-
1
-
-
84934274102
-
From prescription to transcription: genome sequence as drug target
-
Guo C, DIppolito AM, Reddy TE. From prescription to transcription: genome sequence as drug target. Cell 2015; 162: 16 17.
-
(2015)
Cell
, vol.162
, pp. 1617
-
-
Guo, C1
DIppolito, AM2
Reddy, TE.3
-
2
-
-
84934325147
-
Genetic variation determines PPARgamma function and anti-diabetic drug response In Vivo
-
Soccio RE, Chen ER, Rajapurkar SR et al. Genetic variation determines PPARgamma function and anti-diabetic drug response In Vivo. Cell 2015; 162: 33 44.
-
(2015)
Cell
, vol.162
, pp. 33-44
-
-
Soccio, RE1
Chen, ER2
Rajapurkar, SR3
-
3
-
-
84899910966
-
Evidence of NLRP3-inflammasome activation in rheumatoid arthritis (RA); genetic variants within the NLRP3-inflammasome complex in relation to susceptibility to RA and response to anti-TNF treatment
-
Mathews RJ, Robinson JI, Battellino M et al. Evidence of NLRP3-inflammasome activation in rheumatoid arthritis (RA); genetic variants within the NLRP3-inflammasome complex in relation to susceptibility to RA and response to anti-TNF treatment. Ann Rheum Dis 2014; 73: 1202 1210.
-
(2014)
Ann Rheum Dis
, vol.73
, pp. 1202-1210
-
-
Mathews, RJ1
Robinson, JI2
Battellino, M3
-
4
-
-
77953919146
-
IRF5 is required for late-phase TNF secretion by human dendritic cells
-
Krausgruber T, Saliba D, Ryzhakov G et al. IRF5 is required for late-phase TNF secretion by human dendritic cells. Blood 2010; 115: 4421 4430.
-
(2010)
Blood
, vol.115
, pp. 44214430
-
-
Krausgruber, T1
Saliba, D2
Ryzhakov, G3
-
5
-
-
84899639879
-
Cytokines in inflammatory bowel disease
-
Neurath MF. Cytokines in inflammatory bowel disease. Nat Rev Immunol 2014; 14: 329 342.
-
(2014)
Nat Rev Immunol
, vol.14
, pp. 329-342
-
-
Neurath, MF.1
-
6
-
-
84868336049
-
Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease
-
Jostins L, Ripke S, Weersma RK et al. Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease. Nature 2012; 491: 119 124.
-
(2012)
Nature
, vol.491
, pp. 119-124
-
-
Jostins, L1
Ripke, S2
Weersma, RK3
-
7
-
-
45149108420
-
Mapping the genetic architecture of gene expression in human liver
-
Schadt EE, Molony C, Chudin E et al. Mapping the genetic architecture of gene expression in human liver. PLoS Biol 2008; 6: e107.
-
(2008)
PLoS Biol
, vol.6
, pp. e107
-
-
Schadt, EE1
Molony, C2
Chudin, E3
-
8
-
-
79959916375
-
A survey of the genetics of stomach, liver, and adipose gene expression from a morbidly obese cohort
-
Greenawalt DM, Dobrin R, Chudin E et al. A survey of the genetics of stomach, liver, and adipose gene expression from a morbidly obese cohort. Genome Res 2011; 21: 1008 1016.
-
(2011)
Genome Res
, vol.21
, pp. 1008-1016
-
-
Greenawalt, DM1
Dobrin, R2
Chudin, E3
-
9
-
-
84870713668
-
Lung eQTLs to help reveal the molecular underpinnings of asthma
-
Hao K, Bosse Y, Nickle DC et al. Lung eQTLs to help reveal the molecular underpinnings of asthma. PLoS Genet 2012; 8: e1003029.
-
(2012)
PLoS Genet
, vol.8
, pp. e1003029
-
-
Hao, K1
Bosse, Y2
Nickle, DC3
-
10
-
-
41349095280
-
Genetics of gene expression and its effect on disease
-
Emilsson V, Thorleifsson G, Zhang B et al. Genetics of gene expression and its effect on disease. Nature 2008; 452: 423 428.
-
(2008)
Nature
, vol.452
, pp. 423-428
-
-
Emilsson, V1
Thorleifsson, G2
Zhang, B3
-
11
-
-
84907893258
-
Genetic regulation of gene expression in the lung identifies CST3 and CD22 as potential causal genes for airflow obstruction
-
Lamontagne M, Timens W, Hao K et al. Genetic regulation of gene expression in the lung identifies CST3 and CD22 as potential causal genes for airflow obstruction. Thorax 2014; 69: 997 1004.
