-
1
-
-
0037118259
-
Neuronal alpha-synucleinopathy with severe movement disorder in mice expressing A53T human alpha-synuclein
-
Giasson BI, Duda JE, Quinn SM, Zhang B, Trojanowski JQ, Lee VM. Neuronal alpha-synucleinopathy with severe movement disorder in mice expressing A53T human alpha-synuclein. Neuron 2002; 34: 521–533.
-
(2002)
Neuron
, vol.34
, pp. 521-533
-
-
Giasson, B.I.1
Duda, J.E.2
Quinn, S.M.3
Zhang, B.4
Trojanowski, J.Q.5
Lee, V.M.6
-
2
-
-
0038051266
-
The role of glial reaction and inflammation in Parkinson's disease
-
Hirsch EC, Breidert T, Rousselet E, Hunot S, Hartmann A, Michel PP. The role of glial reaction and inflammation in Parkinson's disease. AnnNYAcad Sci 2003; 991: 214–228.
-
(2003)
Annnyacad Sci
, vol.991
, pp. 214-228
-
-
Hirsch, E.C.1
Breidert, T.2
Rousselet, E.3
Hunot, S.4
Hartmann, A.5
Michel, P.P.6
-
3
-
-
2542455543
-
Evidence of active microglia in substantia nigra pars compacta of parkinsonian monkeys 1 year after MPTP exposure
-
Barcia C, Sanchez Bahillo A, Fernandez-Villalba E, Bautista V, Poza YPM, Fernandez-Barreiro A et al. Evidence of active microglia in substantia nigra pars compacta of parkinsonian monkeys 1 year after MPTP exposure. Glia 2004; 46: 402–409.
-
(2004)
Glia
, vol.46
, pp. 402-409
-
-
Barcia, C.1
Sanchez Bahillo, A.2
Fernandez-Villalba, E.3
Bautista, V.4
Poza, Y.P.M.5
Fernandez-Barreiro, A.6
-
4
-
-
0242384667
-
Presence of reactive microglia in monkey substantia nigra years after 1-methyl-4-phenyl-1,2,3, 6-tetrahydropyridine administration
-
McGeer PL, Schwab C, Parent A, Doudet D. Presence of reactive microglia in monkey substantia nigra years after 1-methyl-4-phenyl-1,2,3, 6-tetrahydropyridine administration. Ann Neurol 2003; 54: 599–604.
-
(2003)
Ann Neurol
, vol.54
, pp. 599-604
-
-
McGeer, P.L.1
Schwab, C.2
Parent, A.3
Doudet, D.4
-
5
-
-
0036935553
-
An inflammatory review of Parkinson's disease
-
Orr CF, Rowe DB, Halliday GM. An inflammatory review of Parkinson's disease. Prog Neurobiol 2002; 68: 325–340.
-
(2002)
Prog Neurobiol
, vol.68
, pp. 325-340
-
-
Orr, C.F.1
Rowe, D.B.2
Halliday, G.M.3
-
6
-
-
33750373343
-
Role of cytokines in inflammatory process in Parkinson's disease
-
Sawada M, Imamura K, Nagatsu T. Role of cytokines in inflammatory process in Parkinson's disease. J Neural Transm Suppl 2006; 70: 373–381.
-
(2006)
J Neural Transm Suppl
, vol.70
, pp. 373-381
-
-
Sawada, M.1
Imamura, K.2
Nagatsu, T.3
-
7
-
-
84865973639
-
The classification of microglial activation phenotypes on neurodegeneration and regeneration in Alzheimer's disease brain
-
Varnum MM, Ikezu T. The classification of microglial activation phenotypes on neurodegeneration and regeneration in Alzheimer's disease brain. Arch Immunol Ther Exp (Warsz) 2012; 60: 251–266.
