-
1
-
-
84881192460
-
BET bromodomains mediate transcriptional pause release in heart failure
-
Anand P., Brown J.D., Lin C.Y., Qi J., Zhang R., Artero P.C., Alaiti M.A., Bullard J., Alazem K., Margulies K.B., et al. BET bromodomains mediate transcriptional pause release in heart failure. Cell 2013, 154:569-582.
-
(2013)
Cell
, vol.154
, pp. 569-582
-
-
Anand, P.1
Brown, J.D.2
Lin, C.Y.3
Qi, J.4
Zhang, R.5
Artero, P.C.6
Alaiti, M.A.7
Bullard, J.8
Alazem, K.9
Margulies, K.B.10
-
2
-
-
0030480969
-
The CBP co-activator is a histone acetyltransferase
-
Bannister A.J., Kouzarides T. The CBP co-activator is a histone acetyltransferase. Nature 1996, 384:641-643.
-
(1996)
Nature
, vol.384
, pp. 641-643
-
-
Bannister, A.J.1
Kouzarides, T.2
-
3
-
-
84862738480
-
BET domain co-regulators in obesity, inflammation and cancer
-
Belkina A.C., Denis G.V. BET domain co-regulators in obesity, inflammation and cancer. Nat. Rev. Cancer 2012, 12:465-477.
-
(2012)
Nat. Rev. Cancer
, vol.12
, pp. 465-477
-
-
Belkina, A.C.1
Denis, G.V.2
-
4
-
-
35348816030
-
Conserved P-TEFb-interacting domain of BRD4 inhibits HIV transcription
-
Bisgrove D.A., Mahmoudi T., Henklein P., Verdin E. Conserved P-TEFb-interacting domain of BRD4 inhibits HIV transcription. Proc. Natl. Acad. Sci. USA 2007, 104:13690-13695.
-
(2007)
Proc. Natl. Acad. Sci. USA
, vol.104
, pp. 13690-13695
-
-
Bisgrove, D.A.1
Mahmoudi, T.2
Henklein, P.3
Verdin, E.4
-
5
-
-
79955410483
-
A small molecule binding to the coactivator CREB-binding protein blocks apoptosis in cardiomyocytes
-
Borah J.C., Mujtaba S., Karakikes I., Zeng L., Muller M., Patel J., Moshkina N., Morohashi K., Zhang W., Gerona-Navarro G., et al. A small molecule binding to the coactivator CREB-binding protein blocks apoptosis in cardiomyocytes. Chem. Biol. 2011, 18:531-541.
-
(2011)
Chem. Biol.
, vol.18
, pp. 531-541
-
-
Borah, J.C.1
Mujtaba, S.2
Karakikes, I.3
Zeng, L.4
Muller, M.5
Patel, J.6
Moshkina, N.7
Morohashi, K.8
Zhang, W.9
Gerona-Navarro, G.10
-
6
-
-
80054984945
-
Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia
-
Dawson M.A., Prinjha R.K., Dittmann A., Giotopoulos G., Bantscheff M., Chan W.I., Robson S.C., Chung C.W., Hopf C., Savitski M.M., et al. Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia. Nature 2011, 478:529-533.
-
(2011)
Nature
, vol.478
, pp. 529-533
-
-
Dawson, M.A.1
Prinjha, R.K.2
Dittmann, A.3
Giotopoulos, G.4
Bantscheff, M.5
Chan, W.I.6
Robson, S.C.7
Chung, C.W.8
Hopf, C.9
Savitski, M.M.10
-
7
-
-
80052955256
-
BET bromodomain inhibition as a therapeutic strategy to target c-Myc
-
Delmore J.E., Issa G.C., Lemieux M.E., Rahl P.B., Shi J., Jacobs H.M., Kastritis E., Gilpatrick T., Paranal R.M., Qi J., et al. BET bromodomain inhibition as a therapeutic strategy to target c-Myc. Cell 2011, 146:904-917.
