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Volumn 74, Issue 6, 2017, Pages 718-726

Evaluation of amyloid protective factors and alzheimer disease neurodegeneration protective factors in elderly individuals

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID PROTEIN; APOLIPOPROTEIN E; 2-(4'-(METHYLAMINO)PHENYL)-6-HYDROXYBENZOTHIAZOLE; AMYLOID BETA PROTEIN; ANILINE DERIVATIVE; THIAZOLE DERIVATIVE;

EID: 85020695128     PISSN: 21686149     EISSN: None     Source Type: Journal    
DOI: 10.1001/jamaneurol.2017.0244     Document Type: Article
Times cited : (110)

References (67)
  • 1
    • 1842510004 scopus 로고    scopus 로고
    • Early Abeta accumulation and progressive synaptic loss, gliosis, and tangle formation in AD brain
    • Ingelsson M, Fukumoto H, Newell KL, et al. Early Abeta accumulation and progressive synaptic loss, gliosis, and tangle formation in AD brain. Neurology. 2004;62(6):925-931.
    • (2004) Neurology , vol.62 , Issue.6 , pp. 925-931
    • Ingelsson, M.1    Fukumoto, H.2    Newell, K.L.3
  • 2
    • 84872379077 scopus 로고    scopus 로고
    • Tracking pathophysiological processes in Alzheimer's disease: An updated hypothetical model of dynamic biomarkers
    • Jack CR Jr, Knopman DS, Jagust WJ, et al. Tracking pathophysiological processes in Alzheimer's disease: an updated hypothetical model of dynamic biomarkers. Lancet Neurol. 2013;12(2):207-216.
    • (2013) Lancet Neurol , vol.12 , Issue.2 , pp. 207-216
    • Jack, C.R.1    Knopman, D.S.2    Jagust, W.J.3
  • 3
    • 0029561222 scopus 로고
    • Apolipoprotein E (APOE) allele frequencies in late-onset sporadic Alzheimer's disease (AD), mixed dementia and vascular dementia: Lack of association of epsilon 4 allele with AD in Italian octogenarian patients
    • Scacchi R, De Bernardini L, Mantuano E, Donini LM, Vilardo T, Corbo RM. Apolipoprotein E (APOE) allele frequencies in late-onset sporadic Alzheimer's disease (AD), mixed dementia and vascular dementia: lack of association of epsilon 4 allele with AD in Italian octogenarian patients. Neurosci Lett. 1995;201(3):231-234.
    • (1995) Neurosci Lett. , vol.201 , Issue.3 , pp. 231-234
    • Scacchi, R.1    De Bernardini, L.2    Mantuano, E.3    Donini, L.M.4    Vilardo, T.5    Corbo, R.M.6
  • 4
    • 0029037609 scopus 로고
    • Lack of association of apolipoprotein E allele epsilon 4 with late-onset Alzheimer's disease among Finnish centenarians
    • Sobel E, Louhija J, Sulkava R, et al. Lack of association of apolipoprotein E allele epsilon 4 with late-onset Alzheimer's disease among Finnish centenarians. Neurology. 1995;45(5):903-907.
    • (1995) Neurology , vol.45 , Issue.5 , pp. 903-907
    • Sobel, E.1    Louhija, J.2    Sulkava, R.3
  • 5
    • 0030823158 scopus 로고    scopus 로고
    • Effects of age, sex, and ethnicity on the association between apolipoprotein E genotype and Alzheimer disease. A meta-analysis
    • Farrer LA, Cupples LA, Haines JL, et al; APOE and Alzheimer Disease Meta Analysis Consortium. Effects of age, sex, and ethnicity on the association between apolipoprotein E genotype and Alzheimer disease. a meta-analysis. JAMA. 1997;278(16):1349-1356.
    • (1997) JAMA , vol.278 , Issue.16 , pp. 1349-1356
    • Farrer, L.A.1    Cupples, L.A.2    Haines, J.L.3
  • 6
    • 79958116172 scopus 로고    scopus 로고
    • Alzheimer's disease is not "brain aging": Neuropathological, genetic, and epidemiological human studies
    • Nelson PT, Head E, Schmitt FA, et al. Alzheimer's disease is not "brain aging": neuropathological, genetic, and epidemiological human studies. Acta Neuropathol. 2011;121(5):571-587.
    • (2011) Acta Neuropathol , vol.121 , Issue.5 , pp. 571-587
    • Nelson, P.T.1    Head, E.2    Schmitt, F.A.3
  • 7
    • 84908009018 scopus 로고    scopus 로고
    • Age-specific population frequencies of cerebral β-amyloidosis and neurodegeneration among people with normal cognitive function aged 50-89 years: A cross-sectional study
    • Jack CR Jr, Wiste HJ, Weigand SD, et al. Age-specific population frequencies of cerebral β-amyloidosis and neurodegeneration among people with normal cognitive function aged 50-89 years: a cross-sectional study. Lancet Neurol. 2014;13(10):997-1005.