-
(2012)
Arch Immunol Ther Exp (Warsz)
, vol.60
, pp. 251-266
-
-
Varnum, M.M.1
Ikezu, T.2
-
9
-
-
84877965817
-
Neuroimmunological processes in Parkinson's disease and their relation to alpha-synuclein: Microglia as the referee between neuronal processes and peripheral immunity
-
Sanchez-Guajardo V, Barnum CJ, Tansey MG, Romero-Ramos M. Neuroimmunological processes in Parkinson's disease and their relation to alpha-synuclein: microglia as the referee between neuronal processes and peripheral immunity. ASN Neuro 2013; 5: 113–139.
-
(2013)
ASN Neuro
, vol.5
, pp. 113-139
-
-
Sanchez-Guajardo, V.1
Barnum, C.J.2
Tansey, M.G.3
Romero-Ramos, M.4
-
10
-
-
30744472146
-
In vivo imaging of microglial activation with [11C](R)-PK11195 PET in idiopathic Parkinson's disease
-
Gerhard A, Pavese N, Hotton G, Turkheimer F, Es M, Hammers A et al. In vivo imaging of microglial activation with [11C](R)-PK11195 PET in idiopathic Parkinson's disease. Neurobiol Dis 2006; 21: 404–412.
-
(2006)
Neurobiol Dis
, vol.21
, pp. 404-412
-
-
Gerhard, A.1
Pavese, N.2
Hotton, G.3
Turkheimer, F.4
Es, M.5
Hammers, A.6
-
11
-
-
77749339881
-
Nrf2 regulates microglial dynamics and neuroinflammation in experimental Parkinson's disease
-
Rojo AI, Innamorato NG, Martin-Moreno AM, De Ceballos ML, Yamamoto M, Cuadrado A. Nrf2 regulates microglial dynamics and neuroinflammation in experimental Parkinson's disease. Glia 2010; 58: 588–598.
-
(2010)
Glia
, vol.58
, pp. 588-598
-
-
Rojo, A.I.1
Innamorato, N.G.2
Martin-Moreno, A.M.3
de Ceballos, M.L.4
Yamamoto, M.5
Cuadrado, A.6
-
12
-
-
0037205060
-
The water-soluble fraction of bee venom produces antinociceptive and antiinflammatory effects on rheumatoid arthritis in rats
-
Kwon YB, Lee HJ, Han HJ, Mar WC, Kang SK, Yoon OB et al. The water-soluble fraction of bee venom produces antinociceptive and antiinflammatory effects on rheumatoid arthritis in rats. Life Sci 2002; 71: 191–204.
-
(2002)
Life Sci
, vol.71
, pp. 191-204
-
-
Kwon, Y.B.1
Lee, H.J.2
Han, H.J.3
Mar, W.C.4
Kang, S.K.5
Yoon, O.B.6
-
13
-
-
34447312502
-
Therapeutic application of anti-arthritis, pain-releasing, and anti-cancer effects of bee venom and its constituent compounds
-
Son DJ, Lee JW, Lee YH, Song HS, Lee CK, Hong JT. Therapeutic application of anti-arthritis, pain-releasing, and anti-cancer effects of bee venom and its constituent compounds. Pharmacol Ther 2007; 115: 246–270.
-
(2007)
Pharmacol Ther
, vol.115
, pp. 246-270
-
-
Son, D.J.1
Lee, J.W.2
Lee, Y.H.3
Song, H.S.4
Lee, C.K.5
Hong, J.T.6
-
14
-
-
84865582800
-
Effectiveness of acupuncture and bee venom acupuncture in idiopathic Parkinson's disease
-
Cho SY, Shim SR, Rhee HY, Park HJ, Jung WS, Moon SK et al. Effectiveness of acupuncture and bee venom acupuncture in idiopathic Parkinson's disease. Parkinsonism Relat Disord 2012; 18: 948–952.
-
(2012)
Parkinsonism Relat Disord
, vol.18
, pp. 948-952
-
-
Cho, S.Y.1
Shim, S.R.2
Rhee, H.Y.3
Park, H.J.4
Jung, W.S.5
Moon, S.K.6
-
15
-
-
34547681342
-
Venom therapy in multiple sclerosis
-
Mirshafiey A. Venom therapy in multiple sclerosis. Neuropharmacology 2007; 53: 353–361.
