The transcription factor ATF2 promotes melanoma metastasis by suppressing protein fucosylation

Science Signaling

Volumn 8, Issue 406, 2015, Pages

  Lau, Eric ^a,c   Feng, Yongmei ^a   Claps, Giuseppina ^a   Fukuda, Michiko N ^a,d   Perlina, Ally ^a   Donn, Dylan ^a   Jilaveanu, Lucia ^b   Kluger, Harriet ^b   Freeze, Hudson H ^a   Ronai, Ze'ev A ^a,c  

^a BURNHAM INSTITUTE   (United States)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c H LEE MOFFITT CANCER CENTER AND RESEARCH INSTITUTE   (United States)

^d NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY AIST   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 2; CELL PROTEIN; CELL SURFACE PROTEIN; FUCOKINASE; FUCOSE; GLYCAN; GLYCOCONJUGATE; GUANOSINE DIPHOSPHATE; PROTEIN KINASE C EPSILON; UNCLASSIFIED DRUG; ATF2 PROTEIN, HUMAN; ATF2 PROTEIN, MOUSE; PHOSPHOTRANSFERASE; TUMOR PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER GROWTH; CANCER PROGNOSIS; CANCER STAGING; CANCER SURVIVAL; CELL ADHESION; CELL MIGRATION; CELL MOTILITY; CONTROLLED STUDY; DIET SUPPLEMENTATION; ENZYME ACTIVATION; FUCOSYLATION; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENETIC MANIPULATION; HUMAN; HUMAN CELL; ISOGRAFT; MAJOR CLINICAL STUDY; MELANOMA METASTASIS; MICROARRAY ANALYSIS; MOUSE; NATURAL KILLER CELL; NONHUMAN; OUTCOME ASSESSMENT; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; TUMOR INVASION; ANIMAL; GENETICS; GLYCOSYLATION; MELANOCYTE; MELANOMA; METABOLISM; METASTASIS; PATHOLOGY; TUMOR CELL LINE;

ACTIVATING TRANSCRIPTION FACTOR 2; ANIMALS; CELL LINE, TUMOR; FUCOSE; GLYCOSYLATION; HUMANS; MELANOCYTES; MELANOMA; MICE; NEOPLASM METASTASIS; NEOPLASM PROTEINS; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR);

EID: 84954321690     PISSN: 19450877     EISSN: 19379145     Source Type: Journal    
DOI: 10.1126/scisignal.aac6479     Document Type: Article

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