-
1
-
-
84879384673
-
Novel cellular therapies for leukemia: CAR-modified T cells targeted to the CD19 antigen
-
Brentjens, R.J., Curran, K.J., Novel cellular therapies for leukemia: CAR-modified T cells targeted to the CD19 antigen. Hematology Am Soc Hematol Educ Program 2012 (2012), 143–151.
-
(2012)
Hematology Am Soc Hematol Educ Program
, vol.2012
, pp. 143-151
-
-
Brentjens, R.J.1
Curran, K.J.2
-
2
-
-
84958765641
-
Current status and regulatory perspective of chimeric antigen receptor-modified T cell therapeutics
-
Kim, M.G., Kim, D., Suh, S.K., Park, Z., Choi, M.J., Oh, Y.K., Current status and regulatory perspective of chimeric antigen receptor-modified T cell therapeutics. Arch Pharm Res 39 (2016), 437–452.
-
(2016)
Arch Pharm Res
, vol.39
, pp. 437-452
-
-
Kim, M.G.1
Kim, D.2
Suh, S.K.3
Park, Z.4
Choi, M.J.5
Oh, Y.K.6
-
3
-
-
79955517235
-
CD28 costimulation improves expansion and persistence of chimeric antigen receptor-modified T cells in lymphoma patients
-
Savoldo, B., Ramos, C.A., Liu, E., et al. CD28 costimulation improves expansion and persistence of chimeric antigen receptor-modified T cells in lymphoma patients. J Clin Invest 121 (2011), 1822–1826.
-
(2011)
J Clin Invest
, vol.121
, pp. 1822-1826
-
-
Savoldo, B.1
Ramos, C.A.2
Liu, E.3
-
4
-
-
76349087378
-
Chimeric antigen receptors combining 4-1BB and CD28 signaling domains augment PI3kinase/AKT/Bcl-XL activation and CD8+ T cell-mediated tumor eradication
-
Zhong, X.S., Matsushita, M., Plotkin, J., Riviere, I., Sadelain, M., Chimeric antigen receptors combining 4-1BB and CD28 signaling domains augment PI3kinase/AKT/Bcl-XL activation and CD8+ T cell-mediated tumor eradication. Mol Ther 18 (2010), 413–420.
-
(2010)
Mol Ther
, vol.18
, pp. 413-420
-
-
Zhong, X.S.1
Matsushita, M.2
Plotkin, J.3
Riviere, I.4
Sadelain, M.5
-
5
-
-
84940881287
-
Chimeric antigen receptor T cells persist and induce sustained remissions in relapsed refractory chronic lymphocytic leukemia
-
Porter, D.L., Hwang, W.T., Frey, N.V., et al. Chimeric antigen receptor T cells persist and induce sustained remissions in relapsed refractory chronic lymphocytic leukemia. Sci Transl Med, 7, 2015, 303ra139.
-
(2015)
Sci Transl Med
, vol.7
, pp. 303ra139
-
-
Porter, D.L.1
Hwang, W.T.2
Frey, N.V.3
-
6
-
-
84863337890
-
B-cell depletion and remissions of malignancy along with cytokine-associated toxicity in a clinical trial of anti-CD19 chimeric-antigen-receptor-transduced T cells
-
Kochenderfer, J.N., Dudley, M.E., Feldman, S.A., et al. B-cell depletion and remissions of malignancy along with cytokine-associated toxicity in a clinical trial of anti-CD19 chimeric-antigen-receptor-transduced T cells. Blood 119 (2012), 2709–2720.
-
(2012)
Blood
, vol.119
, pp. 2709-2720
-
-
Kochenderfer, J.N.1
Dudley, M.E.2
Feldman, S.A.3
-
7
-
-
80455179612
-
Safety and persistence of adoptively transferred autologous CD19-targeted T cells in patients with relapsed or chemotherapy refractory B-cell leukemias
-
Brentjens, R.J., Riviere, I., Park, J.H., et al. Safety and persistence of adoptively transferred autologous CD19-targeted T cells in patients with relapsed or chemotherapy refractory B-cell leukemias. Blood 118 (2011), 4817–4828.
-
(2011)
Blood
, vol.118
, pp. 4817-4828
-
-
Brentjens, R.J.1
Riviere, I.2
Park, J.H.3
-
8
-
-
84969244099
-
Toxicity and management in CAR T-cell therapy
-
Bonifant, C.L., Jackson, H.J., Brentjens, R.J., Curran, K.J., Toxicity and management in CAR T-cell therapy. Mol Ther Oncolytics, 3, 2016, 16011.
-
(2016)
Mol Ther Oncolytics
, vol.3
, pp. 16011
-
-
Bonifant, C.L.1
Jackson, H.J.2
Brentjens, R.J.3
Curran, K.J.4
-
9
-
-
84924693659
-
Challenges to chimeric antigen receptor (CAR)-T cell therapy for cancer
-
Magee, M.S., Snook, A.E., Challenges to chimeric antigen receptor (CAR)-T cell therapy for cancer. Discov Med 18 (2014), 265–271.
-
(2014)
Discov Med
, vol.18
, pp. 265-271
-
-
Magee, M.S.1
Snook, A.E.2
-
10
-
-
33646877669
-
Human natural killer cell development and biology
-
Farag, S.S., Caligiuri, M.A., Human natural killer cell development and biology. Blood Rev 20 (2006), 123–137.
-
(2006)
Blood Rev
, vol.20
, pp. 123-137
-
-
Farag, S.S.1
Caligiuri, M.A.2
-
11
-
-
11144299492
-
NK cell recognition
-
Lanier, L.L., NK cell recognition. Annu Rev Immunol 23 (2005), 225–274.
-
(2005)
Annu Rev Immunol
, vol.23
, pp. 225-274
-
-
Lanier, L.L.1
-
12
-
-
0035874522
-
Human natural killer cells: a unique innate immunoregulatory role for the CD56(bright) subset
-
Cooper, M.A., Fehniger, T.A., Turner, S.C., et al. Human natural killer cells: a unique innate immunoregulatory role for the CD56(bright) subset. Blood 97 (2001), 3146–3151.
-
(2001)
Blood
, vol.97
, pp. 3146-3151
-
-
Cooper, M.A.1
Fehniger, T.A.2
Turner, S.C.3
-
13
-
-
33745567831
-
Self-tolerance of natural killer cells
-
Raulet, D.H., Vance, R.E., Self-tolerance of natural killer cells. Nat Rev Immunol 6 (2006), 520–531.
-
(2006)
Nat Rev Immunol
, vol.6
, pp. 520-531
-
-
Raulet, D.H.1
Vance, R.E.2
-
14
-
-
42449102990
-
Up on the tightrope: natural killer cell activation and inhibition
-
Lanier, L.L., Up on the tightrope: natural killer cell activation and inhibition. Nat Immunol 9 (2008), 495–502.
-
(2008)
Nat Immunol
, vol.9
, pp. 495-502
-
-
Lanier, L.L.1
-
15
-
-
84894339689
-
Activating killer cell immunoglobulin-like receptor 2DS2 binds to HLA-A*11
-
Liu, J., Xiao, Z., Ko, H.L., Shen, M., Ren, E.C., Activating killer cell immunoglobulin-like receptor 2DS2 binds to HLA-A*11. Proc Natl Acad Sci U S A 111 (2014), 2662–2667.
-
(2014)
Proc Natl Acad Sci U S A
, vol.111
, pp. 2662-2667
-
-
Liu, J.1
Xiao, Z.2
Ko, H.L.3
Shen, M.4
Ren, E.C.5
-
16
-
-
77950408682
-
Regulation of human NK-cell cytokine and chemokine production by target cell recognition
-
Fauriat, C., Long, E.O., Ljunggren, H.G., Bryceson, Y.T., Regulation of human NK-cell cytokine and chemokine production by target cell recognition. Blood 115 (2010), 2167–2176.
