-
1
-
-
84893702846
-
NOD proteins: Regulators of inflammation in health and disease
-
D.J. Philpott et al. NOD proteins: regulators of inflammation in health and disease Nat. Rev. Immunol. 14 2014 9 23
-
(2014)
Nat. Rev. Immunol.
, vol.14
, pp. 9-23
-
-
Philpott, D.J.1
-
2
-
-
84874234544
-
NLR activation takes a direct route
-
T.P. Monie NLR activation takes a direct route Trends Biochem. Sci. 38 2013 131 139
-
(2013)
Trends Biochem. Sci.
, vol.38
, pp. 131-139
-
-
Monie, T.P.1
-
3
-
-
84863336565
-
Pathogen sensing by nucleotide-binding oligomerization domain-containing protein 2 (NOD2) is mediated by direct binding to muramyl dipeptide and ATP
-
J. Mo et al. Pathogen sensing by nucleotide-binding oligomerization domain-containing protein 2 (NOD2) is mediated by direct binding to muramyl dipeptide and ATP J. Biol. Chem. 287 2012 23057 23067
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 23057-23067
-
-
Mo, J.1
-
4
-
-
84865434771
-
The innate immune protein Nod2 binds directly to MDP, a bacterial cell wall fragment
-
C.L. Grimes et al. The innate immune protein Nod2 binds directly to MDP, a bacterial cell wall fragment J. Am. Chem. Soc. 134 2012 13535 13537
-
(2012)
J. Am. Chem. Soc.
, vol.134
, pp. 13535-13537
-
-
Grimes, C.L.1
-
5
-
-
80052230551
-
L-Ala-γ-d-Glu-meso-diaminopimelic acid (DAP) interacts directly with leucine-rich region domain of nucleotide-binding oligomerization domain 1, increasing phosphorylation activity of receptor-interacting serine/threonine- protein kinase 2 and its interaction with nucleotide-binding oligomerization domain containing 1
-
H. Laroui et al. l-Ala-γ-d-Glu-meso-diaminopimelic acid (DAP) interacts directly with leucine-rich region domain of nucleotide-binding oligomerization domain 1, increasing phosphorylation activity of receptor-interacting serine/threonine-protein kinase 2 and its interaction with nucleotide-binding oligomerization domain containing 1 J. Biol. Chem. 286 2011 31003 31013
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 31003-31013
-
-
Laroui, H.1
-
6
-
-
22244465576
-
Membrane recruitment of NOD2 in intestinal epithelial cells is essential for nuclear factor-{kappa}B activation in muramyl dipeptide recognition
-
N. Barnich et al. Membrane recruitment of NOD2 in intestinal epithelial cells is essential for nuclear factor-{kappa}B activation in muramyl dipeptide recognition J. Cell Biol. 170 2005 21 26
-
(2005)
J. Cell Biol.
, vol.170
, pp. 21-26
-
-
Barnich, N.1
-
7
-
-
38049177193
-
The pattern-recognition molecule Nod1 is localized at the plasma membrane at sites of bacterial interaction
-
T.A. Kufer et al. The pattern-recognition molecule Nod1 is localized at the plasma membrane at sites of bacterial interaction Cell. Microbiol. 10 2008 477 486
-
(2008)
Cell. Microbiol.
