-
3
-
-
10344220548
-
Costimulatory B7-H1 in renal cell carcinoma patients: Indicator of tumor aggressiveness and potential therapeutic target
-
Thompson RH, Gillett MD, Cheville JC, Lohse CM, Dong H, Webster WS, et al. Costimulatory B7-H1 in renal cell carcinoma patients: indicator of tumor aggressiveness and potential therapeutic target. Proc Natl Acad Sci U S A 2004;101:17174-9.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 17174-17179
-
-
Thompson, R.H.1
Gillett, M.D.2
Cheville, J.C.3
Lohse, C.M.4
Dong, H.5
Webster, W.S.6
-
4
-
-
34247113727
-
PD-L1 (B7-H1) expression by urothelial carcinoma of the bladder and BCGinduced granulomata: Associations with localized stage progression
-
Inman BA, Sebo TJ, Frigola X, Dong H, Bergstralh EJ, Frank I, et al. PD-L1 (B7-H1) expression by urothelial carcinoma of the bladder and BCGinduced granulomata: Associations with localized stage progression. Cancer 2007;109:1499-505.
-
(2007)
Cancer
, vol.109
, pp. 1499-1505
-
-
Inman, B.A.1
Sebo, T.J.2
Frigola, X.3
Dong, H.4
Bergstralh, E.J.5
Frank, I.6
-
5
-
-
33847611968
-
Programmed cell death 1 ligand 1 and tumor-infiltrating CD8 T lymphocytes are prognostic factors of human ovarian cancer
-
Hamanishi J, Mandai M, Iwasaki M, Okazaki T, Tanaka Y, Yamaguchi K, et al. Programmed cell death 1 ligand 1 and tumor-infiltrating CD8 T lymphocytes are prognostic factors of human ovarian cancer. Proc Natl Acad Sci U S A 2007;104:3360-65.
-
(2007)
Proc Natl Acad Sci U S a
, vol.104
, pp. 3360-3365
-
-
Hamanishi, J.1
Mandai, M.2
Iwasaki, M.3
Okazaki, T.4
Tanaka, Y.5
Yamaguchi, K.6
-
6
-
-
34547098581
-
Expression of B7-H1 in breast cancer patients is strongly associated with high proliferative Ki-67-expressing tumor cells
-
Ghebeh H, Tulbah A, Mohammed S, Elkum N, Bin Amer SM, Al-Tweigeri T, et al. Expression of B7-H1 in breast cancer patients is strongly associated with high proliferative Ki-67-expressing tumor cells. Int J Cancer 2007;121:751-8.
-
(2007)
Int J Cancer
, vol.121
, pp. 751-758
-
-
Ghebeh, H.1
Tulbah, A.2
Mohammed, S.3
Elkum, N.4
Bin, A.S.M.5
Al-Tweigeri, T.6
-
7
-
-
79955518331
-
Overall survival and PD-L1 expression in metastasized malignant melanoma
-
Gadiot J, Hooijkaas AI, Kaiser AD, van Tinteren, H, van Boven, H, Blank C. Overall survival and PD-L1 expression in metastasized malignant melanoma. Cancer 2011;117:2192-201.
-
(2011)
Cancer
, vol.117
, pp. 2192-2201
-
-
Gadiot, J.1
Hooijkaas, A.I.2
Kaiser, A.D.3
Blank, C.4
Van Tinteren, H.5
Van Boven, H.6
-
8
-
-
77950283280
-
Tumor cell expression of programmed cell death-1 ligand 1 is a prognostic factor for malignant melanoma
-
Hino R, Kabashima K, Kato Y, Yagi H, Nakamura M, Honjo T, et al. Tumor cell expression of programmed cell death-1 ligand 1 is a prognostic factor for malignant melanoma. Cancer 2010;116:1757-66.
-
(2010)
Cancer
, vol.116
, pp. 1757-1766
-
-
Hino, R.1
Kabashima, K.2
Kato, Y.3
Yagi, H.4
Nakamura, M.5
Honjo, T.6
-
9
-
-
84879866976
-
PD-L1 expression is characteristic of a subset of aggressive B-cell lymphomas and virus-associated malignancies
-
Chen BJ, Chapuy B, Ouyang J, Sun HH, Roemer MG, Xu ML, et al. PD-L1 expression is characteristic of a subset of aggressive B-cell lymphomas and virus-associated malignancies. Clin Cancer Res 2013;19: 3462-73.
