-
2
-
-
34547122001
-
The 2007 WHO classifcation of tumours of the central nervous system
-
Louis DN, Ohgaki H, Wiestler OD, Cavenee WK, Burger PC, Jouvet A, Scheithauer BW, Kleihues P. The 2007 WHO classifcation of tumours of the central nervous system. Acta Neuropathol. 2007;114:97–109.
-
(2007)
Acta Neuropathol
, vol.114
, pp. 97-109
-
-
Louis, D.N.1
Ohgaki, H.2
Wiestler, O.D.3
Cavenee, W.K.4
Burger, P.C.5
Jouvet, A.6
Scheithauer, B.W.7
Kleihues, P.8
-
3
-
-
35949002429
-
Malignant astrocytic glio-ma: Genetics, biology, and paths to treatment
-
Furnari FB, Fenton T, Bachoo RM, Mukasa A, Stommel JM, Stegh A, Hahn WC, Ligon KL, Louis DN, Brennan C, Chin L, DePinho RA, Cavenee WK. Malignant astrocytic glio-ma: genetics, biology, and paths to treatment. Genes Dev. 2007;21:2683–710.
-
(2007)
Genes Dev
, vol.21
, pp. 2683-2710
-
-
Furnari, F.B.1
Fenton, T.2
Bachoo, R.M.3
Mukasa, A.4
Stommel, J.M.5
Stegh, A.6
Hahn, W.C.7
Ligon, K.L.8
Louis, D.N.9
Brennan, C.10
Chin, L.11
Depinho, R.A.12
Cavenee, W.K.13
-
4
-
-
84859847164
-
Emerging insights into the molecular and cellular basis of glioblastoma
-
Dunn GP, Rinne ML, Wykosky J, Genovese G, Quayle SN, Dunn IF, Agarwalla PK, Chheda MG, Campos B, Wang A, Brennan C, Ligon KL, Furnari F, Cavenee WK, Depinho RA, Chin L, Hahn WC. Emerging insights into the molecular and cellular basis of glioblastoma. Genes Dev. 2012;26:756–84.
-
(2012)
Genes Dev
, vol.26
, pp. 756-784
-
-
Dunn, G.P.1
Rinne, M.L.2
Wykosky, J.3
Genovese, G.4
Quayle, S.N.5
Dunn, I.F.6
Agarwalla, P.K.7
Chheda, M.G.8
Campos, B.9
Wang, A.10
Brennan, C.11
Ligon, K.L.12
Furnari, F.13
Cavenee, W.K.14
Depinho, R.A.15
Chin, L.16
Hahn, W.C.17
-
5
-
-
54549108740
-
Comprehensive genomic characterization de-fnes human glioblastoma genes and core pathways
-
Cancer Genome Atlas Research Network. Comprehensive genomic characterization de-fnes human glioblastoma genes and core pathways. Nature. 2008;455(7216):1061–8.
-
(2008)
Nature
, vol.455
, Issue.7216
, pp. 1061-1068
-
-
-
6
-
-
33644820339
-
Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis
-
Phillips HS, Kharbanda S, Chen R, Forrest WF, Soriano RH, Wu TD, Misra A, Nigro JM, Colman H, Soroceanu L, Williams PM, Mo-drusan Z, Feuerstein BG, Aldape K. Molecular subclasses of high-grade glioma predict prognosis, delineate a pattern of disease progression, and resemble stages in neurogenesis. Cancer Cell. 2006;9:157–73.
-
(2006)
Cancer Cell
, vol.9
, pp. 157-173
-
-
Phillips, H.S.1
Kharbanda, S.2
Chen, R.3
Forrest, W.F.4
Soriano, R.H.5
Wu, T.D.6
Misra, A.7
Nigro, J.M.8
Colman, H.9
Soroceanu, L.10
Williams, P.M.11
Mo-Drusan, Z.12
Feuerstein, B.G.13
Aldape, K.14
-
7
-
-
52949127312
-
An integrated genomic analysis of human glioblastoma mul- tiforme
-
Parsons DW, Jones S, Zhang X, Lin JC, Leary RJ, Angenendt P, Mankoo P, Carter H, Siu IM, Gallia GL, Olivi A, McLendon R, Ra-sheed BA, Keir S, Nikolskaya T, Nikolsky Y, Busam DA, Tekleab H, Diaz LA Jr, Hartigan J, Smith DR, Strausberg RL, Marie SK, Shinjo SM, Yan H, Riggins GJ, Bigner DD, Karchin R, Papadopoulos N, Parmigiani G, Vogelstein B, Velculescu VE, Kinzler KW. An integrated genomic analysis of human glioblastoma mul- tiforme. Science. 2008;321:1807–12.
