-
1
-
-
84860383419
-
The biology and therapeutic targeting of the proprotein convertases
-
Seidah, N. G., and Prat, A. (2012) The biology and therapeutic targeting of the proprotein convertases. Nat. Rev. Drug Discov. 11, 367–383
-
(2012)
Nat. Rev. Drug Discov.
, vol.11
, pp. 367-383
-
-
Seidah, N.G.1
Prat, A.2
-
2
-
-
84881238159
-
The multifaceted proprotein convertases: Their unique, redundant, complementary, and opposite functions
-
Seidah, N. G., Sadr, M. S., Chrétien, M., and Mbikay, M. (2013) The multifaceted proprotein convertases: their unique, redundant, complementary, and opposite functions. J. Biol. Chem. 288, 21473–21481
-
(2013)
J. Biol. Chem.
, vol.288
, pp. 21473-21481
-
-
Seidah, N.G.1
Sadr, M.S.2
Chrétien, M.3
Mbikay, M.4
-
3
-
-
43049141452
-
The activation and physiological functions of the proprotein convertases
-
Seidah, N. G., Mayer, G., Zaid, A., Rousselet, E., Nassoury, N., Poirier, S., Essalmani, R., and Prat, A. (2008) The activation and physiological functions of the proprotein convertases. Int. J. Biochem. Cell Biol. 40, 1111–1125
-
(2008)
Int. J. Biochem. Cell Biol.
, vol.40
, pp. 1111-1125
-
-
Seidah, N.G.1
Mayer, G.2
Zaid, A.3
Rousselet, E.4
Nassoury, N.5
Poirier, S.6
Essalmani, R.7
Prat, A.8
-
4
-
-
0032443652
-
Failure of ventral closure and axial rotation in embryos lacking the proprotein convertase furin
-
Roebroek, A. J., Umans, L., Pauli, I. G., Robertson, E. J., van Leuven, F., Van de Ven, W. J., and Constam, D. B. (1998) Failure of ventral closure and axial rotation in embryos lacking the proprotein convertase furin. Development 125, 4863– 4876
-
(1998)
Development
, vol.125
, pp. 4863-4876
-
-
Roebroek, A.J.1
Umans, L.2
Pauli, I.G.3
Robertson, E.J.4
Van Leuven, F.5
Van De Ven, W.J.6
Constam, D.B.7
-
5
-
-
44449128120
-
In vivo functions of the proprotein convertase PC5/6 during mouse development: Gdf11 is a likely substrate
-
Essalmani, R., Zaid, A., Marcinkiewicz, J., Chamberland, A., Pasquato, A., Seidah, N. G., and Prat, A. (2008) In vivo functions of the proprotein convertase PC5/6 during mouse development: Gdf11 is a likely substrate. Proc. Natl. Acad. Sci. U.S.A. 105, 5750 –5755
-
(2008)
Proc. Natl. Acad. Sci. U.S.A.
, vol.105
, pp. 5750-5755
-
-
Essalmani, R.1
Zaid, A.2
Marcinkiewicz, J.3
Chamberland, A.4
Pasquato, A.5
Seidah, N.G.6
Prat, A.7
-
6
-
-
44849135766
-
VACTERL/caudal regression/Currarino syndrome-like malformations in mice with mutation in the proprotein convertase Pcsk5
-
Szumska, D., Pieles, G., Essalmani, R., Bilski, M., Mesnard, D., Kaur, K., Franklyn, A., El Omari, K., Jefferis, J., Bentham, J., Taylor, J. M., Schneider, J. E., Arnold, S. J., Johnson, P., Tymowska-Lalanne, Z., et al. (2008) VACTERL/caudal regression/Currarino syndrome-like malformations in mice with mutation in the proprotein convertase Pcsk5. Genes Dev. 22, 1465–1477
-
(2008)
Genes Dev.
