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Volumn 7, Issue JUL, 2017, Pages

The impact of the tumor microenvironment on the properties of glioma stem-like cells

Author keywords

Glioblastoma; Glioma stem like cells; Microenvironment; Therapy resistance; Transdifferentiation

Indexed keywords

CD28 ANTIGEN; COLONY STIMULATING FACTOR 1; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; INTERLEUKIN 10; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; MONOCYTE CHEMOTACTIC PROTEIN 1; NATURAL KILLER CELL RECEPTOR NKG2D; NOTCH RECEPTOR; OSTEOPONTIN; TRANSFORMING GROWTH FACTOR BETA;

EID: 85024111918     PISSN: None     EISSN: 2234943X     Source Type: Journal    
DOI: 10.3389/fonc.2017.00143     Document Type: Review
Times cited : (48)

References (93)
  • 1
    • 0028091194 scopus 로고
    • A cell initiating human acute myeloid leukaemia after transplantation into SCID mice
    • Lapidot T, Sirard C, Vormoor J, Murdoch B, Hoang T, Caceres-Cortes J, et al. A cell initiating human acute myeloid leukaemia after transplantation into SCID mice. Nature (1994) 367(6464):645-8. doi:10.1038/367645a0
    • (1994) Nature , vol.367 , Issue.6464 , pp. 645-648
    • Lapidot, T.1    Sirard, C.2    Vormoor, J.3    Murdoch, B.4    Hoang, T.5    Caceres-Cortes, J.6
  • 2
    • 84884558125 scopus 로고    scopus 로고
    • Unravelling cancer stem cell potential
    • Beck B, Blanpain C. Unravelling cancer stem cell potential. Nat Rev Cancer (2013) 13(10):727-38. doi:10.1038/nrc3597
    • (2013) Nat Rev Cancer , vol.13 , Issue.10 , pp. 727-738
    • Beck, B.1    Blanpain, C.2
  • 3
    • 84862517728 scopus 로고    scopus 로고
    • Cancer stem cells: current status and evolving complexities
    • Visvader JE, Lindeman GJ. Cancer stem cells: current status and evolving complexities. Cell Stem Cell (2012) 10(6):717-28. doi:10.1016/j.stem.2012.05.007
    • (2012) Cell Stem Cell , vol.10 , Issue.6 , pp. 717-728
    • Visvader, J.E.1    Lindeman, G.J.2
  • 4
    • 79959681732 scopus 로고    scopus 로고
    • In vivo clonal analysis reveals self-renewing and multipotent adult neural stem cell characteristics
    • Bonaguidi MA, Wheeler MA, Shapiro JS, Stadel RP, Sun GJ, Ming GL, et al. In vivo clonal analysis reveals self-renewing and multipotent adult neural stem cell characteristics. Cell (2011) 145(7):1142-55. doi:10.1016/j.cell.2011.05.024
    • (2011) Cell , vol.145 , Issue.7 , pp. 1142-1155
    • Bonaguidi, M.A.1    Wheeler, M.A.2    Shapiro, J.S.3    Stadel, R.P.4    Sun, G.J.5    Ming, G.L.6
  • 5
    • 84964334475 scopus 로고    scopus 로고
    • Live imaging of adult neural stem cells in rodents
    • Ortega F, Costa MR. Live imaging of adult neural stem cells in rodents. Front Neurosci (2016) 10:78. doi:10.3389/fnins.2016.00078
    • (2016) Front Neurosci , vol.10 , pp. 78
    • Ortega, F.1    Costa, M.R.2
  • 6
    • 0036737914 scopus 로고    scopus 로고
    • Human cortical glial tumors contain neural stem-like cells expressing astroglial and neuronal markers in vitro
    • Ignatova TN, Kukekov VG, Laywell ED, Suslov ON, Vrionis FD, Steindler DA. Human cortical glial tumors contain neural stem-like cells expressing astroglial and neuronal markers in vitro. Glia (2002) 39(3):193-206. doi:10.1002/glia.10094
    • (2002) Glia , vol.39 , Issue.3 , pp. 193-206
    • Ignatova, T.N.1    Kukekov, V.G.2    Laywell, E.D.3    Suslov, O.N.4    Vrionis, F.D.5    Steindler, D.A.6
  • 8
    • 4944250781 scopus 로고    scopus 로고
    • Isolation and characterization of tumorigenic, stem-like neural precursors from human glioblastoma
    • Galli R, Binda E, Orfanelli U, Cipelletti B, Gritti A, De Vitis S, et al. Isolation and characterization of tumorigenic, stem-like neural precursors from human glioblastoma. Cancer Res (2004) 64(19):7011-21. doi:10.1158/0008-5472.CAN-04-1364
    • (2004) Cancer Res , vol.64 , Issue.19 , pp. 7011-7021
    • Galli, R.1    Binda, E.2    Orfanelli, U.3    Cipelletti, B.4    Gritti, A.5    De Vitis, S.6
  • 9
    • 33845317573 scopus 로고    scopus 로고
    • Glioma stem cells promote radioresistance by preferential activation of the DNA damage response
    • Bao S, Wu Q, McLendon RE, Hao Y, Shi Q, Hjelmeland AB, et al. Glioma stem cells promote radioresistance by preferential activation of the DNA damage response. Nature (2006) 444(7120):756-60. doi:10.1038/nature05236
    • (2006) Nature , vol.444 , Issue.7120 , pp. 756-760
    • Bao, S.1    Wu, Q.2    McLendon, R.E.3    Hao, Y.4    Shi, Q.5    Hjelmeland, A.B.6
  • 10
    • 84883656941 scopus 로고    scopus 로고
    • Mesenchymal differentiation mediated by NF-kappaB promotes radiation resistance in glioblastoma
    • Bhat KP, Balasubramaniyan V, Vaillant B, Ezhilarasan R, Hummelink K, Hollingsworth F, et al. Mesenchymal differentiation mediated by NF-kappaB promotes radiation resistance in glioblastoma. Cancer Cell (2013) 24(3):331-46. doi:10.1016/j.ccr.2013.08.001