-
(2007)
Neuropharmacology
, vol.53
, pp. 353-361
-
-
Mirshafiey, A.1
-
16
-
-
84867204086
-
Neuro-protective effects of bee venom by suppression of neuroinflammatory responses in a mouse model of Parkinson's disease: Role of regulatory T cells
-
Chung ES, Kim H, Lee G, Park S, Bae H. Neuro-protective effects of bee venom by suppression of neuroinflammatory responses in a mouse model of Parkinson's disease: role of regulatory T cells. Brain Behav Immun 2012; 26: 1322–1330.
-
(2012)
Brain Behav Immun
, vol.26
, pp. 1322-1330
-
-
Chung, E.S.1
Kim, H.2
Lee, G.3
Park, S.4
Bae, H.5
-
17
-
-
0015527253
-
Bee and wasp venoms
-
Habermann E. Bee and wasp venoms. Science 1972; 177: 314–322.
-
(1972)
Science
, vol.177
, pp. 314-322
-
-
Habermann, E.1
-
18
-
-
33846894107
-
Synthesis of sn-1 functionalized phospholipids as substrates for secretory phospholipase A2
-
Linderoth L, Peters GH, Jorgensen K, Madsen R, Andresen TL. Synthesis of sn-1 functionalized phospholipids as substrates for secretory phospholipase A2. Chem Phys Lipids 2007; 146: 54–66.
-
(2007)
Chem Phys Lipids
, vol.146
, pp. 54-66
-
-
Linderoth, L.1
Peters, G.H.2
Jorgensen, K.3
Madsen, R.4
Andresen, T.L.5
-
19
-
-
0025869402
-
Role of phospholipase in generating lipid second messengers in signal transduction
-
Dennis EA, Rhee SG, Billah MM, Hannun YA. Role of phospholipase in generating lipid second messengers in signal transduction. FASEB J 1991; 5: 2068–2077.
-
(1991)
FASEB J
, vol.5
, pp. 2068-2077
-
-
Dennis, E.A.1
Rhee, S.G.2
Billah, M.M.3
Hannun, Y.A.4
-
20
-
-
0028338536
-
Diversity of group types, regulation, and function of phospholipase A2
-
Dennis EA. Diversity of group types, regulation, and function of phospholipase A2. JBiolChem1994; 269: 13057–13060.
-
(1994)
Jbiolchem
, vol.269
, pp. 13057-13060
-
-
Dennis, E.A.1
-
22
-
-
33746238519
-
Signaling events involved in cytokine and chemokine production induced by secretory phospholipase A2 in human lung macrophages
-
Granata F, Frattini A, Loffredo S, Del Prete A, Sozzani S, Marone G et al. Signaling events involved in cytokine and chemokine production induced by secretory phospholipase A2 in human lung macrophages. Eur J Immunol 2006; 36: 1938–1950.
-
(2006)
Eur J Immunol
, vol.36
, pp. 1938-1950
-
-
Granata, F.1
Frattini, A.2
Loffredo, S.3
Del Prete, A.4
Sozzani, S.5
Marone, G.6
-
23
-
-
0030614354
-
The growing phospholipase A2 superfamily of signal transduction enzymes
-
Dennis EA. The growing phospholipase A2 superfamily of signal transduction enzymes. Trends Biochem Sci 1997; 22: 1–2.
-
(1997)
Trends Biochem Sci
, vol.22
, pp. 1-2
-
-
Dennis, E.A.1
-
24
-
-
0034915340
-
A peptide derived from bee venom-secreted phospholipase A2 inhibits replication of T-cell tropic HIV-1 strains via interaction with the CXCR4 chemokine receptor
-
Fenard D, Lambeau G, Maurin T, Lefebvre JC, Doglio A. A peptide derived from bee venom-secreted phospholipase A2 inhibits replication of T-cell tropic HIV-1 strains via interaction with the CXCR4 chemokine receptor. Mol Pharmacol 2001; 60: 341–347.