, vol.22
, pp. 1465-1477
-
-
Szumska, D.1
Pieles, G.2
Essalmani, R.3
Bilski, M.4
Mesnard, D.5
Kaur, K.6
Franklyn, A.7
El Omari, K.8
Jefferis, J.9
Bentham, J.10
Taylor, J.M.11
Schneider, J.E.12
Arnold, S.J.13
Johnson, P.14
Tymowska-Lalanne, Z.15
-
7
-
-
0034194471
-
SPC4/PACE4 regulates a TGF signaling network during axis formation
-
Constam, D. B., and Robertson, E. J. (2000) SPC4/PACE4 regulates a TGF signaling network during axis formation. Genes Dev. 14, 1146–1155
-
(2000)
Genes Dev.
, vol.14
, pp. 1146-1155
-
-
Constam, D.B.1
Robertson, E.J.2
-
8
-
-
84886441051
-
Disruption of the expression of the proprotein convertase pc7 reduces bdnf production and affects learning and memory in mice
-
Wetsel, W. C., Rodriguiz, R. M., Guillemot, J., Rousselet, E., Essalmani, R., Kim, I. H., Bryant, J. C., Marcinkiewicz, J., Desjardins, R., Day, R., Constam, D. B., Prat, A., and Seidah, N. G. (2013) Disruption of the expression of the proprotein convertase PC7 reduces BDNF production and affects learning and memory in mice. Proc. Natl. Acad. Sci. U.S.A. 110, 17362–17367
-
(2013)
Proc. Natl. Acad. Sci. U.S.A.
, vol.110
, pp. 17362-17367
-
-
Wetsel, W.C.1
Rodriguiz, R.M.2
Guillemot, J.3
Rousselet, E.4
Essalmani, R.5
Kim, I.H.6
Bryant, J.C.7
Marcinkiewicz, J.8
Desjardins, R.9
Day, R.10
Constam, D.B.11
Prat, A.12
Seidah, N.G.13
-
9
-
-
0023096623
-
The regulation of natural anticoagulant pathways
-
Esmon, C. T. (1987) The regulation of natural anticoagulant pathways. Science 235, 1348 –1352
-
(1987)
Science
, vol.235
, pp. 1348-1352
-
-
Esmon, C.T.1
-
10
-
-
0018415278
-
Characterization of protein s, a -carboxyglutamic acid containing protein from bovine and human plasma
-
DiScipio, R. G., and Davie, E. W. (1979) Characterization of protein S, a -carboxyglutamic acid containing protein from bovine and human plasma. Biochemistry 18, 899 –904
-
(1979)
Biochemistry
, vol.18
, pp. 899-904
-
-
DiScipio, R.G.1
Davie, E.W.2
-
11
-
-
0020491227
-
Amino acid sequence of the light chain of bovine protein C
-
Fernlund, P., and Stenflo, J. (1982) Amino acid sequence of the light chain of bovine protein C. J. Biol. Chem. 257, 12170 –12179
-
(1982)
J. Biol. Chem.
, vol.257
, pp. 12170-12179
-
-
Fernlund, P.1
Stenflo, J.2
-
12
-
-
0020515543
-
The occurrence of -hydroxyaspartic acid in the Vitamin K-dependent blood coagulation zymogens
-
McMullen, B. A., Fujikawa, K., and Kisiel, W. (1983) The occurrence of -hydroxyaspartic acid in the vitamin K-dependent blood coagulation zymogens. Biochem. Biophys. Res. Commun. 115, 8 –14
-
(1983)
Biochem. Biophys. Res. Commun.