-
(2010)
Blood
, vol.115
, pp. 2167-2176
-
-
Fauriat, C.1
Long, E.O.2
Ljunggren, H.G.3
Bryceson, Y.T.4
-
17
-
-
0142197631
-
Roles of the NKG2D immunoreceptor and its ligands
-
Raulet, D.H., Roles of the NKG2D immunoreceptor and its ligands. Nat Rev Immunol 3 (2003), 781–790.
-
(2003)
Nat Rev Immunol
, vol.3
, pp. 781-790
-
-
Raulet, D.H.1
-
18
-
-
84955312560
-
Selection and expansion of natural killer cells for NK cell-based immunotherapy
-
Becker, P.S., Suck, G., Nowakowska, P., et al. Selection and expansion of natural killer cells for NK cell-based immunotherapy. Cancer Immunol Immunother 65 (2016), 477–484.
-
(2016)
Cancer Immunol Immunother
, vol.65
, pp. 477-484
-
-
Becker, P.S.1
Suck, G.2
Nowakowska, P.3
-
19
-
-
0346339806
-
Purification of human natural killer cells using a clinical-scale immunomagnetic method
-
Iyengar, R., Handgretinger, R., Babarin-Dorner, A., et al. Purification of human natural killer cells using a clinical-scale immunomagnetic method. Cytotherapy 5 (2003), 479–484.
-
(2003)
Cytotherapy
, vol.5
, pp. 479-484
-
-
Iyengar, R.1
Handgretinger, R.2
Babarin-Dorner, A.3
-
20
-
-
84891101533
-
Clinical grade purification and expansion of NK cell products for an optimized manufacturing protocol
-
Koehl, U., Brehm, C., Huenecke, S., et al. Clinical grade purification and expansion of NK cell products for an optimized manufacturing protocol. Front Oncol, 3, 2013, 118.
-
(2013)
Front Oncol
, vol.3
, pp. 118
-
-
Koehl, U.1
Brehm, C.2
Huenecke, S.3
-
21
-
-
78649303217
-
Clinical-grade, large-scale, feeder-free expansion of highly active human natural killer cells for adoptive immunotherapy using an automated bioreactor
-
Sutlu, T., Stellan, B., Gilljam, M., et al. Clinical-grade, large-scale, feeder-free expansion of highly active human natural killer cells for adoptive immunotherapy using an automated bioreactor. Cytotherapy 12 (2010), 1044–1055.
-
(2010)
Cytotherapy
, vol.12
, pp. 1044-1055
-
-
Sutlu, T.1
Stellan, B.2
Gilljam, M.3
-
22
-
-
84902682889
-
Clearance of acute myeloid leukemia by haploidentical natural killer cells is improved using IL-2 diphtheria toxin fusion protein
-
Bachanova, V., Cooley, S., Defor, T.E., et al. Clearance of acute myeloid leukemia by haploidentical natural killer cells is improved using IL-2 diphtheria toxin fusion protein. Blood 123 (2014), 3855–3863.
-
(2014)
Blood
, vol.123
, pp. 3855-3863
-
-
Bachanova, V.1
Cooley, S.2
Defor, T.E.3
-
23
-
-
78650970845
-
Innate or adaptive immunity? The example of natural killer cells
-
Vivier, E., Raulet, D.H., Moretta, A., et al. Innate or adaptive immunity? The example of natural killer cells. Science 331 (2011), 44–49.
-
(2011)
Science
, vol.331
, pp. 44-49
-
-
Vivier, E.1
Raulet, D.H.2
Moretta, A.3
-
24
-
-
33845199637
-
Perforin-mediated target-cell death and immune homeostasis
-
Voskoboinik, I., Smyth, M.J., Trapani, J.A., Perforin-mediated target-cell death and immune homeostasis. Nat Rev Immunol 6 (2006), 940–952.
-
(2006)
Nat Rev Immunol
, vol.6
, pp. 940-952
-
-
Voskoboinik, I.1
Smyth, M.J.2
Trapani, J.A.3
-
25
-
-
0035881578
-
A central role for death receptor-mediated apoptosis in the rejection of tumors by NK cells
-
Screpanti, V., Wallin, R.P., Ljunggren, H.G., Grandien, A., A central role for death receptor-mediated apoptosis in the rejection of tumors by NK cells. J Immunol 167 (2001), 2068–2073.
-
(2001)
J Immunol
, vol.167
, pp. 2068-2073
-
-
Screpanti, V.1
Wallin, R.P.2
Ljunggren, H.G.3
Grandien, A.4
-
26
-
-
1542359024
-
The beneficial role of inhibitory KIR genes of HLA class I NK epitopes in haploidentically mismatched stem cell allografts may be masked by residual donor-alloreactive T cells causing GVHD
-
Bishara, A., De Santis, D., Witt, C.C., et al. The beneficial role of inhibitory KIR genes of HLA class I NK epitopes in haploidentically mismatched stem cell allografts may be masked by residual donor-alloreactive T cells causing GVHD. Tissue Antigens 63 (2004), 204–211.
-
(2004)
Tissue Antigens
, vol.63
, pp. 204-211
-
-
Bishara, A.1
De Santis, D.2
Witt, C.C.3
-
27
-
-
36549023879
-
NK cell alloreactivity and allogeneic hematopoietic stem cell transplantation
-
Ruggeri, L., Mancusi, A., Burchielli, E., et al. NK cell alloreactivity and allogeneic hematopoietic stem cell transplantation. Blood Cells Mol Dis 40 (2008), 84–90.
-
(2008)
Blood Cells Mol Dis
, vol.40
, pp. 84-90
-
-
Ruggeri, L.1
Mancusi, A.2
Burchielli, E.3
-
28
-
-
84902590288
-
Are natural killer cells superior CAR drivers?
-
Klingemann, H., Are natural killer cells superior CAR drivers?. Oncoimmunology, 3, 2014, e28147.
-
(2014)
Oncoimmunology
, vol.3
, pp. e28147
-
-
Klingemann, H.1
-
29
-
-
23644458333
-
Licensing of natural killer cells by host major histocompatibility complex class I molecules
-
Kim, S., Poursine-Laurent, J., Truscott, S.M., et al. Licensing of natural killer cells by host major histocompatibility complex class I molecules. Nature 436 (2005), 709–713.
-
(2005)
Nature
, vol.436
, pp. 709-713
-
-
Kim, S.1
Poursine-Laurent, J.2
Truscott, S.M.3
-
30
-
-
20144388509
-
Successful adoptive transfer and in vivo expansion of human haploidentical NK cells in patients with cancer
-
Miller, J.S., Soignier, Y., Panoskaltsis-Mortari, A., et al. Successful adoptive transfer and in vivo expansion of human haploidentical NK cells in patients with cancer. Blood 105 (2005), 3051–3057.
-
(2005)
Blood
, vol.105
, pp. 3051-3057
-
-
Miller, J.S.1
Soignier, Y.2
Panoskaltsis-Mortari, A.3
-
31
-
-
22044456688
-
Genetic modification of primary natural killer cells overcomes inhibitory signals and induces specific killing of leukemic cells
-
Imai, C., Iwamoto, S., Campana, D., Genetic modification of primary natural killer cells overcomes inhibitory signals and induces specific killing of leukemic cells. Blood 106 (2005), 376–383.
-
(2005)
Blood
, vol.106
, pp. 376-383
-
-
Imai, C.1
Iwamoto, S.2
Campana, D.3
-
32
-
-
84863915982
-
A clinically adaptable method to enhance the cytotoxicity of natural killer cells against B-cell malignancies
-
Shimasaki, N., Fujisaki, H., Cho, D., et al. A clinically adaptable method to enhance the cytotoxicity of natural killer cells against B-cell malignancies. Cytotherapy 14 (2012), 830–840.