    • (2014) Lancet Neurol. , vol.13 , Issue.10 , pp. 997-1005
    • Jack, C.R.1    Wiste, H.J.2    Weigand, S.D.3
  • 8
    • 84946430861 scopus 로고    scopus 로고
    • The role of cerebrovascular disease when there is concomitant Alzheimer disease
    • Vemuri P, Knopman DS. The role of cerebrovascular disease when there is concomitant Alzheimer disease. Biochim Biophys Acta. 2015;1862(5):952-956.
    • (2015) Biochim Biophys Acta , vol.1862 , Issue.5 , pp. 952-956
    • Vemuri, P.1    Knopman, D.S.2
  • 9
    • 84937529452 scopus 로고    scopus 로고
    • Prevalence of cerebral amyloid pathology in persons without dementia: A meta-analysis
    • Jansen WJ, Ossenkoppele R, Knol DL, et al; Amyloid Biomarker Study Group. Prevalence of cerebral amyloid pathology in persons without dementia: a meta-analysis. JAMA. 2015;313(19):1924-1938.
    • (2015) JAMA , vol.313 , Issue.19 , pp. 1924-1938
    • Jansen, W.J.1    Ossenkoppele, R.2    Knol, D.L.3
  • 10
    • 84981225490 scopus 로고    scopus 로고
    • Age, sex, and APOE ε4 effects on memory, brain structure, and β-amyloid across the adult life span
    • Jack CR Jr, Wiste HJ, Weigand SD, et al. Age, sex, and APOE ε4 effects on memory, brain structure, and β-amyloid across the adult life span. JAMA Neurol. 2015;72(5):511-519.
    • (2015) JAMA Neurol. , vol.72 , Issue.5 , pp. 511-519
    • Jack, C.R.1    Wiste, H.J.2    Weigand, S.D.3
  • 12
    • 84905981347 scopus 로고    scopus 로고
    • Association of lifetime intellectual enrichment with cognitive decline in the older population
    • Vemuri P, Lesnick TG, Przybelski SA, et al. Association of lifetime intellectual enrichment with cognitive decline in the older population. JAMA Neurol. 2014;71(8):1017-1024.
    • (2014) JAMA Neurol. , vol.71 , Issue.8 , pp. 1017-1024
    • Vemuri, P.1    Lesnick, T.G.2    Przybelski, S.A.3
  • 13
    • 0035479310 scopus 로고    scopus 로고
    • Diabetes mellitus and risk of Alzheimer's disease and dementia with stroke in a multiethnic cohort
    • Luchsinger JA, Tang M-X, Stern Y, Shea S, Mayeux R. Diabetes mellitus and risk of Alzheimer's disease and dementia with stroke in a multiethnic cohort. Am J Epidemiol. 2001;154(7):635-641.
    • (2001) Am J Epidemiol , vol.154 , Issue.7 , pp. 635-641
    • Luchsinger, J.A.1    Tang, M.-X.2    Stern, Y.3    Shea, S.4    Mayeux, R.5
  • 14
    • 62449142597 scopus 로고    scopus 로고
    • The role of metabolic disorders in Alzheimer disease and vascular dementia: Two roads converged
    • Craft S. The role of metabolic disorders in Alzheimer disease and vascular dementia: two roads converged. Arch Neurol. 2009;66(3):300-305.
    • (2009) Arch Neurol , vol.66 , Issue.3 , pp. 300-305
    • Craft, S.1
  • 15
    • 26444463825 scopus 로고    scopus 로고
    • Obesity and vascular risk factors at midlife and the risk of dementia and Alzheimer disease
    • Kivipelto M, Ngandu T, Fratiglioni L, et al. Obesity and vascular risk factors at midlife and the risk of dementia and Alzheimer disease. Arch Neurol. 2005;62(10):1556-1560.
    • (2005) Arch Neurol , vol.62 , Issue.10 , pp. 1556-1560
    • Kivipelto, M.1    Ngandu, T.2    Fratiglioni, L.3
  • 16
    • 84928905831 scopus 로고    scopus 로고
    • Smoking is associated with an increased risk of dementia: A meta-analysis of prospective cohort studies with investigation of potential effect modifiers
    • Zhong G, Wang Y, Zhang Y, Guo JJ, Zhao Y. Smoking is associated with an increased risk of dementia: a meta-analysis of prospective cohort studies with investigation of potential effect modifiers. PLoS One. 2015;10(3):e0118333.