    • (2013) Cancer Cell , vol.24 , Issue.3 , pp. 331-346
    • Bhat, K.P.1    Balasubramaniyan, V.2    Vaillant, B.3    Ezhilarasan, R.4    Hummelink, K.5    Hollingsworth, F.6
  • 12
    • 84908219402 scopus 로고    scopus 로고
    • Glioblastoma heterogeneity and cancer cell plasticity
    • Friedmann-Morvinski D. Glioblastoma heterogeneity and cancer cell plasticity. Crit Rev Oncog (2014) 19(5):327-36. doi:10.1615/CritRevOncog.2014011777
    • (2014) Crit Rev Oncog , vol.19 , Issue.5 , pp. 327-336
    • Friedmann-Morvinski, D.1
  • 14
    • 84884377472 scopus 로고    scopus 로고
    • Tumour heterogeneity and cancer cell plasticity
    • Meacham CE, Morrison SJ. Tumour heterogeneity and cancer cell plasticity. Nature (2013) 501(7467):328-37. doi:10.1038/nature12624
    • (2013) Nature , vol.501 , Issue.7467 , pp. 328-337
    • Meacham, C.E.1    Morrison, S.J.2
  • 15
    • 9244241576 scopus 로고    scopus 로고
    • Identification of human brain tumour initiating cells
    • Singh SK, Hawkins C, Clarke ID, Squire JA, Bayani J, Hide T, et al. Identification of human brain tumour initiating cells. Nature (2004) 432(7015):396-401. doi:10.1038/nature03128
    • (2004) Nature , vol.432 , Issue.7015 , pp. 396-401
    • Singh, S.K.1    Hawkins, C.2    Clarke, I.D.3    Squire, J.A.4    Bayani, J.5    Hide, T.6
  • 16
    • 76549120193 scopus 로고    scopus 로고
    • The AC133 epitope, but not the CD133 protein, is lost upon cancer stem cell differentiation
    • Kemper K, Sprick MR, de Bree M, Scopelliti A, Vermeulen L, Hoek M, et al. The AC133 epitope, but not the CD133 protein, is lost upon cancer stem cell differentiation. Cancer Res (2010) 70(2):719-29. doi:10.1158/0008-5472.CAN-09-1820
    • (2010) Cancer Res , vol.70 , Issue.2 , pp. 719-729
    • Kemper, K.1    Sprick, M.R.2    de Bree, M.3    Scopelliti, A.4    Vermeulen, L.5    Hoek, M.6
  • 18
    • 84890616428 scopus 로고    scopus 로고
    • Cancer stem cells: a minor cancer subpopulation that redefines global cancer features
    • Enderling H, Hlatky L, Hahnfeldt P. Cancer stem cells: a minor cancer subpopulation that redefines global cancer features. Front Oncol (2013) 3:76. doi:10.3389/fonc.2013.00076
    • (2013) Front Oncol , vol.3 , pp. 76
    • Enderling, H.1    Hlatky, L.2    Hahnfeldt, P.3
  • 19
    • 84864332814 scopus 로고    scopus 로고
    • Fluorescence-guided surgical sampling of glioblastoma identifies phenotypically distinct tumour-initiating cell populations in the tumour mass and margin
    • Piccirillo SG, Dietz S, Madhu B, Griffiths J, Price SJ, Collins VP, et al. Fluorescence-guided surgical sampling of glioblastoma identifies phenotypically distinct tumour-initiating cell populations in the tumour mass and margin. Br J Cancer (2012) 107(3):462-8. doi:10.1038/bjc.2012.271
    • (2012) Br J Cancer , vol.107 , Issue.3 , pp. 462-468
    • Piccirillo, S.G.1    Dietz, S.2    Madhu, B.3    Griffiths, J.4    Price, S.J.5    Collins, V.P.6
  • 20
    • 84896697126 scopus 로고    scopus 로고
    • Glioblastomas are composed of genetically divergent clones with distinct tumourigenic potential and variable stem cell-associated phenotypes
    • Stieber D, Golebiewska A, Evers L, Lenkiewicz E, Brons NH, Nicot N, et al. Glioblastomas are composed of genetically divergent clones with distinct tumourigenic potential and variable stem cell-associated phenotypes. Acta Neuropathol (2014) 127(2):203-19. doi:10.1007/s00401-013-1196-4
    • (2014) Acta Neuropathol , vol.127 , Issue.2 , pp. 203-219
    • Stieber, D.1    Golebiewska, A.2    Evers, L.3    Lenkiewicz, E.4    Brons, N.H.5    Nicot, N.6
  • 22
    • 84933517549 scopus 로고    scopus 로고
    • The role of glioma stem cells in chemotherapy resistance and glioblastoma multiforme recurrence
    • Auffinger B, Spencer D, Pytel P, Ahmed AU, Lesniak MS. The role of glioma stem cells in chemotherapy resistance and glioblastoma multiforme recurrence. Expert Rev Neurother (2015) 15(7):741-52. doi:10.1586/14737175.2015.1051968
    • (2015) Expert Rev Neurother , vol.15 , Issue.7 , pp. 741-752
    • Auffinger, B.1    Spencer, D.2    Pytel, P.3    Ahmed, A.U.4    Lesniak, M.S.5
  • 23
    • 0020026541 scopus 로고
    • Age-related chemosensitivity of stem cells from human malignant brain tumours
    • Rosenblum ML, Gerosa M, Dougherty DV, Reese C, Barger GR, Davis RL, et al. Age-related chemosensitivity of stem cells from human malignant brain tumours. Lancet (1982) 1(8277):885-7. doi:10.1016/S0140-6736(82)92154-7
    • (1982) Lancet , vol.1 , Issue.8277 , pp. 885-887
    • Rosenblum, M.L.1    Gerosa, M.2    Dougherty, D.V.3    Reese, C.4    Barger, G.R.5    Davis, R.L.6
  • 25
    • 82955195440 scopus 로고    scopus 로고
    • Heterogeneity of primary glioblastoma cells in the expression of caspase-8 and the response to TRAIL-induced apoptosis