-
(2014)
Thorax
, vol.69
, pp. 997-1004
-
-
Lamontagne, M1
Timens, W2
Hao, K3
-
12
-
-
84901056381
-
Determining causality and consequence of expression quantitative trait loci
-
Battle A, Montgomery SB. Determining causality and consequence of expression quantitative trait loci. Hum Genet 2014; 133: 727 735.
-
(2014)
Hum Genet
, vol.133
, pp. 727-735
-
-
Battle, A1
Montgomery, SB.2
-
13
-
-
84864417548
-
Fast and accurate genotype imputation in genome-wide association studies through pre-phasing
-
Howie B, Fuchsberger C, Stephens M et al. Fast and accurate genotype imputation in genome-wide association studies through pre-phasing. Nat Genet 2012; 44: 955 959.
-
(2012)
Nat Genet
, vol.44
, pp. 955-959
-
-
Howie, B1
Fuchsberger, C2
Stephens, M3
-
14
-
-
84892385595
-
A review of post-GWAS prioritization approaches
-
Hou L, Zhao H. A review of post-GWAS prioritization approaches. Front Genet 2013; 4: 280.
-
(2013)
Front Genet
, vol.4
, pp. 280
-
-
Hou, L1
Zhao, H.2
-
15
-
-
84871701834
-
Ustekinumab induction and maintenance therapy in refractory Crohns disease
-
Sandborn WJ, Gasink C, Gao L-L et al. Ustekinumab induction and maintenance therapy in refractory Crohns disease. N Engl J Med 2012; 367: 1519 1528.
-
(2012)
N Engl J Med
, vol.367
, pp. 15191528
-
-
Sandborn, WJ1
Gasink, C2
Gao, L-L3
-
16
-
-
84886780296
-
Dynamic trans-Acting factor colocalization in human cells
-
Xie D, Boyle AP, Wu L et al. Dynamic trans-Acting factor colocalization in human cells. Cell 2013; 155: 713 724.
-
(2013)
Cell
, vol.155
, pp. 713-724
-
-
Xie, D1
Boyle, AP2
Wu, L3
-
17
-
-
84878289023
-
Expression quantitative trait loci analysis identifies associations between genotype and gene expression in human intestine
-
1496.e1-3
-
Kabakchiev B, Silverberg MS. Expression quantitative trait loci analysis identifies associations between genotype and gene expression in human intestine. Gastroenterology 2013; 144: 1488 1496, 1496.e1-3.
-
(2013)
Gastroenterology
, vol.144
, Issue.1488 1496
-
-
Kabakchiev, B1
Silverberg, MS.2
-
18
-
-
67249117049
-
Potential etiologic and functional implications of genome-wide association loci for human diseases and traits
-
Hindorff LA, Sethupathy P, Junkins HA et al. Potential etiologic and functional implications of genome-wide association loci for human diseases and traits. Proc Natl Acad Sci USA 2009; 106: 9362 9367.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 93629367
-
-
Hindorff, LA1
Sethupathy, P2
Junkins, HA3
-
19
-
-
77956242566
-
Quality control and quality assurance in genotypic data for genome-wide association studies
-
Laurie CC, Doheny KF, Mirel DB et al. Quality control and quality assurance in genotypic data for genome-wide association studies. Genet Epidemiol 2010; 34: 591 602.
-
(2010)
Genet Epidemiol
, vol.34
, pp. 591-602
-
-
Laurie, CC1
Doheny, KF2
Mirel, DB3
-
20
-
-
84891790401
-
The NHGRI GWAS Catalog, a curated resource of SNP-Trait associations
-
Welter D, MacArthur J, Morales J et al. The NHGRI GWAS Catalog, a curated resource of SNP-Trait associations. Nucleic Acids Res 2014; 42: D1001 D1006.
-
(2014)
Nucleic Acids Res
, vol.42
, pp. D1001D1006
-
-
Welter, D1
MacArthur, J2
Morales, J3
-
21
-
-
77957113600
-
A large-scale, consortium-based genomewide association study of asthma
-
Moffatt MF, Gut IG, Demenais F et al. A large-scale, consortium-based genomewide association study of asthma. N Engl J Med 2010; 363: 1211 1221.
-
(2010)
N Engl J Med
, vol.363
, pp. 1211-1221
-
-
Moffatt, MF1
Gut, IG2
Demenais, F3
-
22
-
-
84963838559
-
Airway epithelial expression quantitative trait loci reveal genes underlying asthma and other airway diseases
-
Luo W, Obeidat M, Di Narzo AF et al. Airway epithelial expression quantitative trait loci reveal genes underlying asthma and other airway diseases. Am J Respir Cell Mol Biol 2016; 54: 177 187.