-
(2012)
Cytotherapy
, vol.14
, pp. 830-840
-
-
Shimasaki, N.1
Fujisaki, H.2
Cho, D.3
-
33
-
-
84934281880
-
Targeting CD20+ aggressive B-cell non-Hodgkin lymphoma by anti-CD20 CAR mRNA-Modified expanded natural killer cells in vitro and in NSG mice
-
Chu, Y., Hochberg, J., Yahr, A., et al. Targeting CD20+ aggressive B-cell non-Hodgkin lymphoma by anti-CD20 CAR mRNA-Modified expanded natural killer cells in vitro and in NSG mice. Cancer Immunol Res 3 (2015), 333–344.
-
(2015)
Cancer Immunol Res
, vol.3
, pp. 333-344
-
-
Chu, Y.1
Hochberg, J.2
Yahr, A.3
-
34
-
-
68049142423
-
2B4 (CD244) signaling by recombinant antigen-specific chimeric receptors costimulates natural killer cell activation to leukemia and neuroblastoma cells
-
Altvater, B., Landmeier, S., Pscherer, S., et al. 2B4 (CD244) signaling by recombinant antigen-specific chimeric receptors costimulates natural killer cell activation to leukemia and neuroblastoma cells. Clin Cancer Res 15 (2009), 4857–4866.
-
(2009)
Clin Cancer Res
, vol.15
, pp. 4857-4866
-
-
Altvater, B.1
Landmeier, S.2
Pscherer, S.3
-
35
-
-
56249128626
-
Engineering antigen-specific primary human NK cells against HER-2 positive carcinomas
-
Kruschinski, A., Moosmann, A., Poschke, I., et al. Engineering antigen-specific primary human NK cells against HER-2 positive carcinomas. Proc Natl Acad Sci U S A 105 (2008), 17481–17486.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 17481-17486
-
-
Kruschinski, A.1
Moosmann, A.2
Poschke, I.3
-
36
-
-
84875469893
-
A chimeric receptor with NKG2D specificity enhances natural killer cell activation and killing of tumor cells
-
Chang, Y.H., Connolly, J., Shimasaki, N., Mimura, K., Kono, K., Campana, D., A chimeric receptor with NKG2D specificity enhances natural killer cell activation and killing of tumor cells. Cancer Res 73 (2013), 1777–1786.
-
(2013)
Cancer Res
, vol.73
, pp. 1777-1786
-
-
Chang, Y.H.1
Connolly, J.2
Shimasaki, N.3
Mimura, K.4
Kono, K.5
Campana, D.6
-
37
-
-
77649139885
-
IL-2-driven regulation of NK cell receptors with regard to the distribution of CD16+ and CD16- subpopulations and in vivo influence after haploidentical NK cell infusion
-
Huenecke, S., Zimmermann, S.Y., Kloess, S., et al. IL-2-driven regulation of NK cell receptors with regard to the distribution of CD16+ and CD16- subpopulations and in vivo influence after haploidentical NK cell infusion. J Immunother 33 (2010), 200–210.
-
(2010)
J Immunother
, vol.33
, pp. 200-210
-
-
Huenecke, S.1
Zimmermann, S.Y.2
Kloess, S.3
-
38
-
-
48549099675
-
Serial killing of tumor cells by human natural killer cells–enhancement by therapeutic antibodies
-
Bhat, R., Watzl, C., Serial killing of tumor cells by human natural killer cells–enhancement by therapeutic antibodies. PLoS One, 2, 2007, e326.
-
(2007)
PLoS One
, vol.2
, pp. e326
-
-
Bhat, R.1
Watzl, C.2
-
39
-
-
80655128594
-
IL-2 stimulated but not unstimulated NK cells induce selective disappearance of peripheral blood cells: concomitant results to a phase I/II study
-
Brehm, C., Huenecke, S., Quaiser, A., et al. IL-2 stimulated but not unstimulated NK cells induce selective disappearance of peripheral blood cells: concomitant results to a phase I/II study. PLoS One, 6, 2011, e27351.
-
(2011)
PLoS One
, vol.6
, pp. e27351
-
-
Brehm, C.1
Huenecke, S.2
Quaiser, A.3
-
40
-
-
84887052348
-
Treatment of patients with advanced cancer with the natural killer cell line NK-92
-
Tonn, T., Schwabe, D., Klingemann, H.G., et al. Treatment of patients with advanced cancer with the natural killer cell line NK-92. Cytotherapy 15 (2013), 1563–1570.
-
(2013)
Cytotherapy
, vol.15
, pp. 1563-1570
-
-
Tonn, T.1
Schwabe, D.2
Klingemann, H.G.3
-
41
-
-
0034924584
-
Factors regulating the cytotoxic activity of the human natural killer cell line, NK-92
-
Maki, G., Klingemann, H.G., Martinson, J.A., Tam, Y.K., Factors regulating the cytotoxic activity of the human natural killer cell line, NK-92. J Hematother Stem Cell Res 10 (2001), 369–383.
-
(2001)
J Hematother Stem Cell Res
, vol.10
, pp. 369-383
-
-
Maki, G.1
Klingemann, H.G.2
Martinson, J.A.3
Tam, Y.K.4
-
42
-
-
0038353371
-
Immunoprofiling of cell lines derived from natural killer-cell and natural killer-like T-cell leukemia-lymphoma
-
Matsuo, Y., Drexler, H.G., Immunoprofiling of cell lines derived from natural killer-cell and natural killer-like T-cell leukemia-lymphoma. Leuk Res 27 (2003), 935–945.
-
(2003)
Leuk Res
, vol.27
, pp. 935-945
-
-
Matsuo, Y.1
Drexler, H.G.2
-
43
-
-
84864879299
-
Natural killer cell lines in tumor immunotherapy
-
Cheng, M., Zhang, J., Jiang, W., Chen, Y., Tian, Z., Natural killer cell lines in tumor immunotherapy. Front Med 6 (2012), 56–66.
-
(2012)
Front Med
, vol.6
, pp. 56-66
-
-
Cheng, M.1
Zhang, J.2
Jiang, W.3
Chen, Y.4
Tian, Z.5
-
44
-
-
37349039692
-
Expression of a CD20-specific chimeric antigen receptor enhances cytotoxic activity of NK cells and overcomes NK-resistance of lymphoma and leukemia cells
-
Muller, T., Uherek, C., Maki, G., et al. Expression of a CD20-specific chimeric antigen receptor enhances cytotoxic activity of NK cells and overcomes NK-resistance of lymphoma and leukemia cells. Cancer Immunol Immunother 57 (2008), 411–423.
-
(2008)
Cancer Immunol Immunother
, vol.57
, pp. 411-423
-
-
Muller, T.1
Uherek, C.2
Maki, G.3
-
45
-
-
84859990187
-
Comparison of mRNA and lentiviral based transfection of natural killer cells with chimeric antigen receptors recognizing lymphoid antigens
-
Boissel, L., Betancur, M., Lu, W., et al. Comparison of mRNA and lentiviral based transfection of natural killer cells with chimeric antigen receptors recognizing lymphoid antigens. Leuk Lymphoma 53 (2012), 958–965.
-
(2012)
Leuk Lymphoma
, vol.53
, pp. 958-965
-
-
Boissel, L.1
Betancur, M.2
Lu, W.3
-
46
-
-
84902582355
-
Retargeting NK-92 cells by means of CD19- and CD20-specific chimeric antigen receptors compares favorably with antibody-dependent cellular cytotoxicity
-
Boissel, L., Betancur-Boissel, M., Lu, W., et al. Retargeting NK-92 cells by means of CD19- and CD20-specific chimeric antigen receptors compares favorably with antibody-dependent cellular cytotoxicity. Oncoimmunology, 2, 2013, e26527.
-
(2013)
Oncoimmunology
, vol.2
, pp. e26527
-
-
Boissel, L.1
Betancur-Boissel, M.2
Lu, W.3
-
47
-
-
0037103311
-
Retargeting of natural killer-cell cytolytic activity to ErbB2-expressing cancer cells results in efficient and selective tumor cell destruction
-
Uherek, C., Tonn, T., Uherek, B., et al. Retargeting of natural killer-cell cytolytic activity to ErbB2-expressing cancer cells results in efficient and selective tumor cell destruction. Blood 100 (2002), 1265–1273.