, vol.115
, pp. 8-14
-
-
McMullen, B.A.1
Fujikawa, K.2
Kisiel, W.3
-
13
-
-
0023500177
-
Pro-peptide of human protein c is necessary for -carboxylation
-
Foster, D. C., Rudinski, M. S., Schach, B. G., Berkner, K. L., Kumar, A. A., Hagen, F. S., Sprecher, C. A., Insley, M. Y., and Davie, E. W. (1987) Pro-peptide of human protein C is necessary for -carboxylation. Biochemistry 26, 7003–7011
-
(1987)
Biochemistry
, vol.26
, pp. 7003-7011
-
-
Foster, D.C.1
Rudinski, M.S.2
Schach, B.G.3
Berkner, K.L.4
Kumar, A.A.5
Hagen, F.S.6
Sprecher, C.A.7
Insley, M.Y.8
Davie, E.W.9
-
14
-
-
80055095617
-
The endothelial cell protein c receptor: Its role in thrombosis
-
Navarro, S., Bonet, E., Estellés, A., Montes, R., Hermida, J., Martos, L., España, F., and Medina, P. (2011) The endothelial cell protein C receptor: its role in thrombosis. Thromb. Res. 128, 410 – 416
-
(2011)
Thromb. Res.
, vol.128
, pp. 410-416
-
-
Navarro, S.1
Bonet, E.2
Estellés, A.3
Montes, R.4
Hermida, J.5
Martos, L.6
España, F.7
Medina, P.8
-
15
-
-
34250711947
-
Activated protein C
-
Griffin, J. H., Fernández, J. A., Gale, A. J., and Mosnier, L. O. (2007) Activated protein C. J. Thromb. Haemost. 5, 73– 80
-
(2007)
J. Thromb. Haemost.
, vol.5
, pp. 73-80
-
-
Griffin, J.H.1
Fernández, J.A.2
Gale, A.J.3
Mosnier, L.O.4
-
16
-
-
51449117497
-
Activated protein C: An anticoagulant that does more than stop clots
-
Jackson, C. J., and Xue, M. (2008) Activated protein C: an anticoagulant that does more than stop clots. Int. J. Biochem. Cell Biol. 40, 2692–2697
-
(2008)
Int. J. Biochem. Cell Biol.
, vol.40
, pp. 2692-2697
-
-
Jackson, C.J.1
Xue, M.2
-
17
-
-
0037036069
-
Activation of endothelial cell protease activated receptor 1 by the protein c pathway
-
Riewald, M., Petrovan, R. J., Donner, A., Mueller, B. M., and Ruf, W. (2002) Activation of endothelial cell protease activated receptor 1 by the protein C pathway. Science 296, 1880 –1882
-
(2002)
Science
, vol.296
, pp. 1880-1882
-
-
Riewald, M.1
Petrovan, R.J.2
Donner, A.3
Mueller, B.M.4
Ruf, W.5
-
18
-
-
84944629624
-
Neuroinflam-mation-induced interactions between protease-activated receptor 1 and proprotein convertases in HIV-associated neurocognitive disorder
-
Kim, W., Zekas, E., Lodge, R., Susan-Resiga, D., Marcinkiewicz, E., Essalmani, R., Mihara, K., Ramachandran, R., Asahchop, E., Gelman, B., Cohen, É. A., Power, C., Hollenberg, M. D., and Seidah, N. G. (2015) Neuroinflam-mation-induced interactions between protease-activated receptor 1 and proprotein convertases in HIV-associated neurocognitive disorder. Mol. Cell Biol. 35, 3684 –3700
-
(2015)
Mol. Cell Biol.
