Interleukin 1β Mediates Intestinal Inflammation in Mice and Patients With Interleukin 10 Receptor Deficiency

Gastroenterology

Volumn 151, Issue 6, 2016, Pages 1100-1104

  Shouval, Dror S ^a,b,c,d   Biswas, Amlan ^a,b   Kang, Yu Hui ^a,b   Griffith, Alexandra E ^a   Konnikova, Liza ^b,e   Mascanfroni, Ivan D ^b,e   Redhu, Naresh S ^a,b   Frei, Sandra M ^a,b   Field, Michael ^a   Doty, Andria L ^f   Goldsmith, Jeffrey D ^a,b   Bhan, Atul K ^b,g   Loizides, Anthony ^h   Weiss, Batia ^c,d   Yerushalmi, Baruch ⁱ   Yanagi, Tadahiro ^j   Lui, Xiuli ^f   Quintana, Francisco J ^b,e   Muise, Aleixo M ^k,l,m   Klein, Christoph ⁿ   Horwitz, Bruce H ^b,e   Glover, Sarah C ^f   Bousvaros, Athos ^a,b   Snapper, Scott B ^a,b,e   more..

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c SHEBA MEDICAL CENTER   (Israel)

^d TEL AVIV UNIVERSITY   (Israel)

^e BRIGHAM AND WOMEN S HOSPITAL   (United States)

^f UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^g MASSACHUSETTS GENERAL HOSPITAL   (United States)

^h CHILDREN S HOSPITAL AT MONTEFIORE   (United States)

ⁱ BEN GURION UNIVERSITY OF THE NEGEV   (Israel)

^j KURUME UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^k HOSPITAL FOR SICK CHILDREN RESEARCH INSTITUTE   (Canada)

^l HOSPITAL FOR SICK CHILDREN   (Canada)

^m UNIVERSITY OF TORONTO   (Canada)

ⁿ LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

more..

Author keywords

Caspase 1; Treg Cell; Ubiquitination; VEOIBD

Indexed keywords

ANAKINRA; CRYOPYRIN; GAMMA INTERFERON; INFLAMMASOME; INTERLEUKIN 10; INTERLEUKIN 10 RECEPTOR; INTERLEUKIN 17; INTERLEUKIN 1BETA; LIPOPOLYSACCHARIDE; TUMOR NECROSIS FACTOR; ADENOSINE TRIPHOSPHATE; ANTIRHEUMATIC AGENT; CASPASE 8; HOMEODOMAIN PROTEIN; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 10 RECEPTOR ALPHA; RAG-1 PROTEIN;

ADULT; ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CASE REPORT; CD4+ T LYMPHOCYTE; CHILD; COLITIS; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; DISEASE SEVERITY; HISTOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; INNATE IMMUNITY; LOSS OF FUNCTION MUTATION; MACROPHAGE; MOUSE; NONHUMAN; ONSET AGE; PRESCHOOL CHILD; PRIORITY JOURNAL; PROTEIN PROCESSING; REGULATORY T LYMPHOCYTE; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; TREATMENT RESPONSE; ANIMAL; CELL CULTURE; DEFICIENCY; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; IMMUNOLOGY; INFLAMMATORY BOWEL DISEASES; KNOCKOUT MOUSE; METABOLISM; MUTATION; PATHOLOGY; PROTEIN SYNTHESIS;

ADENOSINE TRIPHOSPHATE; ADULT; ANIMALS; ANTIRHEUMATIC AGENTS; CASPASE 8; CD4-POSITIVE T-LYMPHOCYTES; CELLS, CULTURED; CHILD, PRESCHOOL; COLITIS; GENE EXPRESSION REGULATION; HOMEODOMAIN PROTEINS; HUMANS; IMMUNITY, INNATE; INFLAMMASOMES; INFLAMMATORY BOWEL DISEASES; INTERFERON-GAMMA; INTERLEUKIN 1 RECEPTOR ANTAGONIST PROTEIN; INTERLEUKIN-10; INTERLEUKIN-10 RECEPTOR ALPHA SUBUNIT; INTERLEUKIN-17; INTERLEUKIN-1BETA; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; MICE, KNOCKOUT; MUTATION; NLR FAMILY, PYRIN DOMAIN-CONTAINING 3 PROTEIN; PROTEIN BIOSYNTHESIS; RECEPTORS, INTERLEUKIN-10; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84997199517     PISSN: 00165085     EISSN: 15280012     Source Type: Journal    
DOI: 10.1053/j.gastro.2016.08.055     Document Type: Article

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