-
1
-
-
69749101514
-
Osteosarcoma
-
Messerschmitt PJ, Garcia RM, Abdul-Karim FW, Greenfield EM, Getty PJ. Osteosarcoma. J Am Acad Orthop Surg 2009;17:515–27.
-
(2009)
J Am Acad Orthop Surg
, vol.17
, pp. 515-527
-
-
Messerschmitt, P.J.1
Garcia, R.M.2
Abdul-Karim, F.W.3
Greenfield, E.M.4
Getty, P.J.5
-
3
-
-
78650959663
-
Massive genomic rearrangement acquired in a single catastrophic event during cancer development
-
Stephens PJ, Greenman CD, Fu B, Yang F, Bignell GR, Mudie LJ, et al. Massive genomic rearrangement acquired in a single catastrophic event during cancer development. Cell 2011;144:27–40.
-
(2011)
Cell
, vol.144
, pp. 27-40
-
-
Stephens, P.J.1
Greenman, C.D.2
Fu, B.3
Yang, F.4
Bignell, G.R.5
Mudie, L.J.6
-
4
-
-
84899027159
-
Bone environment is essential for osteosarcoma development from transformed mesenchymal stem cells
-
Rubio R, Abarrategi A, Garcia-Castro J, Martinez-Cruzado L, Suarez C, Tornin J, et al. Bone environment is essential for osteosarcoma development from transformed mesenchymal stem cells. Stem Cells 2014;32: 1136–48.
-
(2014)
Stem Cells
, vol.32
, pp. 1136-1148
-
-
Rubio, R.1
Abarrategi, A.2
Garcia-Castro, J.3
Martinez-Cruzado, L.4
Suarez, C.5
Tornin, J.6
-
5
-
-
84937733083
-
Bone microenvironment signals in osteosarcoma development
-
Alfranca A, Martinez-Cruzado L, Tornin J, Abarrategi A, Amaral T, de Alava E, et al. Bone microenvironment signals in osteosarcoma development. Cell Mol Life Sci 2015;72:3097–113.
-
(2015)
Cell Mol Life Sci
, vol.72
, pp. 3097-3113
-
-
Alfranca, A.1
Martinez-Cruzado, L.2
Tornin, J.3
Abarrategi, A.4
Amaral, T.5
De Alava, E.6
-
6
-
-
77953669219
-
The epidemiology of osteosarcoma
-
Ottaviani G, Jaffe N. The epidemiology of osteosarcoma. Cancer Treat Res 2009;152:3–13.
-
(2009)
Cancer Treat Res
, vol.152
, pp. 3-13
-
-
Ottaviani, G.1
Jaffe, N.2
-
7
-
-
21244436009
-
Height as a risk factor for osteosarcoma
-
Longhi A, Pasini A, Cicognani A, Baronio F, Pellacani A, Baldini N, et al. Height as a risk factor for osteosarcoma. J Pediatr Hematol Oncol 2005;27:314–8.
-
(2005)
J Pediatr Hematol Oncol
, vol.27
, pp. 314-318
-
-
Longhi, A.1
Pasini, A.2
Cicognani, A.3
Baronio, F.4
Pellacani, A.5
Baldini, N.6
-
8
-
-
79952284127
-
Hallmarks of cancer: The next generation
-
Hanahan D, Weinberg RA. Hallmarks of cancer: the next generation. Cell 2011;646–74.
-
(2011)
Cell
, vol.646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
9
-
-
34948896045
-
Mesenchymal stem cells within tumour stroma promote breast cancer metastasis
-
Karnoub AE, Dash AB, Vo AP, Sullivan A, Brooks MW, Bell GW, et al. Mesenchymal stem cells within tumour stroma promote breast cancer metastasis. Nature 2007;449:557–63.
-
(2007)
Nature
, vol.449
, pp. 557-563
-
-
Karnoub, A.E.1
Dash, A.B.2
Vo, A.P.3
Sullivan, A.4
Brooks, M.W.5
Bell, G.W.6
-
10
-
-
84899011003
-
Recruited brain tumor-derived mesenchymal stem cells contribute to brain tumor progression
-
Behnan J, Isakson P, Joel M, Cilio C, Langmoen IA, Vik-Mo EO, et al. Recruited brain tumor-derived mesenchymal stem cells contribute to brain tumor progression. Stem Cells 2014;32:1110–23.