-
(2008)
Science
, vol.321
, pp. 1807-1812
-
-
Parsons, D.W.1
Jones, S.2
Zhang, X.3
Lin, J.C.4
Leary, R.J.5
Angenendt, P.6
Mankoo, P.7
Carter, H.8
Siu, I.M.9
Gallia, G.L.10
Olivi, A.11
McLendon, R.12
Ra-Sheed, B.A.13
Keir, S.14
Nikolskaya, T.15
Nikolsky, Y.16
Busam, D.A.17
Tekleab, H.18
Diaz, L.A.19
Hartigan, J.20
Smith, D.R.21
Strausberg, R.L.22
Marie, S.K.23
Shinjo, S.M.24
Yan, H.25
Riggins, G.J.26
Bigner, D.D.27
Karchin, R.28
Papadopoulos, N.29
Parmigiani, G.30
Vogelstein, B.31
Velculescu, V.E.32
Kinzler, K.W.33
more..
-
8
-
-
73649123907
-
Cancer Genome Atlas Research Network. Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDG- FRA, IDH1, EGFR, and NF1
-
Verhaak RG, Hoadley KA, Purdom E, Wang V, Qi Y, Wilkerson MD, Miller CR, Ding L, Golub T, Mesirov JP, Alexe G, Lawrence M, O’Kelly M, Tamayo P, Weir BA, Gabriel S, Winckler W, Gupta S, Jakkula L, Feiler HS, Hodgson JG, James CD, Sarkaria JN, Brennan C, Kahn A, Spellman PT, Wilson RK, Speed TP, Gray JW, Meyerson M, Getz G, Perou CM, Hayes DN; Cancer Genome Atlas Research Network. Integrated genomic analysis identifies clinically relevant subtypes of glioblastoma characterized by abnormalities in PDG- FRA, IDH1, EGFR, and NF1. Cancer Cell. 2010;17(1):98–110.
-
(2010)
Cancer Cell
, vol.17
, Issue.1
, pp. 98-110
-
-
Verhaak, R.G.1
Hoadley, K.A.2
Purdom, E.3
Wang, V.4
Qi, Y.5
Wilkerson, M.D.6
Miller, C.R.7
Ding, L.8
Golub, T.9
Mesirov, J.P.10
Alexe, G.11
Lawrence, M.12
O’kelly, M.13
Tamayo, P.14
Weir, B.A.15
Gabriel, S.16
Winckler, W.17
Gupta, S.18
Jakkula, L.19
Feiler, H.S.20
Hodgson, J.G.21
James, C.D.22
Sarkaria, J.N.23
Brennan, C.24
Kahn, A.25
Spellman, P.T.26
Wilson, R.K.27
Speed, T.P.28
Gray, J.W.29
Meyerson, M.30
Getz, G.31
Perou, C.M.32
Hayes, D.N.33
more..
-
9
-
-
38149129457
-
A transcriptome database for astrocytes, neurons, and oligo-dendrocytes: A new resource for understanding brain development and function
-
Cahoy JD, Emery B, Kaushal A, Foo LC, Zamanian JL, Christopherson KS, Xing Y, Lubischer JL, Krieg PA, Krupenko SA, Thompson WJ, Barres BA. A transcriptome database for astrocytes, neurons, and oligo-dendrocytes: a new resource for understanding brain development and function. J Neurosci. 2008;28:264–78.
-
(2008)
J Neurosci
, vol.28
, pp. 264-278
-
-
Cahoy, J.D.1
Emery, B.2
Kaushal, A.3
Foo, L.C.4
Zamanian, J.L.5
Christopherson, K.S.6
Xing, Y.7
Lubischer, J.L.8
Krieg, P.A.9
Krupenko, S.A.10
Thompson, W.J.11
Barres, B.A.12
-
10
-
-
79955514336
-
A developmental taxonomy of glioblas-toma defned and maintained by MicroRNAs
-
Kim TM, Huang W, Park R, Park PJ, Johnson MD. A developmental taxonomy of glioblas-toma defned and maintained by MicroRNAs. Cancer Res. 2011;71:3387–99.
-
(2011)
Cancer Res
, vol.71
, pp. 3387-3399
-
-
Kim, T.M.1
Huang, W.2
Park, R.3
Park, P.J.4
Johnson, M.D.5
-
11
-
-
77952108366
-
Cancer Genome Atlas Research Network. Identification of a CpG island methyl-ator phenotype that defines a distinct subgroup of glioma
-
Noushmehr H, Weisenberger DJ, Diefes K, Phillips HS, Pujara K, Berman BP, Pan F, Pel-loski CE, Sulman EP, Bhat KP, Verhaak RG, Hoadley KA, Hayes DN, Perou CM, Schmidt HK, Ding L, Wilson RK, Van Den Berg D, Shen H, Bengtsson H, Neuvial P, Cope LM, Buckley J, Herman JG, Baylin SB, Laird PW, Aldape K; Cancer Genome Atlas Research Network. Identification of a CpG island methyl-ator phenotype that defines a distinct subgroup of glioma. Cancer Cell. 2010;17(5):510–22.
