Neutrophil dysfunction, immature granulocytes, and cell-free DNA are early biomarkers of sepsis in burn-injured patients: A prospective observational cohort study

Annals of Surgery

Volumn 265, Issue 6, 2017, Pages 1241-1249

  Hampson, Peter ^a,b   Dinsdale, Robert J ^a,b   Wearn, Christopher M ^a,b   Bamford, Amy L ^a   Bishop, Jonathan R B ^c   Hazeldine, Jon ^b,c   Moiemen, Naiem S ^a   Harrison, Paul ^a,b   Lord, Janet M ^a,b,c  

^a Healing Foundation Burns Research Centre   (United Kingdom)

^b UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^c UNIVERSITY HOSPITALS BIRMINGHAM NHS FOUNDATION TRUST   (United Kingdom)

Author keywords

Burns; Cell free DNA; Immature granulocytes; NETs; Neutrophils; Sepsis

Indexed keywords

BIOLOGICAL MARKER; CELL FREE DNA; CELL NUCLEUS DNA; CYTOCHROME B; DNA; HEMOGLOBIN BETA CHAIN; HISTONE H3; MITOCHONDRIAL DNA; UNCLASSIFIED DRUG; HISTONE;

ADULT; ARTICLE; BLOOD CELL COUNT; BURN; BURN PATIENT; CELL PHAGOCYTOSIS; CELLULAR PARAMETERS; COHORT ANALYSIS; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIAGNOSTIC TEST ACCURACY STUDY; EARLY DIAGNOSIS; EXTRACELLULAR TRAP; FEMALE; GRANULOCYTE; HUMAN; HUMAN CELL; IMMATURE GRANULOCYTE COUNT; LEUKOCYTE FUNCTION; LONGITUDINAL STUDY; MAJOR CLINICAL STUDY; MALE; NEUTROPHIL; OBSERVATIONAL STUDY; PHAGOCYTIC INDEX; PREDICTIVE VALUE; PRIORITY JOURNAL; PROSPECTIVE STUDY; PROTEIN BLOOD LEVEL; RESPIRATORY BURST; SEPSIS; THERMAL INJURY; BLOOD; COMPLICATION; CROSS INFECTION; LEUKOCYTE COUNT; PHAGOCYTOSIS; PHYSIOLOGY;

BIOMARKERS; BURNS; CROSS INFECTION; DNA; GRANULOCYTES; HISTONES; HUMANS; LEUKOCYTE COUNT; NEUTROPHILS; PHAGOCYTOSIS; PROSPECTIVE STUDIES; RESPIRATORY BURST; SEPSIS;

EID: 84969930943     PISSN: 00034932     EISSN: 15281140     Source Type: Journal    
DOI: 10.1097/SLA.0000000000001807     Document Type: Article

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