    • (2015) PLoS One , vol.10 , Issue.3
    • Zhong, G.1    Wang, Y.2    Zhang, Y.3    Guo, J.J.4    Zhao, Y.5
  • 17
    • 84882801362 scopus 로고    scopus 로고
    • Vascular risk factors and neurodegeneration in ageing related dementias: Alzheimer's disease and vascular dementia
    • Akinyemi RO, Mukaetova-Ladinska EB, Attems J, Ihara M, Kalaria RN. Vascular risk factors and neurodegeneration in ageing related dementias: Alzheimer's disease and vascular dementia. Curr Alzheimer Res. 2013;10(6):642-653.
    • (2013) Curr Alzheimer Res , vol.10 , Issue.6 , pp. 642-653
    • Akinyemi, R.O.1    Mukaetova-Ladinska, E.B.2    Attems, J.3    Ihara, M.4    Kalaria, R.N.5
  • 18
    • 18844445577 scopus 로고    scopus 로고
    • Risk factors for progression of brain atrophy in aging: Six-year follow-up of normal subjects
    • Enzinger C, Fazekas F, Matthews PM, et al. Risk factors for progression of brain atrophy in aging: six-year follow-up of normal subjects. Neurology. 2005;64(10):1704-1711.
    • (2005) Neurology , vol.64 , Issue.10 , pp. 1704-1711
    • Enzinger, C.1    Fazekas, F.2    Matthews, P.M.3
  • 19
    • 84901299033 scopus 로고    scopus 로고
    • Diabetes and elevated hemoglobin A1c levels are associated with brain hypometabolism but not amyloid accumulation
    • Roberts RO, Knopman DS, Cha RH, et al. Diabetes and elevated hemoglobin A1c levels are associated with brain hypometabolism but not amyloid accumulation. J Nucl Med. 2014;55(5):759-764.
    • (2014) J Nucl Med , vol.55 , Issue.5 , pp. 759-764
    • Roberts, R.O.1    Knopman, D.S.2    Cha, R.H.3
  • 20
    • 84942193148 scopus 로고    scopus 로고
    • Multimorbidity and risk of mild cognitive impairment
    • Vassilaki M, Aakre JA, Cha RH, et al. Multimorbidity and risk of mild cognitive impairment. J Am Geriatr Soc. 2015;63(9):1783-1790.
    • (2015) J Am Geriatr Soc , vol.63 , Issue.9 , pp. 1783-1790
    • Vassilaki, M.1    Aakre, J.A.2    Cha, R.H.3
  • 21
    • 84973532372 scopus 로고    scopus 로고
    • Multimorbidity and neuroimaging biomarkers among cognitively normal persons
    • Vassilaki M, Aakre JA, Mielke MM, et al. Multimorbidity and neuroimaging biomarkers among cognitively normal persons. Neurology. 2016;86(22):2077-2084.
    • (2016) Neurology , vol.86 , Issue.22 , pp. 2077-2084
    • Vassilaki, M.1    Aakre, J.A.2    Mielke, M.M.3
  • 22
    • 84872916071 scopus 로고    scopus 로고
    • History of the Rochester Epidemiology Project: Half a century of medical records linkage in a US population
    • Rocca WA, Yawn BP, St Sauver JL, Grossardt BR, Melton LJ III. History of the Rochester Epidemiology Project: half a century of medical records linkage in a US population. Mayo Clin Proc. 2012;87(12):1202-1213.
    • (2012) Mayo Clin Proc , vol.87 , Issue.12 , pp. 1202-1213
    • Rocca, W.A.1    Yawn, B.P.2    St Sauver, J.L.3    Grossardt, B.R.4    Melton, L.J.5
  • 23
    • 84856657579 scopus 로고    scopus 로고
    • Generalizability of epidemiological findings and public health decisions: An illustration from the Rochester Epidemiology Project
    • St Sauver JL, Grossardt BR, Leibson CL, Yawn BP, Melton LJ III, Rocca WA. Generalizability of epidemiological findings and public health decisions: an illustration from the Rochester Epidemiology Project. Mayo Clin Proc. 2012;87(2):151-160.
    • (2012) Mayo Clin Proc , vol.87 , Issue.2 , pp. 151-160
    • St Sauver, J.L.1    Grossardt, B.R.2    Leibson, C.L.3    Yawn, B.P.4    Melton, L.J.5    Rocca, W.A.6
  • 24
    • 84872139404 scopus 로고    scopus 로고
    • Data resource profile: The Rochester Epidemiology Project (REP) medical records-linkage system
    • St Sauver JL, Grossardt BR, Yawn BP, et al. Data resource profile: the Rochester Epidemiology Project (REP) medical records-linkage system. Int J Epidemiol. 2012;41(6):1614-1624.