-
(2010)
Cancer Cell
, vol.17
, Issue.5
, pp. 510-522
-
-
Noushmehr, H.1
Weisenberger, D.J.2
Diefes, K.3
Phillips, H.S.4
Pujara, K.5
Berman, B.P.6
Pan, F.7
Pel-Loski, C.E.8
Sulman, E.P.9
Bhat, K.P.10
Verhaak, R.G.11
Hoadley, K.A.12
Hayes, D.N.13
Perou, C.M.14
Schmidt, H.K.15
Ding, L.16
Wilson, R.K.17
Van Den Berg, D.18
Shen, H.19
Bengtsson, H.20
Neuvial, P.21
Cope, L.M.22
Buckley, J.23
Herman, J.G.24
Baylin, S.B.25
Laird, P.W.26
Aldape, K.27
more..
-
12
-
-
84879764400
-
A survey of intra-genic breakpoints in glioblastoma identifies a distinct subset associated with poor survival
-
Zheng S, Fu J, Vegesna R, Mao Y, Heathcock LE, Torres-Garcia W, Ezhilarasan R, Wang S, McKenna A, Chin L, Brennan CW, Yung WK, Weinstein JN, Aldape K., Sulman EP, Chen K, Koul D, Verhaak RG. A survey of intra-genic breakpoints in glioblastoma identifies a distinct subset associated with poor survival. Genes Dev. 2013;27:1462–72.
-
(2013)
Genes Dev
, vol.27
, pp. 1462-1472
-
-
Zheng, S.1
Fu, J.2
Vegesna, R.3
Mao, Y.4
Heathcock, L.E.5
Torres-Garcia, W.6
Ezhilarasan, R.7
Wang, S.8
McKenna, A.9
Chin, L.10
Brennan, C.W.11
Yung, W.K.12
Weinstein, J.N.13
Aldape, K.14
Sulman, E.P.15
Chen, K.16
Koul, D.17
Verhaak, R.G.18
-
13
-
-
33750313208
-
Mwahl GM. Cancer stem cells–perspectives on current status and future directions: AACR Workshop on cancer stem cells
-
Clarke MF, Dick JE, Dirks PB, Eaves CJ, Ja-mieson CH, Jones DL, Visvader J, Weissman IL, Mwahl GM. Cancer stem cells–perspectives on current status and future directions: AACR Workshop on cancer stem cells. Cancer Res. 2006;66(19):9339–44.
-
(2006)
Cancer Res
, vol.66
, Issue.19
, pp. 9339-9344
-
-
Clarke, M.F.1
Dick, J.E.2
Dirks, P.B.3
Eaves, C.J.4
Ja-Mieson, C.H.5
Jones, D.L.6
Visvader, J.7
Weissman, I.L.8
-
14
-
-
9244241576
-
Identification of human brain tumour initiating cells
-
Singh SK, Hawkins C, Clarke ID, Squire JA, Bayani J, Hide T, Henkelman RM, Cusimano MD, Dirks PB. Identification of human brain tumour initiating cells. Nature. 2004;432:396–401.
-
(2004)
Nature
, vol.432
, pp. 396-401
-
-
Singh, S.K.1
Hawkins, C.2
Clarke, I.D.3
Squire, J.A.4
Bayani, J.5
Hide, T.6
Henkelman, R.M.7
Cusimano, M.D.8
Dirks, P.B.9
-
15
-
-
33845317573
-
Glioma stem cells promote radiore-sistance by preferential activation of the DNA damage response
-
Bao S, Wu Q, McLendon RE, Hao Y, Shi Q, Hjelmeland AB, Dewhirst MW, Bigner DD, Rich JN. Glioma stem cells promote radiore-sistance by preferential activation of the DNA damage response. Nature. 2006;444:756–60.
-
(2006)
Nature
, vol.444
, pp. 756-760
-
-
Bao, S.1
Wu, Q.2
McLendon, R.E.3
Hao, Y.4
Shi, Q.5
Hjelmeland, A.B.6
Dewhirst, M.W.7
Bigner, D.D.8
Rich, J.N.9
-
16
-
-
60849117508
-
PTEN/PI3K/Akt pathway regulates the side population phenotype and ABCG2 activity in glioma tumor stem-like cells
-
Bleau AM, Hambardzumyan D, Ozawa T, Fomchenko EI, Huse JT, Brennan CW, Hol-land EC. PTEN/PI3K/Akt pathway regulates the side population phenotype and ABCG2 activity in glioma tumor stem-like cells. Cell Stem Cell. 2009;4:226–35.
