A Systems Biology Approach Identifies FUT8 as a Driver of Melanoma Metastasis

Cancer Cell

Volumn 31, Issue 6, 2017, Pages 804-819.e7

  Agrawal, Praveen ^a,b   Fontanals Cirera, Barbara ^a   Sokolova, Elena ^a   Jacob, Samson ^a   Vaiana, Christopher A ^b   Argibay, Diana ^a   Davalos, Veronica ^a   McDermott, Meagan ^b   Nayak, Shruti ^a   Darvishian, Farbod ^a   Castillo, Mireia ^c   Ueberheide, Beatrix ^a   Osman, Iman ^a   Fenyö, David ^a   Mahal, Lara K ^a,b   Hernando, Eva ^a  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NEW YORK UNIVERSITY   (United States)

^c MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

core fucosylation; FUT8; glycomics; glycosylation; L1CAM; lectin array; lectin microarray; metastasis; metastatic melanoma; primary melanoma

Indexed keywords

ALPHA 2 ANTIPLASMIN; DOXORUBICIN; FUCOSYLTRANSFERASE; FUT1 ENZYME; FUT2 ENZYME; GLYCOPROTEIN; GLYCOSYLATED PROTEIN; HEPATOCYTE NUCLEAR FACTOR 3BETA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERFERON REGULATORY FACTOR 1; L1CAM PROTEIN; LECTIN; MESSENGER RNA; N ACETYLGALACTOSAMINE; PLASMIN; PLASMINOGEN ACTIVATOR; SIALYLTRANSFERASE; SMAD3 PROTEIN; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR RUNX1; TRANSCRIPTION FACTOR SOX10; TRANSCRIPTION FACTOR SOX2; TRANSFORMING GROWTH FACTOR BETA; UNCLASSIFIED DRUG; GLYCOPROTEIN 6-ALPHA-L-FUCOSYLTRANSFERASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL MIGRATION; CONTROLLED STUDY; DOWN REGULATION; FUCOSYLATION; GLYCOSYLATION; IN VITRO STUDY; IN VIVO STUDY; MELANOMA; METASTASIS; METASTASIS INHIBITION; MOUSE; NONHUMAN; PRIORITY JOURNAL; SYSTEMS BIOLOGY; TUMOR INVASION; UPREGULATION; ANIMAL; GENE EXPRESSION REGULATION; GENE SILENCING; GENETICS; HUMAN; METABOLISM; PATHOLOGY; PHYSIOLOGY; PROCEDURES;

ANIMALS; FUCOSYLTRANSFERASES; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE SILENCING; GLYCOPROTEINS; GLYCOSYLATION; HUMANS; MELANOMA; MICE; NEOPLASM INVASIVENESS; NEOPLASM METASTASIS; SYSTEMS BIOLOGY;

EID: 85020689386     PISSN: 15356108     EISSN: 18783686     Source Type: Journal    
DOI: 10.1016/j.ccell.2017.05.007     Document Type: Article

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