-
(2014)
Stem Cells
, vol.32
, pp. 1110-1123
-
-
Behnan, J.1
Isakson, P.2
Joel, M.3
Cilio, C.4
Langmoen, I.A.5
Vik-Mo, E.O.6
-
11
-
-
84871365780
-
Stroma-directed imatinib therapy impairs the tumor-promoting effect of bone marrow-derived mesenchymal stem cells in an orthotopic transplantation model of colon cancer
-
Shinagawa K, Kitadai Y, Tanaka M, Sumida T, Onoyama M, Ohnishi M, et al. Stroma-directed imatinib therapy impairs the tumor-promoting effect of bone marrow-derived mesenchymal stem cells in an orthotopic transplantation model of colon cancer. Int J Cancer 2012;132:813–23.
-
(2012)
Int J Cancer
, vol.132
, pp. 813-823
-
-
Shinagawa, K.1
Kitadai, Y.2
Tanaka, M.3
Sumida, T.4
Onoyama, M.5
Ohnishi, M.6
-
12
-
-
67349110806
-
Human mesenchymal stem cells (hmscs) target osteosarcoma and promote its growth and pulmonary metastasis
-
Xu W, Bian Z, Fan Q, Li G, Tang T. Human mesenchymal stem cells (hMSCs) target osteosarcoma and promote its growth and pulmonary metastasis. Cancer Lett 2009;281:32–41.
-
(2009)
Cancer Lett
, vol.281
, pp. 32-41
-
-
Xu, W.1
Bian, Z.2
Fan, Q.3
Li, G.4
Tang, T.5
-
14
-
-
84901489826
-
Infiltrating bone marrow mesenchymal stem cells increase prostate cancer stem cell population and metastatic ability via secreting cytokines to suppress androgen receptor signaling
-
Luo J, Ok Lee S, Liang L, Huang C-K, Li L, Wen S, et al. Infiltrating bone marrow mesenchymal stem cells increase prostate cancer stem cell population and metastatic ability via secreting cytokines to suppress androgen receptor signaling. Oncogene 2013;33:2768–78.
-
(2013)
Oncogene
, vol.33
, pp. 2768-2778
-
-
Luo, J.1
Ok Lee, S.2
Liang, L.3
Huang, C.-K.4
Li, L.5
Wen, S.6
-
15
-
-
84884204620
-
Mesenchymal stem cells promote growth and angiogenesis of tumors in mice
-
Huang W-H, Chang M-C, Tsai K-S, Hung M-C, Chen H-L, Hung S-C. Mesenchymal stem cells promote growth and angiogenesis of tumors in mice. Oncogene 2013;32:4343–54.
-
(2013)
Oncogene
, vol.32
, pp. 4343-4354
-
-
Huang, W.-H.1
Chang, M.-C.2
Tsai, K.-S.3
Hung, M.-C.4
Chen, H.-L.5
Hung, S.-C.6
-
16
-
-
84877724314
-
Recruitment of mesenchymal stem cells into prostate tumours promotes metastasis
-
Jung Y, Kim JK, Shiozawa Y, Wang J, Mishra A, Joseph J, et al. Recruitment of mesenchymal stem cells into prostate tumours promotes metastasis. Nat Commun 2013;4:1795.
-
(2013)
Nat Commun
, vol.4
, pp. 1795
-
-
Jung, Y.1
Kim, J.K.2
Shiozawa, Y.3
Wang, J.4
Mishra, A.5
Joseph, J.6
-
17
-
-
40049112564
-
Ceramide triggers budding of exosome vesicles into multivesicular endosomes
-
Trajkovic K, Hsu C, Chiantia S, Rajendran L, Wenzel D, Wieland F, et al. Ceramide triggers budding of exosome vesicles into multivesicular endosomes. Science 2008;319:1244–7.