, vol.35
, pp. 3684-3700
-
-
Kim, W.1
Zekas, E.2
Lodge, R.3
Susan-Resiga, D.4
Marcinkiewicz, E.5
Essalmani, R.6
Mihara, K.7
Ramachandran, R.8
Asahchop, E.9
Gelman, B.10
Cohen, É.A.11
Power, C.12
Hollenberg, M.D.13
Seidah, N.G.14
-
19
-
-
0028006634
-
Identification of a region in protein c involved in thrombomodulin-stimulated activation by thrombin: Potential repulsion at anion-binding site i in thrombin
-
Grinnell, B. W., Gerlitz, B., and Berg, D. T. (1994) Identification of a region in protein C involved in thrombomodulin-stimulated activation by thrombin: potential repulsion at anion-binding site I in thrombin. Biochem. J. 303, 929 –933
-
(1994)
Biochem. J
, vol.303
, pp. 929-933
-
-
Grinnell, B.W.1
Gerlitz, B.2
Berg, D.T.3
-
20
-
-
0025056635
-
Endoproteolytic processing of the dibasic cleavage site in the human protein c precursor in transfected mammalian cells: Effects of sequence alterations on efficiency of cleavage
-
Foster, D. C., Sprecher, C. A., Holly, R. D., Gambee, J. E., Walker, K. M., and Kumar, A. A. (1990) Endoproteolytic processing of the dibasic cleavage site in the human protein C precursor in transfected mammalian cells: effects of sequence alterations on efficiency of cleavage. Biochemistry 29, 347–354
-
(1990)
Biochemistry
, vol.29
, pp. 347-354
-
-
Foster, D.C.1
Sprecher, C.A.2
Holly, R.D.3
Gambee, J.E.4
Walker, K.M.5
Kumar, A.A.6
-
21
-
-
0026093223
-
Endoproteolytic processing of the human protein c precursor by the yeast kex2 endopeptidase coexpressed in mammalian cells
-
Foster, D. C., Holly, R. D., Sprecher, C. A., Walker, K. M., and Kumar, A. A. (1991) Endoproteolytic processing of the human protein C precursor by the yeast Kex2 endopeptidase coexpressed in mammalian cells. Biochemistry 30, 367–372
-
(1991)
Biochemistry
, vol.30
, pp. 367-372
-
-
Foster, D.C.1
Holly, R.D.2
Sprecher, C.A.3
Walker, K.M.4
Kumar, A.A.5
-
22
-
-
0028817985
-
Proteolytic maturation of protein c upon engineering the mouse mammary gland to express furin
-
Drews, R., Paleyanda, R. K., Lee, T. K., Chang, R. R., Rehemtulla, A., Kaufman, R. J., Drohan, W. N., and Lubon´, H. (1995) Proteolytic maturation of protein C upon engineering the mouse mammary gland to express furin. Proc. Natl. Acad. Sci. U.S.A. 92, 10462–10466
-
(1995)
Proc. Natl. Acad. Sci. U.S.A.
, vol.92
, pp. 10462-10466
-
-
Drews, R.1
Paleyanda, R.K.2
Lee, T.K.3
Chang, R.R.4
Rehemtulla, A.5
Kaufman, R.J.6
Drohan, W.N.7
Lubon, H.8
-
23
-
-
79953022875
-
In vivo evidence that furin from hepatocytes inactivates PCSK9
-
Essalmani, R., Susan-Resiga, D., Chamberland, A., Abifadel, M., Creemers, J. W., Boileau, C., Seidah, N. G., and Prat, A. (2011) In vivo evidence that furin from hepatocytes inactivates PCSK9. J. Biol. Chem. 286, 4257– 4263
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 4257-4263
-
-
Essalmani, R.1
Susan-Resiga, D.2
Chamberland, A.3
Abifadel, M.4
Creemers, J.W.5
Boileau, C.6
Seidah, N.G.7
Prat, A.8
-
24
-
-
84884197551
-
Furin is the primary in vivo convertase of angiopoi-etin-like 3 and endothelial lipase in hepatocytes
-
Essalmani, R., Susan-Resiga, D., Chamberland, A., Asselin, M.-C., Canuel, M., Constam, D., Creemers, J. W., Day, R., Gauthier, D., Prat, A., and Seidah, N. G. (2013) Furin is the primary in vivo convertase of angiopoi-etin-like 3 and endothelial lipase in hepatocytes. J. Biol. Chem. 288, 26410 –26418
-
(2013)