-
(2001)
Mol Pharmacol
, vol.60
, pp. 341-347
-
-
Fenard, D.1
Lambeau, G.2
Maurin, T.3
Lefebvre, J.C.4
Doglio, A.5
-
25
-
-
3042653199
-
The catalytic activity, but not receptor binding, of sPLA2s plays a critical role for neurite outgrowth induction in PC12 cells
-
Nakashima S, Kitamoto K, Arioka M. The catalytic activity, but not receptor binding, of sPLA2s plays a critical role for neurite outgrowth induction in PC12 cells. Brain Res 2004; 1015: 207–211.
-
(2004)
Brain Res
, vol.1015
, pp. 207-211
-
-
Nakashima, S.1
Kitamoto, K.2
Arioka, M.3
-
26
-
-
0030804957
-
Dopamine neurotransmission and treatments for Parkinson's disease in the molecular biology era
-
Suppl 1
-
Ogawa N. Dopamine neurotransmission and treatments for Parkinson's disease in the molecular biology era. Eur Neurol 1997; 38(Suppl 1): 2–5.
-
(1997)
Eur Neurol
, vol.38
, pp. 2-5
-
-
Ogawa, N.1
-
27
-
-
84940459255
-
Comparison between alpha-synuclein wild-type and A53T mutation in a progressive Parkinson's disease model
-
Lu J, Sun F, Ma H, Qing H, Deng Y. Comparison between alpha-synuclein wild-type and A53T mutation in a progressive Parkinson's disease model. Biochem Biophys Res Commun 2015; 464: 988–993.
-
(2015)
Biochem Biophys Res Commun
, vol.464
, pp. 988-993
-
-
Lu, J.1
Sun, F.2
Ma, H.3
Qing, H.4
Deng, Y.5
-
28
-
-
58149468381
-
Motor impairment and aberrant production of neurochemicals in human alpha-synuclein A30P+A53T transgenic mice with alpha-synuclein pathology
-
Ikeda M, Kawarabayashi T, Harigaya Y, Sasaki A, Yamada S, Matsubara E et al. Motor impairment and aberrant production of neurochemicals in human alpha-synuclein A30P+A53T transgenic mice with alpha-synuclein pathology. Brain Res 2009; 1250: 232–241.
-
(2009)
Brain Res
, vol.1250
, pp. 232-241
-
-
Ikeda, M.1
Kawarabayashi, T.2
Harigaya, Y.3
Sasaki, A.4
Yamada, S.5
Matsubara, E.6
-
29
-
-
84872458771
-
Aggregation and neurotoxicity of recombinant alpha-synuclein aggregates initiated by dimerization
-
Roostaee A, Beaudoin S, Staskevicius A, Roucou X. Aggregation and neurotoxicity of recombinant alpha-synuclein aggregates initiated by dimerization. Mol Neurodegener 2013; 8: 5.
-
(2013)
Mol Neurodegener
, vol.8
-
-
Roostaee, A.1
Beaudoin, S.2
Staskevicius, A.3
Roucou, X.4
-
30
-
-
67449116584
-
Involvement of multiple protein kinases in cPLA2 phosphorylation, arachidonic acid release, and cell death in in vivo and in vitro models of 1-methyl-4-phenylpyridinium-induced parkinsonism–the possible key role of PKG
-
Chalimoniuk M, Stolecka A, Zieminska E, Stepien A, Langfort J, Strosznajder JB. Involvement of multiple protein kinases in cPLA2 phosphorylation, arachidonic acid release, and cell death in in vivo and in vitro models of 1-methyl-4-phenylpyridinium-induced parkinsonism–the possible key role of PKG. J Neurochem 2009; 110: 307–317.