, vol.10
, pp. 477-486
-
-
Kufer, T.A.1
-
8
-
-
28844448136
-
A role for Erbin in the regulation of Nod2-dependent NF-kappaB signaling
-
C. McDonald et al. A role for Erbin in the regulation of Nod2-dependent NF-kappaB signaling J. Biol. Chem. 280 2005 40301 40309
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 40301-40309
-
-
McDonald, C.1
-
9
-
-
34447504037
-
The NOD2-RICK complex signals from the plasma membrane
-
P. Lécine et al. The NOD2-RICK complex signals from the plasma membrane J. Biol. Chem. 282 2007 15197 15207
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 15197-15207
-
-
Lécine, P.1
-
10
-
-
33747036397
-
Card9 controls a non-TLR signalling pathway for innate anti-fungal immunity
-
O. Gross et al. Card9 controls a non-TLR signalling pathway for innate anti-fungal immunity Nature 442 2006 651 656
-
(2006)
Nature
, vol.442
, pp. 651-656
-
-
Gross, O.1
-
11
-
-
60549104110
-
Differential use of CARD9 by dectin-1 in macrophages and dendritic cells
-
H.S. Goodridge et al. Differential use of CARD9 by dectin-1 in macrophages and dendritic cells J. Immunol. 182 2009 1146 1154
-
(2009)
J. Immunol.
, vol.182
, pp. 1146-1154
-
-
Goodridge, H.S.1
-
12
-
-
84863393017
-
Syk kinase-coupled C-type lectin receptors engage protein kinase C-σ to elicit Card9 adaptor-mediated innate immunity
-
D. Strasser et al. Syk kinase-coupled C-type lectin receptors engage protein kinase C-σ to elicit Card9 adaptor-mediated innate immunity Immunity 36 2012 32 42
-
(2012)
Immunity
, vol.36
, pp. 32-42
-
-
Strasser, D.1
-
13
-
-
34249048617
-
The adaptor protein CARD9 is essential for the activation of myeloid cells through ITAM-associated and Toll-like receptors
-
H. Hara et al. The adaptor protein CARD9 is essential for the activation of myeloid cells through ITAM-associated and Toll-like receptors Nat. Immunol. 8 2007 619 629
-
(2007)
Nat. Immunol.
, vol.8
, pp. 619-629
-
-
Hara, H.1
-
14
-
-
74049126045
-
Recognition of RNA virus by RIG-I results in activation of CARD9 and inflammasome signaling for interleukin 1 beta production
-
H. Poeck et al. Recognition of RNA virus by RIG-I results in activation of CARD9 and inflammasome signaling for interleukin 1 beta production Nat. Immunol. 11 2010 63 69
-
(2010)
Nat. Immunol.
, vol.11
, pp. 63-69
-
-
Poeck, H.1
-
15
-
-
70350545720
-
A homozygous CARD9 mutation in a family with susceptibility to fungal infections
-
E.-O. Glocker et al. A homozygous CARD9 mutation in a family with susceptibility to fungal infections N. Engl. J. Med. 361 2009 1727 1735
-
(2009)
N. Engl. J. Med.
, vol.361
, pp. 1727-1735
-
-
Glocker, E.-O.1
-
16
-
-
34249026701
-
Syk- and CARD9-dependent coupling of innate immunity to the induction of T helper cells that produce interleukin 17
-
S. LeibundGut-Landmann et al. Syk- and CARD9-dependent coupling of innate immunity to the induction of T helper cells that produce interleukin 17 Nat. Immunol. 8 2007 630 638
-
(2007)
Nat. Immunol.
, vol.8
, pp. 630-638
-
-
Leibundgut-Landmann, S.1
-
17
-
-
33846469538
-
The adaptor protein CARD9 is required for innate immune responses to intracellular pathogens
-
Y.-M.S. Hsu et al. The adaptor protein CARD9 is required for innate immune responses to intracellular pathogens Nat. Immunol. 8 2007 198 205
-
(2007)
Nat. Immunol.
, vol.8
, pp. 198-205
-
-
Hsu, Y.-M.S.1
-
18
-
-
42749096082
-
Genetic analysis of innate immunity in Crohn's disease and ulcerative colitis identifies two susceptibility loci harboring CARD9 and IL18RAP
-
A. Zhernakova et al. Genetic analysis of innate immunity in Crohn's disease and ulcerative colitis identifies two susceptibility loci harboring CARD9 and IL18RAP Am. J. Hum. Genet. 82 2008 1202 1210
-
(2008)
Am. J. Hum. Genet.