J. Biol. Chem.
, vol.288
, pp. 26410-26418
-
-
Essalmani, R.1
Susan-Resiga, D.2
Chamberland, A.3
Asselin, M.-C.4
Canuel, M.5
Constam, D.6
Creemers, J.W.7
Day, R.8
Gauthier, D.9
Prat, A.10
Seidah, N.G.11
-
25
-
-
0034700141
-
The design, synthesis, and evaluation of molecules that enable or enhance cellular uptake: Peptoid molecular transporters
-
Wender, P. A., Mitchell, D. J., Pattabiraman, K., Pelkey, E. T., Steinman, L., and Rothbard, J. B. (2000) The design, synthesis, and evaluation of molecules that enable or enhance cellular uptake: peptoid molecular transporters. Proc. Natl. Acad. Sci. U.S.A. 97, 13003–13008
-
(2000)
Proc. Natl. Acad. Sci. U.S.A.
, vol.97
, pp. 13003-13008
-
-
Wender, P.A.1
Mitchell, D.J.2
Pattabiraman, K.3
Pelkey, E.T.4
Steinman, L.5
Rothbard, J.B.6
-
26
-
-
4344695207
-
Cross-inhibition between furin and lethal factor inhibitors
-
Peinado, J. R., Kacprzak, M. M., Leppla, S. H., and Lindberg, I. (2004) Cross-inhibition between furin and lethal factor inhibitors. Biochem. Biophys. Res. Commun. 321, 601– 605
-
(2004)
Biochem. Biophys. Res. Commun.
, vol.321
, pp. 601-605
-
-
Peinado, J.R.1
Kacprzak, M.M.2
Leppla, S.H.3
Lindberg, I.4
-
27
-
-
79959547680
-
Furin is the major processing enzyme of the cardiac-specific growth factor bone morphogenetic protein 10
-
Susan-Resiga, D., Essalmani, R., Hamelin, J., Asselin, M. C., Benjannet, S., Chamberland, A., Day, R., Szumska, D., Constam, D., Bhattacharya, S., Prat, A., and Seidah, N. G. (2011) Furin is the major processing enzyme of the cardiac-specific growth factor bone morphogenetic protein 10. J. Biol. Chem. 286, 22785–22794
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 22785-22794
-
-
Susan-Resiga, D.1
Essalmani, R.2
Hamelin, J.3
Asselin, M.C.4
Benjannet, S.5
Chamberland, A.6
Day, R.7
Szumska, D.8
Constam, D.9
Bhattacharya, S.10
Prat, A.11
Seidah, N.G.12
-
28
-
-
84879082514
-
Implication of the proprotein convertases in iron homeostasis: Proprotein convertase 7 sheds human transferrin receptor 1 and furin activates hep-cidin
-
Guillemot, J., Canuel, M., Essalmani, R., Prat, A., and Seidah, N. G. (2013) Implication of the proprotein convertases in iron homeostasis: proprotein convertase 7 sheds human transferrin receptor 1 and furin activates hep-cidin. Hepatology 57, 2514 –2524
-
(2013)
Hepatology
, vol.57
, pp. 2514-2524
-
-
Guillemot, J.1
Canuel, M.2
Essalmani, R.3
Prat, A.4
Seidah, N.G.5
-
29
-
-
0027429771
-
Inhibition of HIV-1 gp160-dependent membrane fusion by a furin-directed 1-antitrypsin variant
-
Anderson, E. D., Thomas, L., Hayflick, J. S., and Thomas, G. (1993) Inhibition of HIV-1 gp160-dependent membrane fusion by a furin-directed 1-antitrypsin variant. J. Biol. Chem. 268, 24887–24891
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 24887-24891
-
-
Anderson, E.D.1
Thomas, L.2
Hayflick, J.S.3
Thomas, G.4
-
30
-
-
0018672331
-
Human plasma protein c: Isolation, characterization, and mechanism of activation by -thrombin
-
Kisiel, W. (1979) Human plasma protein C: isolation, characterization, and mechanism of activation by -thrombin. J. Clin. Invest. 64, 761–769
-
(1979)