    • Qi L, Bellail AC, Rossi MR, Zhang Z, Pang H, Hunter S, et al. Heterogeneity of primary glioblastoma cells in the expression of caspase-8 and the response to TRAIL-induced apoptosis. Apoptosis (2011) 16(11):1150-64. doi:10.1007/s10495-011-0645-6
    • (2011) Apoptosis , vol.16 , Issue.11 , pp. 1150-1164
    • Qi, L.1    Bellail, A.C.2    Rossi, M.R.3    Zhang, Z.4    Pang, H.5    Hunter, S.6
  • 26
    • 84894276198 scopus 로고    scopus 로고
    • Response of primary glioblastoma cells to therapy is patient specific and independent of cancer stem cell phenotype
    • Fouse SD, Nakamura JL, James CD, Chang S, Costello JF. Response of primary glioblastoma cells to therapy is patient specific and independent of cancer stem cell phenotype. Neuro Oncol (2014) 16(3):361-71. doi:10.1093/neuonc/not223
    • (2014) Neuro Oncol , vol.16 , Issue.3 , pp. 361-371
    • Fouse, S.D.1    Nakamura, J.L.2    James, C.D.3    Chang, S.4    Costello, J.F.5
  • 27
    • 67649908864 scopus 로고    scopus 로고
    • Adult neural stem cells in the mammalian central nervous system
    • Ma DK, Bonaguidi MA, Ming GL, Song H. Adult neural stem cells in the mammalian central nervous system. Cell Res (2009) 19(6):672-82. doi:10.1038/cr.2009.56
    • (2009) Cell Res , vol.19 , Issue.6 , pp. 672-682
    • Ma, D.K.1    Bonaguidi, M.A.2    Ming, G.L.3    Song, H.4
  • 29
    • 70350225829 scopus 로고    scopus 로고
    • The hypoxic microenvironment maintains glioblastoma stem cells and promotes reprogramming towards a cancer stem cell phenotype
    • Heddleston JM, Li Z, McLendon RE, Hjelmeland AB, Rich JN. The hypoxic microenvironment maintains glioblastoma stem cells and promotes reprogramming towards a cancer stem cell phenotype. Cell Cycle (2009) 8(20):3274-84. doi:10.4161/cc.8.20.9701
    • (2009) Cell Cycle , vol.8 , Issue.20 , pp. 3274-3284
    • Heddleston, J.M.1    Li, Z.2    McLendon, R.E.3    Hjelmeland, A.B.4    Rich, J.N.5
  • 30
    • 65749106405 scopus 로고    scopus 로고
    • Hypoxia-inducible factors regulate tumorigenic capacity of glioma stem cells
    • Li Z, Bao S, Wu Q, Wang H, Eyler C, Sathornsumetee S, et al. Hypoxia-inducible factors regulate tumorigenic capacity of glioma stem cells. Cancer Cell (2009) 15(6):501-13. doi:10.1016/j.ccr.2009.03.018
    • (2009) Cancer Cell , vol.15 , Issue.6 , pp. 501-513
    • Li, Z.1    Bao, S.2    Wu, Q.3    Wang, H.4    Eyler, C.5    Sathornsumetee, S.6
  • 31
    • 77957607057 scopus 로고    scopus 로고
    • Endothelial cells dynamically compete for the tip cell position during angiogenic sprouting
    • Jakobsson L, Franco CA, Bentley K, Collins RT, Ponsioen B, Aspalter IM, et al. Endothelial cells dynamically compete for the tip cell position during angiogenic sprouting. Nat Cell Biol (2010) 12(10):943-53. doi:10.1038/ncb2103
    • (2010) Nat Cell Biol , vol.12 , Issue.10 , pp. 943-953
    • Jakobsson, L.1    Franco, C.A.2    Bentley, K.3    Collins, R.T.4    Ponsioen, B.5    Aspalter, I.M.6
  • 32
    • 33747874155 scopus 로고    scopus 로고
    • Notch pathway inhibition depletes stem-like cells and blocks engraftment in embryonal brain tumors
    • Fan X, Matsui W, Khaki L, Stearns D, Chun J, Li YM, et al. Notch pathway inhibition depletes stem-like cells and blocks engraftment in embryonal brain tumors. Cancer Res (2006) 66(15):7445-52. doi:10.1158/0008-5472.CAN-06-0858
    • (2006) Cancer Res , vol.66 , Issue.15 , pp. 7445-7452
    • Fan, X.1    Matsui, W.2    Khaki, L.3    Stearns, D.4    Chun, J.5    Li, Y.M.6
  • 33
    • 75349105363 scopus 로고    scopus 로고
    • NOTCH pathway blockade depletes CD133-positive glioblastoma cells and inhibits growth of tumor neurospheres and xenografts
    • Fan X, Khaki L, Zhu TS, Soules ME, Talsma CE, Gul N, et al. NOTCH pathway blockade depletes CD133-positive glioblastoma cells and inhibits growth of tumor neurospheres and xenografts. Stem Cells (2010) 28(1):5-16. doi:10.1002/stem.254
    • (2010) Stem Cells , vol.28 , Issue.1 , pp. 5-16
    • Fan, X.1    Khaki, L.2    Zhu, T.S.3    Soules, M.E.4    Talsma, C.E.5    Gul, N.6
  • 34
    • 80052795862 scopus 로고    scopus 로고
    • Endothelial cells create a stem cell niche in glioblastoma by providing NOTCH ligands that nurture self-renewal of cancer stem-like cells
    • Zhu TS, Costello MA, Talsma CE, Flack CG, Crowley JG, Hamm LL, et al. Endothelial cells create a stem cell niche in glioblastoma by providing NOTCH ligands that nurture self-renewal of cancer stem-like cells. Cancer Res (2011) 71(18):6061-72. doi:10.1158/0008-5472.CAN-10-4269
    • (2011) Cancer Res , vol.71 , Issue.18 , pp. 6061-6072
    • Zhu, T.S.1    Costello, M.A.2    Talsma, C.E.3    Flack, C.G.4    Crowley, J.G.5    Hamm, L.L.6
  • 35
    • 75349091751 scopus 로고    scopus 로고
    • Perivascular nitric oxide activates notch signaling and promotes stem-like character in PDGF-induced glioma cells
