Therapeutic inhibition of miR-375 attenuates post-myocardial infarction inflammatory response and left ventricular dysfunction via PDK-1-AKT signalling axis

Cardiovascular Research

Volumn 113, Issue 8, 2017, Pages 938-949

  Garikipati, Venkata N S ^a   Verma, Suresh K ^a   Jolardarashi, Darukeshwara ^b   Cheng, Zhongjian ^a   Ibetti, Jessica ^a   Cimini, Maria ^a   Tang, Yan ^a   Khan, Mohsin ^a   Yue, Yujia ^a   Benedict, Cindy ^a   Nickoloff, Emily ^a   Truongcao, May M ^a   Gao, Erhe ^a   Krishnamurthy, Prasanna ^b   Goukassian, David A ^a   Koch, Walter J ^a   Kishore, Raj ^a  

^a TEMPLE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b and Radiation Oncology   (United States)

Author keywords

Cardiac repair; Inflammation; MiRNA; Myocardial infarction

Indexed keywords

DNA NUCLEOTIDYLEXOTRANSFERASE; MICRORNA 375; PHOSPHOINOSITIDE DEPENDENT PROTEIN KINASE 1; PROTEIN KINASE B; MICRORNA; MIRN375 MICRORNA, MOUSE; PROTEIN SERINE THREONINE KINASE; PYRUVATE DEHYDROGENASE (ACETYL-TRANSFERRING) KINASE;

ADULT; AGED; ANIMAL EXPERIMENT; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CAPILLARY DENSITY; CELL ISOLATION; CONTROLLED STUDY; DRESSLER SYNDROME; ECHOCARDIOGRAPHY; ENDOTHELIUM CELL; ENZYME PHOSPHORYLATION; FEMALE; FLOW CYTOMETRY; HEART LEFT VENTRICLE FAILURE; HEART MUSCLE ISCHEMIA; HEART TISSUE; HUMAN; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; MACROPHAGE; MALE; MIDDLE AGED; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TUNEL ASSAY; ANIMAL; C57BL MOUSE; CARDIAC MUSCLE; CARDIAC MUSCLE CELL; CELL MOTION; GENETICS; HEART INFARCTION; HEART LEFT VENTRICLE FUNCTION; HEART VENTRICLE REMODELING; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY; SIGNAL TRANSDUCTION;

ANIMALS; CELL MOVEMENT; MACROPHAGES; MALE; MICE, INBRED C57BL; MICRORNAS; MYOCARDIAL INFARCTION; MYOCARDIUM; MYOCYTES, CARDIAC; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; VENTRICULAR DYSFUNCTION, LEFT; VENTRICULAR FUNCTION, LEFT; VENTRICULAR REMODELING;

EID: 85021794445     PISSN: 00086363     EISSN: 17553245     Source Type: Journal    
DOI: 10.1093/cvr/cvx052     Document Type: Article

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