-
(2002)
Blood
, vol.100
, pp. 1265-1273
-
-
Uherek, C.1
Tonn, T.2
Uherek, B.3
-
48
-
-
84916211311
-
Specific growth inhibition of ErbB2expressing human breast cancer cells by genetically modified NK92 cells
-
Liu, H., Yang, B., Sun, T., et al. Specific growth inhibition of ErbB2expressing human breast cancer cells by genetically modified NK92 cells. Oncol Rep 33 (2015), 95–102.
-
(2015)
Oncol Rep
, vol.33
, pp. 95-102
-
-
Liu, H.1
Yang, B.2
Sun, T.3
-
49
-
-
84922257867
-
Selective inhibition of tumor growth by clonal NK cells expressing an ErbB2/HER2-specific chimeric antigen receptor
-
Schonfeld, K., Sahm, C., Zhang, C., et al. Selective inhibition of tumor growth by clonal NK cells expressing an ErbB2/HER2-specific chimeric antigen receptor. Mol Ther 23 (2015), 330–338.
-
(2015)
Mol Ther
, vol.23
, pp. 330-338
-
-
Schonfeld, K.1
Sahm, C.2
Zhang, C.3
-
50
-
-
84856267795
-
NK cells engineered to express a GD2 -specific antigen receptor display built-in ADCC-like activity against tumour cells of neuroectodermal origin
-
Esser, R., Muller, T., Stefes, D., et al. NK cells engineered to express a GD2 -specific antigen receptor display built-in ADCC-like activity against tumour cells of neuroectodermal origin. J Cell Mol Med 16 (2012), 569–581.
-
(2012)
J Cell Mol Med
, vol.16
, pp. 569-581
-
-
Esser, R.1
Muller, T.2
Stefes, D.3
-
51
-
-
84894325649
-
Transfection of chimeric anti-CD138 gene enhances natural killer cell activation and killing of multiple myeloma cells
-
Jiang, H., Zhang, W., Shang, P., et al. Transfection of chimeric anti-CD138 gene enhances natural killer cell activation and killing of multiple myeloma cells. Mol Oncol 8 (2014), 297–310.
-
(2014)
Mol Oncol
, vol.8
, pp. 297-310
-
-
Jiang, H.1
Zhang, W.2
Shang, P.3
-
52
-
-
84866541747
-
Expression of IL-15 in NK cells results in rapid enrichment and selective cytotoxicity of gene-modified effectors that carry a tumor-specific antigen receptor
-
Sahm, C., Schonfeld, K., Wels, W.S., Expression of IL-15 in NK cells results in rapid enrichment and selective cytotoxicity of gene-modified effectors that carry a tumor-specific antigen receptor. Cancer Immunol Immunother 61 (2012), 1451–1461.
-
(2012)
Cancer Immunol Immunother
, vol.61
, pp. 1451-1461
-
-
Sahm, C.1
Schonfeld, K.2
Wels, W.S.3
-
53
-
-
84855944650
-
Retargeting NK92 cells using an HLA-A2-restricted, EBNA3C-specific chimeric antigen receptor
-
Tassev, D.V., Cheng, M., Cheung, N.K., Retargeting NK92 cells using an HLA-A2-restricted, EBNA3C-specific chimeric antigen receptor. Cancer Gene Ther 19 (2012), 84–100.
-
(2012)
Cancer Gene Ther
, vol.19
, pp. 84-100
-
-
Tassev, D.V.1
Cheng, M.2
Cheung, N.K.3
-
54
-
-
84898461706
-
CS1-specific chimeric antigen receptor (CAR)-engineered natural killer cells enhance in vitro and in vivo antitumor activity against human multiple myeloma
-
Chu, J., Deng, Y., Benson, D.M., et al. CS1-specific chimeric antigen receptor (CAR)-engineered natural killer cells enhance in vitro and in vivo antitumor activity against human multiple myeloma. Leukemia 28 (2014), 917–927.
-
(2014)
Leukemia
, vol.28
, pp. 917-927
-
-
Chu, J.1
Deng, Y.2
Benson, D.M.3
-
55
-
-
0031930432
-
Absence of B7.1-CD28/CTLA-4-mediated co-stimulation in human NK cells
-
Lang, S., Vujanovic, N.L., Wollenberg, B., Whiteside, T.L., Absence of B7.1-CD28/CTLA-4-mediated co-stimulation in human NK cells. Eur J Immunol 28 (1998), 780–786.
-
(1998)
Eur J Immunol
, vol.28
, pp. 780-786
-
-
Lang, S.1
Vujanovic, N.L.2
Wollenberg, B.3
Whiteside, T.L.4
-
56
-
-
85006965240
-
Continuously expanding CAR NK-92 cells display selective cytotoxicity against B-cell leukemia and lymphoma
-
Oelsner, S., Friede, M.E., Zhang, C., et al. Continuously expanding CAR NK-92 cells display selective cytotoxicity against B-cell leukemia and lymphoma. Cytotherapy 19 (2017), 235–249.
-
(2017)
Cytotherapy
, vol.19
, pp. 235-249
-
-
Oelsner, S.1
Friede, M.E.2
Zhang, C.3
-
57
-
-
85019981328
-
Preclinical targeting of aggressive T cell malignancies using anti-CD5 chimeric antigen receptor
-
[Epub ahead of print]
-
Chen, K.H., Wada, M., Pinz, K.G., et al. Preclinical targeting of aggressive T cell malignancies using anti-CD5 chimeric antigen receptor. Leukemia, 2017 http://dx.doi.org/10.1038/leu.2017.8 [Epub ahead of print].
-
(2017)
Leukemia
-
-
Chen, K.H.1
Wada, M.2
Pinz, K.G.3
-
58
-
-
47549090432
-
TGFbeta in cancer
-
Massague, J., TGFbeta in cancer. Cell 134 (2008), 215–230.
-
(2008)
Cell
, vol.134
, pp. 215-230
-
-
Massague, J.1
-
59
-
-
84985912326
-
The breast tumor microenvironment alters the phenotype and function of natural killer cells
-
Krneta, T., Gillgrass, A., Chew, M., Ashkar, A.A., The breast tumor microenvironment alters the phenotype and function of natural killer cells. Cell Mol Immunol 13 (2016), 628–639.
-
(2016)
Cell Mol Immunol
, vol.13
, pp. 628-639
-
-
Krneta, T.1
Gillgrass, A.2
Chew, M.3
Ashkar, A.A.4
-
60
-
-
85011890527
-
Augmented anti-tumor activity of NK-92 cells expressing chimeric receptors of TGF-betaR II and NKG2D
-
Wang, Z., Guo, L., Song, Y., et al. Augmented anti-tumor activity of NK-92 cells expressing chimeric receptors of TGF-betaR II and NKG2D. Cancer Immunol Immunother 66 (2017), 537–548.
-
(2017)
Cancer Immunol Immunother
, vol.66
, pp. 537-548
-
-
Wang, Z.1
Guo, L.2
Song, Y.3
-
61
-
-
84878642671
-
Natural killer cell reprogramming with chimeric immune receptors
-
Shimasaki, N., Campana, D., Natural killer cell reprogramming with chimeric immune receptors. Methods Mol Biol 969 (2013), 203–220.
-
(2013)
Methods Mol Biol
, vol.969
, pp. 203-220
-
-
Shimasaki, N.1
Campana, D.2
-
62
-
-
0037134054
-
A thymic precursor to the NK T cell lineage
-
Benlagha, K., Kyin, T., Beavis, A., Teyton, L., Bendelac, A., A thymic precursor to the NK T cell lineage. Science 296 (2002), 553–555.
-
(2002)
Science
, vol.296
, pp. 553-555
-
-
Benlagha, K.1
Kyin, T.2
Beavis, A.3
Teyton, L.4
Bendelac, A.5
-
63
-
-
0034774980
-
NKT cells derive from double-positive thymocytes that are positively selected by CD1d
-
Gapin, L., Matsuda, J.L., Surh, C.D., Kronenberg, M., NKT cells derive from double-positive thymocytes that are positively selected by CD1d. Nat Immunol 2 (2001), 971–978.