    • Charles N, Ozawa T, Squatrito M, Bleau AM, Brennan CW, Hambardzumyan D, et al. Perivascular nitric oxide activates notch signaling and promotes stem-like character in PDGF-induced glioma cells. Cell Stem Cell (2010) 6(2):141-52. doi:10.1016/j.stem.2010.01.001
    • (2010) Cell Stem Cell , vol.6 , Issue.2 , pp. 141-152
    • Charles, N.1    Ozawa, T.2    Squatrito, M.3    Bleau, A.M.4    Brennan, C.W.5    Hambardzumyan, D.6
  • 36
    • 79959969874 scopus 로고    scopus 로고
    • Glioma stem cell proliferation and tumor growth are promoted by nitric oxide synthase-2
    • Eyler CE, Wu Q, Yan K, MacSwords JM, Chandler-Militello D, Misuraca KL, et al. Glioma stem cell proliferation and tumor growth are promoted by nitric oxide synthase-2. Cell (2011) 146(1):53-66. doi:10.1016/j.cell.2011.06.006
    • (2011) Cell , vol.146 , Issue.1 , pp. 53-66
    • Eyler, C.E.1    Wu, Q.2    Yan, K.3    MacSwords, J.M.4    Chandler-Militello, D.5    Misuraca, K.L.6
  • 37
    • 78650153633 scopus 로고    scopus 로고
    • Tumour vascularization via endothelial differentiation of glioblastoma stem-like cells
    • Ricci-Vitiani L, Pallini R, Biffoni M, Todaro M, Invernici G, Cenci T, et al. Tumour vascularization via endothelial differentiation of glioblastoma stem-like cells. Nature (2010) 468(7325):824-8. doi:10.1038/nature09557
    • (2010) Nature , vol.468 , Issue.7325 , pp. 824-828
    • Ricci-Vitiani, L.1    Pallini, R.2    Biffoni, M.3    Todaro, M.4    Invernici, G.5    Cenci, T.6
  • 38
    • 78650098659 scopus 로고    scopus 로고
    • Glioblastoma stem-like cells give rise to tumour endothelium
    • Wang R, Chadalavada K, Wilshire J, Kowalik U, Hovinga KE, Geber A, et al. Glioblastoma stem-like cells give rise to tumour endothelium. Nature (2010) 468(7325):829-33. doi:10.1038/nature09624
    • (2010) Nature , vol.468 , Issue.7325 , pp. 829-833
    • Wang, R.1    Chadalavada, K.2    Wilshire, J.3    Kowalik, U.4    Hovinga, K.E.5    Geber, A.6
  • 40
    • 84863221153 scopus 로고    scopus 로고
    • Neoplastic cells are a rare component in human glioblastoma microvasculature
    • Rodriguez FJ, Orr BA, Ligon KL, Eberhart CG. Neoplastic cells are a rare component in human glioblastoma microvasculature. Oncotarget (2012) 3(1):98-106. doi:10.18632/oncotarget.427
    • (2012) Oncotarget , vol.3 , Issue.1 , pp. 98-106
    • Rodriguez, F.J.1    Orr, B.A.2    Ligon, K.L.3    Eberhart, C.G.4
  • 41
    • 27644557532 scopus 로고    scopus 로고
    • The role of pericytes in cell-mediated formation and maintenance
    • Bergers G, Song S. The role of pericytes in cell-mediated formation and maintenance. Neuro Oncol (2005) 7(4):452-64. doi:10.1215/S1152851705000232
    • (2005) Neuro Oncol , vol.7 , Issue.4 , pp. 452-464
    • Bergers, G.1    Song, S.2
  • 42
    • 84875755046 scopus 로고    scopus 로고
    • Glioblastoma stem cells generate vascular pericytes to support vessel function and tumor growth
    • Cheng L, Huang Z, Zhou W, Wu Q, Donnola S, Liu JK, et al. Glioblastoma stem cells generate vascular pericytes to support vessel function and tumor growth. Cell (2013) 153(1):139-52. doi:10.1016/j.cell.2013.02.021
    • (2013) Cell , vol.153 , Issue.1 , pp. 139-152
    • Cheng, L.1    Huang, Z.2    Zhou, W.3    Wu, Q.4    Donnola, S.5    Liu, J.K.6
  • 43
    • 84929485386 scopus 로고    scopus 로고
    • Endogenous brain pericytes are widely activated and contribute to mouse glioma microvasculature
    • Svensson A, özen I, Genové G, Paul G, Bengzon J. Endogenous brain pericytes are widely activated and contribute to mouse glioma microvasculature. PLoS One (2015) 10(4):e0123553. doi:10.1371/journal.pone.0123553
    • (2015) PLoS One , vol.10 , Issue.4
    • Svensson, A.1    Özen, I.2    Genové, G.3    Paul, G.4    Bengzon, J.5
  • 46
    • 70349501957 scopus 로고    scopus 로고
    • Chemokine CXC receptor 4-mediated glioma tumor tracking by bone marrow-derived neural progenitor/stem cells
    • Xu Q, Yuan X, Xu M, McLafferty F, Hu J, Lee BS, et al. Chemokine CXC receptor 4-mediated glioma tumor tracking by bone marrow-derived neural progenitor/stem cells. Mol Cancer Ther (2009) 8(9):2746-53. doi:10.1158/1535-7163.MCT-09-0273
    • (2009) Mol Cancer Ther , vol.8 , Issue.9 , pp. 2746-2753
    • Xu, Q.1    Yuan, X.2    Xu, M.3    McLafferty, F.4    Hu, J.5    Lee, B.S.6
  • 47
    • 77649189116 scopus 로고    scopus 로고
    • Astrocytes: biology and pathology
    • Sofroniew MV, Vinters HV. Astrocytes: biology and pathology. Acta Neuropathol (2010) 119(1):7-35. doi:10.1007/s00401-009-0619-8
    • (2010) Acta Neuropathol , vol.119 , Issue.1 , pp. 7-35
    • Sofroniew, M.V.1    Vinters, H.V.2
  • 48
    • 0031660778 scopus 로고    scopus 로고
    • Response of astrocytes and oligodendrocytes to injury