-
(2008)
Science
, vol.319
, pp. 1244-1247
-
-
Trajkovic, K.1
Hsu, C.2
Chiantia, S.3
Rajendran, L.4
Wenzel, D.5
Wieland, F.6
-
18
-
-
57049103401
-
Glioblastoma microvesicles transport rna and proteins that promote tumour growth and provide diagnostic biomarkers
-
Skog J, Wurdinger T, van Rijn S, Meijer DH, Gainche L, Sena-Esteves M, etal. Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers. Nat Cell Biol 2008; 10:1470–6.
-
(2008)
Nat Cell Biol
, vol.10
, pp. 1470-1476
-
-
Skog, J.1
Wurdinger, T.2
Van Rijn, S.3
Meijer, D.H.4
Gainche, L.5
Sena-Esteves, M.6
-
19
-
-
84959386845
-
Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes
-
Kowal J, Arras G, Colombo M, Jouve M, Morath JP, Primdal-Bengtson B, et al. Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes. Proc Natl Acad Sci U S A 2016;113:E968–77.
-
(2016)
Proc Natl Acad Sci U S A
, vol.113
, pp. E968-E977
-
-
Kowal, J.1
Arras, G.2
Colombo, M.3
Jouve, M.4
Morath, J.P.5
Primdal-Bengtson, B.6
-
20
-
-
84862007577
-
Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through Met
-
Peinado H, Alečković M, Lavotshkin S, Matei I, Costa-Silva B, Moreno-Bueno G, et al. Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET. Nat Med 2012; 18:883–91.
-
(2012)
Nat Med
, vol.18
, pp. 883-891
-
-
Peinado, H.1
Alečković, M.2
Lavotshkin, S.3
Matei, I.4
Costa-Silva, B.5
Moreno-Bueno, G.6
-
21
-
-
84930225521
-
In vivo imaging reveals extracellular vesicle-mediated phenocopying of metastatic behavior
-
Zomer A, Maynard C, Verweij FJ, Kamermans A, Schäfer R, Beerling E, et al. In vivo imaging reveals extracellular vesicle-mediated phenocopying of metastatic behavior. Cell 2015;161:1046–57.
-
(2015)
Cell
, vol.161
, pp. 1046-1057
-
-
Zomer, A.1
Maynard, C.2
Verweij, F.J.3
Kamermans, A.4
Schäfer, R.5
Beerling, E.6
-
22
-
-
84866093563
-
Tumour-secreted mir-9 promotes endothelial cell migration and angiogenesis by activating the jak-stat pathway
-
Zhuang G, Wu X, Jiang Z, Kasman I, Yao J, Guan Y, et al. Tumour-secreted miR-9 promotes endothelial cell migration and angiogenesis by activating the JAK-STAT pathway. EMBO J 2012;31:3513–23.
-
(2012)
EMBO J
, vol.31
, pp. 3513-3523
-
-
Zhuang, G.1
Wu, X.2
Jiang, Z.3
Kasman, I.4
Yao, J.5
Guan, Y.6
-
23
-
-
76649097628
-
Membrane-associated hsp72 from tumor-derived exosomes mediates stat3-dependent immunosuppressive function of mouse and human myeloid-derived suppressor cells
-
Chalmin F, Ladoire S, Mignot G, Vincent J, Bruchard M, Remy-Martin J-P, et al. Membrane-associated Hsp72 from tumor-derived exosomes mediates STAT3-dependent immunosuppressive function of mouse and human myeloid-derived suppressor cells. J Clin Invest 2010;120:457–71.
-
(2010)
J Clin Invest
, vol.120
, pp. 457-471
-
-
Chalmin, F.1
Ladoire, S.2
Mignot, G.3
Vincent, J.4
Bruchard, M.5
Remy-Martin, J.-P.6
-
24
-
-
84936980504
-
Glypican-1 identifies cancer exosomes and detects early pancreatic cancer
-
Melo SA, Luecke LB, Kahlert C, Fernandez AF, Gammon ST, Kaye J, et al. Glypican-1 identifies cancer exosomes and detects early pancreatic cancer. Nature 2015;523:177–82.