-
(2001)
Nat Immunol
, vol.2
, pp. 971-978
-
-
Gapin, L.1
Matsuda, J.L.2
Surh, C.D.3
Kronenberg, M.4
-
64
-
-
20444493969
-
Genetic evidence supporting selection of the Valpha14i NKT cell lineage from double-positive thymocyte precursors
-
Egawa, T., Eberl, G., Taniuchi, I., et al. Genetic evidence supporting selection of the Valpha14i NKT cell lineage from double-positive thymocyte precursors. Immunity 22 (2005), 705–716.
-
(2005)
Immunity
, vol.22
, pp. 705-716
-
-
Egawa, T.1
Eberl, G.2
Taniuchi, I.3
-
65
-
-
0028025074
-
An invariant T cell receptor alpha chain is used by a unique subset of major histocompatibility complex class I-specific CD4+ and CD4-8- T cells in mice and humans
-
Lantz, O., Bendelac, A., An invariant T cell receptor alpha chain is used by a unique subset of major histocompatibility complex class I-specific CD4+ and CD4-8- T cells in mice and humans. J Exp Med 180 (1994), 1097–1106.
-
(1994)
J Exp Med
, vol.180
, pp. 1097-1106
-
-
Lantz, O.1
Bendelac, A.2
-
66
-
-
0037018108
-
Distinct functional lineages of human V(alpha)24 natural killer T cells
-
Lee, P.T., Benlagha, K., Teyton, L., Bendelac, A., Distinct functional lineages of human V(alpha)24 natural killer T cells. J Exp Med 195 (2002), 637–641.
-
(2002)
J Exp Med
, vol.195
, pp. 637-641
-
-
Lee, P.T.1
Benlagha, K.2
Teyton, L.3
Bendelac, A.4
-
67
-
-
0037018101
-
Functionally distinct subsets of CD1d-restricted natural killer T cells revealed by CD1d tetramer staining
-
Gumperz, J.E., Miyake, S., Yamamura, T., Brenner, M.B., Functionally distinct subsets of CD1d-restricted natural killer T cells revealed by CD1d tetramer staining. J Exp Med 195 (2002), 625–636.
-
(2002)
J Exp Med
, vol.195
, pp. 625-636
-
-
Gumperz, J.E.1
Miyake, S.2
Yamamura, T.3
Brenner, M.B.4
-
68
-
-
0029072786
-
CD1: presenting unusual antigens to unusual T lymphocytes
-
Bendelac, A., CD1: presenting unusual antigens to unusual T lymphocytes. Science 269 (1995), 185–186.
-
(1995)
Science
, vol.269
, pp. 185-186
-
-
Bendelac, A.1
-
69
-
-
0032055980
-
CD1.1 expression by mouse antigen-presenting cells and marginal zone B cells
-
Roark, J.H., Park, S.H., Jayawardena, J., Kavita, U., Shannon, M., Bendelac, A., CD1.1 expression by mouse antigen-presenting cells and marginal zone B cells. J Immunol 160 (1998), 3121–3127.
-
(1998)
J Immunol
, vol.160
, pp. 3121-3127
-
-
Roark, J.H.1
Park, S.H.2
Jayawardena, J.3
Kavita, U.4
Shannon, M.5
Bendelac, A.6
-
70
-
-
0030696696
-
CD1d-restricted and TCR-mediated activation of valpha14 NKT cells by glycosylceramides
-
Kawano, T., Cui, J., Koezuka, Y., et al. CD1d-restricted and TCR-mediated activation of valpha14 NKT cells by glycosylceramides. Science 278 (1997), 1626–1629.
-
(1997)
Science
, vol.278
, pp. 1626-1629
-
-
Kawano, T.1
Cui, J.2
Koezuka, Y.3
-
71
-
-
0032744350
-
NKT cells are phenotypically and functionally diverse
-
Hammond, K.J., Pelikan, S.B., Crowe, N.Y., et al. NKT cells are phenotypically and functionally diverse. Eur J Immunol 29 (1999), 3768–3781.
-
(1999)
Eur J Immunol
, vol.29
, pp. 3768-3781
-
-
Hammond, K.J.1
Pelikan, S.B.2
Crowe, N.Y.3
-
72
-
-
23844457565
-
NKT cell stimulation with glycolipid antigen in vivo: costimulation-dependent expansion, Bim-dependent contraction, and hyporesponsiveness to further antigenic challenge
-
Uldrich, A.P., Crowe, N.Y., Kyparissoudis, K., et al. NKT cell stimulation with glycolipid antigen in vivo: costimulation-dependent expansion, Bim-dependent contraction, and hyporesponsiveness to further antigenic challenge. J Immunol 175 (2005), 3092–3101.
-
(2005)
J Immunol
, vol.175
, pp. 3092-3101
-
-
Uldrich, A.P.1
Crowe, N.Y.2
Kyparissoudis, K.3
-
73
-
-
0035873434
-
Differential regulation of Th1 and Th2 functions of NKT cells by CD28 and CD40 costimulatory pathways
-
Hayakawa, Y., Takeda, K., Yagita, H., Van Kaer, L., Saiki, I., Okumura, K., Differential regulation of Th1 and Th2 functions of NKT cells by CD28 and CD40 costimulatory pathways. J Immunol 166 (2001), 6012–6018.
-
(2001)
J Immunol
, vol.166
, pp. 6012-6018
-
-
Hayakawa, Y.1
Takeda, K.2
Yagita, H.3
Van Kaer, L.4
Saiki, I.5
Okumura, K.6
-
74
-
-
2442547655
-
Natural killer T cells infiltrate neuroblastomas expressing the chemokine CCL2
-
Metelitsa, L.S., Wu, H.W., Wang, H., et al. Natural killer T cells infiltrate neuroblastomas expressing the chemokine CCL2. J Exp Med 199 (2004), 1213–1221.
-
(2004)
J Exp Med
, vol.199
, pp. 1213-1221
-
-
Metelitsa, L.S.1
Wu, H.W.2
Wang, H.3
-
75
-
-
27144471372
-
Increased intratumor Valpha24-positive natural killer T cells: a prognostic factor for primary colorectal carcinomas
-
Tachibana, T., Onodera, H., Tsuruyama, T., et al. Increased intratumor Valpha24-positive natural killer T cells: a prognostic factor for primary colorectal carcinomas. Clin Cancer Res 11 (2005), 7322–7327.
-
(2005)
Clin Cancer Res
, vol.11
, pp. 7322-7327
-
-
Tachibana, T.1
Onodera, H.2
Tsuruyama, T.3
-
76
-
-
27644443729
-
NKT cell-dependent leukemia eradication following stem cell mobilization with potent G-CSF analogs
-
Morris, E.S., MacDonald, K.P., Rowe, V., et al. NKT cell-dependent leukemia eradication following stem cell mobilization with potent G-CSF analogs. J Clin Invest 115 (2005), 3093–3103.
-
(2005)
J Clin Invest
, vol.115
, pp. 3093-3103
-
-
Morris, E.S.1
MacDonald, K.P.2
Rowe, V.3
-
77
-
-
34248172955
-
Host NKT cells can prevent graft-versus-host disease and permit graft antitumor activity after bone marrow transplantation
-
Pillai, A.B., George, T.I., Dutt, S., Teo, P., Strober, S., Host NKT cells can prevent graft-versus-host disease and permit graft antitumor activity after bone marrow transplantation. J Immunol 178 (2007), 6242–6251.
-
(2007)
J Immunol
, vol.178
, pp. 6242-6251
-
-
Pillai, A.B.1
George, T.I.2
Dutt, S.3
Teo, P.4
Strober, S.5
-
78
-
-
84881493640
-
Invariant natural killer T cells reconstitution and the control of leukemia relapse in pediatric haploidentical hematopoietic stem cell transplantation
-
Casorati, G., de Lalla, C., Dellabona, P., Invariant natural killer T cells reconstitution and the control of leukemia relapse in pediatric haploidentical hematopoietic stem cell transplantation. Oncoimmunology 1 (2012), 355–357.
