Next generation exome sequencing of paediatric inflammatory bowel disease patients identifies rare and novel variants in candidate genes

Gut

Volumn 62, Issue 7, 2013, Pages 977-984

  Christodoulou, Katja ^a   Wiskin, Anthony E ^b   Gibson, Jane ^a   Tapper, William ^a   Willis, Claire ^b   Afzal, Nadeem A ^b   Upstill Goddard, Rosanna ^a   Holloway, John W ^c   Simpson, Michael A ^d   Beattie, R Mark ^b   Collins, Andrew ^a   Ennis, Sarah ^a  

^a UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

^b SOUTHAMPTON GENERAL HOSPITAL   (United Kingdom)

^c UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

^d GUY S HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE RECRUITMENT DOMAIN PROTEIN 15; DNA; HLA ANTIGEN; INTERLEUKIN 10; TOLL LIKE RECEPTOR ADAPTOR MOLECULE 1;

ARTICLE; BACH2 GENE; BTNL2 GENE; CONTROLLED STUDY; CROHN DISEASE; ENTERITIS; ERAP2 GENE; EXOME SEQUENCING; FEMALE; FRAMESHIFT MUTATION; GENE; GENE FREQUENCY; GENE FUNCTION; GENE IDENTIFICATION; GENE LOCATION; GENETIC ASSOCIATION; GENETIC VARIABILITY; GSDMB GENE; HLA GENE; HUMAN; ICAM1 GENE; IL1RL2 GENE; INTERLEUKIN 10 GENE; MAJOR CLINICAL STUDY; MALE; MOLECULAR DYNAMICS; NOD2 GENE; OUTCOME ASSESSMENT; PREDICTION; PRIORITY JOURNAL; SEC16A GENE; SEQUENCE ALIGNMENT; SEQUENCE ANALYSIS; SH2B1 GENE; SNAPC4 GENE; ULCERATIVE COLITIS;

CROHN'S DISEASE; IBD-GENETICS; INFLAMMATORY BOWEL DISEASE; PAEDIATRIC GASTROENTEROLOGY; ULCERATIVE COLITIS; ZOLLINGER ELLISON SYNDROME,;

ADOLESCENT; AGE OF ONSET; CHILD; CHILD, PRESCHOOL; COHORT STUDIES; COLITIS, ULCERATIVE; COMPUTER SIMULATION; CROHN DISEASE; DNA MUTATIONAL ANALYSIS; EXOME; FEMALE; GENE FREQUENCY; GENETIC ASSOCIATION STUDIES; GENETIC PREDISPOSITION TO DISEASE; HUMANS; INFLAMMATORY BOWEL DISEASES; MALE; MODELS, GENETIC; MUTATION; NOD2 SIGNALING ADAPTOR PROTEIN; PHENOTYPE;

EID: 84878764878     PISSN: 00175749     EISSN: 14683288     Source Type: Journal    
DOI: 10.1136/gutjnl-2011-301833     Document Type: Article

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