-
(2009)
Cell Stem Cell
, vol.4
, pp. 226-235
-
-
Bleau, A.M.1
Hambardzumyan, D.2
Ozawa, T.3
Fomchenko, E.I.4
Huse, J.T.5
Brennan, C.W.6
Hol-Land, E.C.7
-
17
-
-
34249332411
-
CD133(+) and CD133(-) glioblastoma-derived cancer stem cells show differential growth characteristics and molecular profles
-
Beier D, Hau P, Proescholdt M, Lohmeier A, Wischhusen J, Oefner PJ, Aigner L, Brawa-nski A, Bogdahn U, Beier CP. CD133(+) and CD133(-) glioblastoma-derived cancer stem cells show differential growth characteristics and molecular profles. Cancer Res. 2007;67:4010–5.
-
(2007)
Cancer Res
, vol.67
, pp. 4010-4015
-
-
Beier, D.1
Hau, P.2
Proescholdt, M.3
Lohmeier, A.4
Wischhusen, J.5
Oefner, P.J.6
Aigner, L.7
Brawa-Nski, A.8
Bogdahn, U.9
Beier, C.P.10
-
18
-
-
48749114753
-
Clinical and biological implications of CD133-positive and CD133-negative cells in glioblastomas
-
Joo KM, Kim SY, Jin X, Song SY, Kong DS, Lee JI, Jeon JW, Kim MH, Kang BG, Jung Y, Jin J, Hong SC, Park WY, Lee DS, Kim H, Nam DH. Clinical and biological implications of CD133-positive and CD133-negative cells in glioblastomas. Lab Invest. 2008;88:808–15.
-
(2008)
Lab Invest
, vol.88
, pp. 808-815
-
-
Joo, K.M.1
Kim, S.Y.2
Jin, X.3
Song, S.Y.4
Kong, D.S.5
Lee, J.I.6
Jeon, J.W.7
Kim, M.H.8
Kang, B.G.9
Jung, Y.10
Jin, J.11
Hong, S.C.12
Park, W.Y.13
Lee, D.S.14
Kim, H.15
Nam, D.H.16
-
19
-
-
77950502115
-
A hierarchy of self-renewing tumor-initiating cell types in glioblastoma
-
Chen R, Nishimura MC, Bumbaca SM, Khar-banda S, Forrest WF, Kasman IM, Greve JM, Soriano RH, Gilmour LL, Rivers CS, Modru-san Z, Nacu S, Guerrero S, Edgar KA, Wallin JJ, Lamszus K, Westphal M, Heim S, James CD, VandenBerg SR, Costello JF, Moore-feld S, Cowdrey CJ, Prados M, Phillips HS. A hierarchy of self-renewing tumor-initiating cell types in glioblastoma. Cancer Cell. 2010;17:362–75.
-
(2010)
Cancer Cell
, vol.17
, pp. 362-375
-
-
Chen, R.1
Nishimura, M.C.2
Bumbaca, S.M.3
Khar-Banda, S.4
Forrest, W.F.5
Kasman, I.M.6
Greve, J.M.7
Soriano, R.H.8
Gilmour, L.L.9
Rivers, C.S.10
Modru-San, Z.11
Nacu, S.12
Guerrero, S.13
Edgar, K.A.14
Wallin, J.J.15
Lamszus, K.16
Westphal, M.17
Heim, S.18
James, C.D.19
Vandenberg, S.R.20
Costello, J.F.21
Moore-Feld, S.22
Cowdrey, C.J.23
Prados, M.24
Phillips, H.S.25
more..
-
20
-
-
78649986150
-
TGF-beta receptor inhibitors target the CD44(high)/Id1(high) glioma-initiating cell population in human glioblastoma
-
Anido J, Saez-Borderias A, Gonzalez-Junca A, Rodon L, Folch G, Carmona MA, Prieto-San-chez RM, Barba I, Martinez-Saez E, Prudkin L, Cuartas I, Raventos C, Martinez-Ricarte F, Poca MA, Garcia-Dorado D, Lahn MM, Yin-gling JM, Rodon J, Sahuquillo J, Baselga J, Seoane J. TGF-beta receptor inhibitors target the CD44(high)/Id1(high) glioma-initiating cell population in human glioblastoma. Cancer Cell. 2010;18:655–68.