-
(2011)
Cell
, vol.146
, pp. 904-917
-
-
Delmore, J.E.1
Issa, G.C.2
Lemieux, M.E.3
Rahl, P.B.4
Shi, J.5
Jacobs, H.M.6
Kastritis, E.7
Gilpatrick, T.8
Paranal, R.M.9
Qi, J.10
-
8
-
-
84860832960
-
BRD4 is an atypical kinase that phosphorylates serine2 of the RNA polymerase II carboxy-terminal domain
-
Devaiah B.N., Lewis B.A., Cherman N., Hewitt M.C., Albrecht B.K., Robey P.G., Ozato K., Sims R.J., Singer D.S. BRD4 is an atypical kinase that phosphorylates serine2 of the RNA polymerase II carboxy-terminal domain. Proc. Natl. Acad. Sci. USA 2012, 109:6927-6932.
-
(2012)
Proc. Natl. Acad. Sci. USA
, vol.109
, pp. 6927-6932
-
-
Devaiah, B.N.1
Lewis, B.A.2
Cherman, N.3
Hewitt, M.C.4
Albrecht, B.K.5
Robey, P.G.6
Ozato, K.7
Sims, R.J.8
Singer, D.S.9
-
9
-
-
65349123354
-
A genome-scale RNAi screen for Oct4 modulators defines a role of the Paf1 complex for embryonic stem cell identity
-
Ding L., Paszkowski-Rogacz M., Nitzsche A., Slabicki M.M., Heninger A.K., de Vries I., Kittler R., Junqueira M., Shevchenko A., Schulz H., et al. A genome-scale RNAi screen for Oct4 modulators defines a role of the Paf1 complex for embryonic stem cell identity. Cell Stem Cell 2009, 4:403-415.
-
(2009)
Cell Stem Cell
, vol.4
, pp. 403-415
-
-
Ding, L.1
Paszkowski-Rogacz, M.2
Nitzsche, A.3
Slabicki, M.M.4
Heninger, A.K.5
de Vries, I.6
Kittler, R.7
Junqueira, M.8
Shevchenko, A.9
Schulz, H.10
-
10
-
-
46149110511
-
An RNAi screen of chromatin proteins identifies Tip60-p400 as a regulator of embryonic stem cell identity
-
Fazzio T.G., Huff J.T., Panning B. An RNAi screen of chromatin proteins identifies Tip60-p400 as a regulator of embryonic stem cell identity. Cell 2008, 134:162-174.
-
(2008)
Cell
, vol.134
, pp. 162-174
-
-
Fazzio, T.G.1
Huff, J.T.2
Panning, B.3
-
11
-
-
78650847770
-
Selective inhibition of BET bromodomains
-
Filippakopoulos P., Qi J., Picaud S., Shen Y., Smith W.B., Fedorov O., Morse E.M., Keates T., Hickman T.T., Felletar I., et al. Selective inhibition of BET bromodomains. Nature 2010, 468:1067-1073.
-
(2010)
Nature
, vol.468
, pp. 1067-1073
-
-
Filippakopoulos, P.1
Qi, J.2
Picaud, S.3
Shen, Y.4
Smith, W.B.5
Fedorov, O.6
Morse, E.M.7
Keates, T.8
Hickman, T.T.9
Felletar, I.10
-
12
-
-
84859181036
-
Histone recognition and large-scale structural analysis of the human bromodomain family
-
Filippakopoulos P., Picaud S., Mangos M., Keates T., Lambert J.P., Barsyte-Lovejoy D., Felletar I., Volkmer R., Müller S., Pawson T., et al. Histone recognition and large-scale structural analysis of the human bromodomain family. Cell 2012, 149:214-231.
-
(2012)
Cell
, vol.149
, pp. 214-231
-
-
Filippakopoulos, P.1
Picaud, S.2
Mangos, M.3
Keates, T.4
Lambert, J.P.5
Barsyte-Lovejoy, D.6
Felletar, I.7
Volkmer, R.8
Müller, S.9
Pawson, T.10
-
13
-
-
34347346076
-
Regulation of P-TEFb elongation complex activity by CDK9 acetylation
-
Fu J., Yoon H.G., Qin J., Wong J. Regulation of P-TEFb elongation complex activity by CDK9 acetylation. Mol. Cell. Biol. 2007, 27:4641-4651.
-
(2007)
Mol. Cell. Biol.
, vol.27
, pp. 4641-4651
-
-
Fu, J.1
Yoon, H.G.2
Qin, J.3
Wong, J.4
-
14
-
-
0026608175
-
The bromodomain: a conserved sequence found in human, Drosophila and yeast proteins
-
Haynes S.R., Dollard C., Winston F., Beck S., Trowsdale J., Dawid I.B. The bromodomain: a conserved sequence found in human, Drosophila and yeast proteins. Nucleic Acids Res. 1992, 20:2603.