-
(2015)
Nature
, vol.523
, pp. 177-182
-
-
Melo, S.A.1
Luecke, L.B.2
Kahlert, C.3
Fernandez, A.F.4
Gammon, S.T.5
Kaye, J.6
-
25
-
-
84929224664
-
Chip-based analysis of exosomal mrna mediating drug resistance in glioblastoma
-
Shao H, Chung J, Lee K, Balaj L, Min C, Carter BS, et al. Chip-based analysis of exosomal mRNA mediating drug resistance in glioblastoma. Nat Commun 2015;6:6999.
-
(2015)
Nat Commun
, vol.6
, pp. 6999
-
-
Shao, H.1
Chung, J.2
Lee, K.3
Balaj, L.4
Min, C.5
Carter, B.S.6
-
26
-
-
70350457821
-
Osteosarcoma originates from mesenchymal stem cells in consequence of aneuploidization and genomic loss of cdkn2
-
Mohseny AB, Szuhai K, Romeo S, Buddingh EP, Briaire-de Bruijn I, de Jong D, et al. Osteosarcoma originates from mesenchymal stem cells in consequence of aneuploidization and genomic loss of Cdkn2. J Pathol 2009; 219:294–305.
-
(2009)
J Pathol
, vol.219
, pp. 294-305
-
-
Mohseny, A.B.1
Szuhai, K.2
Romeo, S.3
Buddingh, E.P.4
Briaire-De Bruijn, I.5
De Jong, D.6
-
27
-
-
84930470918
-
Aven-mediated checkpoint kinase control regulates proliferation and resistance to chemotherapy in conventional osteosarcoma
-
Baranski Z, Booij TH, Cleton-Jansen A-M, Price LS, van de Water B, Bovée JVMG, et al. Aven-mediated checkpoint kinase control regulates proliferation and resistance to chemotherapy in conventional osteosarcoma. J Pathol 2015;236:348–59.
-
(2015)
J Pathol
, vol.236
, pp. 348-359
-
-
Baranski, Z.1
Booij, T.H.2
Cleton-Jansen, A.-M.3
Price, L.S.4
Van De Water, B.5
Bovée, J.V.M.G.6
-
28
-
-
84938697816
-
Human bone marrow- and adipose-mesenchymal stem cells secrete exosomes enriched in distinctive mirna and trna species
-
Baglio SR, Rooijers K, Koppers-Lalic D, Verweij FJ, Pérez Lanzón M, Zini N, et al. Human bone marrow- and adipose-mesenchymal stem cells secrete exosomes enriched in distinctive miRNA and tRNA species. Stem Cell Res Ther 2015;6:127.
-
(2015)
Stem Cell Res Ther
, vol.6
, pp. 127
-
-
Baglio, S.R.1
Rooijers, K.2
Koppers-Lalic, D.3
Verweij, F.J.4
Pérez Lanzón, M.5
Zini, N.6
-
29
-
-
77951749301
-
Adipose-derived mesenchymal stem cells as stable source of tumor necrosis factor-related apoptosis-inducing ligand delivery for cancer therapy
-
Grisendi G, Bussolari R, Cafarelli L, Petak I, Rasini V, Veronesi E, et al. Adipose-derived mesenchymal stem cells as stable source of tumor necrosis factor-related apoptosis-inducing ligand delivery for cancer therapy. Cancer Res 2010;70:3718–29.
-
(2010)
Cancer Res
, vol.70
, pp. 3718-3729
-
-
Grisendi, G.1
Bussolari, R.2
Cafarelli, L.3
Petak, I.4
Rasini, V.5
Veronesi, E.6
-
30
-
-
85055608701
-
Plasma vesicle mirnas for therapy response monitoring in hodgkin lymphoma patients
-
van Eijndhoven MAJ, Zijlstra JM, Groenewegen NJ, Drees EEE, van Niele S, Baglio SR, et al. Plasma vesicle miRNAs for therapy response monitoring in Hodgkin lymphoma patients. JCI Insight 2016;1: e89631.
-
(2016)
JCI Insight
, vol.1
, pp. e89631
-
-
Van Eijndhoven, M.A.J.1
Zijlstra, J.M.2
Groenewegen, N.J.3
Drees, E.E.E.4
Van Niele, S.5
Baglio, S.R.6
-
31
-
-
84924629414
-
Moderated estimation of fold change and dispersion for rna-seq data with deseq2
-
Love MI, Huber W, Anders S. Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2. Genome Biol 2014;15:550.