-
(2013)
Clin Cancer Res
, vol.19
, pp. 3462-3473
-
-
Chen, B.J.1
Chapuy, B.2
Ouyang, J.3
Sun, H.H.4
Roemer, M.G.5
Xu, M.L.6
-
10
-
-
34848900497
-
Programmed death-1 blockade enhances expansion and functional capacity of human melanoma antigen-specific CTLs
-
Wong RM, Scotland RR, Lau RL, Wang C, Korman AJ, Kast WM, et al. Programmed death-1 blockade enhances expansion and functional capacity of human melanoma antigen-specific CTLs. Int Immunol 2007; 19:1223-34.
-
(2007)
Int Immunol
, vol.19
, pp. 1223-1234
-
-
Wong, R.M.1
Scotland, R.R.2
Lau, R.L.3
Wang, C.4
Korman, A.J.5
Kast, W.M.6
-
11
-
-
69749106159
-
PD1 blockade reverses the suppression of melanoma antigen-specific CTL by CD4 CD25(Hi) regulatory T cells
-
Wang W, Lau R, Yu D, Zhu W, Korman A, Weber J. PD1 blockade reverses the suppression of melanoma antigen-specific CTL by CD4 CD25(Hi) regulatory T cells. Int Immunol 2009;21:1065-77.
-
(2009)
Int Immunol
, vol.21
, pp. 1065-1077
-
-
Wang, W.1
Lau, R.2
Yu, D.3
Zhu, W.4
Korman, A.5
Weber, J.6
-
12
-
-
77954899030
-
Phase I study of single-agent anti-programmed death-1 (MDX-1106) in refractory solid tumors: Safety, clinical activity, pharmacodynamics, and immunologic correlates
-
Brahmer JR, Drake CG, Wollner I, Powderly JD, Picus J, Sharfman WH, et al. Phase I study of single-agent anti-programmed death-1 (MDX-1106) in refractory solid tumors: safety, clinical activity, pharmacodynamics, and immunologic correlates. J Clin Oncol 2010;28:3167-75.
-
(2010)
J Clin Oncol
, vol.28
, pp. 3167-3175
-
-
Brahmer, J.R.1
Drake, C.G.2
Wollner, I.3
Powderly, J.D.4
Picus, J.5
Sharfman, W.H.6
-
13
-
-
84862859820
-
Safety, activity, and immune correlates of anti-PD-1 antibody in cancer
-
Topalian SL, Hodi FS, Brahmer JR, Gettinger SN, Smith DC, McDermott DF, et al. Safety, activity, and immune correlates of anti-PD-1 antibody in cancer. N Engl J Med 2012;366:2443-54.
-
(2012)
N Engl J Med
, vol.366
, pp. 2443-2454
-
-
Topalian, S.L.1
Hodi, F.S.2
Brahmer, J.R.3
Gettinger, S.N.4
Smith, D.C.5
McDermott, D.F.6
-
14
-
-
84925221855
-
PD-1 blockade with nivolumab in relapsed or refractory Hodgkin's lymphoma
-
Ansell SM, Lesokhin AM, Borrello I, Halwani A, Scott EC, Gutierrez M, et al. PD-1 blockade with nivolumab in relapsed or refractory Hodgkin's lymphoma. N Engl J Med 2015;372:311-9.
-
(2015)
N Engl J Med
, vol.372
, pp. 311-319
-
-
Ansell, S.M.1
Lesokhin, A.M.2
Borrello, I.3
Halwani, A.4
Scott, E.C.5
Gutierrez, M.6
-
15
-
-
84923078390
-
MPDL3280A (anti-PD-L1) treatment leads to clinical activity in metastatic bladder cancer
-
Powles T, Eder JP, Fine GD, Braiteh FS, Loriot Y, Cruz C, et al.MPDL3280A (anti-PD-L1) treatment leads to clinical activity in metastatic bladder cancer. Nature 2014;515:558-62.