-
(1992)
Nucleic Acids Res.
, vol.20
, pp. 2603
-
-
Haynes, S.R.1
Dollard, C.2
Winston, F.3
Beck, S.4
Trowsdale, J.5
Dawid, I.B.6
-
15
-
-
84888015137
-
Super-enhancers in the control of cell identity and disease
-
Hnisz D., Abraham B.J., Lee T.I., Lau A., Saint-André V., Sigova A.A., Hoke H.A., Young R.A. Super-enhancers in the control of cell identity and disease. Cell 2013, 155:934-947.
-
(2013)
Cell
, vol.155
, pp. 934-947
-
-
Hnisz, D.1
Abraham, B.J.2
Lee, T.I.3
Lau, A.4
Saint-André, V.5
Sigova, A.A.6
Hoke, H.A.7
Young, R.A.8
-
16
-
-
0036091456
-
Growth and early postimplantation defects in mice deficient for the bromodomain-containing protein Brd4
-
Houzelstein D., Bullock S.L., Lynch D.E., Grigorieva E.F., Wilson V.A., Beddington R.S. Growth and early postimplantation defects in mice deficient for the bromodomain-containing protein Brd4. Mol. Cell. Biol. 2002, 22:3794-3802.
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 3794-3802
-
-
Houzelstein, D.1
Bullock, S.L.2
Lynch, D.E.3
Grigorieva, E.F.4
Wilson, V.A.5
Beddington, R.S.6
-
17
-
-
33746773659
-
Dissecting self-renewal in stem cells with RNA interference
-
Ivanova N., Dobrin R., Lu R., Kotenko I., Levorse J., DeCoste C., Schafer X., Lun Y., Lemischka I.R. Dissecting self-renewal in stem cells with RNA interference. Nature 2006, 442:533-538.
-
(2006)
Nature
, vol.442
, pp. 533-538
-
-
Ivanova, N.1
Dobrin, R.2
Lu, R.3
Kotenko, I.4
Levorse, J.5
DeCoste, C.6
Schafer, X.7
Lun, Y.8
Lemischka, I.R.9
-
18
-
-
0031281866
-
Identification and characterization of BRDT: A testis-specific gene related to the bromodomain genes RING3 and Drosophila fsh
-
Jones M.H., Numata M., Shimane M. Identification and characterization of BRDT: A testis-specific gene related to the bromodomain genes RING3 and Drosophila fsh. Genomics 1997, 45:529-534.
-
(1997)
Genomics
, vol.45
, pp. 529-534
-
-
Jones, M.H.1
Numata, M.2
Shimane, M.3
-
19
-
-
78649751050
-
Sox2 is essential for formation of trophectoderm in the preimplantation embryo
-
Keramari M., Razavi J., Ingman K.A., Patsch C., Edenhofer F., Ward C.M., Kimber S.J. Sox2 is essential for formation of trophectoderm in the preimplantation embryo. PLoS ONE 2010, 5:e13952.
-
(2010)
PLoS ONE
, vol.5
, pp. e13952
-
-
Keramari, M.1
Razavi, J.2
Ingman, K.A.3
Patsch, C.4
Edenhofer, F.5
Ward, C.M.6
Kimber, S.J.7
-
20
-
-
41549115095
-
The double bromodomain proteins Brd2 and Brd3 couple histone acetylation to transcription
-
LeRoy G., Rickards B., Flint S.J. The double bromodomain proteins Brd2 and Brd3 couple histone acetylation to transcription. Mol. Cell 2008, 30:51-60.
-
(2008)
Mol. Cell
, vol.30
, pp. 51-60
-
-
LeRoy, G.1
Rickards, B.2
Flint, S.J.3
-
21
-
-
84864601941
-
The histone acetyltransferase MOF is a key regulator of the embryonic stem cell core transcriptional network
-
Li X., Li L., Pandey R., Byun J.S., Gardner K., Qin Z., Dou Y. The histone acetyltransferase MOF is a key regulator of the embryonic stem cell core transcriptional network. Cell Stem Cell 2012, 11:163-178.
