Integration of over 9,000 mass spectrometry experiments builds a global map of human protein complexes

Molecular Systems Biology

Volumn 13, Issue 6, 2017, Pages

  Drew, Kevin ^a   Lee, Chanjae ^a   Huizar, Ryan L ^a   Tu, Fan ^a   Borgeson, Blake ^a,c   McWhite, Claire D ^a   Ma, Yun ^a,b   Wallingford, John B ^a   Marcotte, Edward M ^a  

^a UNIVERSITY OF TEXAS AT AUSTIN   (United States)

^b THE FIRST AFFILIATED HOSPITAL OF SUN YAT SEN UNIVERSITY   (China)

^c Recursion Pharmaceuticals   (United States)

Author keywords

cilia; ciliopathy; human interactome; mass spectrometry; protein complexes; proteomics

Indexed keywords

ANKRD55 PROTEIN; CCDC138 PROTEIN; CELL PROTEIN; INITIATION FACTOR 3; KIAA1328 PROTEIN; UNCLASSIFIED DRUG; WDR90 PROTEIN; MULTIPROTEIN COMPLEX; PROTEIN;

ANIMAL EXPERIMENT; ARTICLE; CENTROSOME; CILIOPATHY; CILIUM; COMPLEX FORMATION; CONTROLLED STUDY; EMBRYO; FALSE NEGATIVE RESULT; FALSE POSITIVE RESULT; HEK293T CELL LINE; HIGH THROUGHPUT SEQUENCING; HUMAN; HUMAN CELL; IN VIVO STUDY; KINETOSOME; MASS SPECTROMETRY; MEASUREMENT ACCURACY; MEASUREMENT PRECISION; MOLECULAR BIOLOGY; NONHUMAN; PREDATOR PREY INTERACTION; PRIORITY JOURNAL; PROCESS OPTIMIZATION; PROTEIN ANALYSIS; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN PURIFICATION; PROTEIN SUBUNIT; PROTEIN SYNTHESIS; PROTEIN TRANSPORT; PROTEOMICS; QUANTITATIVE ANALYSIS; SUPPORT VECTOR MACHINE; SYNAPSE VESICLE; SYSTEMS BIOLOGY; TISSUE SPECIFICITY; UNSUPERVISED MACHINE LEARNING; XENOPUS LAEVIS; GENETIC DISORDER; GENETICS;

GENETIC DISEASES, INBORN; HUMANS; MASS SPECTROMETRY; MULTIPROTEIN COMPLEXES; PROTEIN INTERACTION MAPPING; PROTEIN TRANSPORT; PROTEINS;

EID: 85021320754     PISSN: None     EISSN: 17444292     Source Type: Journal    
DOI: 10.15252/msb.20167490     Document Type: Article

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