    • (2012) Int J Epidemiol , vol.41 , Issue.6 , pp. 1614-1624
    • St Sauver, J.L.1    Grossardt, B.R.2    Yawn, B.P.3
  • 25
    • 79955633775 scopus 로고    scopus 로고
    • Use of a medical records linkage system to enumerate a dynamic population over time: The Rochester epidemiology project
    • St Sauver JL, Grossardt BR, Yawn BP, Melton LJ III, Rocca WA. Use of a medical records linkage system to enumerate a dynamic population over time: the Rochester epidemiology project. Am J Epidemiol. 2011;173(9):1059-1068.
    • (2011) Am J Epidemiol , vol.173 , Issue.9 , pp. 1059-1068
    • St Sauver, J.L.1    Grossardt, B.R.2    Yawn, B.P.3    Melton, L.J.4    Rocca, W.A.5
  • 26
    • 77957057877 scopus 로고    scopus 로고
    • The Mayo Clinic Study of Aging. Prevalence of mild cognitive impairment is higher in men
    • Petersen RC, Roberts RO, Knopman DS, et al; The Mayo Clinic Study of Aging. Prevalence of mild cognitive impairment is higher in men. Neurology. 2010;75(10):889-897.
    • (2010) Neurology , vol.75 , Issue.10 , pp. 889-897
    • Petersen, R.C.1    Roberts, R.O.2    Knopman, D.S.3
  • 27
    • 84858019144 scopus 로고    scopus 로고
    • The incidence of MCI differs by subtype and is higher in men: The Mayo Clinic Study of Aging
    • Roberts RO, Geda YE, Knopman DS, et al. The incidence of MCI differs by subtype and is higher in men: the Mayo Clinic Study of Aging. Neurology. 2012;78(5):342-351.
    • (2012) Neurology , vol.78 , Issue.5 , pp. 342-351
    • Roberts, R.O.1    Geda, Y.E.2    Knopman, D.S.3
  • 28
    • 84871972979 scopus 로고    scopus 로고
    • Effect of lifestyle activities on Alzheimer disease biomarkers and cognition
    • Vemuri P, Lesnick TG, Przybelski SA, et al. Effect of lifestyle activities on Alzheimer disease biomarkers and cognition. Ann Neurol. 2012;72(5):730-738.
    • (2012) Ann Neurol , vol.72 , Issue.5 , pp. 730-738
    • Vemuri, P.1    Lesnick, T.G.2    Przybelski, S.A.3
  • 29
    • 85047689465 scopus 로고    scopus 로고
    • Engaging in cognitive activities, aging, and mild cognitive impairment: A population-based study
    • Geda YE, Topazian HM, Roberts LA, et al. Engaging in cognitive activities, aging, and mild cognitive impairment: a population-based study. J Neuropsychiatry Clin Neurosci. 2011;23(2):149-154.
    • (2011) J Neuropsychiatry Clin Neurosci , vol.23 , Issue.2 , pp. 149-154
    • Geda, Y.E.1    Topazian, H.M.2    Roberts, L.A.3
  • 30
    • 84898713190 scopus 로고    scopus 로고
    • Association of type 2 diabetes with brain atrophy and cognitive impairment
    • Roberts RO, Knopman DS, Przybelski SA, et al. Association of type 2 diabetes with brain atrophy and cognitive impairment. Neurology. 2014;82(13):1132-1141.
    • (2014) Neurology , vol.82 , Issue.13 , pp. 1132-1141
    • Roberts, R.O.1    Knopman, D.S.2    Przybelski, S.A.3
  • 31
    • 66649137729 scopus 로고    scopus 로고
    • Comparison of 18F-FDG and PiB PET in cognitive impairment
    • Lowe VJ, Kemp BJ, Jack CR Jr, et al. Comparison of 18F-FDG and PiB PET in cognitive impairment. J Nucl Med. 2009;50(6):878-886.
    • (2009) J Nucl Med , vol.50 , Issue.6 , pp. 878-886
    • Lowe, V.J.1    Kemp, B.J.2    Jack, C.R.3
  • 32
    • 39749108812 scopus 로고    scopus 로고
    • 11C PiB and structural MRI provide complementary information in imaging of Alzheimer's disease and amnestic mild cognitive impairment
    • Jack CR Jr, Lowe VJ, Senjem ML, et al. 11C PiB and structural MRI provide complementary information in imaging of Alzheimer's disease and amnestic mild cognitive impairment. Brain. 2008;131(Pt 3):665-680.
