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Volumn 214, Issue 6, 2017, Pages 1737-1752

Myeloid-derived miR-223 regulates intestinal inflammation via repression of the NLRP3 inflammasome

(19)  Neudecker, Viola a,j   Haneklaus, Moritz b   Jensen, Owen j   Khailova, Ludmila j   Masterson, Joanne C c,j   Tye, Hazel d,e   Biette, Kathryn c,j   Jedlicka, Paul j   Brodsky, Kelley S j   Gerich, Mark E j   Mack, Matthias f   Robertson, Avril A B g   Cooper, Matthew A g   Furuta, Glenn T c,j   Dinarello, Charles A i,j   O'Neill, Luke A b   Eltzschig, Holger K h,j   Masters, Seth L d,e   McNamee, Eóin N j  


Author keywords

[No Author keywords available]

Indexed keywords

CRYOPYRIN; INFLAMMASOME; INTERLEUKIN 1BETA; MICRORNA 223; ANTIBODY; CCR2 PROTEIN, MOUSE; CHEMOKINE RECEPTOR CCR2; DEXTRAN SULFATE; MICRORNA; MIRN223 MICRORNA, HUMAN; MIRN223 MICRORNA, MOUSE; NANOPARTICLE; NLRP3 PROTEIN, HUMAN; NLRP3 PROTEIN, MOUSE;

EID: 85021853932     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20160462     Document Type: Article
Times cited : (307)