, vol.82
, pp. 1202-1210
-
-
Zhernakova, A.1
-
19
-
-
0035978533
-
A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease
-
Y. Ogura et al. A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease Nature 411 2001 603 606
-
(2001)
Nature
, vol.411
, pp. 603-606
-
-
Ogura, Y.1
-
20
-
-
80053337957
-
The death-fold superfamily of homotypic interaction motifs
-
K. Kersse et al. The death-fold superfamily of homotypic interaction motifs Trends Biochem. Sci. 36 2011 541 552
-
(2011)
Trends Biochem. Sci.
, vol.36
, pp. 541-552
-
-
Kersse, K.1
-
21
-
-
33646941554
-
Role for erbin in bacterial activation of Nod2
-
T.A. Kufer et al. Role for erbin in bacterial activation of Nod2 Infect. Immun. 74 2006 3115 3124
-
(2006)
Infect. Immun.
, vol.74
, pp. 3115-3124
-
-
Kufer, T.A.1
-
22
-
-
84859056327
-
The tandem CARDs of NOD2: Intramolecular interactions and recognition of RIP2
-
V. Fridh, and K. Rittinger The tandem CARDs of NOD2: intramolecular interactions and recognition of RIP2 PLoS ONE 7 2012 e34375
-
(2012)
PLoS ONE
, vol.7
, pp. 34375
-
-
Fridh, V.1
Rittinger, K.2
-
23
-
-
28844475180
-
Gateway vectors for the production of combinatorially-tagged His6-MBP fusion proteins in the cytoplasm and periplasm of Escherichia coli
-
S. Nallamsetty et al. Gateway vectors for the production of combinatorially-tagged His6-MBP fusion proteins in the cytoplasm and periplasm of Escherichia coli Protein Sci. 14 2005 2964 2971
-
(2005)
Protein Sci.
, vol.14
, pp. 2964-2971
-
-
Nallamsetty, S.1
-
24
-
-
63849246525
-
Protein structure prediction on the Web: A case study using the Phyre server
-
L.A. Kelley, and M.J.E. Sternberg Protein structure prediction on the Web: a case study using the Phyre server Nat. Protoc. 4 2009 363 371
-
(2009)
Nat. Protoc.
, vol.4
, pp. 363-371
-
-
Kelley, L.A.1
Sternberg, M.J.E.2
-
25
-
-
84880280093
-
Crystal structure of NLRC4 reveals its autoinhibition mechanism
-
Z. Hu et al. Crystal structure of NLRC4 reveals its autoinhibition mechanism Science 341 2013 172 175
-
(2013)
Science
, vol.341
, pp. 172-175
-
-
Hu, Z.1
-
26
-
-
84864570457
-
Structural insights into the assembly of CARMA1 and BCL10
-
S. Li et al. Structural insights into the assembly of CARMA1 and BCL10 PLoS ONE 7 2012 e42775
-
(2012)
PLoS ONE
, vol.7
, pp. 42775
-
-
Li, S.1
-
27
-
-
80054078476
-
Fast, scalable generation of high-quality protein multiple sequence alignments using Clustal Omega
-
F. Sievers et al. Fast, scalable generation of high-quality protein multiple sequence alignments using Clustal Omega Mol. Syst. Biol. 7 2011 539
-
(2011)
Mol. Syst. Biol.
, vol.7
, pp. 539
-
-
Sievers, F.1
-
28
-
-
0037075551
-
RICK/Rip2/CARDIAK mediates signalling for receptors of the innate and adaptive immune systems
-
K. Kobayashi et al. RICK/Rip2/CARDIAK mediates signalling for receptors of the innate and adaptive immune systems Nature 416 2002 194 199
-
(2002)
Nature
, vol.416
, pp. 194-199
-
-
Kobayashi, K.1
-
29
-
-
0036671894
-
The inflammasome: A molecular platform triggering activation of inflammatory caspases and processing of proIL-beta
-
F. Martinon et al. The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta Mol. Cell 10 2002 417 426
-
(2002)
Mol. Cell
, vol.10
, pp. 417-426
-
-
Martinon, F.1
-
30
-
-
3242813113
-
The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses
-
M. Yoneyama et al. The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses Nat. Immunol. 5 2004 730 737
-
(2004)
Nat. Immunol.