    • Yong VW. Response of astrocytes and oligodendrocytes to injury. Ment Retard Dev Disabil Res Rev (1998) 4(3):193-9. doi:10.1002/(SICI)1098-2779(1998)4:3<193::AID-MRDD7>3.0.CO;2-P
    • (1998) Ment Retard Dev Disabil Res Rev , vol.4 , Issue.3 , pp. 193-199
    • Yong, V.W.1
  • 50
    • 84957900747 scopus 로고    scopus 로고
    • Astrocytes promote glioma invasion via the gap junction protein connexin43
    • Sin WC, Aftab Q, Bechberger JF, Leung JH, Chen H, Naus CC. Astrocytes promote glioma invasion via the gap junction protein connexin43. Oncogene (2016) 35(12):1504-16. doi:10.1038/onc.2015.210
    • (2016) Oncogene , vol.35 , Issue.12 , pp. 1504-1516
    • Sin, W.C.1    Aftab, Q.2    Bechberger, J.F.3    Leung, J.H.4    Chen, H.5    Naus, C.C.6
  • 51
    • 85017614562 scopus 로고    scopus 로고
    • Reactive astrocytes potentiate tumor aggressiveness in a murine glioma resection and recurrence model
    • Okolie O, Bago JR, Schmid RS, Irvin DM, Bash RE, Miller CR, et al. Reactive astrocytes potentiate tumor aggressiveness in a murine glioma resection and recurrence model. Neuro Oncol (2016) 18(12):1622-33. doi:10.1093/neuonc/now212.903
    • (2016) Neuro Oncol , vol.18 , Issue.12 , pp. 1622-1633
    • Okolie, O.1    Bago, J.R.2    Schmid, R.S.3    Irvin, D.M.4    Bash, R.E.5    Miller, C.R.6
  • 52
    • 84928918997 scopus 로고    scopus 로고
    • Neuronal activity promotes glioma growth through neuroligin-3 secretion
    • Venkatesh HS, Johung TB, Caretti V, Noll A, Tang Y, Nagaraja S, et al. Neuronal activity promotes glioma growth through neuroligin-3 secretion. Cell (2015) 161(4):803-16. doi:10.1016/j.cell.2015.04.012
    • (2015) Cell , vol.161 , Issue.4 , pp. 803-816
    • Venkatesh, H.S.1    Johung, T.B.2    Caretti, V.3    Noll, A.4    Tang, Y.5    Nagaraja, S.6
  • 54
    • 84928774156 scopus 로고    scopus 로고
    • The future of immune checkpoint therapy
    • Sharma P, Allison JP. The future of immune checkpoint therapy. Science (2015) 348(6230):56-61. doi:10.1126/science.aaa8172
    • (2015) Science , vol.348 , Issue.6230 , pp. 56-61
    • Sharma, P.1    Allison, J.P.2
  • 55
    • 84906312886 scopus 로고    scopus 로고
    • CNS macrophages and peripheral myeloid cells in brain tumours
    • Glass R, Synowitz M. CNS macrophages and peripheral myeloid cells in brain tumours. Acta Neuropathol (2014) 128(3):347-62. doi:10.1007/s00401-014-1274-2
    • (2014) Acta Neuropathol , vol.128 , Issue.3 , pp. 347-362
    • Glass, R.1    Synowitz, M.2
  • 56
    • 0033991158 scopus 로고    scopus 로고
    • Escape of human solid tumors from T-cell recognition: molecular mechanisms and functional significance
    • Marincola FM, Jaffee EM, Hicklin DJ, Ferrone S. Escape of human solid tumors from T-cell recognition: molecular mechanisms and functional significance. Adv Immunol (2000) 74:181-273. doi:10.1016/S0065-2776(08)60911-6
    • (2000) Adv Immunol , vol.74 , pp. 181-273
    • Marincola, F.M.1    Jaffee, E.M.2    Hicklin, D.J.3    Ferrone, S.4
  • 57
    • 84943241524 scopus 로고    scopus 로고
    • Programmed death ligand 1 expression and tumor-infiltrating lymphocytes in glioblastoma
    • Berghoff AS, Kiesel B, Widhalm G, Rajky O, Ricken G, Wöhrer A, et al. Programmed death ligand 1 expression and tumor-infiltrating lymphocytes in glioblastoma. Neuro Oncol (2015) 17(8):1064-75. doi:10.1093/neuonc/nou307
    • (2015) Neuro Oncol , vol.17 , Issue.8 , pp. 1064-1075
    • Berghoff, A.S.1    Kiesel, B.2    Widhalm, G.3    Rajky, O.4    Ricken, G.5    Wöhrer, A.6
  • 58
    • 84897527381 scopus 로고    scopus 로고
    • Immune heterogeneity of glioblastoma subtypes: extrapolation from the cancer genome atlas
    • Doucette T, Rao G, Rao A, Shen L, Aldape K, Wei J, et al. Immune heterogeneity of glioblastoma subtypes: extrapolation from the cancer genome atlas. Cancer Immunol Res (2013) 1(2):112-22. doi:10.1158/2326-6066.CIR-13-0028
    • (2013) Cancer Immunol Res , vol.1 , Issue.2 , pp. 112-122
    • Doucette, T.1    Rao, G.2    Rao, A.3    Shen, L.4    Aldape, K.5    Wei, J.6
  • 59
    • 0034679560 scopus 로고    scopus 로고
    • Immunologic self-tolerance maintained by CD25(+)CD4(+) regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4
    • Takahashi T, Tagami T, Yamazaki S, Uede T, Shimizu J, Sakaguchi N, et al. Immunologic self-tolerance maintained by CD25(+)CD4(+) regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4. J Exp Med (2000) 192(2):303-10. doi:10.1084/jem.192.2.303
    • (2000) J Exp Med , vol.192 , Issue.2 , pp. 303-310
    • Takahashi, T.1    Tagami, T.2    Yamazaki, S.3    Uede, T.4    Shimizu, J.5    Sakaguchi, N.6
  • 60
    • 0034749035 scopus 로고    scopus 로고
    • Expression of Fas ligand by microglia: possible role in glioma immune evasion
    • Badie B, Schartner J, Prabakaran S, Paul J, Vorpahl J. Expression of Fas ligand by microglia: possible role in glioma immune evasion. J Neuroimmunol (2001) 120(1-2):19-24. doi:10.1016/S0165-5728(01)00361-7