J. Clin. Invest.
, vol.64
, pp. 761-769
-
-
Kisiel, W.1
-
31
-
-
0035742909
-
Protein c activators from snake venoms and their diagnostic use
-
Gempeler-Messina, P. M., Volz, K., Bühler, B., and Müller, C. (2001) protein C activators from snake venoms and their diagnostic use. Haemostasis 31, 266 –272
-
(2001)
Haemostasis
, vol.31
, pp. 266-272
-
-
Gempeler-Messina, P.M.1
Volz, K.2
Bühler, B.3
Müller, C.4
-
32
-
-
84865210286
-
Protease-activated receptor-1 cleaved at R46 mediates cytoprotective effects
-
Schuepbach, R. A., Madon, J., Ender, M., Galli, P., and Riewald, M. (2012) Protease-activated receptor-1 cleaved at R46 mediates cytoprotective effects. J. Thromb. Haemost. 10, 1675–1684
-
(2012)
J. Thromb. Haemost.
, vol.10
, pp. 1675-1684
-
-
Schuepbach, R.A.1
Madon, J.2
Ender, M.3
Galli, P.4
Riewald, M.5
-
33
-
-
38349112617
-
The regulated cell surface zymogen activation of the proprotein convertase pc5a directs the processing of its secretory substrates
-
Mayer, G., Hamelin, J., Asselin, M. C., Pasquato, A., Marcinkiewicz, E., Tang, M., Tabibzadeh, S., and Seidah, N. G. (2008) The regulated cell surface zymogen activation of the proprotein convertase PC5A directs the processing of its secretory substrates. J. Biol. Chem. 283, 2373–2384
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 2373-2384
-
-
Mayer, G.1
Hamelin, J.2
Asselin, M.C.3
Pasquato, A.4
Marcinkiewicz, E.5
Tang, M.6
Tabibzadeh, S.7
Seidah, N.G.8
-
34
-
-
84934977276
-
Multi-leu pace4 inhibitor retention within cells is pace4 dependent and a prerequisite for antipro-liferative activity
-
Couture, F., Ly, K., Levesque, C., Kwiatkowska, A., Ait-Mohand, S., Desjardins, R., Guérin, B., and Day, R. (2015) Multi-Leu PACE4 inhibitor retention within cells is PACE4 dependent and a prerequisite for antipro-liferative activity. Biomed. Res. Int. 2015, 824014
-
(2015)
Biomed. Res. Int.
, vol.2015
, pp. 824014
-
-
Couture, F.1
Ly, K.2
Levesque, C.3
Kwiatkowska, A.4
Ait-Mohand, S.5
Desjardins, R.6
Guérin, B.7
Day, R.8
-
35
-
-
0033953050
-
Large-scale predictions of secretory proteins from mammalian genomic and est sequences
-
Ladunga, I. (2000) Large-scale predictions of secretory proteins from mammalian genomic and EST sequences. Curr. Opin. Biotechnol. 11, 13–18
-
(2000)
Curr. Opin. Biotechnol.
