Interleukin-10 treatment attenuates pressure overload-induced hypertrophic remodeling and improves heart function via signal transducers and activators of transcription 3-dependent inhibition of nuclear factor-κB

Circulation

Volumn 126, Issue 4, 2012, Pages 418-429

  Verma, Suresh Kumar ^a   Krishnamurthy, Prasanna ^a   Barefield, David ^b   Singh, Neha ^a   Gupta, Rajesh ^a   Lambers, Erin ^a   Thal, Melissa ^a   MacKie, Alexander ^a   Hoxha, Eneda ^a   Ramirez, Veronica ^a   Qin, Gangjian ^a   Sadayappan, Sakthivel ^b   Ghosh, Asish K ^a   Kishore, Raj ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

^b LOYOLA UNIVERSITY CHICAGO   (United States)

Author keywords

apoptosis; heart failure; hypertrophy; interleukins; myocardium; remodeling; signal transduction

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; ISOPRENALINE; RECOMBINANT INTERLEUKIN 10; STAT3 PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; GENE DELETION; HEART FUNCTION; HEART LEFT VENTRICLE FAILURE; HEART LEFT VENTRICLE OVERLOAD; HEART MUSCLE CELL; HEART VENTRICLE HYPERTROPHY; HEART VENTRICLE REMODELING; MOUSE; MYOBLAST; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION;

ANIMALS; CARDIOMEGALY; DISEASE MODELS, ANIMAL; DISEASE SUSCEPTIBILITY; FIBROSIS; INTERLEUKIN-10; ISOPROTERENOL; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MYOBLASTS, CARDIAC; MYOCARDIUM; NF-KAPPA B; RATS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR; VENTRICULAR DYSFUNCTION, LEFT; VENTRICULAR REMODELING;

EID: 84864277489     PISSN: 00097322     EISSN: 15244539     Source Type: Journal    
DOI: 10.1161/CIRCULATIONAHA.112.112185     Document Type: Article

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