Adaptive evolution of the lactose utilization network in experimentally evolved populations of Escherichia coli

PLoS Genetics

Volumn 8, Issue 1, 2012, Pages

  Quan, Selwyn ^a   Ray, J Christian J ^b   Kwota, Zakari ^c   Duong, Trang ^c   Balázsi, Gábor ^b   Cooper, Tim F ^c   Monds, Russell D ^a  

^a STANFORD UNIVERSITY   (United States)

^b UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^c University of Houston   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; LACTOSE; ESCHERICHIA COLI PROTEIN; LAC REPRESSOR; LACI PROTEIN, E COLI;

ARTICLE; BACTERIAL MUTATION; BINDING SITE; CARBOHYDRATE METABOLISM; CONTROLLED STUDY; ENVIRONMENTAL CHANGE; ESCHERICHIA COLI; EVOLUTIONARY ADAPTATION; GENE DELETION; GENE EXPRESSION REGULATION; GENE FREQUENCY; GENE INTERACTION; GENE REGULATORY NETWORK; GENE SEQUENCE; GENETIC ASSOCIATION; GENETIC SELECTION; GENETIC VARIABILITY; LACTOSE OPERON; MICROBIAL COMMUNITY; MOLECULAR CLONING; MOLECULAR RECOGNITION; NONHUMAN; PHENOTYPIC VARIATION; PROMOTER REGION; ADAPTATION; DIRECTED MOLECULAR EVOLUTION; ENVIRONMENT; GENETICS; METABOLISM; MUTATION; REPRODUCTIVE FITNESS;

ESCHERICHIA COLI;

ADAPTATION, PHYSIOLOGICAL; DIRECTED MOLECULAR EVOLUTION; ENVIRONMENT; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; GENE EXPRESSION REGULATION, BACTERIAL; GENETIC FITNESS; LAC OPERON; LAC REPRESSORS; LACTOSE; METABOLIC NETWORKS AND PATHWAYS; MUTATION; PROMOTER REGIONS, GENETIC;

EID: 84857467293     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1002444     Document Type: Article

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