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Volumn 18, Issue 6, 2017, Pages

Micro-RNAs as potential predictors of response to breast cancer systemic therapy: Future clinical implications

Author keywords

Breast cancer; MiRNAs; Response to systemic therapy

Indexed keywords

AROMATASE INHIBITOR; CAPECITABINE; CISPLATIN; DOCETAXEL; DOXORUBICIN; EPIRUBICIN; GEMCITABINE; LAPATINIB; LETROZOLE; MICRORNA; PACLITAXEL; SELECTIVE ESTROGEN RECEPTOR MODULATOR; TAMOXIFEN; TRASTUZUMAB; TUMOR MARKER; VINORELBINE TARTRATE;

EID: 85020425580     PISSN: 16616596     EISSN: 14220067     Source Type: Journal    
DOI: 10.3390/ijms18061182     Document Type: Review
Times cited : (44)

References (113)
  • 4
    • 84863715487 scopus 로고    scopus 로고
    • Chemotherapy-resistant metastatic breast cancer
    • Marquette, C., Nabell, L. Chemotherapy-resistant metastatic breast cancer. Curr. Treat. Opt. Oncol. 2012, 13, 263-275.
    • (2012) Curr. Treat. Opt. Oncol , vol.13 , pp. 263-275
    • Marquette, C.1    Nabell, L.2
  • 5
    • 0037009364 scopus 로고    scopus 로고
    • MicroRNA maturation: Stepwise processing and subcellular localization
    • Lee, Y., Jeon, K., Lee, J.-T., Kim, S., Kim, V.N. MicroRNA maturation: Stepwise processing and subcellular localization. EMBO J. 2002, 21, 4663-4670.
    • (2002) EMBO J , vol.21 , pp. 4663-4670
    • Lee, Y.1    Jeon, K.2    Lee, J.-T.3    Kim, S.4    Kim, V.N.5
  • 6
    • 4444230672 scopus 로고    scopus 로고
    • Structural requirements for pre-microRNA binding and nuclear export by Exportin 5
    • Zeng, Y., Cullen, B.R. Structural requirements for pre-microRNA binding and nuclear export by Exportin 5. Nucleic Acids Res. 2004, 32, 4776-4785.
    • (2004) Nucleic Acids Res , vol.32 , pp. 4776-4785
    • Zeng, Y.1    Cullen, B.R.2
  • 8
    • 84931572130 scopus 로고    scopus 로고
    • Towards a molecular understanding of microRNA-mediated gene silencing
    • Jonas, S., Izaurralde, E. Towards a molecular understanding of microRNA-mediated gene silencing. Nat. Rev. Genet. 2015, 16, 421-433.
    • (2015) Nat. Rev. Genet , vol.16 , pp. 421-433
    • Jonas, S.1    Izaurralde, E.2
  • 10
    • 77955591555 scopus 로고    scopus 로고
    • MicroRNAs and their target gene networks in breast cancer
    • O’Day, E., Lal, A. MicroRNAs and their target gene networks in breast cancer. Breast Cancer Res. 2010, 12, 201.
    • (2010) Breast Cancer Res , vol.12 , pp. 201
    • O’Day, E.1    Lal, A.2
  • 12
    • 0034175066 scopus 로고    scopus 로고
    • Taxanes for breast cancer: An evidence-based review of randomized phase II and phase III trials
    • Sparano, J.A. Taxanes for breast cancer: An evidence-based review of randomized phase II and phase III trials. Clin. Breast Cancer 2000.
    • (2000) Clin. Breast Cancer
    • Sparano, J.A.1
  • 13
    • 2942562025 scopus 로고    scopus 로고
    • Docetaxel and paclitaxel in the treatment of breast cancer: A review of clinical experience
    • Crown, J., O’Leary, M., Ooi, W.-S. Docetaxel and paclitaxel in the treatment of breast cancer: A review of clinical experience. Oncologist 2004, 9, 24-32.
    • (2004) Oncologist , vol.9 , pp. 24-32
    • Crown, J.1    O’Leary, M.2    Ooi, W.-S.3
  • 15
    • 84872256346 scopus 로고    scopus 로고
    • Paclitaxel-based versus docetaxel-based regimens in metastatic breast cancer: A systematic review and meta-analysis of randomized controlled trials
    • Qi, W.-X., Shen, Z., Lin, F., Sun, Y., Min, D., Tang, L.-N., He, A.-N., Yao, Y. Paclitaxel-based versus docetaxel-based regimens in metastatic breast cancer: A systematic review and meta-analysis of randomized controlled trials. Curr. Med. Res. Opin. 2013, 29, 117-125.