-
(2012)
Oncoimmunology
, vol.1
, pp. 355-357
-
-
Casorati, G.1
de Lalla, C.2
Dellabona, P.3
-
79
-
-
79955006106
-
Invariant NKT cell reconstitution in pediatric leukemia patients given HLA-haploidentical stem cell transplantation defines distinct CD4+ and CD4- subset dynamics and correlates with remission state
-
de Lalla, C., Rinaldi, A., Montagna, D., et al. Invariant NKT cell reconstitution in pediatric leukemia patients given HLA-haploidentical stem cell transplantation defines distinct CD4+ and CD4- subset dynamics and correlates with remission state. J Immunol 186 (2011), 4490–4499.
-
(2011)
J Immunol
, vol.186
, pp. 4490-4499
-
-
de Lalla, C.1
Rinaldi, A.2
Montagna, D.3
-
80
-
-
79960464272
-
On the use of donor-derived iNKT cells for adoptive immunotherapy to prevent leukemia recurrence in pediatric recipients of HLA haploidentical HSCT for hematological malignancies
-
Dellabona, P., Casorati, G., de Lalla, C., Montagna, D., Locatelli, F., On the use of donor-derived iNKT cells for adoptive immunotherapy to prevent leukemia recurrence in pediatric recipients of HLA haploidentical HSCT for hematological malignancies. Clin Immunol 140 (2011), 152–159.
-
(2011)
Clin Immunol
, vol.140
, pp. 152-159
-
-
Dellabona, P.1
Casorati, G.2
de Lalla, C.3
Montagna, D.4
Locatelli, F.5
-
81
-
-
66349083007
-
Valpha24-invariant NKT cells mediate antitumor activity via killing of tumor-associated macrophages
-
Song, L., Asgharzadeh, S., Salo, J., et al. Valpha24-invariant NKT cells mediate antitumor activity via killing of tumor-associated macrophages. J Clin Invest 119 (2009), 1524–1536.
-
(2009)
J Clin Invest
, vol.119
, pp. 1524-1536
-
-
Song, L.1
Asgharzadeh, S.2
Salo, J.3
-
82
-
-
35648995976
-
Interleukin-6 and its receptor in cancer: implications for translational therapeutics
-
Hong, D.S., Angelo, L.S., Kurzrock, R., Interleukin-6 and its receptor in cancer: implications for translational therapeutics. Cancer 110 (2007), 1911–1928.
-
(2007)
Cancer
, vol.110
, pp. 1911-1928
-
-
Hong, D.S.1
Angelo, L.S.2
Kurzrock, R.3
-
83
-
-
84868705788
-
Invariant NKT cells as novel targets for immunotherapy in solid tumors
-
Pilones, K.A., Aryankalayil, J., Demaria, S., Invariant NKT cells as novel targets for immunotherapy in solid tumors. Clin Dev Immunol, 2012, 2012, 720803.
-
(2012)
Clin Dev Immunol
, vol.2012
, pp. 720803
-
-
Pilones, K.A.1
Aryankalayil, J.2
Demaria, S.3
-
84
-
-
0032698211
-
Antitumor cytotoxicity mediated by ligand-activated human V alpha24 NKT cells
-
Kawano, T., Nakayama, T., Kamada, N., et al. Antitumor cytotoxicity mediated by ligand-activated human V alpha24 NKT cells. Cancer Res 59 (1999), 5102–5105.
-
(1999)
Cancer Res
, vol.59
, pp. 5102-5105
-
-
Kawano, T.1
Nakayama, T.2
Kamada, N.3
-
85
-
-
0035478706
-
Loss of IFN-gamma production by invariant NK T cells in advanced cancer
-
Tahir, S.M., Cheng, O., Shaulov, A., et al. Loss of IFN-gamma production by invariant NK T cells in advanced cancer. J Immunol 167 (2001), 4046–4050.
-
(2001)
J Immunol
, vol.167
, pp. 4046-4050
-
-
Tahir, S.M.1
Cheng, O.2
Shaulov, A.3
-
86
-
-
0043163751
-
Severe and selective deficiency of interferon-gamma-producing invariant natural killer T cells in patients with myelodysplastic syndromes
-
Fujii, S., Shimizu, K., Klimek, V., Geller, M.D., Nimer, S.D., Dhodapkar, M.V., Severe and selective deficiency of interferon-gamma-producing invariant natural killer T cells in patients with myelodysplastic syndromes. Br J Haematol 122 (2003), 617–622.
-
(2003)
Br J Haematol
, vol.122
, pp. 617-622
-
-
Fujii, S.1
Shimizu, K.2
Klimek, V.3
Geller, M.D.4
Nimer, S.D.5
Dhodapkar, M.V.6
-
87
-
-
0034193041
-
Analysis of human V alpha 24+ CD4+ NKT cells activated by alpha-glycosylceramide-pulsed monocyte-derived dendritic cells
-
Takahashi, T., Nieda, M., Koezuka, Y., et al. Analysis of human V alpha 24+ CD4+ NKT cells activated by alpha-glycosylceramide-pulsed monocyte-derived dendritic cells. J Immunol 164 (2000), 4458–4464.
-
(2000)
J Immunol
, vol.164
, pp. 4458-4464
-
-
Takahashi, T.1
Nieda, M.2
Koezuka, Y.3
-
88
-
-
1242351228
-
Expansion of human Valpha24+ NKT cells by repeated stimulation with KRN7000
-
Rogers, P.R., Matsumoto, A., Naidenko, O., Kronenberg, M., Mikayama, T., Kato, S., Expansion of human Valpha24+ NKT cells by repeated stimulation with KRN7000. J Immunol Methods 285 (2004), 197–214.
-
(2004)
J Immunol Methods
, vol.285
, pp. 197-214
-
-
Rogers, P.R.1
Matsumoto, A.2
Naidenko, O.3
Kronenberg, M.4
Mikayama, T.5
Kato, S.6
-
89
-
-
33750709275
-
A phase I study of in vitro expanded natural killer T cells in patients with advanced and recurrent non-small cell lung cancer
-
Motohashi, S., Ishikawa, A., Ishikawa, E., et al. A phase I study of in vitro expanded natural killer T cells in patients with advanced and recurrent non-small cell lung cancer. Clin Cancer Res 12 (2006), 6079–6086.
-
(2006)
Clin Cancer Res
, vol.12
, pp. 6079-6086
-
-
Motohashi, S.1
Ishikawa, A.2
Ishikawa, E.3
-
90
-
-
0035884974
-
Human NKT cells mediate antitumor cytotoxicity directly by recognizing target cell CD1d with bound ligand or indirectly by producing IL-2 to activate NK cells
-
Metelitsa, L.S., Naidenko, O.V., Kant, A., et al. Human NKT cells mediate antitumor cytotoxicity directly by recognizing target cell CD1d with bound ligand or indirectly by producing IL-2 to activate NK cells. J Immunol 167 (2001), 3114–3122.
-
(2001)
J Immunol
, vol.167
, pp. 3114-3122
-
-
Metelitsa, L.S.1
Naidenko, O.V.2
Kant, A.3
-
91
-
-
27744562232
-
Differential antitumor immunity mediated by NKT cell subsets in vivo
-
Crowe, N.Y., Coquet, J.M., Berzins, S.P., et al. Differential antitumor immunity mediated by NKT cell subsets in vivo. J Exp Med 202 (2005), 1279–1288.
-
(2005)
J Exp Med
, vol.202
, pp. 1279-1288
-
-
Crowe, N.Y.1
Coquet, J.M.2
Berzins, S.P.3
-
92
-
-
65249176389
-
Enrichment of human CD4+ V(alpha)24/Vbeta11 invariant NKT cells in intrahepatic malignant tumors
-
Bricard, G., Cesson, V., Devevre, E., et al. Enrichment of human CD4+ V(alpha)24/Vbeta11 invariant NKT cells in intrahepatic malignant tumors. J Immunol 182 (2009), 5140–5151.