-
(2010)
Cancer Cell
, vol.18
, pp. 655-668
-
-
Anido, J.1
Saez-Borderias, A.2
Gonzalez-Junca, A.3
Rodon, L.4
Folch, G.5
Carmona, M.A.6
Prieto-San-chez, R.M.7
Barba, I.8
Martinez-Saez, E.9
Prudkin, L.10
Cuartas, I.11
Raventos, C.12
Martinez-Ricarte, F.13
Poca, M.A.14
Garcia-Dorado, D.15
Lahn, M.M.16
Yin-Gling, J.M.17
Rodon, J.18
Sahuquillo, J.19
Baselga, J.20
Seoane, J.21
more..
-
21
-
-
84869878282
-
Dedifferentiation of neurons and astrocytes by oncogenes can induce gliomas in mice
-
Friedmann-Morvinski D, Bushong EA, Ke E, Soda Y, Marumoto T, Singer O, Ellisman MH, Verma IM. Dedifferentiation of neurons and astrocytes by oncogenes can induce gliomas in mice. Science. 2012;338:1080–4.
-
(2012)
Science
, vol.338
, pp. 1080-1084
-
-
Friedmann-Morvinski, D.1
Bushong, E.A.2
Ke, E.3
Soda, Y.4
Marumoto, T.5
Singer, O.6
Ellisman, M.H.7
Verma, I.M.8
-
22
-
-
68549085529
-
Establishment of a normal hematopoietic and leukemia stem cell hierarchy
-
Chao MP, Seita J, Weissman IL. Establishment of a normal hematopoietic and leukemia stem cell hierarchy. Cold Spring Harb Symp Quant Biol. 2008;73:439–49.
-
(2008)
Cold Spring Harb Symp Quant Biol
, vol.73
, pp. 439-449
-
-
Chao, M.P.1
Seita, J.2
Weissman, I.L.3
-
23
-
-
84865203983
-
A restricted cell population propagates glioblastoma growth after chemotherapy
-
Chen J, Li Y, Yu TS, McKay RM, Burns DK, Kernie SG, Parada LF. A restricted cell population propagates glioblastoma growth after chemotherapy. Nature. 2012;488:522–6.
-
(2012)
Nature
, vol.488
, pp. 522-526
-
-
Chen, J.1
Li, Y.2
Yu, T.S.3
McKay, R.M.4
Burns, D.K.5
Kernie, S.G.6
Parada, L.F.7
-
24
-
-
78751676408
-
Cells of origin in cancer
-
Visvader JE. Cells of origin in cancer. Nature. 2011;469:314–22.
-
(2011)
Nature
, vol.469
, pp. 314-322
-
-
Visvader, J.E.1
-
25
-
-
23644443053
-
Early inac-tivation of p53 tumor suppressor gene cooperating with NF1 loss induces malignant astro-cytoma
-
Zhu Y, Guignard F, Zhao D, Liu L, Burns DK, Mason RP, Messing A, Parada LF. Early inac-tivation of p53 tumor suppressor gene cooperating with NF1 loss induces malignant astro-cytoma. Cancer Cell. 2005;8:119–30.
-
(2005)
Cancer Cell
, vol.8
, pp. 119-130
-
-
Zhu, Y.1
Guignard, F.2
Zhao, D.3
Liu, L.4
Burns, D.K.5
Mason, R.P.6
Messing, A.7
Parada, L.F.8
-
26
-
-
44849089702
-
Pten haploinsuffciency accelerates formation of high-grade astrocytomas
-
Kwon CH, Zhao D, Chen J, Alcantara S, Li Y, Burns DK, Mason RP, Lee EY, Wu H, Para-da LF. Pten haploinsuffciency accelerates formation of high-grade astrocytomas. Cancer Res. 2008;68:3286–94.
-
(2008)
Cancer Res
, vol.68
, pp. 3286-3294
-
-
Kwon, C.H.1
Zhao, D.2
Chen, J.3
Alcantara, S.4
Li, Y.5
Burns, D.K.6
Mason, R.P.7
Lee, E.Y.8
Wu, H.9
Para-Da, L.F.10
-
27
-
-
57849109837
-
Malignant astrocytomas originate from neural stem/progenitor cells in a somatic tumor suppressor mouse model
-
Alcantara Llaguno S, Chen J, Kwon CH, Jackson EL, Li Y, Burns DK, Alvarez-Buylla A, Parada LF. Malignant astrocytomas originate from neural stem/progenitor cells in a somatic tumor suppressor mouse model. Cancer Cell. 2009;15:45–56.