    • (2013) Curr. Med. Res. Opin , vol.29 , pp. 117-125
    • Qi, W.-X.1    Shen, Z.2    Lin, F.3    Sun, Y.4    Min, D.5    Tang, L.-N.6    He, A.-N.7    Yao, Y.8
  • 16
    • 84875313377 scopus 로고    scopus 로고
    • Randomised phase III open-label trial of first-line treatment with gemcitabine in association with docetaxel or paclitaxel in women with metastatic breast cancer: A comparison of different schedules and treatments
    • Del Mastro, L., Fabi, A., Mansutti, M., de Laurentiis, M., Durando, A., Merlo, D.F., Bruzzi, P., La Torre, I., Ceccarelli, M., Kazeem, G., et al. Randomised phase III open-label trial of first-line treatment with gemcitabine in association with docetaxel or paclitaxel in women with metastatic breast cancer: A comparison of different schedules and treatments. BMC Cancer 2013, 13, 164.
    • (2013) BMC Cancer , vol.13 , pp. 164
    • Del Mastro, L.1    Fabi, A.2    Mansutti, M.3    De Laurentiis, M.4    Durando, A.5    Merlo, D.F.6    Bruzzi, P.7    La Torre, I.8    Ceccarelli, M.9    Kazeem, G.10
  • 17
    • 84857038574 scopus 로고    scopus 로고
    • Consorzio Interuniversitario Nazionale per la Bio-Oncologia (CINBO) Meta-analysis of phase III trials of docetaxel alone or in combination with chemotherapy in metastatic breast cancer
    • Belfiglio, M., Fanizza, C., Tinari, N., Ficorella, C., Iacobelli, S., Natoli, C. Consorzio Interuniversitario Nazionale per la Bio-Oncologia (CINBO) Meta-analysis of phase III trials of docetaxel alone or in combination with chemotherapy in metastatic breast cancer. J. Cancer Res. Clin. Oncol. 2012, 138, 221-229.
    • (2012) J. Cancer Res. Clin. Oncol , vol.138 , pp. 221-229
    • Belfiglio, M.1    Fanizza, C.2    Tinari, N.3    Ficorella, C.4    Iacobelli, S.5    Natoli, C.6
  • 19
    • 84928606617 scopus 로고    scopus 로고
    • Wound healing and cancer stem cells: Inflammation as a driver of treatment resistance in breast cancer
    • Arnold, K.M., Opdenaker, L.M., Flynn, D., Sims-Mourtada, J. Wound healing and cancer stem cells: Inflammation as a driver of treatment resistance in breast cancer. Cancer Growth Metastasis 2015, 8, 1-13.
    • (2015) Cancer Growth Metastasis , vol.8 , pp. 1-13
    • Arnold, K.M.1    Opdenaker, L.M.2    Flynn, D.3    Sims-Mourtada, J.4
  • 20
    • 84863613073 scopus 로고    scopus 로고
    • Lin28 mediates paclitaxel resistance by modulating p21, Rb and Let-7a miRNA in breast cancer cells
    • Lv, K., Liu, L., Wang, L., Yu, J., Liu, X., Cheng, Y., Dong, M., Teng, R., Wu, L., Fu, P., et al. Lin28 mediates paclitaxel resistance by modulating p21, Rb and Let-7a miRNA in breast cancer cells. PLoS ONE 2012, 7, e40008.
    • (2012) Plos ONE , vol.7
    • Lv, K.1    Liu, L.2    Wang, L.3    Yu, J.4    Liu, X.5    Cheng, Y.6    Dong, M.7    Teng, R.8    Wu, L.9    Fu, P.10
  • 21
    • 77954378366 scopus 로고    scopus 로고
    • MicroRNA-125b confers the resistance of breast cancer cells to paclitaxel through suppression of pro-apoptotic Bcl-2 antagonist killer 1 (Bak1) expression
    • Zhou, M., Liu, Z., Zhao, Y., Ding, Y., Liu, H., Xi, Y., Xiong, W., Li, G., Lu, J., Fodstad, O., et al. MicroRNA-125b confers the resistance of breast cancer cells to paclitaxel through suppression of pro-apoptotic Bcl-2 antagonist killer 1 (Bak1) expression. J. Biol. Chem. 2010, 285, 21496-21507.