-
(2016)
Am J Respir Cell Mol Biol
, vol.54
, pp. 177-187
-
-
Luo, W1
Obeidat, M2
Di Narzo, AF3
-
23
-
-
84878764878
-
Next generation exome sequencing of paediatric inflammatory bowel disease patients identifies rare and novel variants in candidate genes
-
Christodoulou K, Wiskin AE, Gibson J et al. Next generation exome sequencing of paediatric inflammatory bowel disease patients identifies rare and novel variants in candidate genes. Gut 2013; 62: 977 984.
-
(2013)
Gut
, vol.62
, pp. 977-984
-
-
Christodoulou, K1
Wiskin, AE2
Gibson, J3
-
24
-
-
84891780319
-
The Gene Expression Barcode 3.0: improved data processing and mining tools
-
McCall MN, Jaffee HA, Zelisko SJ et al. The Gene Expression Barcode 3.0: improved data processing and mining tools. Nucleic Acids Res 2014; 42: D938 D943.
-
(2014)
Nucleic Acids Res
, vol.42
, pp. D938D943
-
-
McCall, MN1
Jaffee, HA2
Zelisko, SJ3
-
25
-
-
84883772859
-
Induced and natural regulatory T cells in the development of inflammatory bowel disease
-
Mayne CG, Williams CB. Induced and natural regulatory T cells in the development of inflammatory bowel disease. Inflamm Bowel Dis 2013; 19: 1772 1788.
-
(2013)
Inflamm Bowel Dis
, vol.19
, pp. 17721788
-
-
Mayne, CG1
Williams, CB.2
-
26
-
-
84887421132
-
Monogenic diseases associated with intestinal inflammation: implications for the understanding of inflammatory bowel disease
-
Uhlig HH. Monogenic diseases associated with intestinal inflammation: implications for the understanding of inflammatory bowel disease. Gut 2013; 62: 1795 1805.
-
(2013)
Gut
, vol.62
, pp. 17951805
-
-
Uhlig, HH.1
-
27
-
-
84877044428
-
MAIT cells, surveyors of a new class of antigen: development and functions
-
Le Bourhis L, Mburu YK, Lantz O. MAIT cells, surveyors of a new class of antigen: development and functions. Curr Opin Immunol 2013; 25: 174 180.
-
(2013)
Curr Opin Immunol
, vol.25
, pp. 174-180
-
-
Le Bourhis, L1
Mburu, YK2
Lantz, O.3
-
28
-
-
84897937905
-
Innate mucosal-Associated invariant T (MAIT) cells are activated in inflammatory bowel diseases
-
Serriari NE, Eoche M, Lamotte L et al. Innate mucosal-Associated invariant T (MAIT) cells are activated in inflammatory bowel diseases. Clini Expe Immunol 2014; 176: 266 274.
-
(2014)
Clini Expe Immunol
, vol.176
, pp. 266-274
-
-
Serriari, NE1
Eoche, M2
Lamotte, L3
-
29
-
-
77952588387
-
New insights into the genetic control of gene expression using a Bayesian multi-Tissue approach
-
Petretto E, Bottolo L, Langley SR et al. New insights into the genetic control of gene expression using a Bayesian multi-Tissue approach. PLoS Comput Biol 2010; 6: e1000737.
-
(2010)
PLoS Comput Biol
, vol.6
, pp. e1000737
-
-
Petretto, E1
Bottolo, L2
Langley, SR3
-
30
-
-
84923864092
-
Meta-eQTL: A tool set for flexible eQTL meta-Analysis
-
Di Narzo A, Cheng H, Lu J et al. Meta-eQTL: A tool set for flexible eQTL meta-Analysis. BMC Bioinformatics 2014; 15: 392.
-
(2014)
BMC Bioinformatics
, vol.15
, pp. 392
-
-
Di Narzo, A1
Cheng, H2
Lu, J3
-
31
-
-
84879653976
-
Effectively identifying eQTLs from multiple tissues by combining mixed model and meta-Analytic approaches
-
Sul JH, Han B, Ye C et al. Effectively identifying eQTLs from multiple tissues by combining mixed model and meta-Analytic approaches. PLoS Genet 2013; 9: e1003491.
-
(2013)
PLoS Genet
, vol.9
, pp. e1003491
-
-
Sul, JH1
Han, B2
Ye, C3
-
32
-
-
84878476783
-
A statistical framework for joint eQTL analysis in multiple tissues
-
Flutre T, Wen X, Pritchard J et al. A statistical framework for joint eQTL analysis in multiple tissues. PLoS Genet 2013; 9: e1003486.
-
(2013)
PLoS Genet
, vol.9
, pp. e1003486
-
-
Flutre, T1
Wen, X2
Pritchard, J3
-
33
-
-
84927716096
-
Characterization of expression quantitative trait loci in the human colon
-
Singh T, Levine AP, Smith PJ et al. Characterization of expression quantitative trait loci in the human colon. Inflamm Bowel Dis 2015; 21: 251 256.