-
(2009)
Cancer Cell
, vol.15
, pp. 45-56
-
-
Alcantara Llaguno, S.1
Chen, J.2
Kwon, C.H.3
Jackson, E.L.4
Li, Y.5
Burns, D.K.6
Alvarez-Buylla, A.7
Parada, L.F.8
-
28
-
-
75649109727
-
Combinations of genetic mutations in the adult neural stem cell compartment determine brain tumor phenotypes
-
Jacques TS, Swales A, Brzozowski MJ, Hen-riquez NV, Linehan JM, Mirzadeh Z, O’Malley C, Naumann H, Alvarez-Buylla A, Brandner S. Combinations of genetic mutations in the adult neural stem cell compartment determine brain tumor phenotypes. EMBO J. 2010;29:222–35.
-
(2010)
EMBO J
, vol.29
, pp. 222-235
-
-
Jacques, T.S.1
Swales, A.2
Brzozowski, M.J.3
Hen-Riquez, N.V.4
Linehan, J.M.5
Mirzadeh, Z.6
O’malley, C.7
Naumann, H.8
Alvarez-Buylla, A.9
Brandner, S.10
-
29
-
-
79960809488
-
Mosaic analysis with double markers reveals tumor cell of origin in glioma
-
Liu C, Sage JC, Miller MR, Verhaak RG, Hip-penmeyer S, Vogel H, Foreman O, Bronson RT, Nishiyama A, Luo L, Zong H. Mosaic analysis with double markers reveals tumor cell of origin in glioma. Cell. 2011;146:209–21.
-
(2011)
Cell
, vol.146
, pp. 209-221
-
-
Liu, C.1
Sage, J.C.2
Miller, M.R.3
Verhaak, R.G.4
Hip-Penmeyer, S.5
Vogel, H.6
Foreman, O.7
Bronson, R.T.8
Nishiyama, A.9
Luo, L.10
Zong, H.11
-
30
-
-
33747195353
-
Induction of plu-ripotent stem cells from mouse embryonic and adult fbroblast cultures by defined factors
-
Takahashi K, Yamanaka S. Induction of plu-ripotent stem cells from mouse embryonic and adult fbroblast cultures by defined factors. Cell. 2006;126:663–76.
-
(2006)
Cell
, vol.126
, pp. 663-676
-
-
Takahashi, K.1
Yamanaka, S.2
-
31
-
-
79956351015
-
Normal and neoplastic nonstem cells can spontaneously convert to a stem-like state
-
Chaffer CL, Brueckmann I, Scheel C, Kaestli AJ, Wiggins PA, Rodrigues LO, Brooks M, Reinhardt F, Su Y, Polyak K, Arendt LM, Ku-perwasser C, Bierie B, Weinberg RA. Normal and neoplastic nonstem cells can spontaneously convert to a stem-like state. Proc Natl Acad Sci U S A. 2011;108:7950–5.
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 7950-7955
-
-
Chaffer, C.L.1
Brueckmann, I.2
Scheel, C.3
Kaestli, A.J.4
Wiggins, P.A.5
Rodrigues, L.O.6
Brooks, M.7
Reinhardt, F.8
Su, Y.9
Polyak, K.10
Arendt, L.M.11
Ku-Perwasser, C.12
Bierie, B.13
Weinberg, R.A.14
-
32
-
-
84875268294
-
Rare somatic cells from human breast tissue exhibit extensive lineage plasticity
-
Roy S, Gascard P, Dumont N, Zhao J, Pan D, Petrie S, Margeta M, Tlsty TD. Rare somatic cells from human breast tissue exhibit extensive lineage plasticity. Proc Natl Acad Sci U S A. 2013;110:4598–603.
-
(2013)
Proc Natl Acad Sci U S A
, vol.110
, pp. 4598-4603
-
-
Roy, S.1
Gascard, P.2
Dumont, N.3
Zhao, J.4
Pan, D.5
Petrie, S.6
Margeta, M.7
Tlsty, T.D.8
-
33
-
-
84887619426
-
Dedifferentiation of committed epithelial cells into stem cells in vivo
-
Tata PR, Mou H, Pardo-Saganta A, Zhao R, Prabhu M, Law BM, Vinarsky V, Cho JL, Breton S, Sahay A, Medoff BD, Rajagopal J. Dedifferentiation of committed epithelial cells into stem cells in vivo. Nature. 2013;503:218–23.
-
(2013)
Nature
, vol.503
, pp. 218-223
-
-
Tata, P.R.1
Mou, H.2
Pardo-Saganta, A.3
Zhao, R.4
Prabhu, M.5
Law, B.M.6
Vinarsky, V.7
Cho, J.L.8
Breton, S.9
Sahay, A.10
Medoff, B.D.11
Rajagopal, J.12
-
34
-
-
84867097416
-
Dll1+ secretory progenitor cells revert to stem cells upon crypt damage
-
van Es JH, Sato T, van de Wetering M, Lyubi-mova A, Nee AN, Gregorieff A, Sasaki N, Ze-instra L, van den Born M, Korving J, Martens AC, Barker N, van Oudenaarden A, Clevers H. Dll1+ secretory progenitor cells revert to stem cells upon crypt damage. Nat Cell Biol. 2012;14:1099–104.