    • (2010) J. Biol. Chem , vol.285 , pp. 21496-21507
    • Zhou, M.1    Liu, Z.2    Zhao, Y.3    Ding, Y.4    Liu, H.5    Xi, Y.6    Xiong, W.7    Li, G.8    Lu, J.9    Fodstad, O.10
  • 23
    • 84946568130 scopus 로고    scopus 로고
    • Influence of miR-451 on Drug Resistances of Paclitaxel-Resistant Breast Cancer Cell Line
    • Gu, X., Li, J.-Y., Guo, J., Li, P.-S., Zhang, W.-H. Influence of miR-451 on Drug Resistances of Paclitaxel-Resistant Breast Cancer Cell Line. Med. Sci. Monit. 2015, 21, 3291-3297.
    • (2015) Med. Sci. Monit , vol.21 , pp. 3291-3297
    • Gu, X.1    Li, J.-Y.2    Guo, J.3    Li, P.-S.4    Zhang, W.-H.5
  • 24
    • 84958092652 scopus 로고    scopus 로고
    • MicroRNA 100 sensitizes luminal A breast cancer cells to paclitaxel treatment in part by targeting mTOR
    • Zhang, B., Zhao, R., He, Y., Fu, X., Fu, L., Zhu, Z., Fu, L., Dong, J.-T. MicroRNA 100 sensitizes luminal A breast cancer cells to paclitaxel treatment in part by targeting mTOR. Oncotarget 2016, 7, 5702-5714.
    • (2016) Oncotarget , vol.7 , pp. 5702-5714
    • Zhang, B.1    Zhao, R.2    He, Y.3    Fu, X.4    Fu, L.5    Zhu, Z.6    Fu, L.7    Dong, J.-T.8
  • 25
    • 85007188444 scopus 로고    scopus 로고
    • MiR-18a upregulation decreases Dicer expression and confers paclitaxel resistance in triple negative breast cancer
    • Sha, L.-Y., Zhang, Y., Wang, W., Sui, X., Liu, S.-K., Wang, T., Zhang, H. miR-18a upregulation decreases Dicer expression and confers paclitaxel resistance in triple negative breast cancer. Eur. Rev. Med. Pharmacol. Sci. 2016, 20, 2201-2208.
    • (2016) Eur. Rev. Med. Pharmacol. Sci , vol.20 , pp. 2201-2208
    • Sha, L.-Y.1    Zhang, Y.2    Wang, W.3    Sui, X.4    Liu, S.-K.5    Wang, T.6    Zhang, H.7
  • 26
    • 51749088101 scopus 로고    scopus 로고
    • Let-7a microRNA suppresses therapeutics-induced cancer cell death by targeting caspase-3
    • Tsang, W.P., Kwok, T.T. Let-7a microRNA suppresses therapeutics-induced cancer cell death by targeting caspase-3. Apoptosis 2008, 13, 1215-1222.
    • (2008) Apoptosis , vol.13 , pp. 1215-1222
    • Tsang, W.P.1    Kwok, T.T.2
  • 27
    • 84912142413 scopus 로고    scopus 로고
    • Decrease of let-7f in low-dose metronomic Paclitaxel chemotherapy contributed to upregulation of thrombospondin-1 in breast cancer
    • Tao, W.-Y., Liang, X.-S., Liu, Y., Wang, C.-Y., Pang, D. Decrease of let-7f in low-dose metronomic Paclitaxel chemotherapy contributed to upregulation of thrombospondin-1 in breast cancer. Int. J. Biol. Sci. 2015, 11, 48-58.
    • (2015) Int. J. Biol. Sci , vol.11 , pp. 48-58
    • Tao, W.-Y.1    Liang, X.-S.2    Liu, Y.3    Wang, C.-Y.4    Pang, D.5
  • 28
    • 84940208320 scopus 로고    scopus 로고
    • MicroRNA-101 inhibits cell progression and increases paclitaxel sensitivity by suppressing MCL-1 expression in human triple-negative breast cancer
    • Liu, X., Tang, H., Chen, J., Song, C., Yang, L., Liu, P., Wang, N., Xie, X., Lin, X., Xie, X. MicroRNA-101 inhibits cell progression and increases paclitaxel sensitivity by suppressing MCL-1 expression in human triple-negative breast cancer. Oncotarget 2015, 6, 20070-20083.
