Phospholipase A2 inhibits cisplatin-induced acute kidney injury by modulating regulatory T cells by the CD206 mannose receptor

Kidney International

Volumn 88, Issue 3, 2015, Pages 550-559

  Kim, Hyunseong ^a   Lee, Hyojung ^a   Lee, Gihyun ^a   Jang, Hyunil ^a   Kim, Sung Su ^b   Yoon, Heera ^a   Kang, Geun Hyung ^a   Hwang, Deok Sang ^a   Kim, Sun Kwang ^a   Chung, Hwan Suck ^a   Bae, Hyunsu ^a  

^a Kyung Hee University   (South Korea)

^b Soram Korean Medicine Hospital   (South Korea)

Author keywords

CD206; cisplatin; IL 10; nephrotoxicity; PLA2; regulatory T cells

Indexed keywords

CD206 MANNOSE RECEPTOR; CISPLATIN; CREATININE; GLYCOPROTEIN P 15095; INTERLEUKIN 10; MANNOSE RECEPTOR; NITROGEN; PHOSPHOLIPASE A2; TRANSCRIPTION FACTOR FOXP3; UNCLASSIFIED DRUG; UREA; ANTIINFLAMMATORY AGENT; ANTINEOPLASTIC AGENT; AUTACOID; CELL SURFACE RECEPTOR; IL10 PROTEIN, MOUSE; LECTIN; MANNOSE BINDING LECTIN; PROTEIN BINDING;

ACUTE KIDNEY FAILURE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL INFILTRATION; CONTROLLED STUDY; CREATININE BLOOD LEVEL; CYTOKINE PRODUCTION; DENDRITIC CELL; DRUG MECHANISM; DRUG PROTEIN BINDING; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE; RENAL PROTECTION; T CELL DEPLETION; T LYMPHOCYTE SUBPOPULATION; TISSUE INJURY; ACUTE KIDNEY INJURY; ANIMAL; C57BL MOUSE; CELL CULTURE; CELL PROTECTION; CHEMICALLY INDUCED; DEFICIENCY; DISEASE MODEL; DOSE RESPONSE; DRUG EFFECTS; ENZYMOLOGY; GENETICS; IMMUNOLOGY; KIDNEY; KNOCKOUT MOUSE; LYMPHOCYTE ACTIVATION; LYMPHOMA; METABOLISM; PATHOLOGY; SIGNAL TRANSDUCTION; TIME FACTOR;

ACUTE KIDNEY INJURY; ANIMALS; ANTI-INFLAMMATORY AGENTS; ANTINEOPLASTIC AGENTS; CELLS, CULTURED; CISPLATIN; CYTOPROTECTION; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; INFLAMMATION MEDIATORS; INTERLEUKIN-10; KIDNEY; LECTINS, C-TYPE; LYMPHOCYTE ACTIVATION; LYMPHOMA; MALE; MANNOSE-BINDING LECTINS; MICE, INBRED C57BL; MICE, KNOCKOUT; PHOSPHOLIPASES A2; PROTEIN BINDING; RECEPTORS, CELL SURFACE; SIGNAL TRANSDUCTION; T-LYMPHOCYTES, REGULATORY; TIME FACTORS;

EID: 84940796997     PISSN: 00852538     EISSN: 15231755     Source Type: Journal    
DOI: 10.1038/ki.2015.147     Document Type: Article

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