-
(2014)
Nature
, vol.515
, pp. 558-562
-
-
Powles, T.1
Eder, J.P.2
Fine, G.D.3
Braiteh, F.S.4
Loriot, Y.5
Cruz, C.6
-
16
-
-
84920956735
-
Predictive correlates of response to the anti-PD-L1 antibodyMPDL3280A in cancer patients
-
Herbst RS, Soria JC, Kowanetz M, Fine GD, Hamid O, Gordon MS, et al. Predictive correlates of response to the anti-PD-L1 antibodyMPDL3280A in cancer patients. Nature 2014;515:563-7.
-
(2014)
Nature
, vol.515
, pp. 563-567
-
-
Herbst, R.S.1
Soria, J.C.2
Kowanetz, M.3
Fine, G.D.4
Hamid, O.5
Gordon, M.S.6
-
17
-
-
84950999432
-
Serum levels of soluble programmed death ligand 1 predict treatment response and progression free survival in multiple myeloma
-
Wang L, Wang H, Chen H, Wang WD, Chen XQ, Geng QR, et al. Serum levels of soluble programmed death ligand 1 predict treatment response and progression free survival in multiple myeloma. Oncotarget 2015;6: 41228-36.
-
(2015)
Oncotarget
, vol.6
, pp. 41228-41236
-
-
Wang, L.1
Wang, H.2
Chen, H.3
Wang, W.D.4
Chen, X.Q.5
Geng, Q.R.6
-
18
-
-
79953306651
-
Identification of a soluble form of B7-H1 that retains immunosuppressive activity and is associated with aggressive renal cell carcinoma
-
Frigola X, Inman BA, Lohse CM, Krco CJ, Cheville JC, Thompson RH, et al. Identification of a soluble form of B7-H1 that retains immunosuppressive activity and is associated with aggressive renal cell carcinoma. Clin Cancer Res 2011;17:1915-23.
-
(2011)
Clin Cancer Res
, vol.17
, pp. 1915-1923
-
-
Frigola, X.1
Inman, B.A.2
Lohse, C.M.3
Krco, C.J.4
Cheville, J.C.5
Thompson, R.H.6
-
19
-
-
84907497893
-
High level of soluble programmed cell death ligand 1 in blood impacts overall survival in aggressive diffuse large B-Cell lymphoma: Results from a French multicenter clinical trial
-
Rossille D, GressierM, Damotte D, Maucort-Boulch D, Pangault C, Semana G, et al. High level of soluble programmed cell death ligand 1 in blood impacts overall survival in aggressive diffuse large B-Cell lymphoma: results from a French multicenter clinical trial. Leukemia 2014;28: 2367-75.
-
(2014)
Leukemia
, vol.28
, pp. 2367-2375
-
-
Rossille, D.1
Gressier, M.2
Damotte, D.3
Maucort-Boulch, D.4
Pangault, C.5
Semana, G.6
-
20
-
-
84857194083
-
Soluble B7-H1: Differences in production between dendritic cells and T cells
-
Frigola X, Inman BA, Krco CJ, Liu X, Harrington SM, Bulur PA, et al. Soluble B7-H1: differences in production between dendritic cells and T cells. Immunol Lett 2012;142:78-82.
-
(2012)
Immunol Lett
, vol.142
, pp. 78-82
-
-
Frigola, X.1
Inman, B.A.2
Krco, C.J.3
Liu, X.4
Harrington, S.M.5
Bulur, P.A.6
-
21
-
-
16444367280
-
Identification of a novel splice variant of human PDL1 mRNA encoding an isoform-lacking Igv-like domain
-
He XH, Xu LH, Liu Y. Identification of a novel splice variant of human PDL1 mRNA encoding an isoform-lacking Igv-like domain. Acta pharmacologica Sinica 2005;26:462-8.
-
(2005)
Acta Pharmacologica Sinica
, vol.26
, pp. 462-468
-
-
He, X.H.1
Xu, L.H.2
Liu, Y.3
-
22
-
-
84964313298
-
Bevacizumab plus ipilimumab in patients with metastatic melanoma
-
Hodi FS, Lawrence D, Lezcano C, Wu X, Zhou J, Sasada T, et al. Bevacizumab plus ipilimumab in patients with metastatic melanoma. Cancer Immunol Res 2014;2:632-42.