    • (2015) Oncotarget , vol.6 , pp. 20070-20083
    • Liu, X.1    Tang, H.2    Chen, J.3    Song, C.4    Yang, L.5    Liu, P.6    Wang, N.7    Xie, X.8    Lin, X.9    Xie, X.10
  • 29
    • 24044477528 scopus 로고    scopus 로고
    • Docetaxel in the treatment of breast cancer: Current experience and future prospects
    • Nabholtz, J.-M., Gligorov, J. Docetaxel in the treatment of breast cancer: Current experience and future prospects. Expert Rev. Anticancer Ther. 2005, 5, 613-633.
    • (2005) Expert Rev. Anticancer Ther , vol.5 , pp. 613-633
    • Nabholtz, J.-M.1    Gligorov, J.2
  • 30
    • 84927153473 scopus 로고    scopus 로고
    • MiR-141 confers docetaxel chemoresistance of breast cancer cells via regulation of EIF4E expression
    • Yao, Y.-S., Qiu, W.-S., Yao, R.-Y., Zhang, Q., Zhuang, L.-K., Zhou, F., Sun, L.-B., Yue, L. miR-141 confers docetaxel chemoresistance of breast cancer cells via regulation of EIF4E expression. Oncol. Rep. 2015, 33, 2504-2512.
    • (2015) Oncol. Rep , vol.33 , pp. 2504-2512
    • Yao, Y.-S.1    Qiu, W.-S.2    Yao, R.-Y.3    Zhang, Q.4    Zhuang, L.-K.5    Zhou, F.6    Sun, L.-B.7    Yue, L.8
  • 31
    • 84944929730 scopus 로고    scopus 로고
    • MiR-129-3p promotes docetaxel resistance of breast cancer cells via CP110 inhibition. Sci
    • Zhang, Y., Wang, Y., Wei, Y., Li, M., Yu, S., Ye, M., Zhang, H., Chen, S., Liu, W., Zhang, J. miR-129-3p promotes docetaxel resistance of breast cancer cells via CP110 inhibition. Sci. Rep. 2015, 5, 15424.
    • (2015) Rep , vol.5 , pp. 15424
    • Zhang, Y.1    Wang, Y.2    Wei, Y.3    Li, M.4    Yu, S.5    Ye, M.6    Zhang, H.7    Chen, S.8    Liu, W.9    Zhang, J.10
  • 32
    • 84962882030 scopus 로고    scopus 로고
    • MicroRNA-3646 Contributes to Docetaxel Resistance in Human Breast Cancer Cells by GSK-3-/--Catenin Signaling Pathway
    • Zhang, X., Zhong, S., Xu, Y., Yu, D., Ma, T., Chen, L., Zhao, Y., Chen, X., Yang, S., Wu, Y., et al. MicroRNA-3646 Contributes to Docetaxel Resistance in Human Breast Cancer Cells by GSK-3-/--Catenin Signaling Pathway. PLoS ONE 2016, 11, e0153194.
    • (2016) Plos ONE , vol.11
    • Zhang, X.1    Zhong, S.2    Xu, Y.3    Yu, D.4    Ma, T.5    Chen, L.6    Zhao, Y.7    Chen, X.8    Yang, S.9    Wu, Y.10
  • 33
    • 84905059972 scopus 로고    scopus 로고
    • MicroRNA-452 contributes to the docetaxel resistance of breast cancer cells
    • Hu, Q., Chen, W., Zhong, S., Zhang, J., Ma, T., Ji, H., Lv, M., Tang, J., Zhao, J. MicroRNA-452 contributes to the docetaxel resistance of breast cancer cells. Tumour Biol. 2014, 35, 6327-6334.
    • (2014) Tumour Biol , vol.35 , pp. 6327-6334
    • Hu, Q.1    Chen, W.2    Zhong, S.3    Zhang, J.4    Ma, T.5    Ji, H.6    Lv, M.7    Tang, J.8    Zhao, J.9
  • 34
    • 84876543387 scopus 로고    scopus 로고
    • The overexpression of hypomethylated miR-663 induces chemotherapy resistance in human breast cancer cells by targeting heparin sulfate proteoglycan 2 (HSPG2)
    • Hu, H., Li, S., Cui, X., Lv, X., Jiao, Y., Yu, F., Yao, H., Song, E., Chen, Y., Wang, M., et al. The overexpression of hypomethylated miR-663 induces chemotherapy resistance in human breast cancer cells by targeting heparin sulfate proteoglycan 2 (HSPG2). J. Biol. Chem. 2013, 288, 10973-10985.