    • (2008) Brain , vol.131 , pp. 665-680
    • Jack, C.R.1    Lowe, V.J.2    Senjem, M.L.3
  • 33
    • 84871954000 scopus 로고    scopus 로고
    • Automated ROI analysis of 11C Pittsburgh compound B images using structural magnetic resonance imaging atlases, Alzheimer's and Dementia
    • Senjem ML, Lowe V, Kemp B, et al. Automated ROI analysis of 11C Pittsburgh compound B images using structural magnetic resonance imaging atlases, Alzheimer's and Dementia. Paper presented at the 2008 Alzheimer's Association International Conference on Alzheimer's Disease.
    • 2008 Alzheimer's Association International Conference on Alzheimer's Disease
    • Senjem, M.L.1    Lowe, V.2    Kemp, B.3
  • 34
    • 33644876596 scopus 로고    scopus 로고
    • Simplified quantification of Pittsburgh Compound B amyloid imaging PET studies: A comparative analysis
    • Lopresti BJ, Klunk WE, Mathis CA, et al. Simplified quantification of Pittsburgh Compound B amyloid imaging PET studies: a comparative analysis. J Nucl Med. 2005;46(12):1959-1972.
    • (2005) J Nucl Med , vol.46 , Issue.12 , pp. 1959-1972
    • Lopresti, B.J.1    Klunk, W.E.2    Mathis, C.A.3
  • 35
    • 84951033618 scopus 로고    scopus 로고
    • Different definitions of neurodegeneration produce similar amyloid/neurodegeneration biomarker group findings
    • Jack CR Jr, Wiste HJ, Weigand SD, et al. Different definitions of neurodegeneration produce similar amyloid/neurodegeneration biomarker group findings. Brain. 2015;138(Pt 12):3747-3759.
    • (2015) Brain , vol.138 , pp. 3747-3759
    • Jack, C.R.1    Wiste, H.J.2    Weigand, S.D.3
  • 36
    • 84875250937 scopus 로고    scopus 로고
    • Amyloid β deposition, neurodegeneration, and cognitive decline in sporadic Alzheimer's disease: A prospective cohort study
    • Villemagne VL, Burnham S, Bourgeat P, et al; Australian Imaging Biomarkers and Lifestyle (AIBL) Research Group. Amyloid β deposition, neurodegeneration, and cognitive decline in sporadic Alzheimer's disease: a prospective cohort study. Lancet Neurol. 2013;12(4):357-367.
    • (2013) Lancet Neurol , vol.12 , Issue.4 , pp. 357-367
    • Villemagne, V.L.1    Burnham, S.2    Bourgeat, P.3
  • 37
    • 79955768543 scopus 로고    scopus 로고
    • Longitudinal patterns of β-amyloid deposition in nondemented older adults
    • Sojkova J, Zhou Y, An Y, et al. Longitudinal patterns of β-amyloid deposition in nondemented older adults. Arch Neurol. 2011;68(5):644-649.
    • (2011) Arch Neurol , vol.68 , Issue.5 , pp. 644-649
    • Sojkova, J.1    Zhou, Y.2    An, Y.3
  • 38
    • 3242682466 scopus 로고    scopus 로고
    • The biphasic relationship between regional brain senile plaque and neurofibrillary tangle distributions: Modification by age, sex, and APOE polymorphism
    • Corder EH, Ghebremedhin E, Taylor MG, Thal DR, Ohm TG, Braak H. The biphasic relationship between regional brain senile plaque and neurofibrillary tangle distributions: modification by age, sex, and APOE polymorphism. Ann N Y Acad Sci. 2004;1019:24-28.
    • (2004) Ann N Y Acad Sci , vol.1019 , pp. 24-28
    • Corder, E.H.1    Ghebremedhin, E.2    Taylor, M.G.3    Thal, D.R.4    Ohm, T.G.5    Braak, H.6
  • 39
    • 84892174473 scopus 로고    scopus 로고
    • Clinical epidemiology of Alzheimer's disease: Assessing sex and gender differences
    • Mielke MM, Vemuri P, Rocca WA. Clinical epidemiology of Alzheimer's disease: assessing sex and gender differences. Clin Epidemiol. 2014;6:37-48.