-
(2014)
Genome Biol
, vol.15
, pp. 550
-
-
Love, M.I.1
Huber, W.2
Anders, S.3
-
32
-
-
84956629623
-
Sensing of latent ebv infection through exosomal transfer of 50pppRna
-
Baglio SR, van Eijndhoven MAJ, Koppers-Lalic D, Berenguer J, Lougheed SM, Gibbs S, et al. Sensing of latent EBV infection through exosomal transfer of 50pppRNA. Proc Natl Acad Sci U S A 2016;113: E587–9.
-
(2016)
Proc Natl Acad Sci U S A
, vol.113
, pp. E587-E589
-
-
Baglio, S.R.1
Van Eijndhoven, M.A.J.2
Koppers-Lalic, D.3
Berenguer, J.4
Lougheed, S.M.5
Gibbs, S.6
-
33
-
-
84961390149
-
Scs macrophages suppress melanoma by restricting tumor-derived vesicle-b cell interactions
-
Pucci F, Garris C, Lai CP, Newton A, Pfirschke C, Engblom C, et al. SCS macrophages suppress melanoma by restricting tumor-derived vesicle-B cell interactions. Science 2016;352:242–6.
-
(2016)
Science
, vol.352
, pp. 242-246
-
-
Pucci, F.1
Garris, C.2
Lai, C.P.3
Newton, A.4
Pfirschke, C.5
Engblom, C.6
-
34
-
-
0022891340
-
Tumors: Wounds that do not heal. Similarities between tumor stroma generation and wound healing
-
Dvorak HF. Tumors: wounds that do not heal. Similarities between tumor stroma generation and wound healing. N Engl J Med 1986;315:1650–9.
-
(1986)
N Engl J Med
, vol.315
, pp. 1650-1659
-
-
Dvorak, H.F.1
-
35
-
-
79957617918
-
Concise review: Mesenchymal stem cell tumor-homing: Detection methods in disease model systems
-
Reagan MR, Kaplan DL. Concise review: mesenchymal stem cell tumor-homing: detection methods in disease model systems. Stem Cells 2011; 29:920–7.
-
(2011)
Stem Cells
, vol.29
, pp. 920-927
-
-
Reagan, M.R.1
Kaplan, D.L.2
-
36
-
-
84885099905
-
Mesenchymal stromal cells: Sensors and switchers of inflammation
-
Bernardo ME, Fibbe WE. Mesenchymal stromal cells: sensors and switchers of inflammation. Cell Stem Cell 2013;13:392–402.
-
(2013)
Cell Stem Cell
, vol.13
, pp. 392-402
-
-
Bernardo, M.E.1
Fibbe, W.E.2
-
37
-
-
70350150677
-
Interleukin-6 maintains bone marrow-derived mesenchymal stem cell stemness by an Erk1/2-dependent mechanism
-
Pricola KL, Kuhn NZ, Haleem-Smith H, Song Y, Tuan RS. Interleukin-6 maintains bone marrow-derived mesenchymal stem cell stemness by an ERK1/2-dependent mechanism. J Cell Biochem 2009;108:577–88.
-
(2009)
J Cell Biochem
, vol.108
, pp. 577-588
-
-
Pricola, K.L.1
Kuhn, N.Z.2
Haleem-Smith, H.3
Song, Y.4
Tuan, R.S.5
-
38
-
-
84864503916
-
Micrornas bind to toll-like receptors to induce prometastatic inflammatory response
-
Fabbri M, Paone A, Calore F, Galli R, Gaudio E, Santhanam R, et al. MicroRNAs bind to Toll-like receptors to induce prometastatic inflammatory response. Proc Natl Acad Sci U S A 2012;109:E2110–6.
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, pp. E2110-E2116
-
-
Fabbri, M.1
Paone, A.2
Calore, F.3
Galli, R.4
Gaudio, E.5
Santhanam, R.6
-
39
-
-
84908275360
-
Exosome transfer from stromal to breast cancer cells regulates therapy resistance pathways
-
Boelens MC, Wu TJ, Nabet BY, Xu B, Qiu Y, Yoon T, et al. Exosome transfer from stromal to breast cancer cells regulates therapy resistance pathways. Cell 2014;159:499–513.