-
(2015)
Inflamm Bowel Dis
, vol.21
, pp. 251-256
-
-
Singh, T1
Levine, AP2
Smith, PJ3
-
34
-
-
84928751590
-
Enrichment of inflammatory bowel disease and colorectal cancer risk variants in colon expression quantitative trait loci
-
Hulur I, Gamazon ER, Skol AD et al. Enrichment of inflammatory bowel disease and colorectal cancer risk variants in colon expression quantitative trait loci. BMC Genom 2015; 16: 138.
-
(2015)
BMC Genom
, vol.16
, pp. 138
-
-
Hulur, I1
Gamazon, ER2
Skol, AD3
-
35
-
-
59449097277
-
Matrix metalloproteinase-9-mediated tissue injury overrides the protective effect of matrix metalloproteinase-2 during colitis
-
Garg P, Vijay-Kumar M, Wang L et al. Matrix metalloproteinase-9-mediated tissue injury overrides the protective effect of matrix metalloproteinase-2 during colitis. AM J Physiol Gastrointest Liver Physiol 2009; 296: G175 G184.
-
(2009)
AM J Physiol Gastrointest Liver Physiol
, vol.296
, pp. G175G184
-
-
Garg, P1
Vijay-Kumar, M2
Wang, L3
-
36
-
-
84869121252
-
TspanC8 tetraspanins regulate ADAM10/ Kuzbanian trafficking and promote Notch activation in flies and mammals
-
Dornier E, Coumailleau F, Ottavi JF et al. TspanC8 tetraspanins regulate ADAM10/ Kuzbanian trafficking and promote Notch activation in flies and mammals. J Cell Biol 2012; 199: 481 496.
-
(2012)
J Cell Biol
, vol.199
, pp. 481-496
-
-
Dornier, E1
Coumailleau, F2
Ottavi, JF3
-
37
-
-
84921645972
-
ADAM10 regulates Notch function in intestinal stem cells of mice
-
822 834.e13
-
Tsai YH, VanDussen KL, Sawey ET et al. ADAM10 regulates Notch function in intestinal stem cells of mice. Gastroenterology 2014; 147: 822 834.e13.
-
(2014)
Gastroenterology
, vol.147
-
-
Tsai, YH1
VanDussen, KL2
Sawey, ET3
-
38
-
-
84886734590
-
Upregulation of adenylate cyclase 3 (ADCY3) increases the tumorigenic potential of cells by activating the CREB pathway
-
Hong SH, Goh SH, Lee SJ et al. Upregulation of adenylate cyclase 3 (ADCY3) increases the tumorigenic potential of cells by activating the CREB pathway. Oncotarget 2013; 4: 1791 1803.
-
(2013)
Oncotarget
, vol.4
, pp. 17911803
-
-
Hong, SH1
Goh, SH2
Lee, SJ3
-
40
-
-
33644844840
-
A novel mutation in the dihydrolipoamide dehydrogenase E3 subunit gene (DLD) resulting in an atypical form of alpha-ketoglutarate dehydrogenase deficiency
-
Odievre MH, Chretien D, Munnich A et al. A novel mutation in the dihydrolipoamide dehydrogenase E3 subunit gene (DLD) resulting in an atypical form of alpha-ketoglutarate dehydrogenase deficiency. Hum Mutat 2005; 25: 323 324.
-
(2005)
Hum Mutat
, vol.25
, pp. 323-324
-
-
Odievre, MH1
Chretien, D2
Munnich, A3
-
41
-
-
84897955962
-
Dihydrolipoamide dehydrogenase (DLD) deficiency in a Spanish patient with myopathic presentation due to a new mutation in the interface domain
-
(Suppl 3)
-
Quintana E, Pineda M, Font A et al. Dihydrolipoamide dehydrogenase (DLD) deficiency in a Spanish patient with myopathic presentation due to a new mutation in the interface domain. J Inherit Metab Dis 2010; 33 (Suppl 3): S315 S319.
-
(2010)
J Inherit Metab Dis
, vol.33
, pp. S315S319
-
-
Quintana, E1
Pineda, M2
Font, A3
-
42
-
-
10444279579
-
D-lactic acidosis in short-bowel syndrome managed with antibiotics and probiotics
-
Uchida H, Yamamoto H, Kisaki Y et al. D-lactic acidosis in short-bowel syndrome managed with antibiotics and probiotics. J Pediatr Surg 2004; 39: 634 636.