-
(2009)
J Immunol
, vol.182
, pp. 5140-5151
-
-
Bricard, G.1
Cesson, V.2
Devevre, E.3
-
93
-
-
24144461318
-
Ex vivo expanded human CD4+ regulatory NKT cells suppress expansion of tumor antigen-specific CTLs
-
Osada, T., Morse, M.A., Lyerly, H.K., Clay, T.M., Ex vivo expanded human CD4+ regulatory NKT cells suppress expansion of tumor antigen-specific CTLs. Int Immunol 17 (2005), 1143–1155.
-
(2005)
Int Immunol
, vol.17
, pp. 1143-1155
-
-
Osada, T.1
Morse, M.A.2
Lyerly, H.K.3
Clay, T.M.4
-
94
-
-
0034569025
-
NKT cell-mediated repression of tumor immunosurveillance by IL-13 and the IL-4R-STAT6 pathway
-
Terabe, M., Matsui, S., Noben-Trauth, N., et al. NKT cell-mediated repression of tumor immunosurveillance by IL-13 and the IL-4R-STAT6 pathway. Nat Immunol 1 (2000), 515–520.
-
(2000)
Nat Immunol
, vol.1
, pp. 515-520
-
-
Terabe, M.1
Matsui, S.2
Noben-Trauth, N.3
-
95
-
-
13244279490
-
Unmasking immunosurveillance against a syngeneic colon cancer by elimination of CD4+ NKT regulatory cells and IL-13
-
Park, J.M., Terabe, M., van den Broeke, L.T., Donaldson, D.D., Berzofsky, J.A., Unmasking immunosurveillance against a syngeneic colon cancer by elimination of CD4+ NKT regulatory cells and IL-13. Int J Cancer 114 (2005), 80–87.
-
(2005)
Int J Cancer
, vol.114
, pp. 80-87
-
-
Park, J.M.1
Terabe, M.2
van den Broeke, L.T.3
Donaldson, D.D.4
Berzofsky, J.A.5
-
96
-
-
0037111416
-
Resistance to metastatic disease in STAT6-deficient mice requires hemopoietic and nonhemopoietic cells and is IFN-gamma dependent
-
Ostrand-Rosenberg, S., Clements, V.K., Terabe, M., Park, J.M., Berzofsky, J.A., Dissanayake, S.K., Resistance to metastatic disease in STAT6-deficient mice requires hemopoietic and nonhemopoietic cells and is IFN-gamma dependent. J Immunol 169 (2002), 5796–5804.
-
(2002)
J Immunol
, vol.169
, pp. 5796-5804
-
-
Ostrand-Rosenberg, S.1
Clements, V.K.2
Terabe, M.3
Park, J.M.4
Berzofsky, J.A.5
Dissanayake, S.K.6
-
97
-
-
0942276861
-
Therapeutic activation of Valpha24+Vbeta11+ NKT cells in human subjects results in highly coordinated secondary activation of acquired and innate immunity
-
Nieda, M., Okai, M., Tazbirkova, A., et al. Therapeutic activation of Valpha24+Vbeta11+ NKT cells in human subjects results in highly coordinated secondary activation of acquired and innate immunity. Blood 103 (2004), 383–389.
-
(2004)
Blood
, vol.103
, pp. 383-389
-
-
Nieda, M.1
Okai, M.2
Tazbirkova, A.3
-
98
-
-
0348013202
-
The NKT cell system: bridging innate and acquired immunity
-
Taniguchi, M., Seino, K., Nakayama, T., The NKT cell system: bridging innate and acquired immunity. Nat Immunol 4 (2003), 1164–1165.
-
(2003)
Nat Immunol
, vol.4
, pp. 1164-1165
-
-
Taniguchi, M.1
Seino, K.2
Nakayama, T.3
-
99
-
-
0032547849
-
CD1d-mediated recognition of an alpha-galactosylceramide by natural killer T cells is highly conserved through mammalian evolution
-
Brossay, L., Chioda, M., Burdin, N., et al. CD1d-mediated recognition of an alpha-galactosylceramide by natural killer T cells is highly conserved through mammalian evolution. J Exp Med 188 (1998), 1521–1528.
-
(1998)
J Exp Med
, vol.188
, pp. 1521-1528
-
-
Brossay, L.1
Chioda, M.2
Burdin, N.3
-
100
-
-
84908612560
-
Invariant NKT cells with chimeric antigen receptor provide a novel platform for safe and effective cancer immunotherapy
-
Heczey, A., Liu, D., Tian, G., et al. Invariant NKT cells with chimeric antigen receptor provide a novel platform for safe and effective cancer immunotherapy. Blood 124 (2014), 2824–2833.
-
(2014)
Blood
, vol.124
, pp. 2824-2833
-
-
Heczey, A.1
Liu, D.2
Tian, G.3
-
101
-
-
84867052186
-
Clinical significance of tumor-associated inflammatory cells in metastatic neuroblastoma
-
Asgharzadeh, S., Salo, J.A., Ji, L., et al. Clinical significance of tumor-associated inflammatory cells in metastatic neuroblastoma. J Clin Oncol 30 (2012), 3525–3532.
-
(2012)
J Clin Oncol
, vol.30
, pp. 3525-3532
-
-
Asgharzadeh, S.1
Salo, J.A.2
Ji, L.3
-
102
-
-
84974633307
-
CD62L+ NKT cells have prolonged persistence and antitumor activity in vivo
-
Tian, G., Courtney, A.N., Jena, B., et al. CD62L+ NKT cells have prolonged persistence and antitumor activity in vivo. J Clin Invest 126 (2016), 2341–2355.
-
(2016)
J Clin Invest
, vol.126
, pp. 2341-2355
-
-
Tian, G.1
Courtney, A.N.2
Jena, B.3
-
103
-
-
84904394259
-
Serial transfer of single-cell-derived immunocompetence reveals stemness of CD8(+) central memory T cells
-
Graef, P., Buchholz, V.R., Stemberger, C., et al. Serial transfer of single-cell-derived immunocompetence reveals stemness of CD8(+) central memory T cells. Immunity 41 (2014), 116–126.
-
(2014)
Immunity
, vol.41
, pp. 116-126
-
-
Graef, P.1
Buchholz, V.R.2
Stemberger, C.3
-
104
-
-
84868221578
-
Phenotypic and functional attributes of lentivirus-modified CD19-specific human CD8+ central memory T cells manufactured at clinical scale
-
Wang, X., Naranjo, A., Brown, C.E., et al. Phenotypic and functional attributes of lentivirus-modified CD19-specific human CD8+ central memory T cells manufactured at clinical scale. J Immunother 35 (2012), 689–701.
-
(2012)
J Immunother
, vol.35
, pp. 689-701
-
-
Wang, X.1
Naranjo, A.2
Brown, C.E.3
-
105
-
-
84959328185
-
Chimeric antigen receptor-modified T cells derived from defined CD8+ and CD4+ subsets confer superior antitumor reactivity in vivo
-
Sommermeyer, D., Hudecek, M., Kosasih, P.L., et al. Chimeric antigen receptor-modified T cells derived from defined CD8+ and CD4+ subsets confer superior antitumor reactivity in vivo. Leukemia 30 (2016), 492–500.
-
(2016)
Leukemia
, vol.30
, pp. 492-500
-
-
Sommermeyer, D.1
Hudecek, M.2
Kosasih, P.L.3
-
106
-
-
0019462963
-
Hybrid antibodies with dual specificity for the delivery of ricin to immunoglobulin-bearing target cells
-
Raso, V., Griffin, T., Hybrid antibodies with dual specificity for the delivery of ricin to immunoglobulin-bearing target cells. Cancer Res 41 (1981), 2073–2078.