References (49)
  • 1
    • 77952303410 scopus 로고    scopus 로고
    • The NLRP3 inflammasome functions as a negative regulator of tumorigenesis during colitis-associated cancer
    • Allen, I.C., E.M. TeKippe, R.M. Woodford, J.M. Uronis, E.K. Holl, A.B. Rogers, H.H. Herfarth, C. Jobin, and J.P. Ting. 2010. The NLRP3 inflammasome functions as a negative regulator of tumorigenesis during colitis-associated cancer. J. Exp. Med. 207:1045-1056. http ://dx .doi .org/10 .1084/jem .20100050
    • (2010) J. Exp. Med , vol.207 , pp. 1045-1056
    • Allen, I.C.1    TeKippe, E.M.2    Woodford, R.M.3    Uronis, J.M.4    Holl, E.K.5    Rogers, A.B.6    Herfarth, H.H.7    Jobin, C.8    Ting, J.P.9
  • 2
    • 0034659767 scopus 로고    scopus 로고
    • Mice with a selective deletion of the CC chemokine receptors 5 or 2 are protected from dextran sodium sulfate-mediated colitis: Lack of CC chemokine receptor 5 expression results in a NK1.1+ lymphocyte-associated Th2-type immune response in the intestine
    • Andres, P.G., P.L. Beck, E. Mizoguchi, A. Mizoguchi, A.K. Bhan, T. Dawson, W.A. Kuziel, N. Maeda, R.P. MacDermott, D.K. Podolsky, and H.C. Reinecker. 2000. Mice with a selective deletion of the CC chemokine receptors 5 or 2 are protected from dextran sodium sulfate-mediated colitis: Lack of CC chemokine receptor 5 expression results in a NK1.1+ lymphocyte-associated Th2-type immune response in the intestine. J. Immunol. 164:6303-6312. http ://dx .doi .org/10 .4049/jimmunol .164 .12 .6303
    • (2000) J. Immunol , vol.164 , pp. 6303-6312
    • Andres, P.G.1    Beck, P.L.2    Mizoguchi, E.3    Mizoguchi, A.4    Bhan, A.K.5    Dawson, T.6    Kuziel, W.A.7    Maeda, N.8    MacDermott, R.P.9    Podolsky, D.K.10    Reinecker, H.C.11
  • 3
  • 4
    • 84864993041 scopus 로고    scopus 로고
    • New insights into the dichotomous role of innate cytokines in gut homeostasis and inflammation
    • Bamias, G., D. Corridoni, T.T. Pizarro, and F. Cominelli. 2012. New insights into the dichotomous role of innate cytokines in gut homeostasis and inflammation. Cytokine. 59:451-459. http ://dx .doi .org/10 .1016/j .cyto .2012 .06 .014
    • (2012) Cytokine , vol.59 , pp. 451-459
    • Bamias, G.1    Corridoni, D.2    Pizarro, T.T.3    Cominelli, F.4
  • 5
    • 77956128040 scopus 로고    scopus 로고
    • Colitis induced in mice with dextran sulfate sodium (DSS) is mediated by the NLRP3 inflammasome
    • Bauer, C., P. Duewell, C. Mayer, H.A. Lehr, K.A. Fitzgerald, M. Dauer, J. Tschopp, S. Endres, E. Latz, and M. Schnurr. 2010. Colitis induced in mice with dextran sulfate sodium (DSS) is mediated by the NLRP3 inflammasome. Gut. 59:1192-1199. http ://dx .doi .org/10 .1136/gut .2009 .197822
    • (2010) Gut , vol.59 , pp. 1192-1199
    • Bauer, C.1    Duewell, P.2    Mayer, C.3    Lehr, H.A.4    Fitzgerald, K.A.5    Dauer, M.6    Tschopp, J.7    Endres, S.8    Latz, E.9    Schnurr, M.10
  • 8
    • 84879068635 scopus 로고    scopus 로고
    • The role of polymorphonuclear leukocyte trafficking in the perpetuation of inflammation during inflammatory bowel disease
    • Brazil, J.C., N.A. Louis, and C.A. Parkos. 2013. The role of polymorphonuclear leukocyte trafficking in the perpetuation of inflammation during inflammatory bowel disease. Inflamm. Bowel Dis. 19:1556-1565. http ://dx .doi .org/10 .1097/MIB .0b013e318281f54e
    • (2013) Inflamm. Bowel Dis , vol.19 , pp. 1556-1565
    • Brazil, J.C.1    Louis, N.A.2    Parkos, C.A.3
  • 10
    • 0028898529 scopus 로고
    • Mucosal imbalance of IL-1 and IL-1 receptor antagonist in inflammatory bowel disease A novel mechanism of chronic intestinal inflammation
    • Casini-Raggi, V., L. Kam, Y.J. Chong, C. Fiocchi, T.T. Pizarro, and F. Cominelli. 1995. Mucosal imbalance of IL-1 and IL-1 receptor antagonist in inflammatory bowel disease. A novel mechanism of chronic intestinal inflammation. J. Immunol. 154:2434-2440
    • (1995) J. Immunol , vol.154 , pp. 2434-2440
    • Casini-Raggi, V.1    Kam, L.2    Chong, Y.J.3    Fiocchi, C.4    Pizarro, T.T.5    Cominelli, F.6
  • 15
    • 84863430273 scopus 로고    scopus 로고