    • (2001) J Neuroimmunol , vol.120 , Issue.1-2 , pp. 19-24
    • Badie, B.1    Schartner, J.2    Prabakaran, S.3    Paul, J.4    Vorpahl, J.5
  • 61
    • 0036570241 scopus 로고    scopus 로고
    • Identification of CD70-mediated apoptosis of immune effector cells as a novel immune escape pathway of human glioblastoma
    • Wischhusen J, Jung G, Radovanovic I, Beier C, Steinbach JP, Rimner A, et al. Identification of CD70-mediated apoptosis of immune effector cells as a novel immune escape pathway of human glioblastoma. Cancer Res (2002) 62(9):2592-9
    • (2002) Cancer Res , vol.62 , Issue.9 , pp. 2592-2599
    • Wischhusen, J.1    Jung, G.2    Radovanovic, I.3    Beier, C.4    Steinbach, J.P.5    Rimner, A.6
  • 62
    • 0030694234 scopus 로고    scopus 로고
    • The emerging role of CTLA-4 as an immune attenuator
    • Thompson CB, Allison JP. The emerging role of CTLA-4 as an immune attenuator. Immunity (1997) 7(4):445-50. doi:10.1016/S1074-7613(00)80366-0
    • (1997) Immunity , vol.7 , Issue.4 , pp. 445-450
    • Thompson, C.B.1    Allison, J.P.2
  • 63
    • 30744445427 scopus 로고    scopus 로고
    • Galectin-3 and galectin-1 bind distinct cell surface glycoprotein receptors to induce T cell death
    • Stillman BN, Hsu DK, Pang M, Brewer CF, Johnson P, Liu FT, et al. Galectin-3 and galectin-1 bind distinct cell surface glycoprotein receptors to induce T cell death. J Immunol (2006) 176(2):778-89. doi:10.4049/jimmunol.176.2.778
    • (2006) J Immunol , vol.176 , Issue.2 , pp. 778-789
    • Stillman, B.N.1    Hsu, D.K.2    Pang, M.3    Brewer, C.F.4    Johnson, P.5    Liu, F.T.6
  • 64
    • 0345734273 scopus 로고    scopus 로고
    • CD29 and CD7 mediate galectin-3-induced type II T-cell apoptosis
    • Fukumori T, Takenaka Y, Yoshii T, Kim HR, Hogan V, Inohara H, et al. CD29 and CD7 mediate galectin-3-induced type II T-cell apoptosis. Cancer Res (2003) 63(23):8302-11
    • (2003) Cancer Res , vol.63 , Issue.23 , pp. 8302-8311
    • Fukumori, T.1    Takenaka, Y.2    Yoshii, T.3    Kim, H.R.4    Hogan, V.5    Inohara, H.6
  • 65
    • 73949096430 scopus 로고    scopus 로고
    • Glioblastoma cancer-initiating cells inhibit T-cell proliferation and effector responses by the signal transducers and activators of transcription 3 pathway
    • Wei J, Barr J, Kong LY, Wang Y, Wu A, Sharma AK, et al. Glioblastoma cancer-initiating cells inhibit T-cell proliferation and effector responses by the signal transducers and activators of transcription 3 pathway. Mol Cancer Ther (2010) 9(1):67-78. doi:10.1158/1535-7163.MCT-09-0734
    • (2010) Mol Cancer Ther , vol.9 , Issue.1 , pp. 67-78
    • Wei, J.1    Barr, J.2    Kong, L.Y.3    Wang, Y.4    Wu, A.5    Sharma, A.K.6
  • 66
    • 77950221879 scopus 로고    scopus 로고
    • Transcriptional profiles of CD133+ and CD133-glioblastoma-derived cancer stem cell lines suggest different cells of origin
    • Lottaz C, Beier D, Meyer K, Kumar P, Hermann A, Schwarz J, et al. Transcriptional profiles of CD133+ and CD133-glioblastoma-derived cancer stem cell lines suggest different cells of origin. Cancer Res (2010) 70(5):2030-40. doi:10.1158/0008-5472.CAN-09-1707
    • (2010) Cancer Res , vol.70 , Issue.5 , pp. 2030-2040
    • Lottaz, C.1    Beier, D.2    Meyer, K.3    Kumar, P.4    Hermann, A.5    Schwarz, J.6
  • 67
    • 28544444135 scopus 로고    scopus 로고
    • Human leukocyte antigen and antigen processing machinery component defects in astrocytic tumors
    • Facoetti A, Nano R, Zelini P, Morbini P, Benericetti E, Ceroni M, et al. Human leukocyte antigen and antigen processing machinery component defects in astrocytic tumors. Clin Cancer Res (2005) 11(23):8304-11. doi:10.1158/1078-0432.CCR-04-2588
    • (2005) Clin Cancer Res , vol.11 , Issue.23 , pp. 8304-8311
    • Facoetti, A.1    Nano, R.2    Zelini, P.3    Morbini, P.4    Benericetti, E.5    Ceroni, M.6
  • 68
    • 0035879509 scopus 로고    scopus 로고
    • Role of microglia in glioma biology
    • Badie B, Schartner J. Role of microglia in glioma biology. Microsc Res Tech (2001) 54(2):106-13. doi:10.1002/jemt.1125
    • (2001) Microsc Res Tech , vol.54 , Issue.2 , pp. 106-113
    • Badie, B.1    Schartner, J.2
  • 69
    • 63849335831 scopus 로고    scopus 로고
    • Flow cytometry and in vitro analysis of human glioma-associated macrophages Laboratory investigation
    • Parney IF, Waldron JS, Parsa AT. Flow cytometry and in vitro analysis of human glioma-associated macrophages. Laboratory investigation. J Neurosurg (2009) 110(3):572-82. doi:10.3171/2008.7.JNS08475
    • (2009) J Neurosurg , vol.110 , Issue.3 , pp. 572-582
    • Parney, I.F.1    Waldron, J.S.2    Parsa, A.T.3
  • 70
    • 84926372398 scopus 로고    scopus 로고
    • Tumor-associated macrophages in glioblastoma multiforme-a suitable target for somatostatin receptor-based imaging and therapy?
