Upregulation of adenylate cyclase 3 (ADCY3) increases the tumorigenic potential of cells by activating the CREB pathway

Oncotarget

Volumn 4, Issue 10, 2013, Pages 1791-1803

  Hong, Seung Hyun ^a   Goh, Sung Ho ^a   Lee, Sang Jin ^a   Hwang, Jung Ah ^a   Lee, Jieun ^a   Choi, Il Ju ^a   Seo, Hyehyun ^a   Park, Jong Hoon ^b   Suzuki, Hiromu ^c   Yamamoto, Eiichiro ^c   Kim, In Hoo ^a   Jeong, Jin Sook ^d   Ju, Mi Ha ^d   Lee, Dong Hee ^e   Lee, Yeon Su ^a  

^a National Cancer Center   (South Korea)

^b Sookmyung Women's University   (South Korea)

^c SAPPORO MEDICAL UNIVERSITY   (Japan)

^d Dong A University College of Medicine   (South Korea)

^e Ewha Womans University   (South Korea)

Author keywords

Adenylate cyclase; cAMP PKA CREB pathway; Gastric cancer; Promoter methylation; Tumorigenesis

Indexed keywords

CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; GELATINASE A; GELATINASE B; MESSENGER RNA;

ADENYLATE CYCLASE 3 GENE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL INVASION; CELL MIGRATION; CELL PROLIFERATION; CELL STRAIN HEK293; CONTROLLED STUDY; DNA METHYLATION; ENZYME ACTIVITY; EPIGENETICS; GENE; GENE EXPRESSION; HUMAN; HUMAN CELL; HUMAN TISSUE; MMP 2 GENE; MMP 9 GENE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PHENOTYPE; PROMOTER REGION; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; STOMACH CANCER; STOMACH CARCINOGENESIS; TUMOR PROMOTION; UPREGULATION;

ADENYLATE CYCLASE; ANIMALS; CELL GROWTH PROCESSES; CELL LINE, TUMOR; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; DNA METHYLATION; EPIGENESIS, GENETIC; GENE EXPRESSION REGULATION, NEOPLASTIC; HEK293 CELLS; HUMANS; IMMUNOHISTOCHEMISTRY; MICE; MICE, INBRED BALB C; MICE, NUDE; NEOPLASMS; RNA, MESSENGER; SIGNAL TRANSDUCTION; TRANSFECTION; UP-REGULATION; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84886734590     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.1324     Document Type: Article

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