-
(2014)
Cell
, vol.159
, pp. 499-513
-
-
Boelens, M.C.1
Wu, T.J.2
Nabet, B.Y.3
Xu, B.4
Qiu, Y.5
Yoon, T.6
-
40
-
-
84929156225
-
Extracellular vesicles from neural stem cells transfer ifn-g via ifngr1 to activate stat1 signaling in target cells
-
Cossetti C, Iraci N, Mercer TR, Leonardi T, Alpi E, Drago D, et al. Extracellular vesicles from neural stem cells transfer IFN-g via Ifngr1 to activate Stat1 signaling in target cells. Mol Cell 2014;56:193–204.
-
(2014)
Mol Cell
, vol.56
, pp. 193-204
-
-
Cossetti, C.1
Iraci, N.2
Mercer, T.R.3
Leonardi, T.4
Alpi, E.5
Drago, D.6
-
41
-
-
80052384534
-
Blast-derived microvesicles in sera from patients with acute myeloid leukemia suppress natural killer cell function via membrane-associated transforming growth factor-b1
-
Szczepanski MJ, Szajnik M, Welsh A, Whiteside TL, Boyiadzis M. Blast-derived microvesicles in sera from patients with acute myeloid leukemia suppress natural killer cell function via membrane-associated transforming growth factor-b1. Haematologica 2011;96:1302–9.
-
(2011)
Haematologica
, vol.96
, pp. 1302-1309
-
-
Szczepanski, M.J.1
Szajnik, M.2
Welsh, A.3
Whiteside, T.L.4
Boyiadzis, M.5
-
42
-
-
33744928376
-
A membrane form of tnf-alpha presented by exosomes delays t-cell activation-induced cell death
-
Zhang H-G, Liu C, Su K, Su K, Yu S, Zhang L, et al. A membrane form of TNF-alpha presented by exosomes delays T-cell activation-induced cell death. J Immunol 2006;176:7385–93.
-
(2006)
J Immunol
, vol.176
, pp. 7385-7393
-
-
Zhang, H.-G.1
Liu, C.2
Su, K.3
Su, K.4
Yu, S.5
Zhang, L.6
-
43
-
-
41449107062
-
Unconventional secretion of fibroblast growth factor 2 and galectin-1 does not require shedding of plasma membrane-derived vesicles
-
Seelenmeyer C, Stegmayer C, Nickel W. Unconventional secretion of fibroblast growth factor 2 and galectin-1 does not require shedding of plasma membrane-derived vesicles. FEBS Lett 2008;582:1362–8.
-
(2008)
FEBS Lett
, vol.582
, pp. 1362-1368
-
-
Seelenmeyer, C.1
Stegmayer, C.2
Nickel, W.3
-
44
-
-
78649958307
-
Cancer exosomes trigger fibroblast to myofibroblast differentiation
-
Webber J, Steadman R, Mason MD, Tabi Z, Clayton A. Cancer exosomes trigger fibroblast to myofibroblast differentiation. Cancer Res 2010;70: 9621–30.
-
(2010)
Cancer Res
, vol.70
, pp. 9621-9630
-
-
Webber, J.1
Steadman, R.2
Mason, M.D.3
Tabi, Z.4
Clayton, A.5
-
45
-
-
0031873335
-
Expression of transforming growth factor beta isoforms in osteosarcoma variants: Association of tgf beta 1 with high-grade osteosarcomas
-
Franchi A, Arganini L, Baroni G, Calzolari A, Capanna R, Campanacci D, et al. Expression of transforming growth factor beta isoforms in osteosarcoma variants: association of TGF beta 1 with high-grade osteosarcomas. J Pathol. 1998;185:284–9
-
(1998)
J Pathol
, vol.185
, pp. 284-289
-
-
Franchi, A.1
Arganini, L.2
Baroni, G.3
Calzolari, A.4
Capanna, R.5
Campanacci, D.6
-
46
-
-
0028070653
-
Expression of transforming growth factor-beta (tgf-beta) receptors, tgf-beta 1 and tgf-beta 2 production and autocrine growth control in osteosarcoma cells
-
Kloen P, Jennings CL, Gebhardt MC, Springfield DS, Mankin HJ. Expression of transforming growth factor-beta (TGF-beta) receptors, TGF-beta 1 and TGF-beta 2 production and autocrine growth control in osteosarcoma cells. Int J Cancer 1994;58:440–5.