    • Lapa C, Linsenmann T, Lückerath K, Samnick S, Herrmann K, Stoffer C, et al. Tumor-associated macrophages in glioblastoma multiforme-a suitable target for somatostatin receptor-based imaging and therapy? PLoS One (2015) 10(3):e0122269. doi:10.1371/journal.pone.0122269
    • (2015) PLoS One , vol.10 , Issue.3
    • Lapa, C.1    Linsenmann, T.2    Lückerath, K.3    Samnick, S.4    Herrmann, K.5    Stoffer, C.6
  • 71
    • 84857883847 scopus 로고    scopus 로고
    • Macrophage plasticity and polarization: in vivo veritas
    • Sica A, Mantovani A. Macrophage plasticity and polarization: in vivo veritas. J Clin Invest (2012) 122(3):787-95. doi:10.1172/JCI59643
    • (2012) J Clin Invest , vol.122 , Issue.3 , pp. 787-795
    • Sica, A.1    Mantovani, A.2
  • 73
    • 34648831673 scopus 로고    scopus 로고
    • Application of the ELISPOT method for comparative analysis of interleukin (IL)-6 and IL-10 secretion in peripheral blood of patients with astroglial tumors
    • Samaras V, Piperi C, Korkolopoulou P, Zisakis A, Levidou G, Themistocleous MS, et al. Application of the ELISPOT method for comparative analysis of interleukin (IL)-6 and IL-10 secretion in peripheral blood of patients with astroglial tumors. Mol Cell Biochem (2007) 304(1-2):343-51. doi:10.1007/s11010-007-9517-3
    • (2007) Mol Cell Biochem , vol.304 , Issue.1-2 , pp. 343-351
    • Samaras, V.1    Piperi, C.2    Korkolopoulou, P.3    Zisakis, A.4    Levidou, G.5    Themistocleous, M.S.6
  • 74
    • 84879604170 scopus 로고    scopus 로고
    • Molecular definition of the pro-tumorigenic phenotype of glioma-activated microglia
    • Ellert-Miklaszewska A, Dabrowski M, Lipko M, Sliwa M, Maleszewska M, Kaminska B. Molecular definition of the pro-tumorigenic phenotype of glioma-activated microglia. Glia (2013) 61(7):1178-90. doi:10.1002/glia.22510
    • (2013) Glia , vol.61 , Issue.7 , pp. 1178-1190
    • Ellert-Miklaszewska, A.1    Dabrowski, M.2    Lipko, M.3    Sliwa, M.4    Maleszewska, M.5    Kaminska, B.6
  • 75
    • 78049270536 scopus 로고    scopus 로고
    • Glioma cancer stem cells induce immunosuppressive macrophages/microglia
    • Wu A, Wei J, Kong LY, Wang Y, Priebe W, Qiao W, et al. Glioma cancer stem cells induce immunosuppressive macrophages/microglia. Neuro Oncol (2010) 12(11):1113-25. doi:10.1093/neuonc/noq082
    • (2010) Neuro Oncol , vol.12 , Issue.11 , pp. 1113-1125
    • Wu, A.1    Wei, J.2    Kong, L.Y.3    Wang, Y.4    Priebe, W.5    Qiao, W.6
  • 76
    • 84923068676 scopus 로고    scopus 로고
    • Periostin secreted by glioblastoma stem cells recruits M2 tumour-associated macrophages and promotes malignant growth
    • Zhou W, Ke SQ, Huang Z, Flavahan W, Fang X, Paul J, et al. Periostin secreted by glioblastoma stem cells recruits M2 tumour-associated macrophages and promotes malignant growth. Nat Cell Biol (2015) 17(2):170-82. doi:10.1038/ncb3090
    • (2015) Nat Cell Biol , vol.17 , Issue.2 , pp. 170-182
    • Zhou, W.1    Ke, S.Q.2    Huang, Z.3    Flavahan, W.4    Fang, X.5    Paul, J.6
  • 77
    • 84962087225 scopus 로고    scopus 로고
    • Tumour-processed osteopontin and lactadherin drive the protumorigenic reprogramming of microglia and glioma progression
    • Ellert-Miklaszewska A, Wisniewski P, Kijewska M, Gajdanowicz P, Pszczolkowska D, Przanowski P, et al. Tumour-processed osteopontin and lactadherin drive the protumorigenic reprogramming of microglia and glioma progression. Oncogene (2016) 35(50):6366-77. doi:10.1038/onc.2016.55
    • (2016) Oncogene , vol.35 , Issue.50 , pp. 6366-6377
    • Ellert-Miklaszewska, A.1    Wisniewski, P.2    Kijewska, M.3    Gajdanowicz, P.4    Pszczolkowska, D.5    Przanowski, P.6
  • 78
    • 84975276172 scopus 로고    scopus 로고
    • Glioblastoma-infiltrated innate immune cells resemble M0 macrophage phenotype
    • Gabrusiewicz K, Rodriguez B, Wei J, Hashimoto Y, Healy LM, Maiti SN, et al. Glioblastoma-infiltrated innate immune cells resemble M0 macrophage phenotype. JCI Insight (2016) 1(2):e85841. doi:10.1172/jci.insight.85841
    • (2016) JCI Insight , vol.1 , Issue.2
    • Gabrusiewicz, K.1    Rodriguez, B.2    Wei, J.3    Hashimoto, Y.4    Healy, L.M.5    Maiti, S.N.6
  • 79
    • 79960003585 scopus 로고    scopus 로고
    • Myeloid-derived suppressor cell accumulation and function in patients with newly diagnosed glioblastoma
    • Raychaudhuri B, Rayman P, Ireland J, Ko J, Rini B, Borden EC, et al. Myeloid-derived suppressor cell accumulation and function in patients with newly diagnosed glioblastoma. Neuro Oncol (2011) 13(6):591-9. doi:10.1093/neuonc/nor042
    • (2011) Neuro Oncol , vol.13 , Issue.6 , pp. 591-599
    • Raychaudhuri, B.1    Rayman, P.2    Ireland, J.3    Ko, J.4    Rini, B.5    Borden, E.C.6
  • 81
    • 84982845015 scopus 로고    scopus 로고
    • Cancer stem cell-secreted macrophage migration inhibitory factor stimulates myeloid derived suppressor cell function and facilitates glioblastoma immune evasion
    • Otvos B, Silver DJ, Mulkearns-Hubert EE, Alvarado AG, Turaga SM, Sorensen MD, et al. Cancer stem cell-secreted macrophage migration inhibitory factor stimulates myeloid derived suppressor cell function and facilitates glioblastoma immune evasion. Stem Cells (2016) 34(8):2026-39. doi:10.1002/stem.2393
    • (2016) Stem Cells , vol.34 , Issue.8 , pp. 2026-2039
    • Otvos, B.1    Silver, D.J.2    Mulkearns-Hubert, E.E.3    Alvarado, A.G.4    Turaga, S.M.5    Sorensen, M.D.6
  • 82
    • 85010469830 scopus 로고    scopus 로고