    • (2014) Clin Epidemiol , vol.6 , pp. 37-48
    • Mielke, M.M.1    Vemuri, P.2    Rocca, W.A.3
  • 40
    • 0001504829 scopus 로고    scopus 로고
    • Simvastatin strongly reduces levels of Alzheimer's disease beta-amyloid peptides Abeta 42 and Abeta 40 in vitro and in vivo
    • Fassbender K, Simons M, Bergmann C, et al. Simvastatin strongly reduces levels of Alzheimer's disease beta-amyloid peptides Abeta 42 and Abeta 40 in vitro and in vivo. Proc Natl Acad Sci U S A. 2001;98(10):5856-5861.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , Issue.10 , pp. 5856-5861
    • Fassbender, K.1    Simons, M.2    Bergmann, C.3
  • 42
    • 84863006444 scopus 로고    scopus 로고
    • Dyslipidemia and dementia: Current epidemiology, genetic evidence, and mechanisms behind the associations
    • Reitz C. Dyslipidemia and dementia: current epidemiology, genetic evidence, and mechanisms behind the associations. J Alzheimers Dis. 2012;30(suppl 2):S127-S145.
    • (2012) J Alzheimers Dis , vol.30 , pp. S127-S145
    • Reitz, C.1
  • 43
    • 0037031125 scopus 로고    scopus 로고
    • Apolipoprotein E epsilon4 allele, elevated midlife total cholesterol level, and high midlife systolic blood pressure are independent risk factors for late-life Alzheimer disease
    • Kivipelto M, Helkala EL, Laakso MP, et al. Apolipoprotein E epsilon4 allele, elevated midlife total cholesterol level, and high midlife systolic blood pressure are independent risk factors for late-life Alzheimer disease. Ann Intern Med. 2002;137(3):149-155.
    • (2002) Ann Intern Med , vol.137 , Issue.3 , pp. 149-155
    • Kivipelto, M.1    Helkala, E.L.2    Laakso, M.P.3
  • 44
    • 84929295476 scopus 로고    scopus 로고
    • Insulin resistance predicts brain amyloid deposition in late middle-aged adults
    • Willette AA, Johnson SC, Birdsill AC, et al. Insulin resistance predicts brain amyloid deposition in late middle-aged adults. Alzheimers Dement. 2015;11(5):504-510.e1, e1.
    • (2015) Alzheimers Dement , vol.11 , Issue.5
    • Willette, A.A.1    Johnson, S.C.2    Birdsill, A.C.3
  • 45
    • 84883824146 scopus 로고    scopus 로고
    • Glucose intolerance, insulin resistance, and pathological features of Alzheimer disease in the Baltimore Longitudinal Study of Aging
    • Thambisetty M, Jeffrey Metter E, Yang A, et al. Glucose intolerance, insulin resistance, and pathological features of Alzheimer disease in the Baltimore Longitudinal Study of Aging. JAMA Neurol. 2013;70(9):1167-1172.
    • (2013) JAMA Neurol , vol.70 , Issue.9 , pp. 1167-1172
    • Thambisetty, M.1    Jeffrey Metter, E.2    Yang, A.3
  • 46
    • 84900485727 scopus 로고    scopus 로고
    • What is normal in normal aging? Effects of aging, amyloid and Alzheimer's disease on the cerebral cortex and the hippocampus
    • Alzheimer's Disease Neuroimaging Initiative
    • Fjell AM, McEvoy L, Holland D, Dale AM, Walhovd KB; Alzheimer's Disease Neuroimaging Initiative. What is normal in normal aging? effects of aging, amyloid and Alzheimer's disease on the cerebral cortex and the hippocampus. Prog Neurobiol. 2014;117:20-40.
    • (2014) Prog Neurobiol , vol.117 , pp. 20-40
    • Fjell, A.M.1    McEvoy, L.2    Holland, D.3    Dale, A.M.4    Walhovd, K.B.5
  • 47
    • 77649314191 scopus 로고    scopus 로고
    • APOE predicts amyloid-beta but not tau Alzheimer pathology in cognitively normal aging
    • Morris JC, Roe CM, Xiong C, et al. APOE predicts amyloid-beta but not tau Alzheimer pathology in cognitively normal aging. Ann Neurol. 2010;67(1):122-131.
    • (2010) Ann Neurol , vol.67 , Issue.1 , pp. 122-131
    • Morris, J.C.1    Roe, C.M.2    Xiong, C.3
  • 48
    • 77950545456 scopus 로고    scopus 로고
    • Effect of apolipoprotein E on biomarkers of amyloid load and neuronal pathology in Alzheimer disease
    • Alzheimer's Disease Neuroimaging Initiative
    • Vemuri P, Wiste HJ, Weigand SD, et al; Alzheimer's Disease Neuroimaging Initiative. Effect of apolipoprotein E on biomarkers of amyloid load and neuronal pathology in Alzheimer disease. Ann Neurol. 2010;67(3):308-316.