-
(2014)
Cancer Immunol Res
, vol.2
, pp. 632-642
-
-
Hodi, F.S.1
Lawrence, D.2
Lezcano, C.3
Wu, X.4
Zhou, J.5
Sasada, T.6
-
23
-
-
84908664534
-
Ipilimumab plus sargramostim vs ipilimumab alone for treatment of metastatic melanoma: A randomized clinical trial
-
Hodi FS, Lee S, McDermott DF, Rao UN, Butterfield LH, Tarhini AA, et al. Ipilimumab plus sargramostim vs ipilimumab alone for treatment of metastatic melanoma: A randomized clinical trial. JAMA 2014;312: 1744-53.
-
(2014)
JAMA
, vol.312
, pp. 1744-1753
-
-
Hodi, F.S.1
Lee, S.2
McDermott, D.F.3
Rao, U.N.4
Butterfield, L.H.5
Tarhini, A.A.6
-
24
-
-
0032626964
-
An application of changepoint methods in studying the effect of age on survival in breast cancer
-
Contal C, O'Quigley J. An application of changepoint methods in studying the effect of age on survival in breast cancer. Comput Stat Data Analys 1999;30:253-70.
-
(1999)
Comput Stat Data Analys
, vol.30
, pp. 253-270
-
-
Contal, C.1
O'Quigley, J.2
-
25
-
-
0037452924
-
Melanoma inhibitor of apoptosis protein (ML-IAP) is a target for immune-mediated tumor destruction
-
Schmollinger JC, Vonderheide RH, Hoar KM, Maecker B, Schultze JL, Hodi FS, et al. Melanoma inhibitor of apoptosis protein (ML-IAP) is a target for immune-mediated tumor destruction. Proc Natl Acad Sci U S A 2003;100:3398-403.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 3398-3403
-
-
Schmollinger, J.C.1
Vonderheide, R.H.2
Hoar, K.M.3
Maecker, B.4
Schultze, J.L.5
Hodi, F.S.6
-
26
-
-
83455254767
-
RAF inhibitor resistance is mediated by dimerization of aberrantly spliced BRAF(V600E)
-
Poulikakos PI, Persaud Y, Janakiraman M, Kong X, Ng C, Moriceau G, et al. RAF inhibitor resistance is mediated by dimerization of aberrantly spliced BRAF(V600E). Nature 2011;480:387-90.
-
(2011)
Nature
, vol.480
, pp. 387-390
-
-
Poulikakos, P.I.1
Persaud, Y.2
Janakiraman, M.3
Kong, X.4
Ng, C.5
Moriceau, G.6
-
27
-
-
84928917822
-
Pooled analysis of long-term survival data from phase II and phase III trials of ipilimumab in unresectable or metastatic melanoma
-
Schadendorf D, Hodi FS, Robert C, Weber JS, Margolin K, Hamid O, et al. Pooled analysis of long-term survival data from phase II and phase iii trials of ipilimumab in unresectable or metastatic melanoma. J Clin Oncol 2015;33:1889-94.
-
(2015)
J Clin Oncol
, vol.33
, pp. 1889-1894
-
-
Schadendorf, D.1
Hodi, F.S.2
Robert, C.3
Weber, J.S.4
Margolin, K.5
Hamid, O.6
-
28
-
-
84942430653
-
Combined nivolumab and ipilimumab or monotherapy in untreated melanoma
-
Larkin J, Hodi FS, Wolchok JD. Combined nivolumab and ipilimumab or monotherapy in untreated melanoma.NEngl JMed 2015;373:1270-71.
-
(2015)
NEngl JMed
, vol.373
, pp. 1270-1271
-
-
Larkin, J.1
Hodi, F.S.2
Wolchok, J.D.3
-
29
-
-
7444220147
-
Aberrant and alternative splicing in cancer
-
Venables JP.Aberrant and alternative splicing in cancer. Cancer Res 2004;64:7647-54.
-
(2004)
Cancer Res
, vol.64
, pp. 7647-7654
-
-
Venables, J.P.1
-
30
-
-
0034705021
-
Secreted and membrane attractin result from alternative splicing of the human ATRN gene
-
Tang W, Gunn TM, McLaughlin DF, Barsh GS, Schlossman SF, Duke-Cohan JS. Secreted and membrane attractin result from alternative splicing of the human ATRN gene. Proc Natl Acad Sci U S A 2000;97:6025-30.