    • The mammalian microRNA response to bacterial infections
    • Eulalio, A., L. Schulte, and J. Vogel. 2012. The mammalian microRNA response to bacterial infections. RNA Biol. 9:742-750. http ://dx .doi .org/10 .4161/rna .20018
    • (2012) RNA Biol , vol.9 , pp. 742-750
    • Eulalio, A.1    Schulte, L.2    Vogel, J.3
  • 16
    • 0031781603 scopus 로고    scopus 로고
    • Inflammatory bowel disease: Etiology and pathogenesis
    • Fiocchi, C. 1998. Inflammatory bowel disease: Etiology and pathogenesis. Gastroenterology. 115:182-205. http ://dx .doi .org/10 .1016/S0016-5085 (98)70381-6
    • (1998) Gastroenterology , vol.115 , pp. 182-205
    • Fiocchi, C.1
  • 19
    • 84881555502 scopus 로고    scopus 로고
    • miR-223: Infection, inflammation and cancer
    • Haneklaus, M., M. Gerlic, L.A. O'Neill, and S.L. Masters. 2013. miR-223: Infection, inflammation and cancer. J. Intern. Med. 274:215-226. http ://dx .doi .org/10 .1111/joim .12099
    • (2013) J. Intern. Med , vol.274 , pp. 215-226
    • Haneklaus, M.1    Gerlic, M.2    O'Neill, L.A.3    Masters, S.L.4
  • 22
    • 33747821745 scopus 로고    scopus 로고
    • RegRNA: An integrated web server for identifying regulatory RNA motifs and elements
    • Huang, H.Y., C.H. Chien, K.H. Jen, and H.D. Huang. 2006. RegRNA: An integrated web server for identifying regulatory RNA motifs and elements. Nucleic Acids Res. 34:W429-W434. http ://dx .doi .org/10 .1093/nar/gkl333
    • (2006) Nucleic Acids Res , vol.34 , pp. W429-W434
    • Huang, H.Y.1    Chien, C.H.2    Jen, K.H.3    Huang, H.D.4
  • 26
    • 77955924350 scopus 로고    scopus 로고
    • MicroRNAs modulate the noncanonical transcription factor NF-κB pathway by regulating expression of the kinase IKKα during macrophage differentiation
    • Li, T., M.J. Morgan, S. Choksi, Y. Zhang, Y.S. Kim, and Z.G. Liu. 2010. MicroRNAs modulate the noncanonical transcription factor NF-κB pathway by regulating expression of the kinase IKKα during macrophage differentiation. Nat. Immunol. 11:799-805. http ://dx .doi .org/10 .1038/ni .1918
    • (2010) Nat. Immunol , vol.11 , pp. 799-805
    • Li, T.1    Morgan, M.J.2    Choksi, S.3    Zhang, Y.4    Kim, Y.S.5    Liu, Z.G.6
  • 27
    • 0025442212 scopus 로고
    • Role of interleukin 1 in inflammatory bowel disease: Enhanced production during active disease
    • Ligumsky, M., P.L. Simon, F. Karmeli, and D. Rachmilewitz. 1990. Role of interleukin 1 in inflammatory bowel disease: Enhanced production during active disease. Gut. 31:686-689. http ://dx .doi .org/10 .1136/gut .31 .6 .686
    • (1990) Gut , vol.31 , pp. 686-689
    • Ligumsky, M.1    Simon, P.L.2    Karmeli, F.3    Rachmilewitz, D.4
  • 28
    • 84883685051 scopus 로고    scopus 로고
    • Opposing functions of classic and novel IL-1 family members in gut health and disease
    • Lopetuso, L.R., S. Chowdhry, and T.T. Pizarro. 2013. Opposing functions of classic and novel IL-1 family members in gut health and disease. Front. Immunol. 4:181. http ://dx .doi .org/10 .3389/fimmu .2013 .00181
    • (2013) Front. Immunol , vol.4 , pp. 181
    • Lopetuso, L.R.1    Chowdhry, S.2    Pizarro, T.T.3
  • 29
    • 84859492693 scopus 로고    scopus 로고
    • The NLRP3/ASC/caspase-1 axis regulates IL-1β processing in neutrophils
    • Mankan, A.K., T. Dau, D. Jenne, and V. Hornung. 2012. The NLRP3/ASC/caspase-1 axis regulates IL-1β processing in neutrophils. Eur. J. Immunol. 42:710-715. http ://dx .doi .org/10 .1002/eji .201141921
    • (2012) Eur. J. Immunol , vol.42 , pp. 710-715
    • Mankan, A.K.1    Dau, T.2    Jenne, D.3    Hornung, V.4
  • 32
    • 58849101761 scopus 로고    scopus 로고
    • Activation of murine macrophages
    • Chapter 14 Unit 14.2
    • Mosser, D.M., and X. Zhang. 2008. Activation of murine macrophages. Curr. Protoc. Immunol. Chapter 14:Unit 14.2. http ://dx .doi .org/10 .1002/0471142735 .im1402s83
    • (2008) Curr. Protoc. Immunol
    • Mosser, D.M.1    Zhang, X.2
  • 33
    • 0035495399 scopus 로고    scopus 로고
    • Man the barrier! Strategic defences in the intestinal mucosa