-
(1994)
Int J Cancer
, vol.58
, pp. 440-445
-
-
Kloen, P.1
Jennings, C.L.2
Gebhardt, M.C.3
Springfield, D.S.4
Mankin, H.J.5
-
47
-
-
84908161000
-
Revisiting stat3 signalling in cancer: New and unexpected biological functions
-
Yu H, Lee H, Herrmann A, Buettner R, Jove R. Revisiting STAT3 signalling in cancer: new and unexpected biological functions. Nat Rev Cancer 2014; 14:736–46.
-
(2014)
Nat Rev Cancer
, vol.14
, pp. 736-746
-
-
Yu, H.1
Lee, H.2
Herrmann, A.3
Buettner, R.4
Jove, R.5
-
48
-
-
84884902907
-
Genome-wide analyses on high-grade osteosarcoma: Making sense of a genomically most unstable tumor
-
Kuijjer ML, Hogendoorn PCW, Cleton-Jansen A-M. Genome-wide analyses on high-grade osteosarcoma: making sense of a genomically most unstable tumor. Int J Cancer 2013;133:2512–21.
-
(2013)
Int J Cancer
, vol.133
, pp. 2512-2521
-
-
Kuijjer, M.L.1
Hogendoorn, P.C.W.2
Cleton-Jansen, A.-M.3
-
49
-
-
0035907240
-
Identification of novel tgf-beta/ smad gene targets in dermal fibroblasts using a combined cdna microarray/promoter transactivation approach
-
Verrecchia F, Chu ML, Mauviel A. Identification of novel TGF-beta/ Smad gene targets in dermal fibroblasts using a combined cDNA microarray/promoter transactivation approach. J Biol Chem 2001;276: 17058–62.
-
(2001)
J Biol Chem
, vol.276
, pp. 17058-17062
-
-
Verrecchia, F.1
Chu, M.L.2
Mauviel, A.3
-
50
-
-
84930170395
-
Pancreatic cancer exosomes initiate pre-metastatic niche formation in the liver
-
Costa-Silva B, Aiello NM, Ocean AJ, Singh S, Zhang H, Thakur BK, et al. Pancreatic cancer exosomes initiate pre-metastatic niche formation in the liver. Nat Cell Biol 2015;17:816–26.
-
(2015)
Nat Cell Biol
, vol.17
, pp. 816-826
-
-
Costa-Silva, B.1
Aiello, N.M.2
Ocean, A.J.3
Singh, S.4
Zhang, H.5
Thakur, B.K.6
-
51
-
-
84947723880
-
Tumour exosome integrins determine organotropic metastasis
-
Hoshino A, Costa-Silva B, Shen T-L, Rodrigues G, Hashimoto A, Tesic Mark M, et al. Tumour exosome integrins determine organotropic metastasis. Nature 2015;527:329–35.
-
(2015)
Nature
, vol.527
, pp. 329-335
-
-
Hoshino, A.1
Costa-Silva, B.2
Shen, T.-L.3
Rodrigues, G.4
Hashimoto, A.5
Tesic Mark, M.6
-
52
-
-
84946559154
-
Micro-environment-induced pten loss by exosomal microrna primes brain metastasis outgrowth
-
Zhang L, Zhang S, Yao J, Lowery FJ, Zhang Q, Huang W-C, et al. Micro-environment-induced PTEN loss by exosomal microRNA primes brain metastasis outgrowth. Nature 2015;527:100–4.
-
(2015)
Nature
, vol.527
, pp. 100-104
-
-
Zhang, L.1
Zhang, S.2
Yao, J.3
Lowery, F.J.4
Zhang, Q.5
Huang, W.-C.6
-
53
-
-
70350778443
-
An epigenetic switch involving nf-kappab, lin28, let-7 microrna, and il6 links inflammation to cell transformation
-
Iliopoulos D, Hirsch HA, Struhl K. An epigenetic switch involving NF-kappaB, Lin28, Let-7 MicroRNA, and IL6 links inflammation to cell transformation. Cell 2009;139:693–706.