    • (2010) Ann Neurol , vol.67 , Issue.3 , pp. 308-316
    • Vemuri, P.1    Wiste, H.J.2    Weigand, S.D.3
  • 49
    • 0025863618 scopus 로고
    • Neuropathological stageing of Alzheimer-related changes
    • Braak H, Braak E. Neuropathological stageing of Alzheimer-related changes. Acta Neuropathol. 1991;82(4):239-259.
    • (1991) Acta Neuropathol , vol.82 , Issue.4 , pp. 239-259
    • Braak, H.1    Braak, E.2
  • 50
    • 84862767786 scopus 로고    scopus 로고
    • An operational approach to NIA-AA criteria for preclinical Alzheimer's disease
    • Jack CR Jr, Knopman DS, Weigand SD, et al. An operational approach to NIA-AA criteria for preclinical Alzheimer's disease. Ann Neurol. 2012;71(6):765-775.
    • (2012) Ann Neurol , vol.71 , Issue.6 , pp. 765-775
    • Jack, C.R.1    Knopman, D.S.2    Weigand, S.D.3
  • 51
    • 84878407796 scopus 로고    scopus 로고
    • Brain injury biomarkers are not dependent on β-amyloid in normal elderly
    • Knopman DS, Jack CR Jr, Wiste HJ, et al. Brain injury biomarkers are not dependent on β-amyloid in normal elderly. Ann Neurol. 2013;73(4):472-480.
    • (2013) Ann Neurol , vol.73 , Issue.4 , pp. 472-480
    • Knopman, D.S.1    Jack, C.R.2    Wiste, H.J.3
  • 52
    • 84961659530 scopus 로고    scopus 로고
    • Effect of intellectual enrichment on AD biomarker trajectories: Longitudinal imaging study
    • Vemuri P, Lesnick TG, Przybelski SA, et al. Effect of intellectual enrichment on AD biomarker trajectories: longitudinal imaging study. Neurology. 2016;86(12):1128-1135.
    • (2016) Neurology , vol.86 , Issue.12 , pp. 1128-1135
    • Vemuri, P.1    Lesnick, T.G.2    Przybelski, S.A.3
  • 53
    • 70349140909 scopus 로고    scopus 로고
    • Lifespan profiles of Alzheimer's disease-associated genes and products in monkeys and mice
    • Dosunmu R, Wu J, Adwan L, et al. Lifespan profiles of Alzheimer's disease-associated genes and products in monkeys and mice. J Alzheimers Dis. 2009;18(1):211-230.
    • (2009) J Alzheimers Dis , vol.18 , Issue.1 , pp. 211-230
    • Dosunmu, R.1    Wu, J.2    Adwan, L.3
  • 54
    • 79960437579 scopus 로고    scopus 로고
    • Genetic profiles of longevity and healthy cognitive aging in nonagenarians from the Basque Country
    • Elcoroaristizabal Martín X, Gómez Busto F, Artaza Artabe I, et al. Genetic profiles of longevity and healthy cognitive aging in nonagenarians from the Basque Country. Rev Esp Geriatr Gerontol. 2011;46(4):217-222.
    • (2011) Rev Esp Geriatr Gerontol , vol.46 , Issue.4 , pp. 217-222
    • Elcoroaristizabal Martín, X.1    Gómez Busto, F.2    Artaza Artabe, I.3
  • 55
    • 84886793791 scopus 로고    scopus 로고
    • Meta-analysis of genetic variants associated with human exceptional longevity
    • Sebastiani P, Bae H, Sun FX, et al. Meta-analysis of genetic variants associated with human exceptional longevity. Aging (Albany NY). 2013;5(9):653-661.
    • (2013) Aging (Albany NY) , vol.5 , Issue.9 , pp. 653-661
    • Sebastiani, P.1    Bae, H.2    Sun, F.X.3
  • 56
    • 84889653145 scopus 로고    scopus 로고
    • The forgotten APOE allele: A review of the evidence and suggested mechanisms for the protective effect of APOE ε2
    • Suri S, Heise V, Trachtenberg AJ, Mackay CE. The forgotten APOE allele: a review of the evidence and suggested mechanisms for the protective effect of APOE ε2. Neurosci Biobehav Rev. 2013;37(10 Pt 2):2878-2886.
    • (2013) Neurosci Biobehav Rev , vol.37 , Issue.10 , pp. 2878-2886
    • Suri, S.1    Heise, V.2    Trachtenberg, A.J.3    Mackay, C.E.4
  • 57
    • 84892672453 scopus 로고    scopus 로고
    • Cognitive and social lifestyle: Links with neuropathology and cognition in late life
    • Bennett DA, Arnold SE, Valenzuela MJ, Brayne C, Schneider JA. Cognitive and social lifestyle: links with neuropathology and cognition in late life. Acta Neuropathol. 2014;127(1):137-150.