-
(2009)
J Neurochem
, vol.110
, pp. 307-317
-
-
Chalimoniuk, M.1
Stolecka, A.2
Zieminska, E.3
Stepien, A.4
Langfort, J.5
Strosznajder, J.B.6
-
31
-
-
84866702836
-
alpha-Synuclein in Parkinson's disease. Cold Spring Harb
-
Stefanis L. alpha-Synuclein in Parkinson's disease. Cold Spring Harb Perspect Med 2012; 2: a009399.
-
(2012)
Perspect Med
, vol.2
-
-
Stefanis, L.1
-
32
-
-
84888119924
-
rAAV2/7 vector-mediated overexpression of alpha-synuclein in mouse substantia nigra induces protein aggregation and progressive dose-dependent neurodegeneration
-
Oliveras-Salva M, Van der Perren A, Casadei N, Stroobants S, Nuber S, D'Hooge R et al. rAAV2/7 vector-mediated overexpression of alpha-synuclein in mouse substantia nigra induces protein aggregation and progressive dose-dependent neurodegeneration. Mol Neurodegener 2013; 8: 44.
-
(2013)
Mol Neurodegener
, vol.8
-
-
Oliveras-Salva, M.1
van der Perren, A.2
Casadei, N.3
Stroobants, S.4
Nuber, S.5
D'hooge, R.6
-
33
-
-
84878264214
-
Conformational templating of alpha-synuclein aggregates in neuronal-glial cultures
-
Sacino AN, Thomas MA, Ceballos-Diaz C, Cruz PE, Rosario AM, Lewis J et al. Conformational templating of alpha-synuclein aggregates in neuronal-glial cultures. Mol Neurodegener 2013; 8: 17.
-
(2013)
Mol Neurodegener
, vol.8
-
-
Sacino, A.N.1
Thomas, M.A.2
Ceballos-Diaz, C.3
Cruz, P.E.4
Rosario, A.M.5
Lewis, J.6
-
34
-
-
84942860108
-
Evidence for alpha-synuclein prions causing multiple system atrophy in humans with parkinsonism
-
Prusiner SB, Woerman AL, Mordes DA, Watts JC, Rampersaud R, Berry DB et al. Evidence for alpha-synuclein prions causing multiple system atrophy in humans with parkinsonism. Proc Natl Acad Sci USA 2015; 112: E5308–E5317.
-
(2015)
Proc Natl Acad Sci USA
, vol.112
-
-
Prusiner, S.B.1
Woerman, A.L.2
Mordes, D.A.3
Watts, J.C.4
Rampersaud, R.5
Berry, D.B.6
-
35
-
-
79960784323
-
Features of microglia and neuroinflammation relevant to environmental exposure and neurotoxicity
-
Kraft AD, Harry GJ. Features of microglia and neuroinflammation relevant to environmental exposure and neurotoxicity. Int J Environ Res Public Health 2011; 8: 2980–3018.
-
(2011)
Int J Environ Res Public Health
, vol.8
, pp. 2980-3018
-
-
Kraft, A.D.1
Harry, G.J.2
-
36
-
-
24144453087
-
Microglia and inflammation-mediated neurodegeneration: Multiple triggers with a common mechanism
-
Block ML, Hong JS. Microglia and inflammation-mediated neurodegeneration: multiple triggers with a common mechanism. Prog Neurobiol 2005; 76: 77–98.
-
(2005)
Prog Neurobiol
, vol.76
, pp. 77-98
-
-
Block, M.L.1
Hong, J.S.2
-
37
-
-
0023789193
-
Reactive microglia are positive for HLA-DR in the substantia nigra of Parkinson's and Alzheimer's disease brains
-
McGeer PL, Itagaki S, Boyes BE, McGeer EG. Reactive microglia are positive for HLA-DR in the substantia nigra of Parkinson's and Alzheimer's disease brains. Neurology 1988; 38: 1285–1291.