, vol.11
, pp. 13-18
-
-
Ladunga, I.1
-
36
-
-
85006070265
-
Posttranslational processing of secretory proteins
-
Murphy, D., and Gainer, H., eds, Wiley-Blackwell, New York
-
Seidah NG and Guillemot, J. (2016) Posttranslational Processing of Secretory Proteins. In Molecular Neuroendocrinology: From Genome to Physiology (Murphy, D., and Gainer, H., eds) pp. 171–193, Wiley-Blackwell, New York
-
(2016)
Molecular Neuroendocrinology: From Genome to Physiology
, pp. 171-193
-
-
Seidah, N.G.1
Guillemot, J.2
-
37
-
-
0028851870
-
Protein c Osaka 10 with aberrant propeptide processing: Loss of anticoagulant activity due to an amino acid substitution in the protein c precursor
-
Miyata, T., Zheng, Y. Z., Sakata, T., and Kato, H. (1995) Protein C Osaka 10 with aberrant propeptide processing: loss of anticoagulant activity due to an amino acid substitution in the protein C precursor. Thromb. Haemost. 74, 1003–1008
-
(1995)
Thromb. Haemost
, vol.74
, pp. 1003-1008
-
-
Miyata, T.1
Zheng, Y.Z.2
Sakata, T.3
Kato, H.4
-
38
-
-
0027269964
-
Five novel mutations located in exons III and ix of the protein c gene in patients presenting with defective protein c anticoagulant activity
-
Gandrille, S., Alhenc-Gelas, M., Gaussem, P., Aillaud, M. F., Dupuy, E., Juhan-Vague, I., and Aiach, M. (1993) Five novel mutations located in exons III and IX of the protein C gene in patients presenting with defective protein C anticoagulant activity. Blood 82, 159 –168
-
(1993)
Blood
, vol.82
, pp. 159-168
-
-
Gandrille, S.1
Alhenc-Gelas, M.2
Gaussem, P.3
Aillaud, M.F.4
Dupuy, E.5
Juhan-Vague, I.6
Aiach, M.7
-
39
-
-
33749378618
-
Multifunctional specificity of the protein C/activated protein c gla domain
-
Preston, R. J., Ajzner, E., Razzari, C., Karageorgi, S., Dua, S., Dahlbäck, B., and Lane, D. A. (2006) Multifunctional specificity of the protein C/activated protein C Gla domain. J. Biol. Chem. 281, 28850 –28857
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 28850-28857
-
-
Preston, R.J.1
Ajzner, E.2
Razzari, C.3
Karageorgi, S.4
Dua, S.5
Dahlbäck, B.6
Lane, D.A.7
-
40
-
-
0027474401
-
Positional and additive effects of basic amino acids on processing of precursor proteins within the constitutive secretory pathway
-
Watanabe, T., Murakami, K., and Nakayama, K. (1993) Positional and additive effects of basic amino acids on processing of precursor proteins within the constitutive secretory pathway. FEBS Lett. 320, 215–218
-
(1993)
FEBS Lett.
, vol.320
, pp. 215-218
-
-
Watanabe, T.1
Murakami, K.2
Nakayama, K.3
-
41
-
-
0036791359
-
Furin at the cutting edge: From protein traffic to em-bryogenesis and disease
-
Thomas, G. (2002) Furin at the cutting edge: from protein traffic to em-bryogenesis and disease. Nat. Rev. Mol. Cell Biol. 3, 753–766
-
(2002)
Nat. Rev. Mol. Cell Biol
, vol.3
, pp. 753-766
-
-
Thomas, G.1
-
42
-
-
19944414287
-
Limited redundancy of the proprotein convertase furin in mouse liver
-
Roebroek, A. J., Taylor, N. A., Louagie, E., Pauli, I., Smeijers, L., Snellinx, A., Lauwers, A., Van de Ven, W. J., Hartmann, D., and Creemers, J. W. (2004) Limited redundancy of the proprotein convertase furin in mouse liver. J. Biol. Chem. 279, 53442–53450
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 53442-53450
-
-
Roebroek, A.J.1
Taylor, N.A.2
Louagie, E.3
Pauli, I.4
Smeijers, L.5
Snellinx, A.6
Lauwers, A.7
Van De Ven, W.J.8
Hartmann, D.9
Creemers, J.W.10
-
43
-
-
80755153564
-
Inactivation of endothelial proprotein convertase 5/6 decreases collagen deposition in the cardiovascular system: role of fibroblast autophagy
-
Marchesi, C., Essalmani, R., Lemarié, C. A., Leibovitz, E., Ebrahimian, T., Paradis, P., Seidah, N. G., Schiffrin, E. L., and Prat, A. (2011) Inactivation of endothelial proprotein convertase 5/6 decreases collagen deposition in the cardiovascular system: role of fibroblast autophagy. J. Mol. Med. 89, 1103–1111
-
(2011)