-
(2009)
Cell
, vol.139
, pp. 693-706
-
-
Iliopoulos, D.1
Hirsch, H.A.2
Struhl, K.3
-
54
-
-
84865422083
-
Interleukin-6 signaling pathway in targeted therapy for cancer
-
Guo Y, Xu F, Lu T, Duan Z, Zhang Z. Interleukin-6 signaling pathway in targeted therapy for cancer. Cancer Treat Rev 2012;38:904–10.
-
(2012)
Cancer Treat Rev
, vol.38
, pp. 904-910
-
-
Guo, Y.1
Xu, F.2
Lu, T.3
Duan, Z.4
Zhang, Z.5
-
55
-
-
84899107867
-
Effect of the cytokine levels in serum on osteosarcoma
-
Xiao H, Chen L, Luo G, Son H, Prectoni JH, Zheng W. Effect of the cytokine levels in serum on osteosarcoma. Tumour Biol 2014;35:1023–8.
-
(2014)
Tumour Biol
, vol.35
, pp. 1023-1028
-
-
Xiao, H.1
Chen, L.2
Luo, G.3
Son, H.4
Prectoni, J.H.5
Zheng, W.6
-
56
-
-
0242361563
-
Cytokine and cytokine receptor serum levels in adult bone sarcoma patients: Correlations with local tumor extent and prognosis
-
Rutkowski P, Kamin´ ska J, Kowalska M, Ruka W, Steffen J. Cytokine and cytokine receptor serum levels in adult bone sarcoma patients: correlations with local tumor extent and prognosis. J Surg Oncol 2003;84:151–9.
-
(2003)
J Surg Oncol
, vol.84
, pp. 151-159
-
-
Rutkowski, P.1
Kamin´ ska, J.2
Kowalska, M.3
Ruka, W.4
Steffen, J.5
-
57
-
-
58149236744
-
Roles of tgfbeta in metastasis
-
Padua D, Massague J. Roles of TGFbeta in metastasis. Cell Res 2009; 19:89–102.
-
(2009)
Cell Res
, vol.19
, pp. 89-102
-
-
Padua, D.1
Massague, J.2
-
58
-
-
84925818452
-
Stromal gene expression defines poor-prognosis subtypes in colorectal cancer
-
Calon A, Lonardo E, Berenguer-Llergo A, Espinet E, Hernando-Momblona X, Iglesias M, et al. Stromal gene expression defines poor-prognosis subtypes in colorectal cancer. Nat Genet 2015;47:320–9.
-
(2015)
Nat Genet
, vol.47
, pp. 320-329
-
-
Calon, A.1
Lonardo, E.2
Berenguer-Llergo, A.3
Espinet, E.4
Hernando-Momblona, X.5
Iglesias, M.6
-
59
-
-
84925446437
-
Differentiation of tumour-promoting stromal myofibroblasts by cancer exosomes
-
Webber JP, Spary LK, Sanders AJ, Chowdhury R, Jiang WG, Steadman R, et al. Differentiation of tumour-promoting stromal myofibroblasts by cancer exosomes. Oncogene 2015;34:290–302.
-
(2015)
Oncogene
, vol.34
, pp. 290-302
-
-
Webber, J.P.1
Spary, L.K.2
Sanders, A.J.3
Chowdhury, R.4
Jiang, W.G.5
Steadman, R.6
-
61
-
-
84922668738
-
Targeting the tgfb pathway for cancer therapy
-
Neuzillet C, Tijeras-Raballand A, Cohen R, Cros J, Faivre S, Raymond E, et al. Targeting the TGFb pathway for cancer therapy. Pharmacol Ther 2015;147:22–31.
-
(2015)
Pharmacol Ther
, vol.147
, pp. 22-31
-
-
Neuzillet, C.1
Tijeras-Raballand, A.2
Cohen, R.3
Cros, J.4
Faivre, S.5
Raymond, E.6
|