichia coli strains defective in 1-deoxy-D-xylulose 5-phosphate synthase. FEBS Lett 580: 736-740.
    • (2006) FEBS Lett , vol.580 , pp. 736-740
    • Sauret-Güeto, S.1    Uros, E.M.2    Ibanez, E.3    Boronat, A.4    Rodriguez-Concepcion, M.5
  • 26
    • 0034685844 scopus 로고    scopus 로고
    • Genetic evidence of branching in the isoprenoid pathway for the production of isopentenyl diphosphate and dimethylallyl diphosphate in Escherichia coli
    • Rodríguez-Concepción M, Campos N, Maria Lois L, Maldonado C, Hoeffler JF, et al. (2000) Genetic evidence of branching in the isoprenoid pathway for the production of isopentenyl diphosphate and dimethylallyl diphosphate in Escherichia coli. FEBS Lett 473: 328-332.
    • (2000) FEBS Lett , vol.473 , pp. 328-332
    • Rodríguez-Concepción, M.1    Campos, N.2    Maria Lois, L.3    Maldonado, C.4    Hoeffler, J.F.5
  • 27
    • 0024553747 scopus 로고
    • Rapid extraction of bacterial genomic DNA with guanidium thiocyanate
    • Pitcher DG, Saunders NA, Owen RJ, (1989) Rapid extraction of bacterial genomic DNA with guanidium thiocyanate. Lett Appl Microbiol 8: 151-156.
    • (1989) Lett Appl Microbiol , vol.8 , pp. 151-156
    • Pitcher, D.G.1    Saunders, N.A.2    Owen, R.J.3
  • 28
    • 0031420392 scopus 로고    scopus 로고
    • Biosynthesis of riboflavin: 3,4-dihydroxy-2-butanone-4-phosphate synthase
    • Richter G, Krieger C, Volk R, Kis K, Ritz H, et al. (1997) Biosynthesis of riboflavin: 3,4-dihydroxy-2-butanone-4-phosphate synthase. Methods Enzymol 280: 374-382.
    • (1997) Methods Enzymol , vol.280 , pp. 374-382
    • Richter, G.1    Krieger, C.2    Volk, R.3    Kis, K.4    Ritz, H.5
  • 30
    • 48149106189 scopus 로고    scopus 로고
    • Metabolic engineering of microorganisms for isoprenoid production
    • Kirby J, Keasling JD, (2008) Metabolic engineering of microorganisms for isoprenoid production. Nat Prod Rep 25: 656-661.
    • (2008) Nat Prod Rep , vol.25 , pp. 656-661
    • Kirby, J.1    Keasling, J.D.2
  • 31
    • 0034700150 scopus 로고    scopus 로고
    • Isoprenoid biosynthesis: the evolution of two ancient and distinct pathways across genomes
    • Lange BM, Rujan T, Martin W, Croteau R, (2000) Isoprenoid biosynthesis: the evolution of two ancient and distinct pathways across genomes. Proc Natl Acad Sci U S A 97: 13172-13177.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 13172-13177
    • Lange, B.M.1    Rujan, T.2    Martin, W.3    Croteau, R.4
  • 32
    • 0033859551 scopus 로고    scopus 로고
    • The role of lateral gene transfer in the evolution of isoprenoid biosynthesis pathways
    • Boucher Y, Doolittle WF, (2000) The role of lateral gene transfer in the evolution of isoprenoid biosynthesis pathways. Mol Microbiol 37: 703-716.
    • (2000) Mol Microbiol , vol.37 , pp. 703-716
    • Boucher, Y.1    Doolittle, W.F.2
  • 33
    • 3042767995 scopus 로고    scopus 로고
    • Biochemical characterization of Bacillus subtilis type II isopentenyl diphosphate isomerase, and phylogenetic distribution of isoprenoid biosynthesis pathways
    • Laupitz R, Hecht S, Amslinger S, Zepeck F, Kaiser J, et al. (2004) Biochemical characterization of Bacillus subtilis type II isopentenyl diphosphate isomerase, and phylogenetic distribution of isoprenoid biosynthesis pathways. Eur J Biochem 271: 2658-2669.
    • (2004) Eur J Biochem , vol.271 , pp. 2658-2669
    • Laupitz, R.1    Hecht, S.2    Amslinger, S.3    Zepeck, F.4    Kaiser, J.5
  • 34
    • 0037394552 scopus 로고    scopus 로고
    • Diversity of the biosynthesis of the isoprene units
    • Kuzuyama T, Seto H, (2003) Diversity of the biosynthesis of the isoprene units. Nat Prod Rep 20: 171-183.