-
(2000)
Proc Natl Acad Sci U S a
, vol.97
, pp. 6025-6030
-
-
Tang, W.1
Gunn, T.M.2
McLaughlin, D.F.3
Barsh, G.S.4
Schlossman, S.F.5
Duke-Cohan, J.S.6
-
31
-
-
0024246094
-
Alternative splicing generates a secreted form of N-CAM in muscle and brain
-
Gower HJ, Barton CH, Elsom VL, Thompson J, Moore SE, Dickson G, et al. Alternative splicing generates a secreted form of N-CAM in muscle and brain. Cell 1988;55:955-64.
-
(1988)
Cell
, vol.55
, pp. 955-964
-
-
Gower, H.J.1
Barton, C.H.2
Elsom, V.L.3
Thompson, J.4
Moore, S.E.5
Dickson, G.6
-
32
-
-
77954003833
-
An alternatively spliced CXCL16 isoform expressed by dendritic cells is a secreted chemoattractant for CXCR6 cells
-
van der Voort, R, Verweij V, de Witte, TM, Lasonder E, Adema GJ, Dolstra H. An alternatively spliced CXCL16 isoform expressed by dendritic cells is a secreted chemoattractant for CXCR6 cells. J Leukoc Biol 2010;87: 1029-39.
-
(2010)
J Leukoc Biol
, vol.87
, pp. 1029-1039
-
-
Verweij, V.1
Lasonder, E.2
Adema, G.J.3
Dolstra, H.4
Van Der Voort, R.5
De Witte, T.M.6
-
33
-
-
0032932822
-
Insulin receptor isoform A, a newly recognized, high-affinity insulin-like growth factor II receptor in fetal and cancer cells
-
Frasca F, Pandini G, Scalia P, Sciacca L, Mineo R, Costantino A, et al. Insulin receptor isoform A, a newly recognized, high-affinity insulin-like growth factor II receptor in fetal and cancer cells. Mol Cell Biol 1999;19:3278-88.
-
(1999)
Mol Cell Biol
, vol.19
, pp. 3278-3288
-
-
Frasca, F.1
Pandini, G.2
Scalia, P.3
Sciacca, L.4
Mineo, R.5
Costantino, A.6
-
34
-
-
0036148531
-
A novel autocrine loop involving IGF-II and the insulin receptor isoform-A stimulates growth of thyroid cancer
-
Vella V, Pandini G, Sciacca L, Mineo R, Vigneri R, Pezzino V, et al. A novel autocrine loop involving IGF-II and the insulin receptor isoform-A stimulates growth of thyroid cancer. J Clin Endocrinol Metab 2002;87:245-54.
-
(2002)
J Clin Endocrinol Metab
, vol.87
, pp. 245-254
-
-
Vella, V.1
Pandini, G.2
Sciacca, L.3
Mineo, R.4
Vigneri, R.5
Pezzino, V.6
-
35
-
-
79952284127
-
Hallmarks of cancer: The next generation
-
Hanahan D, Weinberg RA. Hallmarks of cancer: The next generation. Cell 2011;144:646-74.
-
(2011)
Cell
, vol.144
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
36
-
-
0347302952
-
Cytokines in cancer pathogenesis and cancer therapy
-
Dranoff G.Cytokines in cancer pathogenesis and cancer therapy. Nat Rev Cancer 2004;4:11-22.
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 11-22
-
-
Dranoff, G.1
-
37
-
-
0037180757
-
Inflammation and cancer
-
Coussens LM, Werb Z. Inflammation and cancer. Nature 2002;420:860-67.
-
(2002)
Nature
, vol.420
, pp. 860-867
-
-
Coussens, L.M.1
Werb, Z.2
-
39
-
-
18544380239
-
Tumor-associated B7-H1 promotes T-cell apoptosis: A potential mechanism of immune evasion
-
Dong H, Strome SE, Salomao DR, Tamura H, Hirano F, Flies DB, et al. Tumor-associated B7-H1 promotes T-cell apoptosis: A potential mechanism of immune evasion. Nat Med 2002;8:793-800.