-
(2012)
Cell Stem Cell
, vol.11
, pp. 163-178
-
-
Li, X.1
Li, L.2
Pandey, R.3
Byun, J.S.4
Gardner, K.5
Qin, Z.6
Dou, Y.7
-
22
-
-
84876222028
-
Selective inhibition of tumor oncogenes by disruption of super-enhancers
-
Lovén J., Hoke H.A., Lin C.Y., Lau A., Orlando D.A., Vakoc C.R., Bradner J.E., Lee T.I., Young R.A. Selective inhibition of tumor oncogenes by disruption of super-enhancers. Cell 2013, 153:320-334.
-
(2013)
Cell
, vol.153
, pp. 320-334
-
-
Lovén, J.1
Hoke, H.A.2
Lin, C.Y.3
Lau, A.4
Orlando, D.A.5
Vakoc, C.R.6
Bradner, J.E.7
Lee, T.I.8
Young, R.A.9
-
23
-
-
79551624666
-
Sequence-specific regulator Prdm14 safeguards mouse ESCs from entering extraembryonic endoderm fates
-
Ma Z., Swigut T., Valouev A., Rada-Iglesias A., Wysocka J. Sequence-specific regulator Prdm14 safeguards mouse ESCs from entering extraembryonic endoderm fates. Nat. Struct. Mol. Biol. 2011, 18:120-127.
-
(2011)
Nat. Struct. Mol. Biol.
, vol.18
, pp. 120-127
-
-
Ma, Z.1
Swigut, T.2
Valouev, A.3
Rada-Iglesias, A.4
Wysocka, J.5
-
24
-
-
33745865934
-
Chromatin in pluripotent embryonic stem cells and differentiation
-
Meshorer E., Misteli T. Chromatin in pluripotent embryonic stem cells and differentiation. Nat. Rev. Mol. Cell Biol. 2006, 7:540-546.
-
(2006)
Nat. Rev. Mol. Cell Biol.
, vol.7
, pp. 540-546
-
-
Meshorer, E.1
Misteli, T.2
-
25
-
-
0037806031
-
The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cells
-
Mitsui K., Tokuzawa Y., Itoh H., Segawa K., Murakami M., Takahashi K., Maruyama M., Maeda M., Yamanaka S. The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cells. Cell 2003, 113:631-642.
-
(2003)
Cell
, vol.113
, pp. 631-642
-
-
Mitsui, K.1
Tokuzawa, Y.2
Itoh, H.3
Segawa, K.4
Murakami, M.5
Takahashi, K.6
Maruyama, M.7
Maeda, M.8
Yamanaka, S.9
-
26
-
-
84855516244
-
Nonoverlapping functions of the Polycomb group Cbx family of proteins in embryonic stem cells
-
Morey L., Pascual G., Cozzuto L., Roma G., Wutz A., Benitah S.A., Di Croce L. Nonoverlapping functions of the Polycomb group Cbx family of proteins in embryonic stem cells. Cell Stem Cell 2012, 10:47-62.
-
(2012)
Cell Stem Cell
, vol.10
, pp. 47-62
-
-
Morey, L.1
Pascual, G.2
Cozzuto, L.3
Roma, G.4
Wutz, A.5
Benitah, S.A.6
Di Croce, L.7
-
27
-
-
70349669271
-
Cooperative binding of two acetylation marks on a histone tail by a single bromodomain
-
Morinière J., Rousseaux S., Steuerwald U., Soler-López M., Curtet S., Vitte A.L., Govin J., Gaucher J., Sadoul K., Hart D.J., et al. Cooperative binding of two acetylation marks on a histone tail by a single bromodomain. Nature 2009, 461:664-668.
-
(2009)
Nature
, vol.461
, pp. 664-668
-
-
Morinière, J.1
Rousseaux, S.2
Steuerwald, U.3
Soler-López, M.4
Curtet, S.5
Vitte, A.L.6
Govin, J.7
Gaucher, J.8
Sadoul, K.9
Hart, D.J.10
-
28
-
-
78650806593
-
Suppression of inflammation by a synthetic histone mimic
-
Nicodeme E., Jeffrey K.L., Schaefer U., Beinke S., Dewell S., Chung C.W., Chandwani R., Marazzi I., Wilson P., Coste H., et al. Suppression of inflammation by a synthetic histone mimic. Nature 2010, 468:1119-1123.