-
(2004)
J Pediatr Surg
, vol.39
, pp. 634-636
-
-
Uchida, H1
Yamamoto, H2
Kisaki, Y3
-
44
-
-
84902652055
-
Regulated expression of leukocyte-specific transcript (LST) 1 in human intestinal inflammation
-
Heidemann J, Kebschull M, Tepasse PR et al. Regulated expression of leukocyte-specific transcript (LST) 1 in human intestinal inflammation. Inflamm Res 2014; 63: 513 517.
-
(2014)
Inflamm Res
, vol.63
, pp. 513-517
-
-
Heidemann, J1
Kebschull, M2
Tepasse, PR3
-
45
-
-
84876322075
-
LST1 promotes the assembly of a molecular machinery responsible for tunneling nanotube formation
-
Schiller C, Diakopoulos KN, Rohwedder I et al. LST1 promotes the assembly of a molecular machinery responsible for tunneling nanotube formation. J Cell Sci 2013; 126: 767 777.
-
(2013)
J Cell Sci
, vol.126
, pp. 767-777
-
-
Schiller, C1
Diakopoulos, KN2
Rohwedder, I3
-
46
-
-
79951671510
-
IRF5 promotes inflammatory macrophage polarization and TH1-TH17 responses
-
Krausgruber T, Blazek K, Smallie T et al. IRF5 promotes inflammatory macrophage polarization and TH1-TH17 responses. Nat Immunol 2011; 12: 231 238.
-
(2011)
Nat Immunol
, vol.12
, pp. 231-238
-
-
Krausgruber, T1
Blazek, K2
Smallie, T3
-
47
-
-
85122967220
-
P052 Allograft inflammatory factor-1 (AIF-1) stimulates Th1 differentiation of human T-cells and protects them from apoptosis
-
(Suppl 1)
-
Cano-Martinez D. P052 Allograft inflammatory factor-1 (AIF-1) stimulates Th1 differentiation of human T-cells and protects them from apoptosis. J Chrons Colitis 2015;9 (Suppl 1): S103.
-
(2015)
J Chrons Colitis
, vol.9
, pp. S103
-
-
Cano-Martinez, D.1
-
48
-
-
56349124824
-
TM9SF4 is required for Drosophila cellular immunity via cell adhesion and phagocytosis
-
Bergeret E, Perrin J, Williams M et al. TM9SF4 is required for Drosophila cellular immunity via cell adhesion and phagocytosis. J Cell Sci 2008; 121: 3325 3334.
-
(2008)
J Cell Sci
, vol.121
, pp. 3325-3334
-
-
Bergeret, E1
Perrin, J2
Williams, M3
-
49
-
-
84865361745
-
GSDMB/ORMDL3 variants contribute to asthma susceptibility and eosinophil-mediated bronchial hyperresponsiveness
-
Kang MJ, Yu HS, Seo JH et al. GSDMB/ORMDL3 variants contribute to asthma susceptibility and eosinophil-mediated bronchial hyperresponsiveness. Hum Immunol 2012; 73: 954 959.
-
(2012)
Hum Immunol
, vol.73
, pp. 954-959
-
-
Kang, MJ1
Yu, HS2
Seo, JH3
-
50
-
-
84884928688
-
ORMDL3 promotes eosinophil trafficking and activation via regulation of integrins and CDNat
-
Ha SG, Ge XN, Bahaie NS et al. ORMDL3 promotes eosinophil trafficking and activation via regulation of integrins and CDNat Commun 2013; 4: 2479.
-
(2013)
Commun
, vol.4
, pp. 2479
-
-
Ha, SG1
Ge, XN2
Bahaie, NS3
-
51
-
-
84898981029
-
Intelectin-1 is a prominent protein constituent of pathologic mucus associated with eosinophilic airway inflammation in asthma
-
Kerr SC, Carrington SD, Oscarson S et al. Intelectin-1 is a prominent protein constituent of pathologic mucus associated with eosinophilic airway inflammation in asthma. Am J Respir Criti Care Med 2014; 189: 1005 1007.
-
(2014)
Am J Respir Criti Care Med
, vol.189
, pp. 1005-1007
-
-
Kerr, SC1
Carrington, SD2
Oscarson, S3
-
52
-
-
84925688608
-
Opposite effects of interferon regulatory factor 1 and osteopontin on the apoptosis of epithelial cells induced by TNF-Alpha in inflammatory bowel disease
-
Tang R, Yang G, Zhang S et al. Opposite effects of interferon regulatory factor 1 and osteopontin on the apoptosis of epithelial cells induced by TNF-Alpha in inflammatory bowel disease. Inflamm Bowel Dis 2014; 20: 1950 1961.
-
(2014)
Inflamm Bowel Dis
, vol.20
, pp. 19501961
-
-
Tang, R1
Yang, G2
Zhang, S3
-
53
-
-
84878916447
-
Multiple activating and repressive cis-promoter regions regulate TNFSF15 expression in human primary mononuclear cells
-
Gonsky R, Deem RL, Targan SR. Multiple activating and repressive cis-promoter regions regulate TNFSF15 expression in human primary mononuclear cells. Cytokine 2013; 63: 36 42.