, vol.5
, pp. 730-737
-
-
Yoneyama, M.1
-
31
-
-
84878523947
-
Caspase recruitment domain-containing protein 9 signaling in innate immunity and inflammation
-
S. Roth, and J. Ruland Caspase recruitment domain-containing protein 9 signaling in innate immunity and inflammation Trends Immunol. 34 2013 243 250
-
(2013)
Trends Immunol.
, vol.34
, pp. 243-250
-
-
Roth, S.1
Ruland, J.2
-
32
-
-
0034731443
-
CARD9 is a novel caspase recruitment domain-containing protein that interacts with BCL10/CLAP and activates NF-kappa B
-
J. Bertin et al. CARD9 is a novel caspase recruitment domain-containing protein that interacts with BCL10/CLAP and activates NF-kappa B J. Biol. Chem. 275 2000 41082 41086
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 41082-41086
-
-
Bertin, J.1
-
33
-
-
0036201577
-
CARD15/NOD2 mutational analysis and genotype-phenotype correlation in 612 patients with inflammatory bowel disease
-
S. Lesage et al. CARD15/NOD2 mutational analysis and genotype-phenotype correlation in 612 patients with inflammatory bowel disease Am. J. Hum. Genet. 70 2002 845 857
-
(2002)
Am. J. Hum. Genet.
, vol.70
, pp. 845-857
-
-
Lesage, S.1
-
34
-
-
1842592102
-
Crohn disease: Frequency and nature of CARD15 mutations in Ashkenazi and Sephardi/Oriental Jewish families
-
T. Tukel et al. Crohn disease: frequency and nature of CARD15 mutations in Ashkenazi and Sephardi/Oriental Jewish families Am. J. Hum. Genet. 74 2004 623 636
-
(2004)
Am. J. Hum. Genet.
, vol.74
, pp. 623-636
-
-
Tukel, T.1
-
35
-
-
39649109686
-
Novel CARD15/NOD2 mutations in Finnish patients with Crohn's disease and their relation to phenotypic variation in vitro and in vivo
-
M. Lappalainen et al. Novel CARD15/NOD2 mutations in Finnish patients with Crohn's disease and their relation to phenotypic variation in vitro and in vivo Inflamm. Bowel Dis. 14 2008 176 185
-
(2008)
Inflamm. Bowel Dis.
, vol.14
, pp. 176-185
-
-
Lappalainen, M.1
-
36
-
-
33645457756
-
Eight novel CARD15 variants detected by DNA sequence analysis of the CARD15 gene in 111 patients with inflammatory bowel disease
-
F. Schnitzler et al. Eight novel CARD15 variants detected by DNA sequence analysis of the CARD15 gene in 111 patients with inflammatory bowel disease Immunogenetics 58 2006 99 106
-
(2006)
Immunogenetics
, vol.58
, pp. 99-106
-
-
Schnitzler, F.1
-
37
-
-
17944372335
-
CARD15 mutations in Blau syndrome
-
C. Miceli-Richard et al. CARD15 mutations in Blau syndrome Nat. Genet. 29 2001 19 20
-
(2001)
Nat. Genet.
, vol.29
, pp. 19-20
-
-
Miceli-Richard, C.1
-
38
-
-
2342583513
-
Regulatory regions and critical residues of NOD2 involved in muramyl dipeptide recognition
-
T. Tanabe et al. Regulatory regions and critical residues of NOD2 involved in muramyl dipeptide recognition EMBO J. 23 2004 1587 1597
-
(2004)
EMBO J.
, vol.23
, pp. 1587-1597
-
-
Tanabe, T.1
|