-
(1981)
Cancer Res
, vol.41
, pp. 2073-2078
-
-
Raso, V.1
Griffin, T.2
-
108
-
-
0343415665
-
A recombinant bispecific single-chain antibody, CD19 x CD3, induces rapid and high lymphoma-directed cytotoxicity by unstimulated T lymphocytes
-
Loffler, A., Kufer, P., Lutterbuse, R., et al. A recombinant bispecific single-chain antibody, CD19 x CD3, induces rapid and high lymphoma-directed cytotoxicity by unstimulated T lymphocytes. Blood 95 (2000), 2098–2103.
-
(2000)
Blood
, vol.95
, pp. 2098-2103
-
-
Loffler, A.1
Kufer, P.2
Lutterbuse, R.3
-
109
-
-
33645007038
-
T-cell activation and B-cell depletion in chimpanzees treated with a bispecific anti-CD19/anti-CD3 single-chain antibody construct
-
Schlereth, B., Quadt, C., Dreier, T., et al. T-cell activation and B-cell depletion in chimpanzees treated with a bispecific anti-CD19/anti-CD3 single-chain antibody construct. Cancer Immunol Immunother 55 (2006), 503–514.
-
(2006)
Cancer Immunol Immunother
, vol.55
, pp. 503-514
-
-
Schlereth, B.1
Quadt, C.2
Dreier, T.3
-
110
-
-
84926099033
-
Safety and activity of blinatumomab for adult patients with relapsed or refractory B-precursor acute lymphoblastic leukaemia: a multicentre, single-arm, phase 2 study
-
Topp, M.S., Gokbuget, N., Stein, A.S., et al. Safety and activity of blinatumomab for adult patients with relapsed or refractory B-precursor acute lymphoblastic leukaemia: a multicentre, single-arm, phase 2 study. Lancet Oncol 16 (2015), 57–66.
-
(2015)
Lancet Oncol
, vol.16
, pp. 57-66
-
-
Topp, M.S.1
Gokbuget, N.2
Stein, A.S.3
-
111
-
-
84916639631
-
Phase II trial of the anti-CD19 bispecific T cell-engager blinatumomab shows hematologic and molecular remissions in patients with relapsed or refractory B-precursor acute lymphoblastic leukemia
-
Topp, M.S., Gokbuget, N., Zugmaier, G., et al. Phase II trial of the anti-CD19 bispecific T cell-engager blinatumomab shows hematologic and molecular remissions in patients with relapsed or refractory B-precursor acute lymphoblastic leukemia. J Clin Oncol 32 (2014), 4134–4140.
-
(2014)
J Clin Oncol
, vol.32
, pp. 4134-4140
-
-
Topp, M.S.1
Gokbuget, N.2
Zugmaier, G.3
-
112
-
-
84944472777
-
Are BiTEs the “missing link” in cancer therapy?
-
Suryadevara, C.M., Gedeon, P.C., Sanchez-Perez, L., et al. Are BiTEs the “missing link” in cancer therapy?. Oncoimmunology, 4, 2015, e1008339.
-
(2015)
Oncoimmunology
, vol.4
, pp. e1008339
-
-
Suryadevara, C.M.1
Gedeon, P.C.2
Sanchez-Perez, L.3
-
113
-
-
84878921225
-
A sensitivity scale for targeting T cells with chimeric antigen receptors (CARs) and bispecific T-cell Engagers (BiTEs)
-
Stone, J.D., Aggen, D.H., Schietinger, A., Schreiber, H., Kranz, D.M., A sensitivity scale for targeting T cells with chimeric antigen receptors (CARs) and bispecific T-cell Engagers (BiTEs). Oncoimmunology 1 (2012), 863–873.
-
(2012)
Oncoimmunology
, vol.1
, pp. 863-873
-
-
Stone, J.D.1
Aggen, D.H.2
Schietinger, A.3
Schreiber, H.4
Kranz, D.M.5
-
114
-
-
84871389574
-
Bispecific and trispecific killer cell engagers directly activate human NK cells through CD16 signaling and induce cytotoxicity and cytokine production
-
Gleason, M.K., Verneris, M.R., Todhunter, D.A., et al. Bispecific and trispecific killer cell engagers directly activate human NK cells through CD16 signaling and induce cytotoxicity and cytokine production. Mol Cancer Ther 11 (2012), 2674–2684.
-
(2012)
Mol Cancer Ther
, vol.11
, pp. 2674-2684
-
-
Gleason, M.K.1
Verneris, M.R.2
Todhunter, D.A.3
-
115
-
-
84978396441
-
IL15 trispecific killer engagers (TriKE) make natural killer cells specific to CD33+ targets while also inducing persistence, in vivo expansion, and enhanced function
-
Vallera, D.A., Felices, M., McElmurry, R., et al. IL15 trispecific killer engagers (TriKE) make natural killer cells specific to CD33+ targets while also inducing persistence, in vivo expansion, and enhanced function. Clin Cancer Res 22 (2016), 3440–3450.
-
(2016)
Clin Cancer Res
, vol.22
, pp. 3440-3450
-
-
Vallera, D.A.1
Felices, M.2
McElmurry, R.3
-
116
-
-
0037108839
-
Visualization of effective tumor targeting by CD8+ natural killer T cells redirected with bispecific antibody F(ab')(2)HER2xCD3
-
Scheffold, C., Kornacker, M., Scheffold, Y.C., Contag, C.H., Negrin, R.S., Visualization of effective tumor targeting by CD8+ natural killer T cells redirected with bispecific antibody F(ab')(2)HER2xCD3. Cancer Res 62 (2002), 5785–5791.
-
(2002)
Cancer Res
, vol.62
, pp. 5785-5791
-
-
Scheffold, C.1
Kornacker, M.2
Scheffold, Y.C.3
Contag, C.H.4
Negrin, R.S.5
-
117
-
-
84936934796
-
TRUCKs: the fourth generation of CARs
-
Chmielewski, M., Abken, H., TRUCKs: the fourth generation of CARs. Expert Opin Biol Ther 15 (2015), 1145–1154.
-
(2015)
Expert Opin Biol Ther
, vol.15
, pp. 1145-1154
-
-
Chmielewski, M.1
Abken, H.2
-
118
-
-
80052257433
-
IL-12 release by engineered T cells expressing chimeric antigen receptors can effectively Muster an antigen-independent macrophage response on tumor cells that have shut down tumor antigen expression
-
Chmielewski, M., Kopecky, C., Hombach, A.A., Abken, H., IL-12 release by engineered T cells expressing chimeric antigen receptors can effectively Muster an antigen-independent macrophage response on tumor cells that have shut down tumor antigen expression. Cancer Res 71 (2011), 5697–5706.
-
(2011)
Cancer Res
, vol.71
, pp. 5697-5706
-
-
Chmielewski, M.1
Kopecky, C.2
Hombach, A.A.3
Abken, H.4
-
119
-
-
84890214448
-
CAR T cells: driving the road from the laboratory to the clinic
-
Cheadle, E.J., Gornall, H., Baldan, V., Hanson, V., Hawkins, R.E., Gilham, D.E., CAR T cells: driving the road from the laboratory to the clinic. Immunol Rev 257 (2014), 91–106.
-
(2014)
Immunol Rev
, vol.257
, pp. 91-106
-
-
Cheadle, E.J.1
Gornall, H.2
Baldan, V.3
Hanson, V.4
Hawkins, R.E.5
Gilham, D.E.6
-
120
-
-
84858759305
-
Tumor-targeted T cells modified to secrete IL-12 eradicate systemic tumors without need for prior conditioning
-
Pegram, H.J., Lee, J.C., Hayman, E.G., et al. Tumor-targeted T cells modified to secrete IL-12 eradicate systemic tumors without need for prior conditioning. Blood 119 (2012), 4133–4141.
-
(2012)
Blood
, vol.119
, pp. 4133-4141
-
-
Pegram, H.J.1
Lee, J.C.2
Hayman, E.G.3
|