Changes in novel haematological parameters following thermal injury: A prospective observational cohort study

Scientific Reports

Volumn 7, Issue 1, 2017, Pages

  Dinsdale, R J ^a,b   Devi, A ^a,b   Hampson, P ^a,b   Wearn, C M ^a,b,c   Bamford, A L ^a,c   Hazeldine, J ^b,d   Bishop, J ^d   Ahmed, S ^c   Watson, C ^c   Lord, J M ^a,b,d   Moiemen, N ^a,c   Harrison, P ^a,b  

^a Scar Free Foundation Birmingham Centre for Burns Research   (United Kingdom)

^b UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^c QUEEN ELIZABETH HOSPITAL   (United Kingdom)

^d Edgbaston   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADOLESCENT; ADULT; AGED; BLOOD; BURN; COMPLICATION; FEMALE; HUMAN; MALE; MIDDLE AGED; PLATELET COUNT; PROSPECTIVE STUDY; SEPSIS; THROMBOCYTOSIS; TIME FACTOR; VERY ELDERLY; YOUNG ADULT;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; BURNS; FEMALE; HUMANS; MALE; MIDDLE AGED; PLATELET COUNT; PROSPECTIVE STUDIES; SEPSIS; THROMBOCYTOSIS; TIME FACTORS; YOUNG ADULT;

EID: 85020728550     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/s41598-017-03222-w     Document Type: Article

References (32)