    • (2003) Nat Prod Rep , vol.20 , pp. 171-183
    • Kuzuyama, T.1    Seto, H.2
  • 35
    • 3042732189 scopus 로고    scopus 로고
    • Inactivation of sll1556 in Synechocystis strain PCC 6803 impairs isoprenoid biosynthesis from pentose phosphate cycle substrates in vitro
    • Poliquin K, Ershov YV, Cunningham FX Jr, Woreta TT, Gantt RR, et al. (2004) Inactivation of sll1556 in Synechocystis strain PCC 6803 impairs isoprenoid biosynthesis from pentose phosphate cycle substrates in vitro. J Bacteriol 186: 4685-4693.
    • (2004) J Bacteriol , vol.186 , pp. 4685-4693
    • Poliquin, K.1    Ershov, Y.V.2    Cunningham Jr., F.X.3    Woreta, T.T.4    Gantt, R.R.5
  • 36
    • 0036724815 scopus 로고    scopus 로고
    • Isoprenoid biosynthesis in Synechocystis sp. strain PCC6803 is stimulated by compounds of the pentose phosphate cycle but not by pyruvate or deoxyxylulose-5-phosphate
    • Ershov YV, Gantt RR, Cunningham Jr FX Jr, Gantt E, (2002) Isoprenoid biosynthesis in Synechocystis sp. strain PCC6803 is stimulated by compounds of the pentose phosphate cycle but not by pyruvate or deoxyxylulose-5-phosphate. J Bacteriol 184: 5045-5051.
    • (2002) J Bacteriol , vol.184 , pp. 5045-5051
    • Ershov, Y.V.1    Gantt, R.R.2    Cunningham Jr., F.X.3    Gantt, E.4
  • 37
    • 0035970116 scopus 로고    scopus 로고
    • An unusual isopentenyl diphosphate isomerase found in the mevalonate pathway gene cluster from Streptomyces sp. strain CL190
    • Kaneda K, Kuzuyama T, Takagi M, Hayakawa Y, Seto H, (2001) An unusual isopentenyl diphosphate isomerase found in the mevalonate pathway gene cluster from Streptomyces sp. strain CL190. Proc Natl Acad Sci U S A 98: 932-937.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 932-937
    • Kaneda, K.1    Kuzuyama, T.2    Takagi, M.3    Hayakawa, Y.4    Seto, H.5
  • 38
    • 0032537476 scopus 로고    scopus 로고
    • Thiamin-dependent enzymes as catalysts in chemoenzymatic syntheses
    • Schoerken U, Sprenger GA, (1998) Thiamin-dependent enzymes as catalysts in chemoenzymatic syntheses. Biochim Biophys Acta 1385(2): 229-243.
    • (1998) Biochim Biophys Acta , vol.1385 , Issue.2 , pp. 229-243
    • Schoerken, U.1    Sprenger, G.A.2
  • 39
    • 0000642166 scopus 로고
    • Formation of 1-deoxyketoses by pyruvate dehydrogenase and acetoin dehydrogenase
    • Yokota A, Sasajima KI, (1986) Formation of 1-deoxyketoses by pyruvate dehydrogenase and acetoin dehydrogenase. Agric Biol Chem 50: 2517-2524.
    • (1986) Agric Biol Chem , vol.50 , pp. 2517-2524
    • Yokota, A.1    Sasajima, K.I.2
  • 40
    • 0034832084 scopus 로고    scopus 로고
    • Phosphorylation of 1-deoxy-D-xylulose by D-xylulokinase of Escherichia coli
    • Wungsintaweekul J, Herz S, Hecht S, Eisenreich W, Feicht R, et al. (2001) Phosphorylation of 1-deoxy-D-xylulose by D-xylulokinase of Escherichia coli. Eur J Biochem 268: 310-316.
    • (2001) Eur J Biochem , vol.268 , pp. 310-316
    • Wungsintaweekul, J.1    Herz, S.2    Hecht, S.3    Eisenreich, W.4    Feicht, R.5
  • 42
    • 33745455746 scopus 로고    scopus 로고
    • Early steps in isoprenoid biosynthesis: Multilevel regulation of the supply of common precursors in plant cells
    • Rodríguez-Concepción M, (2006) Early steps in isoprenoid biosynthesis: Multilevel regulation of the supply of common precursors in plant cells. Phytochem Rev 5: 1-15.
    • (2006) Phytochem Rev , vol.5 , pp. 1-15
    • Rodríguez-Concepción, M.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.