    • Nagler-Anderson, C. 2001. Man the barrier! Strategic defences in the intestinal mucosa. Nat. Rev. Immunol. 1:59-67. http ://dx .doi .org/10 .1038/35095573
    • (2001) Nat. Rev. Immunol , vol.1 , pp. 59-67
    • Nagler-Anderson, C.1
  • 35
    • 75649139134 scopus 로고    scopus 로고
    • Physiological and pathological roles for microRNAs in the immune system
    • O'Connell, R.M., D.S. Rao, A.A. Chaudhuri, and D. Baltimore. 2010. Physiological and pathological roles for microRNAs in the immune system. Nat. Rev. Immunol. 10:111-122. http ://dx .doi .org/10 .1038/nri2708
    • (2010) Nat. Rev. Immunol , vol.10 , pp. 111-122
    • O'Connell, R.M.1    Rao, D.S.2    Chaudhuri, A.A.3    Baltimore, D.4
  • 36
    • 84945259780 scopus 로고    scopus 로고
    • Assessment of circulating microRNAs for the diagnosis and disease activity evaluation in patients with ulcerative colitis by using the nanostring technology
    • Polytarchou, C., A. Oikonomopoulos, S. Mahurkar, A. Touroutoglou, G. Koukos, D.W. Hommes, and D. Iliopoulos. 2015. Assessment of circulating microRNAs for the diagnosis and disease activity evaluation in patients with ulcerative colitis by using the nanostring technology. Inflamm. Bowel Dis. 21:2533-2539. http ://dx .doi .org/10 .1097/MIB .0000000000000547
    • (2015) Inflamm. Bowel Dis , vol.21 , pp. 2533-2539
    • Polytarchou, C.1    Oikonomopoulos, A.2    Mahurkar, S.3    Touroutoglou, A.4    Koukos, G.5    Hommes, D.W.6    Iliopoulos, D.7
  • 37
    • 77950354353 scopus 로고    scopus 로고
    • Cell-cycle regulator E2F1 and microRNA-223 comprise an autoregulatory negative feedback loop in acute myeloid leukemia
    • Pulikkan, J.A., V. Dengler, P.S. Peramangalam, A.A. Peer Zada, C. Müller-Tidow, S.K. Bohlander, D.G. Tenen, and G. Behre. 2010. Cell-cycle regulator E2F1 and microRNA-223 comprise an autoregulatory negative feedback loop in acute myeloid leukemia. Blood. 115:1768-1778. http ://dx .doi .org/10 .1182/blood-2009-08-240101
    • (2010) Blood , vol.115 , pp. 1768-1778
    • Pulikkan, J.A.1    Dengler, V.2    Peramangalam, P.S.3    Peer Zada, A.A.4    Müller-Tidow, C.5    Bohlander, S.K.6    Tenen, D.G.7    Behre, G.8
  • 39
    • 0027451455 scopus 로고
    • Enhanced secretion of tumour necrosis factor-alpha, IL-6, and IL-1β by isolated lamina propria mononuclear cells from patients with ulcerative colitis and Crohn's disease
    • Reinecker, H.C., M. Steffen, T. Witthoeft, I. Pflueger, S. Schreiber, R.P. MacDermott, and A. Raedler. 1993. Enhanced secretion of tumour necrosis factor-alpha, IL-6, and IL-1β by isolated lamina propria mononuclear cells from patients with ulcerative colitis and Crohn's disease. Clin. Exp. Immunol. 94:174-181. http ://dx .doi .org/10 .1111/j .1365-2249 .1993 .tb05997 .x
    • (1993) Clin. Exp. Immunol , vol.94 , pp. 174-181
    • Reinecker, H.C.1    Steffen, M.2    Witthoeft, T.3    Pflueger, I.4    Schreiber, S.5    MacDermott, R.P.6    Raedler, A.7
  • 40
    • 33646778482 scopus 로고    scopus 로고
    • The Montreal classification of inflammatory bowel disease: Controversies, consensus, and implications
    • Satsangi, J., M.S. Silverberg, S. Vermeire, and J.F. Colombel. 2006. The Montreal classification of inflammatory bowel disease: Controversies, consensus, and implications. Gut. 55:749-753. http ://dx .doi .org/10 .1136/gut .2005 .082909
    • (2006) Gut , vol.55 , pp. 749-753
    • Satsangi, J.1    Silverberg, M.S.2    Vermeire, S.3    Colombel, J.F.4
  • 41
    • 82755189251 scopus 로고    scopus 로고
    • Selective upregulation of microRNA expression in peripheral blood leukocytes in IL-10-/-mice precedes expression in the colon
    • Schaefer, J.S., D. Montufar-Solis, N. Vigneswaran, and J.R. Klein. 2011. Selective upregulation of microRNA expression in peripheral blood leukocytes in IL-10-/-mice precedes expression in the colon. J. Immunol. 187:5834-5841. http ://dx .doi .org/10 .4049/jimmunol .1100922
    • (2011) J. Immunol , vol.187 , pp. 5834-5841
    • Schaefer, J.S.1    Montufar-Solis, D.2    Vigneswaran, N.3    Klein, J.R.4
  • 42
    • 84928175356 scopus 로고    scopus 로고