J. Mol. Med.
, vol.89
, pp. 1103-1111
-
-
Marchesi, C.1
Essalmani, R.2
Lemarié, C.A.3
Leibovitz, E.4
Ebrahimian, T.5
Paradis, P.6
Seidah, N.G.7
Schiffrin, E.L.8
Prat, A.9
-
44
-
-
84866280245
-
Loss of endothelial furin leads to cardiac malformation and early postnatal death
-
Kim, W., Essalmani, R., Szumska, D., Creemers, J. W., Roebroek, A. J., D’Orleans-Juste, P., Bhattacharya, S., Seidah, N. G., and Prat, A. (2012) Loss of endothelial furin leads to cardiac malformation and early postnatal death. Mol. Cell Biol. 32, 3382–3391
-
(2012)
Mol. Cell Biol.
, vol.32
, pp. 3382-3391
-
-
Kim, W.1
Essalmani, R.2
Szumska, D.3
Creemers, J.W.4
Roebroek, A.J.5
D’Orleans-Juste, P.6
Bhattacharya, S.7
Seidah, N.G.8
Prat, A.9
-
45
-
-
20444442718
-
Mice with a severe deficiency in protein c display prothrombotic and proinflamma-tory phenotypes and compromised maternal reproductive capabilities
-
Lay, A. J., Liang, Z., Rosen, E. D., and Castellino, F. J. (2005) Mice with a severe deficiency in protein C display prothrombotic and proinflamma-tory phenotypes and compromised maternal reproductive capabilities. J. Clin. Invest. 115, 1552–1561
-
(2005)
J. Clin. Invest.
, vol.115
, pp. 1552-1561
-
-
Lay, A.J.1
Liang, Z.2
Rosen, E.D.3
Castellino, F.J.4
-
46
-
-
84903440167
-
Annexin A2 reduces pcsk9 protein levels via a translational mechanism and interacts with the M1 and M2 domains of PCSK9
-
Ly, K., Saavedra, Y. G., Canuel, M., Routhier, S., Desjardins, R., Hamelin, J., Mayne, J., Lazure, C., Seidah, N. G., and Day, R. (2014) Annexin A2 reduces PCSK9 protein levels via a translational mechanism and interacts with the M1 and M2 domains of PCSK9. J. Biol. Chem. 289, 17732–17746
-
(2014)
J. Biol. Chem.
, vol.289
, pp. 17732-17746
-
-
Ly, K.1
Saavedra, Y.G.2
Canuel, M.3
Routhier, S.4
Desjardins, R.5
Hamelin, J.6
Mayne, J.7
Lazure, C.8
Seidah, N.G.9
Day, R.10
-
47
-
-
33645237960
-
Deletion of the gene encoding proprotein convertase 5/6 causes early embryonic lethality in the mouse
-
Essalmani, R., Hamelin, J., Marcinkiewicz, J., Chamberland, A., Mbikay, M., Chrétien, M., Seidah, N. G., and Prat, A. (2006) Deletion of the gene encoding proprotein convertase 5/6 causes early embryonic lethality in the mouse. Mol. Cell Biol. 26, 354 –361
-
(2006)
Mol. Cell Biol.
, vol.26
, pp. 354-361
-
-
Essalmani, R.1
Hamelin, J.2
Marcinkiewicz, J.3
Chamberland, A.4
Mbikay, M.5
Chrétien, M.6
Seidah, N.G.7
Prat, A.8
-
48
-
-
14944364650
-
Interferences in coagulation tests: Evaluation of the 570-nm method on the dade behring bcs analyser
-
Junker, R., Käse, M., Schulte, H., Bäumer, R., Langer, C., and Nowak-Göttl, U. (2005) Interferences in coagulation tests: evaluation of the 570-nm method on the Dade Behring BCS analyser. Clin. Chem. Lab. Med. 43, 244 –252
-
(2005)
Clin. Chem. Lab. Med.
, vol.43
, pp. 244-252
-
-
Junker, R.1
Käse, M.2
Schulte, H.3
Bäumer, R.4
Langer, C.5
Nowak-Göttl, U.6
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