-
(2013)
Cytokine
, vol.63
, pp. 36-42
-
-
Gonsky, R1
Deem, RL2
Targan, SR.3
-
54
-
-
43149097171
-
Characterization of Cullin-box sequences that direct recruitment of Cul2-Rbx1 and Cul5-Rbx2 modules to Elongin BC-based ubiquitin ligases
-
Mahrour N, Redwine WB, Florens L et al. Characterization of Cullin-box sequences that direct recruitment of Cul2-Rbx1 and Cul5-Rbx2 modules to Elongin BC-based ubiquitin ligases. J Biol Chem 2008; 283: 8005 8013.
-
(2008)
J Biol Chem
, vol.283
, pp. 80058013
-
-
Mahrour, N1
Redwine, WB2
Florens, L3
-
55
-
-
64349114240
-
GCN5 is a required cofactor for a ubiquitin ligase that targets NFkappaB/ RelA
-
Mao X, Gluck N, Li D et al. GCN5 is a required cofactor for a ubiquitin ligase that targets NFkappaB/ RelA. Genes Dev 2009; 23: 849 861.
-
(2009)
Genes Dev
, vol.23
, pp. 849-861
-
-
Mao, X1
Gluck, N2
Li, D3
-
56
-
-
84905441090
-
DNMT3L interacts with transcription factors to target DNMT3L/DNMT3B to specific DNA sequences: role of the DNMT3L/DNMT3B/p65-NFkappaB complex in the (de-)methylation of
-
Pacaud R, Sery Q, Oliver L et al. DNMT3L interacts with transcription factors to target DNMT3L/DNMT3B to specific DNA sequences: role of the DNMT3L/DNMT3B/p65-NFkappaB complex in the (de-)methylation of TRAFBiochimie 2014; 104: 36 49.
-
(2014)
TRAFBiochimie
, vol.104
, pp. 36-49
-
-
Pacaud, R1
Sery, Q2
Oliver, L3
-
57
-
-
84876437239
-
Gene expression of tumor necrosis factor receptor associatedfactor (TRAF)-1 and TRAF-2 in inflammatory bowel disease
-
Qiao YQ, Shen J, Gu Y et al. Gene expression of tumor necrosis factor receptor associatedfactor (TRAF)-1 and TRAF-2 in inflammatory bowel disease. J Digest Dis 2013; 14: 244 250.
-
(2013)
J Digest Dis
, vol.14
, pp. 244-250
-
-
Qiao, YQ1
Shen, J2
Gu, Y3
-
58
-
-
77955362763
-
Analysis of SNPs with an effect on gene expression identifies UBE2L3 and BCL3 as potential new risk genes for Crohns disease
-
Fransen K, Visschedijk MC, van Sommeren S et al. Analysis of SNPs with an effect on gene expression identifies UBE2L3 and BCL3 as potential new risk genes for Crohns disease. Hum Mol Genet 2010; 19: 3482 3488.
-
(2010)
Hum Mol Genet
, vol.19
, pp. 3482-3488
-
-
Fransen, K1
Visschedijk, MC2
van Sommeren, S3
-
59
-
-
84897626276
-
The ubiquitin conjugating enzyme UBE2L3 regulates TNFalphainduced linear ubiquitination
-
Fu B, Li S, Wang L et al. The ubiquitin conjugating enzyme UBE2L3 regulates TNFalphainduced linear ubiquitination. Cell Res 2014; 24: 376 379.
-
(2014)
Cell Res
, vol.24
, pp. 376-379
-
-
Fu, B1
Li, S2
Wang, L3
-
60
-
-
80053912078
-
Acylpeptide hydrolase inhibition as targeted strategy to induce proteasomal down-regulation
-
Palmieri G, Bergamo P, Luini A et al. Acylpeptide hydrolase inhibition as targeted strategy to induce proteasomal down-regulation. PloS One 2011; 6: e25888.
-
(2011)
PloS One
, vol.6
, pp. e25888
-
-
Palmieri, G1
Bergamo, P2
Luini, A3
-
61
-
-
84889645158
-
Inositol polyphosphate multikinase is a coactivator for serum response factor-dependent induction of immediate early genes
-
Kim E, Tyagi R, Lee JY et al. Inositol polyphosphate multikinase is a coactivator for serum response factor-dependent induction of immediate early genes. Proc Natl Acad Sci USA 2013; 110: 19938 19943.