-
(2012)
Nat Cell Biol
, vol.14
, pp. 1099-1104
-
-
Van Es, J.H.1
Sato, T.2
Van De Wetering, M.3
Lyubi-Mova, A.4
Nee, A.N.5
Gregorieff, A.6
Sasaki, N.7
Ze-Instra, L.8
Van Den Born, M.9
Korving, J.10
Martens, A.C.11
Barker, N.12
van Oudenaarden, A.13
Clevers, H.14
-
35
-
-
19044397160
-
Epidermal growth factor receptor and Ink4a/Arf: Convergent mechanisms governing terminal differentiation and transformation along the neural stem cell to astrocyte axis
-
Bachoo RM, Maher EA, Ligon KL, Sharpless NE, Chan SS, You MJ, Tang Y, DeFrances J, Stover E, Weissleder R, Rowitch DH, Louis DN, DePinho RA. Epidermal growth factor receptor and Ink4a/Arf: convergent mechanisms governing terminal differentiation and transformation along the neural stem cell to astrocyte axis. Cancer Cell. 2002;1:269–77.
-
(2002)
Cancer Cell
, vol.1
, pp. 269-277
-
-
Bachoo, R.M.1
Maher, E.A.2
Ligon, K.L.3
Sharpless, N.E.4
Chan, S.S.5
You, M.J.6
Tang, Y.7
Defrances, J.8
Stover, E.9
Weissleder, R.10
Rowitch, D.H.11
Louis, D.N.12
Depinho, R.A.13
-
36
-
-
79952509861
-
Cooperativity within and among Pten, p53, and Rb pathways induces high-grade astrocytoma in adult brain
-
Chow LM, Endersby R, Zhu X, Rankin S, Qu C, Zhang J, Broniscer A, Ellison DW, Baker SJ. Cooperativity within and among Pten, p53, and Rb pathways induces high-grade astrocytoma in adult brain. Cancer Cell. 2011;19:305–16.
-
(2011)
Cancer Cell
, vol.19
, pp. 305-316
-
-
Chow, L.M.1
Endersby, R.2
Zhu, X.3
Rankin, S.4
Qu, C.5
Zhang, J.6
Broniscer, A.7
Ellison, D.W.8
Baker, S.J.9
-
37
-
-
0035425048
-
PDGF autocrine stimulation dedifferentiates cultured astrocytes and induces oligodendrogliomas and oligoastrocy-tomas from neural progenitors and astrocytes in vivo
-
Dai C, Celestino JC, Okada Y, Louis DN, Fuller GN, Holland EC. PDGF autocrine stimulation dedifferentiates cultured astrocytes and induces oligodendrogliomas and oligoastrocy-tomas from neural progenitors and astrocytes in vivo. Genes Dev. 2001;15:1913–25.
-
(2001)
Genes Dev
, vol.15
, pp. 1913-1925
-
-
Dai, C.1
Celestino, J.C.2
Okada, Y.3
Louis, D.N.4
Fuller, G.N.5
Holland, E.C.6
-
38
-
-
79952721477
-
Transdifferentiation of glioblastoma cells into vascular endothelial cells
-
Soda Y, Marumoto T, Friedmann-Morvinski D, Soda M, Liu F, Michiue H, Pastorino S, Yang M, Hoffman RM, Kesari S, Verma IM. Transdifferentiation of glioblastoma cells into vascular endothelial cells. Proc Natl Acad Sci U S A. 2011;108:4274–80.
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 4274-4280
-
-
Soda, Y.1
Marumoto, T.2
Friedmann-Morvinski, D.3
Soda, M.4
Liu, F.5
Michiue, H.6
Pastorino, S.7
Yang, M.8
Hoffman, R.M.9
Kesari, S.10
Verma, I.M.11
-
39
-
-
78650153633
-
Tumour vascularization via endothelial differentiation of glioblastoma stem-like cells
-
Ricci-Vitiani L, Pallini R, Biffoni M, Todaro M, Invernici G, Cenci T, Maira G, Parati EA, Stassi G, Larocca LM, De Maria R. Tumour vascularization via endothelial differentiation of glioblastoma stem-like cells. Nature. 2010;468:824–8.
