Loss of α1,6-fucosyltransferase inhibits chemical-induced hepatocellular carcinoma and tumorigenesis by down-regulating several cell signaling pathways

FASEB Journal

Volumn 29, Issue 8, 2015, Pages 3217-3227

  Wang, Yuqin ^a   Fukuda, Tomohiko ^a   Isaji, Tomoya ^a   Lu, Jishun ^a   Im, Sanghun ^a   Hang, Qinglei ^a   Gu, Wei ^a   Hou, Sicong ^a   Ohtsubo, Kazuaki ^b   Gu, Jianguo ^a  

^a TOHOKU PHARMACEUTICAL UNIVERSITY   (Japan)

^b KUMAMOTO UNIVERSITY   (Japan)

Author keywords

Cell proliferation; Glycosyltransferase; N glycosylation

Indexed keywords

ALPHA 1,6 FUCOSYLTRANSFERASE INHIBITOR; DIETHYLNITROSAMINE; EPIDERMAL GROWTH FACTOR; GLYCOSYLTRANSFERASE INHIBITOR; SCATTER FACTOR; UNCLASSIFIED DRUG; FUCOSYLTRANSFERASE; GLYCOPROTEIN 6-ALPHA-L-FUCOSYLTRANSFERASE;

ACUTE PHASE RESPONSE; ANIMAL EXPERIMENT; ARTICLE; CARCINOGENESIS; CELL PROLIFERATION; CONTROLLED STUDY; DOWN REGULATION; FUCOSYLATION; HEPATOCELLULAR CARCINOMA CELL LINE; HEPG2 CELL LINE; HUMAN; HUMAN CELL; LIVER CELL CARCINOMA; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TUMOR GROWTH; TUMOR XENOGRAFT; ANIMAL; GENETICS; LIVER TUMOR; MOUSE; TUMOR CELL LINE;

MUS;

ANIMALS; CARCINOGENESIS; CARCINOMA, HEPATOCELLULAR; CELL LINE, TUMOR; DOWN-REGULATION; EPIDERMAL GROWTH FACTOR; FUCOSYLTRANSFERASES; HEP G2 CELLS; HEPATOCYTE GROWTH FACTOR; HUMANS; LIVER NEOPLASMS; MALE; MICE; SIGNAL TRANSDUCTION;

EID: 84940421899     PISSN: 08926638     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.15-270710     Document Type: Article

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