-
(2013)
Proc Natl Acad Sci USA
, vol.110
, pp. 1993819943
-
-
Kim, E1
Tyagi, R2
Lee, JY3
-
62
-
-
0036144377
-
TGF-beta induces apoptosis through Smad-mediated expression of DAP-kinase
-
Jang CW, Chen CH, Chen CC et al. TGF-beta induces apoptosis through Smad-mediated expression of DAP-kinase. Nature Cell Biol 2002; 4: 51 58.
-
(2002)
Nature Cell Biol
, vol.4
, pp. 5158
-
-
Jang, CW1
Chen, CH2
Chen, CC3
-
63
-
-
84877344662
-
The NLR protein, NLRX1, and its partner, TUFM, reduce type I interferon, and enhance autophagy
-
Lei Y, Wen H, Ting JP. The NLR protein, NLRX1, and its partner, TUFM, reduce type I interferon, and enhance autophagy. Autophagy 2013; 9: 432 433.
-
(2013)
Autophagy
, vol.9
, pp. 432-433
-
-
Lei, Y1
Wen, H2
Ting, JP.3
-
64
-
-
84884329320
-
PRKCB/protein kinase C, beta and the mitochondrial axis as key regulators of autophagy
-
Patergnani S, Marchi S, Rimessi A et al. PRKCB/protein kinase C, beta and the mitochondrial axis as key regulators of autophagy. Autophagy 2013; 9: 1367 1385.
-
(2013)
Autophagy
, vol.9
, pp. 1367-1385
-
-
Patergnani, S1
Marchi, S2
Rimessi, A3
-
65
-
-
84908053092
-
The microtubule-Associated protein EB1 links AIM2 inflammasomes with autophagy-dependent secretion
-
Wang LJ, Huang HY, Huang MP et al. The microtubule-Associated protein EB1 links AIM2 inflammasomes with autophagy-dependent secretion. J Biol Chem 2014; 289: 29322 29333.
-
(2014)
J Biol Chem
, vol.289
, pp. 2932229333
-
-
Wang, LJ1
Huang, HY2
Huang, MP3
-
66
-
-
84906241388
-
Interaction between NOD2 and CARD9 involves the NOD2 NACHTand the linker region between the NOD2 CARDs and NACHT domain
-
Parkhouse R, Boyle JP, Mayle S et al. Interaction between NOD2 and CARD9 involves the NOD2 NACHTand the linker region between the NOD2 CARDs and NACHT domain. FEBS Lett 2014; 588: 2830 2836.
-
(2014)
FEBS Lett
, vol.588
, pp. 2830-2836
-
-
Parkhouse, R1
Boyle, JP2
Mayle, S3
-
67
-
-
84883144028
-
Card9 mediates intestinal epithelial cell restitution, T-helper 17 responses, and control of bacterial infection in mice
-
591 601.e3
-
Sokol H, Conway KL, Zhang M et al. Card9 mediates intestinal epithelial cell restitution, T-helper 17 responses, and control of bacterial infection in mice. Gastroenterology 2013; 145: 591 601.e3.
-
(2013)
Gastroenterology
, vol.145
-
-
Sokol, H1
Conway, KL2
Zhang, M3
-
68
-
-
80655149205
-
New IBD genetics: common pathways with other diseases
-
Lees CW, Barrett JC, Parkes M et al. New IBD genetics: common pathways with other diseases. Gut 2011; 60: 1739 1753.
-
(2011)
Gut
, vol.60
, pp. 17391753
-
-
Lees, CW1
Barrett, JC2
Parkes, M3
-
69
-
-
84867581318
-
Mucosal genome-wide methylation changes in inflammatory bowel disease
-
Cooke J, Zhang H, Greger L et al. Mucosal genome-wide methylation changes in inflammatory bowel disease. Inflamm Bowel Dis 2012; 18: 2128 2137.
-
(2012)
Inflamm Bowel Dis
, vol.18
, pp. 2128-2137
-
-
Cooke, J1
Zhang, H2
Greger, L3
-
70
-
-
84880730339
-
A dual role for SAGA-Associated factor 29 (SGF29) in ER stress survival by coordination of both histone H3 acetylation and histone H3 lysine-4 trimethylation
-
Schram AW, Baas R, Jansen PW et al. A dual role for SAGA-Associated factor 29 (SGF29) in ER stress survival by coordination of both histone H3 acetylation and histone H3 lysine-4 trimethylation. PloS One 2013; 8: e70035.
-
(2013)
PloS One
, vol.8
, pp. e70035
-
-
Schram, AW1
Baas, R2
Jansen, PW3
-
71
-
-
10644278931
-
2B4 (CD244) is a non-MHC binding receptor with multiple functions on natural killer cells and CD8+ T cells
-
McNerney ME, Lee KM, Kumar V. 2B4 (CD244) is a non-MHC binding receptor with multiple functions on natural killer cells and CD8+ T cells. Mol Immunol 2005; 42: 489 494.