-
(1988)
Neurology
, vol.38
, pp. 1285-1291
-
-
McGeer, P.L.1
Itagaki, S.2
Boyes, B.E.3
McGeer, E.G.4
-
38
-
-
70350558453
-
Identification of two distinct macrophage subsets with divergent effects causing either neurotoxicity or regeneration in the injured mouse spinal cord
-
Kigerl KA, Gensel JC, Ankeny DP, Alexander JK, Donnelly DJ, Popovich PG. Identification of two distinct macrophage subsets with divergent effects causing either neurotoxicity or regeneration in the injured mouse spinal cord. JNeurosci2009; 29: 13435–13444.
-
(2009)
Jneurosci
, vol.29
, pp. 13435-13444
-
-
Kigerl, K.A.1
Gensel, J.C.2
Ankeny, D.P.3
Alexander, J.K.4
Donnelly, D.J.5
Popovich, P.G.6
-
39
-
-
79959379095
-
Repertoire of microglial and macrophage responses after spinal cord injury
-
David S, Kroner A. Repertoire of microglial and macrophage responses after spinal cord injury. Nat Rev Neurosci 2011; 12: 388–399.
-
(2011)
Nat Rev Neurosci
, vol.12
, pp. 388-399
-
-
David, S.1
Kroner, A.2
-
40
-
-
84902549638
-
Neuroinflammation and M2 microglia: The good, the bad, and the inflamed
-
Cherry JD, Olschowka JA, O'Banion MK. Neuroinflammation and M2 microglia: the good, the bad, and the inflamed. J Neuroinflammation 2014; 11: 98.
-
(2014)
J Neuroinflammation
, vol.11
-
-
Cherry, J.D.1
Olschowka, J.A.2
O'banion, M.K.3
-
42
-
-
58149216131
-
Inflammatory response in the hippocampus of PS1M146L/APP751SL mouse model of Alzheimer's disease: Age-dependent switch in the microglial phenotype from alternative to classic
-
Jimenez S, Baglietto-Vargas D, Caballero C, Moreno-Gonzalez I, Torres M, Sanchez-Varo R et al. Inflammatory response in the hippocampus of PS1M146L/APP751SL mouse model of Alzheimer's disease: age-dependent switch in the microglial phenotype from alternative to classic. JNeurosci2008; 28: 11650–11661.
-
(2008)
Jneurosci
, vol.28
, pp. 11650-11661
-
-
Jimenez, S.1
Baglietto-Vargas, D.2
Caballero, C.3
Moreno-Gonzalez, I.4
Torres, M.5
Sanchez-Varo, R.6
-
43
-
-
84940796997
-
Phospholipase A2 inhibits cisplatin-induced acute kidney injury by modulating regulatory T cells by the CD206 mannose receptor
-
Kim H, Lee H, Lee G, Jang H, Kim SS, Yoon H et al. Phospholipase A2 inhibits cisplatin-induced acute kidney injury by modulating regulatory T cells by the CD206 mannose receptor. Kidney Int 2015; 88: 550–559.
-
(2015)
Kidney Int
, vol.88
, pp. 550-559
-
-
Kim, H.1
Lee, H.2
Lee, G.3
Jang, H.4
Kim, S.S.5
Yoon, H.6
-
44
-
-
84946603009
-
Bee venom phospholipase A2, a novel Foxp3+ regulatory T cell inducer, protects dopaminergic neurons by modulating neuroinflammatory responses in a mouse model of Parkinson's Disease
-
Chung ES, Lee G, Lee C, Ye M, Chung HS, Kim H et al. Bee venom phospholipase A2, a novel Foxp3+ regulatory T cell inducer, protects dopaminergic neurons by modulating neuroinflammatory responses in a mouse model of Parkinson's Disease. J Immunol 2015; 195: 4853–4860.
-
(2015)
J Immunol
, vol.195
, pp. 4853-4860
-
-
Chung, E.S.1
Lee, G.2
Lee, C.3
Ye, M.4
Chung, H.S.5
Kim, H.6
|