-
(2010)
Nature
, vol.468
, pp. 824-828
-
-
Ricci-Vitiani, L.1
Pallini, R.2
Biffoni, M.3
Todaro, M.4
Invernici, G.5
Cenci, T.6
Maira, G.7
Parati, E.A.8
Stassi, G.9
Larocca, L.M.10
De Maria, R.11
-
40
-
-
78650098659
-
Glioblastoma stem-like cells give rise to tumour endothe-lium
-
Wang R, Chadalavada K, Wilshire J, Kowalik U, Hovinga KE, Geber A, Fligelman B, Le-versha M, Brennan C, Tabar V. Glioblastoma stem-like cells give rise to tumour endothe-lium. Nature. 2010;468:829–33.
-
(2010)
Nature
, vol.468
, pp. 829-833
-
-
Wang, R.1
Chadalavada, K.2
Wilshire, J.3
Kowalik, U.4
Hovinga, K.E.5
Geber, A.6
Fligelman, B.7
Le-Versha, M.8
Brennan, C.9
Tabar, V.10
-
41
-
-
84875755046
-
Glioblastoma stem cells generate vascular pericytes to support vessel function and tumor growth
-
Cheng L, Huang Z, Zhou W, Wu Q, Donnola S, Liu JK, Fang X, Sloan AE, Mao Y, Lathia JD, Min W, McLendon RE, Rich JN, Bao S. Glioblastoma stem cells generate vascular pericytes to support vessel function and tumor growth. Cell. 2013;153:139–52.
-
(2013)
Cell
, vol.153
, pp. 139-152
-
-
Cheng, L.1
Huang, Z.2
Zhou, W.3
Wu, Q.4
Donnola, S.5
Liu, J.K.6
Fang, X.7
Sloan, A.E.8
Mao, Y.9
Lathia, J.D.10
Min, W.11
McLendon, R.E.12
Rich, J.N.13
Bao, S.14
-
42
-
-
3142753475
-
Cell fusion-independent differentiation of neural stem cells to the endothelial lineage
-
Wurmser AE, Nakashima K, Summers RG, Toni N, D’Amour KA, Lie DC, Gage FH. Cell fusion-independent differentiation of neural stem cells to the endothelial lineage. Nature. 2004;430:350–6.
-
(2004)
Nature
, vol.430
, pp. 350-356
-
-
Wurmser, A.E.1
Nakashima, K.2
Summers, R.G.3
Toni, N.4
D’amour, K.A.5
Lie, D.C.6
Gage, F.H.7
-
43
-
-
34447632643
-
Angiogenesis in brain tumours
-
61–22
-
Jain RK, di Tomaso E, Duda DG, Loeffer JS, Sorensen AG, Batchelor TT. Angiogenesis in brain tumours. Nat Rev Neurosci. 2007;8:61–22.
-
(2007)
Nat Rev Neurosci
, vol.8
-
-
Jain, R.K.1
di Tomaso, E.2
Duda, D.G.3
Loeffer, J.S.4
Sorensen, A.G.5
Batchelor, T.T.6
-
44
-
-
33947191055
-
Phase II trial of bevacizumab and irinotecan in recurrent malignant glioma
-
Vredenburgh JJ, Desjardins A, Herndon JEII, Dowell JM, Reardon DA, Quinn JA, Rich JN, Sathornsumetee S, Gururangan S, Wagner M, Bigner DD, Friedman AH, Friedman HS. Phase II trial of bevacizumab and irinotecan in recurrent malignant glioma. Clin Cancer Res. 2007;13:1253–9.
-
(2007)
Clin Cancer Res
, vol.13
, pp. 1253-1259
-
-
Vredenburgh, J.J.1
Desjardins, A.2
Herndon, J.E.3
Dowell, J.M.4
Reardon, D.A.5
Quinn, J.A.6
Rich, J.N.7
Sathornsumetee, S.8
Gururangan, S.9
Wagner, M.10
Bigner, D.D.11
Friedman, A.H.12
Friedman, H.S.13
-
45
-
-
84898645670
-
Dediffer-entiation and reprogramming: Origins of cancer stem cells
-
Friedmann-Morvinski D, Verma IM. Dediffer-entiation and reprogramming: origins of cancer stem cells. EMBO Rep. 2014;15:244–53.
-
(2014)
EMBO Rep
, vol.15
, pp. 244-253
-
-
Friedmann-Morvinski, D.1
Verma, I.M.2
-
46
-
-
75549083303
-
Tumor heterogeneity: Causes and consequences
-
Marusyk A, Polyak K. Tumor heterogeneity: causes and consequences. Biochim Biophys Acta. 2010;1805(1):105–17.
-
(2010)
Biochim Biophys Acta
, vol.1805
, Issue.1
, pp. 105-117
-
-
Marusyk, A.1
Polyak, K.2
|