-
(2002)
Nat Med
, vol.8
, pp. 793-800
-
-
Dong, H.1
Strome, S.E.2
Salomao, D.R.3
Tamura, H.4
Hirano, F.5
Flies, D.B.6
-
40
-
-
84875171283
-
PD-L1 on tumor cells is induced in ascites and promotes peritoneal dissemination of ovarian cancer through CTL dysfunction
-
Abiko K, Mandai M, Hamanishi J, Yoshioka Y, Matsumura N, Baba T, et al. PD-L1 on tumor cells is induced in ascites and promotes peritoneal dissemination of ovarian cancer through CTL dysfunction. Clin Cancer Res 2013;19:1363-74.
-
(2013)
Clin Cancer Res
, vol.19
, pp. 1363-1374
-
-
Abiko, K.1
Mandai, M.2
Hamanishi, J.3
Yoshioka, Y.4
Matsumura, N.5
Baba, T.6
-
41
-
-
31444451661
-
Interferon regulatory factor-1 is prerequisite to the constitutive expression and IFN-gammainduced upregulation of B7-H1 (CD274)
-
Lee SJ, Jang BC, Lee SW, Yang YI, Suh SI, Park YM, et al. Interferon regulatory factor-1 is prerequisite to the constitutive expression and IFN-gammainduced upregulation of B7-H1 (CD274). FEBS Lett 2006;580:755-62.
-
(2006)
FEBS Lett
, vol.580
, pp. 755-762
-
-
Lee, S.J.1
Jang, B.C.2
Lee, S.W.3
Yang, Y.I.4
Suh, S.I.5
Park, Y.M.6
-
42
-
-
34347400169
-
Plasma cells from multiple myeloma patients express B7-H1 (PD-L1) and increase expression after stimulation with IFN-{gamma} and TLR ligands via a MyD88-, TRAF6-, and MEK-dependent pathway
-
Liu J, Hamrouni A, Wolowiec D, Coiteux V, Kuliczkowski K, Hetuin D, et al. Plasma cells from multiple myeloma patients express B7-H1 (PD-L1) and increase expression after stimulation with IFN-{gamma} and TLR ligands via a MyD88-, TRAF6-, and MEK-dependent pathway. Blood 2007;110: 296-304.
-
(2007)
Blood
, vol.110
, pp. 296-304
-
-
Liu, J.1
Hamrouni, A.2
Wolowiec, D.3
Coiteux, V.4
Kuliczkowski, K.5
Hetuin, D.6
-
43
-
-
84883863501
-
Upregulation of PD-L1, IDO, and T(regs) in the melanoma tumor microenvironment is driven by CD8() T cells
-
200ra116
-
Spranger S, Spaapen RM, Zha Y, Williams J, Meng Y, Ha TT, et al. Upregulation of PD-L1, IDO, and T(regs) in the melanoma tumor microenvironment is driven by CD8() T cells. Sci TranslatMed 2013;5:200ra116.
-
(2013)
Sci TranslatMed
, pp. 5
-
-
Spranger, S.1
Spaapen, R.M.2
Zha, Y.3
Williams, J.4
Meng, Y.5
Ha, T.T.6
-
44
-
-
84920956732
-
PD-1 blockade induces responses by inhibiting adaptive immune resistance
-
Tumeh PC, Harview CL, Yearley JH, Shintaku IP, Taylor EJ, Robert L, et al. PD-1 blockade induces responses by inhibiting adaptive immune resistance. Nature 2014;515:568-71.
-
(2014)
Nature
, vol.515
, pp. 568-571
-
-
Tumeh, P.C.1
Harview, C.L.2
Yearley, J.H.3
Shintaku, I.P.4
Taylor, E.J.5
Robert, L.6
-
45
-
-
0038273853
-
Blockade of B7-H1 improves myeloid dendritic cell-mediated antitumor immunity
-
Curiel TJ, Wei S, Dong H, Alvarez X, Cheng P, Mottram P, et al. Blockade of B7-H1 improves myeloid dendritic cell-mediated antitumor immunity. Nat Med 2003;9:562-7.
-
(2003)
Nat Med
, vol.9
, pp. 562-567
-
-
Curiel, T.J.1
Wei, S.2
Dong, H.3
Alvarez, X.4
Cheng, P.5
Mottram, P.6
|