1. Brusselaers, N., Monstrey, S., Vogelaers, D., Hoste, E., Blot, S. Severe burn injury in Europe: A systematic review of the incidence, etiology, morbidity, mortality. Crit Care 14, R188, doi:10.1186/cc9300 (2010).
2. Jeschke, M. G., et al. Pathophysiologic Response to Burns in the Elderly. EBioMedicine 2, 1536-1548, doi:10.1016/j.ebiom.2015.07.040 (2015).
3. Jackson, P. C., et al. Revised estimates of mortality from the Birmingham Burn Centre, 2001-2010: A continuing analysis over 65 years. Ann Surg 259, 979-984, doi:10.1097/SLA.0b013e31829160ca (2014).
4. Mann, E. A., Baun, M. M., Meininger, J. C., Wade, C. E. Comparison of mortality associated with sepsis in the burn, trauma, general intensive care unit patient: A systematic review of the literature. Shock 37, 4-16, doi:10.1097/SHK.0b013e318237d6bf (2012).
5. Levy, M. M., et al. 2001 SCCM/ESICM/ACCP/ATS/SIS International Sepsis Definitions Conference. Intensive Care Med 29, 530-538, doi:10.1007/s00134-003-1662-x (2003).
6. Hampson, P., et al. Neutrophil Dysfunction, Immature Granulocytes, Cell-free DNA are Early Biomarkers of Sepsis in Burninjured Patients: A Prospective Observational Cohort Study. Ann Surg, doi:10.1097/SLA.0000000000001807 (2016).
7. Ha, S. O., et al. Fraction of immature granulocytes reflects severity but not mortality in sepsis. Scand J Clin Lab Invest 75, 36-43, doi:10.3109/00365513.2014.965736 (2015).
8. Mare, T. A., et al. The diagnostic and prognostic significance of monitoring blood levels of immature neutrophils in patients with systemic inflammation. Crit Care 19, 57, doi:10.1186/s13054-015-0778-z (2015).
9. Marck, R. E., Montagne, H. L., Tuinebreijer, W. E., Breederveld, R. S. Time course of thrombocytes in burn patients and its predictive value for outcome. Burns 39, 714-722, doi:10.1016/j.burns.2013.01.015 (2013).
10. Gouel-Cheron, A., et al. Early interleukin-6 and slope of monocyte human leukocyte antigen-DR: A powerful association to predict the development of sepsis after major trauma. PLoS One 7, e33095, doi:10.1371/journal.pone.0033095 (2012).
11. Briggs, C., Harrison, P., Machin, S. J. Continuing developments with the automated platelet count. Int J Lab Hematol 29, 77-91, doi:10.1111/j.1751-553X.2007.00909.x (2007).
12. Nierhaus, A., et al. Revisiting the white blood cell count: Immature granulocytes count as a diagnostic marker to discriminate between SIRS and sepsis-a prospective, observational study. BMC Immunol 14, 8, doi:10.1186/1471-2172-14-8 (2013).
13. Wada, A., Takagi, Y., Kono, M., Morikawa, T. Accuracy of a New Platelet Count System (PLT-F) Depends on the Staining Property of Its Reagents. PLoS One 10, e0141311, doi:10.1371/journal.pone.0141311 (2015).
14. Tanaka, Y., et al. Performance evaluation of platelet counting by novel fluorescent dye staining in the XN-series automated hematology analyzers. J Clin Lab Anal 28, 341-348, doi:10.1002/jcla.21691 (2014).
15. Hergt, K. Blood levels of thrombocytes in burned patients: Observations on their behavior in relation to the clinical condition of the patient. J Trauma 12, 599-607 (1972).
16. Housinger, T. A., Brinkerhoff, C., Warden, G. D. The relationship between platelet count, sepsis, survival in pediatric burn patients. Arch Surg 128, 65-66; discussion 66-67 (1993).
17. Siegenthaler, M., Spertini, O. Images in clinical medicine. Spurious platelet count. N Engl J Med 354, 1936, doi:10.1056/NEJMicm050107 (2006).
18. Lawrence, C., Atac, B. Hematologic changes in massive burn injury. Crit Care Med 20, 1284-1288 (1992).
19. Harrison, P., et al. An interlaboratory study of a candidate reference method for platelet counting. Am J Clin Pathol 115, 448-459, doi:10.1309/91PR-E4G6-XBAF-N8DY (2001).
20. Zini, G., et al. ICSH recommendations for identification, diagnostic value, quantitation of schistocytes. Int J Lab Hematol 34, 107-116, doi:10.1111/j.1751-553X.2011.01380.x (2012).
21. Lesesve, J. F., et al. Schistocytes in disseminated intravascular coagulation. Int J Lab Hematol 36, 439-443, doi:10.1111/ijlh.12168 (2014).
22. Lesesve, J. F., Salignac, S., Lecompte, T. Laboratory measurement of schistocytes. Int J Lab Hematol 29, 149-151, doi:10.1111/j.1751-553X.2006.00829.x (2007).
23. Bessman, J. D. Red blood cell fragmentation. Improved detection and identification of causes. Am J Clin Pathol 90, 268-273 (1988).
24. Kono, M., et al. Heme-related molecules induce rapid production of neutrophil extracellular traps. Transfusion 54, 2811-2819, doi:10.1111/trf.12700 (2014).
25. Chen, G., et al. Heme-induced neutrophil extracellular traps contribute to the pathogenesis of sickle cell disease. Blood 123, 3818-3827, doi:10.1182/blood-2013-10-529982 (2014).
26. Alexander, J. W., Ogle, C. K., Stinnett, J. D., Macmillan, B. G. A sequential, prospective analysis of immunologic abnormalities and infection following severe thermal injury. Ann Surg 188, 809-816 (1978).
27. Sheng, Z. Y., Tung, Y. L. Neutrophil chemiluminescence in burned patients. J Trauma 27, 587-595 (1987).
28. Jones, C. N., et al. Spontaneous neutrophil migration patterns during sepsis after major burns. PLoS One 9, e114509, doi:10.1371/journal.pone.0114509 (2014).
29. Luo, Y., et al. Utility of neut-X, neut-Y and neut-Z parameters for rapidly assessing sepsis in tumor patients. Clin Chim Acta 422, 5-9, doi:10.1016/j.cca.2013.03.026 (2013).
30. Stiel, L., et al. Neutrophil Fluorescence: A New Indicator of Cell Activation During Septic Shock-Induced Disseminated Intravascular Coagulation. Crit Care Med. doi:10.1097/CCM.0000000000001851 (2016).
31. Cornet, E., Boubaya, M., Troussard, X. Contribution of the new XN-1000 parameters NEUT-RI and NEUT-WY for managing patients with immature granulocytes. Int J Lab Hematol 37, e123-126, doi:10.1111/ijlh.12372 (2015).
32. Greenhalgh, D. G., et al. American Burn Association consensus conference to define sepsis and infection in burns. J Burn Care Res 28, 776-790, doi:10.1097/BCR.0b013e3181599bc9 (2007).