-
(2005)
Mol Immunol
, vol.42
, pp. 489-494
-
-
McNerney, ME1
Lee, KM2
Kumar, V.3
-
72
-
-
84897046940
-
Quantitative proteomics analysis of signalosome dynamics in primary T cells identifies the surface receptor CD6 as a Lat adaptor-independent TCR signaling hub
-
Roncagalli R, Hauri S, Fiore F et al. Quantitative proteomics analysis of signalosome dynamics in primary T cells identifies the surface receptor CD6 as a Lat adaptor-independent TCR signaling hub. Nat Immunol 2014; 15: 384 392.
-
(2014)
Nat Immunol
, vol.15
, pp. 384-392
-
-
Roncagalli, R1
Hauri, S2
Fiore, F3
-
73
-
-
84927691193
-
Human treg cells are characterized by low/negative CD6 expression
-
Garcia Santana CA, Tung JW, Gulnik S. Human treg cells are characterized by low/negative CD6 expression. Cytometry A 2014; 85: 901 908.
-
(2014)
Cytometry A
, vol.85
, pp. 901-908
-
-
Garcia Santana, CA1
Tung, JW2
Gulnik, S.3
-
74
-
-
84893856193
-
Ndfip1 mediates peripheral tolerance to self and exogenous antigen by inducing cell cycle exit in responding CD4+ T cells
-
Altin JA, Daley SR, Howitt J et al. Ndfip1 mediates peripheral tolerance to self and exogenous antigen by inducing cell cycle exit in responding CD4+ T cells. Proc Natl Acad Sci USA 2014; 111: 2067 2074.
-
(2014)
Proc Natl Acad Sci USA
, vol.111
, pp. 2067-2074
-
-
Altin, JA1
Daley, SR2
Howitt, J3
-
75
-
-
83855160777
-
TGF-beta induces the expression of the adaptor Ndfip1 to silence IL-4 production during iTreg cell differentiation
-
Beal AM, Ramos-Hernandez N, Riling CR et al. TGF-beta induces the expression of the adaptor Ndfip1 to silence IL-4 production during iTreg cell differentiation. Nat Immunol 2012; 13: 77 85.
-
(2012)
Nat Immunol
, vol.13
, pp. 77-85
-
-
Beal, AM1
Ramos-Hernandez, N2
Riling, CR3
-
76
-
-
78649699779
-
ZNF300, a recently identified human transcription factor, activates the human IL-2Rbeta promoter through the overlapping ZNF300/EGR1 binding site
-
Xue L, Qiu H, Ma J et al. ZNF300, a recently identified human transcription factor, activates the human IL-2Rbeta promoter through the overlapping ZNF300/EGR1 binding site. Cell Mol Biol Lett 2010; 15: 530 540.
-
(2010)
Cell Mol Biol Lett
, vol.15
, pp. 530-540
-
-
Xue, L1
Qiu, H2
Ma, J3
-
77
-
-
84896520514
-
FRA2 is a STAT5 target gene regulated by IL-2 in human CD4 T cells
-
Rani A, Greenlaw R, Runglall M et al. FRA2 is a STAT5 target gene regulated by IL-2 in human CD4 T cells. PloS One 2014; 9: e90370.
-
(2014)
PloS One
, vol.9
, pp. e90370
-
-
Rani, A1
Greenlaw, R2
Runglall, M3
-
78
-
-
84867581744
-
A validated regulatory network for Th17 cell specification
-
Ciofani M, Madar A, Galan C et al. A validated regulatory network for Th17 cell specification. Cell 2012; 151: 289 303.
-
(2012)
Cell
, vol.151
, pp. 289-303
-
-
Ciofani, M1
Madar, A2
Galan, C3
-
79
-
-
84927646479
-
CCDC88B is a novel regulator of maturation and effector functions of T cells during pathological inflammation
-
Kennedy JM, Fodil N, Torre S et al. CCDC88B is a novel regulator of maturation and effector functions of T cells during pathological inflammation. J Exp Med 2014; 211: 2519 2535.
-
(2014)
J Exp Med
, vol.211
, pp. 2519-2535
-
-
Kennedy, JM1
Fodil, N2
Torre, S3
-
80
-
-
84871416070
-
ZFP36L1 negatively regulates plasmacytoid differentiation of BCL1 cells by targeting BLIMP1 mRNA
-
Nasir A, Norton JD, Baou M et al. ZFP36L1 negatively regulates plasmacytoid differentiation of BCL1 cells by targeting BLIMP1 mRNA. PloS One 2012; 7: e52187
-
(2012)
PloS One
, vol.7
, pp. e52187
-
-
Nasir, A1
Norton, JD2
Baou, M3
|