    • (2014) Acta Neuropathol , vol.127 , Issue.1 , pp. 137-150
    • Bennett, D.A.1    Arnold, S.E.2    Valenzuela, M.J.3    Brayne, C.4    Schneider, J.A.5
  • 58
    • 84891939289 scopus 로고    scopus 로고
    • Healthy lifestyles reduce the incidence of chronic diseases and dementia: Evidence from the Caerphilly cohort study
    • Elwood P, Galante J, Pickering J, et al. Healthy lifestyles reduce the incidence of chronic diseases and dementia: evidence from the Caerphilly cohort study. PLoS One. 2013;8(12):e81877.
    • (2013) PLoS One , vol.8 , Issue.12
    • Elwood, P.1    Galante, J.2    Pickering, J.3
  • 59
    • 84859500528 scopus 로고    scopus 로고
    • Association of lifetime cognitive engagement and low β-amyloid deposition
    • Landau SM, Marks SM, Mormino EC, et al. Association of lifetime cognitive engagement and low β-amyloid deposition. Arch Neurol. 2012;69(5):623-629.
    • (2012) Arch Neurol , vol.69 , Issue.5 , pp. 623-629
    • Landau, S.M.1    Marks, S.M.2    Mormino, E.C.3
  • 60
    • 84923347203 scopus 로고    scopus 로고
    • Lifelong brain health is a lifelong challenge: From evolutionary principles to empirical evidence
    • Mattson MP. Lifelong brain health is a lifelong challenge: from evolutionary principles to empirical evidence. Ageing Res Rev. 2015;20:37-45.
    • (2015) Ageing Res Rev , vol.20 , pp. 37-45
    • Mattson, M.P.1
  • 61
    • 84858332475 scopus 로고    scopus 로고
    • Lifestyle behavior pattern is associated with different levels of risk for incident dementia and Alzheimer's disease: The Cache County study
    • Norton MC, Dew J, Smith H, et al; Cache County Investigators. Lifestyle behavior pattern is associated with different levels of risk for incident dementia and Alzheimer's disease: the Cache County study. J Am Geriatr Soc. 2012;60(3):405-412.
    • (2012) J Am Geriatr Soc , vol.60 , Issue.3 , pp. 405-412
    • Norton, M.C.1    Dew, J.2    Smith, H.3
  • 62
    • 84880703597 scopus 로고    scopus 로고
    • A review of multidomain interventions to support healthy cognitive ageing
    • Schneider N, Yvon C. A review of multidomain interventions to support healthy cognitive ageing. J Nutr Health Aging. 2013;17(3):252-257.
    • (2013) J Nutr Health Aging , vol.17 , Issue.3 , pp. 252-257
    • Schneider, N.1    Yvon, C.2
  • 64
    • 2442419100 scopus 로고    scopus 로고
    • Apolipoprotein E ε4 count affects age at onset of Alzheimer disease, but not lifetime susceptibility: The Cache County Study
    • Khachaturian AS, Corcoran CD, Mayer LS, Zandi PP, Breitner JC; Cache County Study Investigators. Apolipoprotein E ε4 count affects age at onset of Alzheimer disease, but not lifetime susceptibility: the Cache County Study. Arch Gen Psychiatry. 2004;61(5):518-524.
    • (2004) Arch Gen Psychiatry , vol.61 , Issue.5 , pp. 518-524
    • Khachaturian, A.S.1    Corcoran, C.D.2    Mayer, L.S.3    Zandi, P.P.4    Breitner, J.C.5
  • 66
    • 84895746988 scopus 로고    scopus 로고
    • Amyloid deposition is decreasing in aging brains: An autopsy study of 1599 older people
    • Kövari E, Herrmann FR, Bouras C, Gold G. Amyloid deposition is decreasing in aging brains: an autopsy study of 1599 older people. Neurology. 2014;82(4):326-331.
    • (2014) Neurology , vol.82 , Issue.4 , pp. 326-331
    • Kövari, E.1    Herrmann, F.R.2    Bouras, C.3    Gold, G.4
  • 67
    • 54049152421 scopus 로고    scopus 로고
    • MRI correlates of neurofibrillary tangle pathology at autopsy: A voxel-based morphometry study
    • Whitwell JL, Josephs KA, Murray ME, et al. MRI correlates of neurofibrillary tangle pathology at autopsy: a voxel-based morphometry study. Neurology. 2008;71(10):743-749.
    • (2008) Neurology , vol.71 , Issue.10 , pp. 743-749
    • Whitwell, J.L.1    Josephs, K.A.2    Murray, M.E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.