    • Distinct commensals induce interleukin-1β via NLRP3 inflammasome in inflammatory monocytes to promote intestinal inflammation in response to injury
    • Seo, S.U., N. Kamada, R. Muñoz-Planillo, Y.G. Kim, D. Kim, Y. Koizumi, M. Hasegawa, S.D. Himpsl, H.P. Browne, T.D. Lawley, et al. 2015. Distinct commensals induce interleukin-1β via NLRP3 inflammasome in inflammatory monocytes to promote intestinal inflammation in response to injury. Immunity. 42:744-755. http ://dx .doi .org/10 .1016/j .immuni .2015 .03 .004
    • (2015) Immunity , vol.42 , pp. 744-755
    • Seo, S.U.1    Kamada, N.2    Muñoz-Planillo, R.3    Kim, Y.G.4    Kim, D.5    Koizumi, Y.6    Hasegawa, M.7    Himpsl, S.D.8    Browne, H.P.9    Lawley, T.D.10
  • 44
    • 84902588650 scopus 로고    scopus 로고
    • Nlrp3 activation in the intestinal epithelium protects against a mucosal pathogen
    • Song-Zhao, G.X., N. Srinivasan, J. Pott, D. Baban, G. Frankel, and K.J. Maloy. 2014. Nlrp3 activation in the intestinal epithelium protects against a mucosal pathogen. Mucosal Immunol. 7:763-774. http ://dx .doi .org/10 .1038/mi .2013 .94
    • (2014) Mucosal Immunol , vol.7 , pp. 763-774
    • Song-Zhao, G.X.1    Srinivasan, N.2    Pott, J.3    Baban, D.4    Frankel, G.5    Maloy, K.J.6
  • 45
    • 77950002937 scopus 로고    scopus 로고
    • The NLRP3 inflammasome protects against loss of epithelial integrity and mortality during experimental colitis
    • Zaki, M.H., K.L. Boyd, P. Vogel, M.B. Kastan, M. Lamkanfi, and T.D. Kanneganti. 2010. The NLRP3 inflammasome protects against loss of epithelial integrity and mortality during experimental colitis. Immunity. 32:379-391. http ://dx .doi .org/10 .1016/j .immuni .2010 .03 .003
    • (2010) Immunity , vol.32 , pp. 379-391
    • Zaki, M.H.1    Boyd, K.L.2    Vogel, P.3    Kastan, M.B.4    Lamkanfi, M.5    Kanneganti, T.D.6
  • 46
    • 79953084107 scopus 로고    scopus 로고
    • The Nlrp3 inflammasome: Contributions to intestinal homeostasis
    • Zaki, M.H., M. Lamkanfi, and T.D. Kanneganti. 2011. The Nlrp3 inflammasome: Contributions to intestinal homeostasis. Trends Immunol. 32:171-179. http ://dx .doi .org/10 .1016/j .it .2011 .02 .002
    • (2011) Trends Immunol , vol.32 , pp. 171-179
    • Zaki, M.H.1    Lamkanfi, M.2    Kanneganti, T.D.3
  • 47
    • 84906247578 scopus 로고    scopus 로고
    • Inflammasome activation has an important role in the development of spontaneous colitis
    • Zhang, J., S. Fu, S. Sun, Z. Li, and B. Guo. 2014. Inflammasome activation has an important role in the development of spontaneous colitis. Mucosal Immunol. 7:1139-1150. http ://dx .doi .org/10 .1038/mi .2014 .1
    • (2014) Mucosal Immunol , vol.7 , pp. 1139-1150
    • Zhang, J.1    Fu, S.2    Sun, S.3    Li, Z.4    Guo, B.5
  • 48
    • 84946822396 scopus 로고    scopus 로고
    • MicroRNA-223 regulates the differentiation and function of intestinal dendritic cells and macrophages by targeting C/EBPβ
    • Zhou, H., J. Xiao, N. Wu, C. Liu, J. Xu, F. Liu, and L. Wu. 2015. MicroRNA-223 regulates the differentiation and function of intestinal dendritic cells and macrophages by targeting C/EBPβ. Cell Reports. 13:1149-1160. http ://dx .doi .org/10 .1016/j .celrep .2015 .09 .073
    • (2015) Cell Reports , vol.13 , pp. 1149-1160
    • Zhou, H.1    Xiao, J.2    Wu, N.3    Liu, C.4    Xu, J.5    Liu, F.6    Wu, L.7
  • 49
    • 84870900504 scopus 로고    scopus 로고
    • Ly6C hi monocytes in the inflamed colon give rise to proinflammatory effector cells and migratory antigen-presenting cells
    • Zigmond, E., C. Varol, J. Farache, E. Elmaliah, A.T. Satpathy, G. Friedlander, M. Mack, N. Shpigel, I.G. Boneca, K.M. Murphy, et al. 2012. Ly6C hi monocytes in the inflamed colon give rise to proinflammatory effector cells and migratory antigen-presenting cells. Immunity. 37:1076-1090. http ://dx .doi .org/10 .1016/j .immuni .2012 .08 .026
    • (2012) Immunity , vol.37 , pp. 1076-1090
    • Zigmond, E.1    Varol, C.2    Farache, J.3    Elmaliah, E.4    Satpathy, A.T.5    Friedlander, G.6    Mack, M.7    Shpigel, N.8    Boneca, I.G.9    Murphy, K.M.10


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