    • Systemic T cells immunosuppression of glioma stem cell-derived exosomes is mediated by monocytic myeloid-derived suppressor cells
    • Domenis R, Cesselli D, Toffoletto B, Bourkoula E, Caponnetto F, Manini I, et al. Systemic T cells immunosuppression of glioma stem cell-derived exosomes is mediated by monocytic myeloid-derived suppressor cells. PLoS One (2017) 12(1):e0169932. doi:10.1371/journal.pone.0169932
    • (2017) PLoS One , vol.12 , Issue.1
    • Domenis, R.1    Cesselli, D.2    Toffoletto, B.3    Bourkoula, E.4    Caponnetto, F.5    Manini, I.6
  • 83
    • 0033972180 scopus 로고    scopus 로고
    • The HLA crossroad in tumor immunology
    • Algarra I, Cabrera T, Garrido F. The HLA crossroad in tumor immunology. Hum Immunol (2000) 61(1):65-73. doi:10.1016/S0198-8859(99)00156-1
    • (2000) Hum Immunol , vol.61 , Issue.1 , pp. 65-73
    • Algarra, I.1    Cabrera, T.2    Garrido, F.3
  • 84
    • 84991392300 scopus 로고    scopus 로고
    • IDH mutant gliomas escape natural killer cell immune surveillance by downregulation of NKG2D ligand expression
    • Zhang X, Rao A, Sette P, Deibert C, Pomerantz A, Kim WJ, et al. IDH mutant gliomas escape natural killer cell immune surveillance by downregulation of NKG2D ligand expression. Neuro Oncol (2016) 18(10):1402-12. doi:10.1093/neuonc/now061
    • (2016) Neuro Oncol , vol.18 , Issue.10 , pp. 1402-1412
    • Zhang, X.1    Rao, A.2    Sette, P.3    Deibert, C.4    Pomerantz, A.5    Kim, W.J.6
  • 85
    • 84855684581 scopus 로고    scopus 로고
    • Human glioblastoma stem-like cells are more sensitive to allogeneic NK and T cell-mediated killing compared with serum-cultured glioblastoma cells
    • Avril T, Vauleon E, Hamlat A, Saikali S, Etcheverry A, Delmas C, et al. Human glioblastoma stem-like cells are more sensitive to allogeneic NK and T cell-mediated killing compared with serum-cultured glioblastoma cells. Brain Pathol (2012) 22(2):159-74. doi:10.1111/j.1750-3639.2011.00515.x
    • (2012) Brain Pathol , vol.22 , Issue.2 , pp. 159-174
    • Avril, T.1    Vauleon, E.2    Hamlat, A.3    Saikali, S.4    Etcheverry, A.5    Delmas, C.6
  • 86
    • 84923183950 scopus 로고    scopus 로고
    • Anti-PD-1-targeted therapies focusing on lymphatic malignancies: biological rationale, clinical challenges and opportunities
    • Kedmi M, Avigdor A, Nagler A. Anti-PD-1-targeted therapies focusing on lymphatic malignancies: biological rationale, clinical challenges and opportunities. Acta Haematol (2015) 133(2):129-35. doi:10.1159/000362151
    • (2015) Acta Haematol , vol.133 , Issue.2 , pp. 129-135
    • Kedmi, M.1    Avigdor, A.2    Nagler, A.3
  • 87
    • 84943194758 scopus 로고    scopus 로고
    • The PD-1/B7-H1 pathway modulates the natural killer cells versus mouse glioma stem cells
    • Huang BY, Zhan YP, Zong WJ, Yu CJ, Li JF, Qu YM, et al. The PD-1/B7-H1 pathway modulates the natural killer cells versus mouse glioma stem cells. PLoS One (2015) 10(8):e0134715. doi:10.1371/journal.pone.0134715
    • (2015) PLoS One , vol.10 , Issue.8
    • Huang, B.Y.1    Zhan, Y.P.2    Zong, W.J.3    Yu, C.J.4    Li, J.F.5    Qu, Y.M.6
  • 88
    • 85016924431 scopus 로고    scopus 로고
    • Advances in immunotherapy for glioblastoma multiforme
    • Huang B, Zhang H, Gu L, Ye B, Jian Z, Stary C, et al. Advances in immunotherapy for glioblastoma multiforme. J Immunol Res (2017) 2017:3597613. doi:10.1155/2017/3597613
    • (2017) J Immunol Res , vol.2017
    • Huang, B.1    Zhang, H.2    Gu, L.3    Ye, B.4    Jian, Z.5    Stary, C.6
  • 89
    • 17644370329 scopus 로고    scopus 로고
    • Cell biology of antigen processing in vitro and in vivo
    • Trombetta ES, Mellman I. Cell biology of antigen processing in vitro and in vivo. Annu Rev Immunol (2005) 23:975-1028. doi:10.1146/annurev.immunol.22.012703.104538
    • (2005) Annu Rev Immunol , vol.23 , pp. 975-1028
    • Trombetta, E.S.1    Mellman, I.2
  • 91
    • 0034613767 scopus 로고    scopus 로고
    • Induction of interleukin 10-producing, nonproliferating CD4(+) T cells with regulatory properties by repetitive stimulation with allogeneic immature human dendritic cells
    • Jonuleit H, Schmitt E, Schuler G, Knop J, Enk AH. Induction of interleukin 10-producing, nonproliferating CD4(+) T cells with regulatory properties by repetitive stimulation with allogeneic immature human dendritic cells. J Exp Med (2000) 192(9):1213-22. doi:10.1084/jem.192.9.1213
    • (2000) J Exp Med , vol.192 , Issue.9 , pp. 1213-1222
    • Jonuleit, H.1    Schmitt, E.2    Schuler, G.3    Knop, J.4    Enk, A.H.5
  • 92
    • 70449368149 scopus 로고    scopus 로고
    • Induction of Treg by monocyte-derived DC modulated by vitamin D3 or dexamethasone: differential role for PD-L1
    • Unger WW, Laban S, Kleijwegt FS, van der Slik AR, Roep BO. Induction of Treg by monocyte-derived DC modulated by vitamin D3 or dexamethasone: differential role for PD-L1. Eur J Immunol (2009) 39(11):3147-59. doi:10.1002/eji.200839103
    • (2009) Eur J Immunol , vol.39 , Issue.11 , pp. 3147-3159
    • Unger, W.W.1    Laban, S.2    Kleijwegt, F.S.3    van der Slik, A.R.4    Roep, B.O.5
  • 93
    • 70449700301 scopus 로고    scopus 로고
    • Dendritic cell vaccines for cancer stem cells
    • Pellegatta S, Finocchiaro G. Dendritic cell vaccines for cancer stem cells. Methods Mol Biol (2009) 568:233-47. doi:10.1007/978-1-59745-280-9_15
    • (2009) Methods Mol Biol , vol.568 , pp. 233-247
    • Pellegatta, S.1    Finocchiaro, G.2


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