-
(2010)
Nature
, vol.468
, pp. 1119-1123
-
-
Nicodeme, E.1
Jeffrey, K.L.2
Schaefer, U.3
Beinke, S.4
Dewell, S.5
Chung, C.W.6
Chandwani, R.7
Marazzi, I.8
Wilson, P.9
Coste, H.10
-
29
-
-
84856747744
-
Genetic inactivation of the polycomb repressive complex 2 in Tcell acute lymphoblastic leukemia
-
Ntziachristos P., Tsirigos A., Van Vlierberghe P., Nedjic J., Trimarchi T., Flaherty M.S., Ferres-Marco D., da Ros V., Tang Z., Siegle J., et al. Genetic inactivation of the polycomb repressive complex 2 in Tcell acute lymphoblastic leukemia. Nat. Med. 2012, 18:298-301.
-
(2012)
Nat. Med.
, vol.18
, pp. 298-301
-
-
Ntziachristos, P.1
Tsirigos, A.2
Van Vlierberghe, P.3
Nedjic, J.4
Trimarchi, T.5
Flaherty, M.S.6
Ferres-Marco, D.7
da Ros, V.8
Tang, Z.9
Siegle, J.10
-
30
-
-
0030606239
-
The transcriptional coactivators p300 and CBP are histone acetyltransferases
-
Ogryzko V.V., Schiltz R.L., Russanova V., Howard B.H., Nakatani Y. The transcriptional coactivators p300 and CBP are histone acetyltransferases. Cell 1996, 87:953-959.
-
(1996)
Cell
, vol.87
, pp. 953-959
-
-
Ogryzko, V.V.1
Schiltz, R.L.2
Russanova, V.3
Howard, B.H.4
Nakatani, Y.5
-
31
-
-
84859218238
-
Chromatin-modifying enzymes as modulators of reprogramming
-
Onder T.T., Kara N., Cherry A., Sinha A.U., Zhu N., Bernt K.M., Cahan P., Marcarci B.O., Unternaehrer J., Gupta P.B., et al. Chromatin-modifying enzymes as modulators of reprogramming. Nature 2012, 483:598-602.
-
(2012)
Nature
, vol.483
, pp. 598-602
-
-
Onder, T.T.1
Kara, N.2
Cherry, A.3
Sinha, A.U.4
Zhu, N.5
Bernt, K.M.6
Cahan, P.7
Marcarci, B.O.8
Unternaehrer, J.9
Gupta, P.B.10
-
32
-
-
69149110152
-
Stoichiometric and temporal requirements of Oct4, Sox2, Klf4, and c-Myc expression for efficient human iPSC induction and differentiation
-
Papapetrou E.P., Tomishima M.J., Chambers S.M., Mica Y., Reed E., Menon J., Tabar V., Mo Q., Studer L., Sadelain M. Stoichiometric and temporal requirements of Oct4, Sox2, Klf4, and c-Myc expression for efficient human iPSC induction and differentiation. Proc. Natl. Acad. Sci. USA 2009, 106:12759-12764.
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 12759-12764
-
-
Papapetrou, E.P.1
Tomishima, M.J.2
Chambers, S.M.3
Mica, Y.4
Reed, E.5
Menon, J.6
Tabar, V.7
Mo, Q.8
Studer, L.9
Sadelain, M.10
-
33
-
-
0034895829
-
Oct-4: gatekeeper in the beginnings of mammalian development
-
Pesce M., Schöler H.R. Oct-4: gatekeeper in the beginnings of mammalian development. Stem Cells 2001, 19:271-278.
-
(2001)
Stem Cells
, vol.19
, pp. 271-278
-
-
Pesce, M.1
Schöler, H.R.2
-
35
-
-
78249240545
-
Mutations in FLVCR1 cause posterior column ataxia and retinitis pigmentosa
-
Rajadhyaksha A.M., Elemento O., Puffenberger E.G., Schierberl K.C., Xiang J.Z., Putorti M.L., Berciano J., Poulin C., Brais B., Michaelides M., et al. Mutations in FLVCR1 cause posterior column ataxia and retinitis pigmentosa. Am. J. Hum. Genet. 2010, 87:643-654.
-
(2010)
Am. J. Hum. Genet.
, vol.87
, pp. 643-654
-
-
Rajadhyaksha, A.M.1
Elemento, O.2
Puffenberger, E.G.3
Schierberl, K.C.4
Xiang, J.Z.5
Putorti, M.L.6
Berciano, J.7
Poulin, C.8
Brais, B.9
Michaelides, M.10
-
36
-
-
70149105669
-
The role of human bromodomains in chromatin biology and gene transcription
-
Sanchez R., Zhou M.M. The role of human bromodomains in chromatin biology and gene transcription. Curr. Opin. Drug Discov. Devel. 2009, 12:659-665.
-
(2009)
Curr. Opin. Drug Discov. Devel.
, vol.12
, pp. 659-665
-
-
Sanchez, R.1
Zhou, M.M.2
-
37
-
-
73349095689
-
Smarcc1/Baf155 couples self-renewal gene repression with changes in chromatin structure in mouse embryonic stem cells
-
Schaniel C., Ang Y.S., Ratnakumar K., Cormier C., James T., Bernstein E., Lemischka I.R., Paddison P.J. Smarcc1/Baf155 couples self-renewal gene repression with changes in chromatin structure in mouse embryonic stem cells. Stem Cells 2009, 27:2979-2991.
-
(2009)
Stem Cells
, vol.27
, pp. 2979-2991
-
-
Schaniel, C.1
Ang, Y.S.2
Ratnakumar, K.3
Cormier, C.4
James, T.5
Bernstein, E.6
Lemischka, I.R.7
Paddison, P.J.8
-
38
-
-
84886045045
-
BRD4 sustains melanoma proliferation and represents a new target for epigenetic therapy
-
Segura M.F., Fontanals-Cirera B., Gaziel-Sovran A., Guijarro M.V., Hanniford D., Zhang G., González-Gomez P., Morante M., Jubierre L., Zhang W., et al. BRD4 sustains melanoma proliferation and represents a new target for epigenetic therapy. Cancer Res. 2013, 73:6264-6276.
-
(2013)
Cancer Res.
, vol.73
, pp. 6264-6276
-
-
Segura, M.F.1
Fontanals-Cirera, B.2
Gaziel-Sovran, A.3
Guijarro, M.V.4
Hanniford, D.5
Zhang, G.6
González-Gomez, P.7
Morante, M.8
Jubierre, L.9
Zhang, W.10
-
39
-
-
63849121338
-
Double bromodomain-containing gene Brd2 is essential for embryonic development in mouse
-
Shang E., Wang X., Wen D., Greenberg D.A., Wolgemuth D.J. Double bromodomain-containing gene Brd2 is essential for embryonic development in mouse. Dev. Dyn. 2009, 238:908-917.
-
(2009)
Dev. Dyn.
, vol.238
, pp. 908-917
-
-
Shang, E.1
Wang, X.2
Wen, D.3
Greenberg, D.A.4
Wolgemuth, D.J.5
-
40
-
-
0026580006
-
Brahma: a regulator of Drosophila homeotic genes structurally related to the yeast transcriptional activator SNF2/SWI2
-
Tamkun J.W., Deuring R., Scott M.P., Kissinger M., Pattatucci A.M., Kaufman T.C., Kennison J.A. brahma: a regulator of Drosophila homeotic genes structurally related to the yeast transcriptional activator SNF2/SWI2. Cell 1992, 68:561-572.
-
(1992)
Cell
, vol.68
, pp. 561-572
-
-
Tamkun, J.W.1
Deuring, R.2
Scott, M.P.3
Kissinger, M.4
Pattatucci, A.M.5
Kaufman, T.C.6
Kennison, J.A.7
-
41
-
-
79958263080
-
Pluripotency factors in embryonic stem cells regulate differentiation into germ layers
-
Thomson M., Liu S.J., Zou L.N., Smith Z., Meissner A., Ramanathan S. Pluripotency factors in embryonic stem cells regulate differentiation into germ layers. Cell 2011, 145:875-889.
-
(2011)
Cell
, vol.145
, pp. 875-889
-
-
Thomson, M.1
Liu, S.J.2
Zou, L.N.3
Smith, Z.4
Meissner, A.5
Ramanathan, S.6
-
42
-
-
84859539293
-
Distinct lineage specification roles for NANOG, OCT4, and SOX2 in human embryonic stem cells
-
Wang Z., Oron E., Nelson B., Razis S., Ivanova N. Distinct lineage specification roles for NANOG, OCT4, and SOX2 in human embryonic stem cells. Cell Stem Cell 2012, 10:440-454.
-
(2012)
Cell Stem Cell
, vol.10
, pp. 440-454
-
-
Wang, Z.1
Oron, E.2
Nelson, B.3
Razis, S.4
Ivanova, N.5
-
43
-
-
84876216563
-
Master transcription factors and mediator establish super-enhancers at key cell identity genes
-
Whyte W.A., Orlando D.A., Hnisz D., Abraham B.J., Lin C.Y., Kagey M.H., Rahl P.B., Lee T.I., Young R.A. Master transcription factors and mediator establish super-enhancers at key cell identity genes. Cell 2013, 153:307-319.
-
(2013)
Cell
, vol.153
, pp. 307-319
-
-
Whyte, W.A.1
Orlando, D.A.2
Hnisz, D.3
Abraham, B.J.4
Lin, C.Y.5
Kagey, M.H.6
Rahl, P.B.7
Lee, T.I.8
Young, R.A.9
-
44
-
-
70249141638
-
Regulation of aurora B expression by the bromodomain protein Brd4
-
You J., Li Q., Wu C., Kim J., Ottinger M., Howley P.M. Regulation of aurora B expression by the bromodomain protein Brd4. Mol. Cell. Biol. 2009, 29:5094-5103.
-
(2009)
Mol. Cell. Biol.
, vol.29
, pp. 5094-5103
-
-
You, J.1
Li, Q.2
Wu, C.3
Kim, J.4
Ottinger, M.5
Howley, P.M.6
-
45
-
-
84865222098
-
Down-regulation of NF-κB transcriptional activity in HIV-associated kidney disease by BRD4 inhibition
-
Zhang G., Liu R., Zhong Y., Plotnikov A.N., Zhang W., Zeng L., Rusinova E., Gerona-Nevarro G., Moshkina N., Joshua J., et al. Down-regulation of NF-κB transcriptional activity in HIV-associated kidney disease by BRD4 inhibition. J.Biol. Chem. 2012, 287:28840-28851.
-
(2012)
J.Biol. Chem.
, vol.287
, pp. 28840-28851
-
-
Zhang, G.1
Liu, R.2
Zhong, Y.3
Plotnikov, A.N.4
Zhang, W.5
Zeng, L.6
Rusinova, E.7
Gerona-Nevarro, G.8
Moshkina, N.9
Joshua, J.10
-
46
-
-
84889257680
-
Structure-guided design of potent diazobenzene inhibitors for the BET bromodomains
-
Zhang G., Plotnikov A.N., Rusinova E., Shen T., Morohashi K., Joshua J., Zeng L., Mujtaba S., Ohlmeyer M., Zhou M.M. Structure-guided design of potent diazobenzene inhibitors for the BET bromodomains. J.Med. Chem. 2013, 56:9251-9264.
-
(2013)
J.Med. Chem.
, vol.56
, pp. 9251-9264
-
-
Zhang, G.1
Plotnikov, A.N.2
Rusinova, E.3
Shen, T.4
Morohashi, K.5
Joshua, J.6
Zeng, L.7
Mujtaba, S.8
Ohlmeyer, M.9
Zhou, M.M.10
-
47
-
-
80455122751
-
Gene bookmarking accelerates the kinetics of post-mitotic transcriptional re-activation
-
Zhao R., Nakamura T., Fu Y., Lazar Z., Spector D.L. Gene bookmarking accelerates the kinetics of post-mitotic transcriptional re-activation. Nat. Cell Biol. 2011, 13:1295-1304.
-
(2011)
Nat. Cell Biol.
, vol.13
, pp. 1295-1304
-
-
Zhao, R.1
Nakamura, T.2
Fu, Y.3
Lazar, Z.4
Spector, D.L.5
-
48
-
-
80055000824
-
RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia
-
Zuber J., Shi J., Wang E., Rappaport A.R., Herrmann H., Sison E.A., Magoon D., Qi J., Blatt K., Wunderlich M., et al. RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia. Nature 2011, 478:524-528.
-
(2011)
Nature
, vol.478
, pp. 524-528
-
-
Zuber, J.1
Shi, J.2
Wang, E.3
Rappaport, A.R.4
Herrmann, H.5
Sison, E.A.6
Magoon, D.7
Qi, J.8
Blatt, K.9
Wunderlich, M.10
|