    • (2013) J. Biol. Chem , vol.288 , pp. 10973-10985
    • Hu, H.1    Li, S.2    Cui, X.3    Lv, X.4    Jiao, Y.5    Yu, F.6    Yao, H.7    Song, E.8    Chen, Y.9    Wang, M.10
  • 35
    • 84856231030 scopus 로고    scopus 로고
    • MiRNA-34a is associated with docetaxel resistance in human breast cancer cells. Breast Cancer Res
    • Kastl, L., Brown, I., Schofield, A.C. miRNA-34a is associated with docetaxel resistance in human breast cancer cells. Breast Cancer Res. Treat. 2012, 131, 445-454.
    • (2012) Treat , vol.131 , pp. 445-454
    • Kastl, L.1    Brown, I.2    Schofield, A.C.3
  • 36
    • 84941314449 scopus 로고    scopus 로고
    • MiR-139-5p inhibits the biological function of breast cancer cells by targeting Notch1 and mediates chemosensitivity to docetaxel
    • Zhang, H., Sun, D.-W., Mao, L., Zhang, J., Jiang, L.-H., Li, J., Wu, Y., Ji, H., Chen, W., Wang, J., et al. miR-139-5p inhibits the biological function of breast cancer cells by targeting Notch1 and mediates chemosensitivity to docetaxel. Biochem. Biophys. Res. Commun. 2015, 465, 702-713.
    • (2015) Biochem. Biophys. Res. Commun , vol.465 , pp. 702-713
    • Zhang, H.1    Sun, D.-W.2    Mao, L.3    Zhang, J.4    Jiang, L.-H.5    Li, J.6    Wu, Y.7    Ji, H.8    Chen, W.9    Wang, J.10
  • 37
    • 84954342231 scopus 로고    scopus 로고
    • MicroRNA-205 increases the sensitivity of docetaxel in breast cancer
    • Cai, Y., Yan, X., Zhang, G., Zhao, W., Jiao, S. MicroRNA-205 increases the sensitivity of docetaxel in breast cancer. Oncol. Lett. 2016, 11, 1105-1109.
    • (2016) Oncol. Lett , vol.11 , pp. 1105-1109
    • Cai, Y.1    Yan, X.2    Zhang, G.3    Zhao, W.4    Jiao, S.5
  • 38
    • 84991686274 scopus 로고    scopus 로고
    • Enforced expression of hsa-miR-125a-3p in breast cancer cells potentiates docetaxel sensitivity via modulation of BRCA1 signaling
    • Xu, X., Lv, Y.-G., Yan, C.-Y., Yi, J., Ling, R. Enforced expression of hsa-miR-125a-3p in breast cancer cells potentiates docetaxel sensitivity via modulation of BRCA1 signaling. Biochem. Biophys. Res. Commun. 2016, 479, 893-900.
    • (2016) Biochem. Biophys. Res. Commun , vol.479 , pp. 893-900
    • Xu, X.1    Lv, Y.-G.2    Yan, C.-Y.3    Yi, J.4    Ling, R.5
  • 39
    • 84884820584 scopus 로고    scopus 로고
    • MiR-222 and miR-29a contribute to the drug-resistance of breast cancer cells
    • Zhong, S., Li, W., Chen, Z., Xu, J., Zhao, J. miR-222 and miR-29a contribute to the drug-resistance of breast cancer cells. Gene 2013, 531, 8-14.
    • (2013) Gene , vol.531 , pp. 8-14
    • Zhong, S.1    Li, W.2    Chen, Z.3    Xu, J.4    Zhao, J.5
  • 40
    • 84922392532 scopus 로고    scopus 로고
    • Exosomes from docetaxel-resistant breast cancer cells alter chemosensitivity by delivering microRNAs
    • Chen, W.-X., Cai, Y.-Q., Lv, M.-M., Chen, L., Zhong, S.-L., Ma, T.-F., Zhao, J.-H., Tang, J.-H. Exosomes from docetaxel-resistant breast cancer cells alter chemosensitivity by delivering microRNAs. Tumour Biol. 2014, 35, 9649-9659.
    • (2014) Tumour Biol , vol.35 , pp. 9649-9659
    • Chen, W.-X.1    Cai, Y.-Q.2    Lv, M.-M.3    Chen, L.4    Zhong, S.-L.5    Ma, T.-F.6    Zhao, J.-H.7    Tang, J.-H.8
  • 42
    • 0029618368 scopus 로고
    • Steroid hormone receptors: Many actors in search of a plot
    • Beato, M., Herrlich, P., Schütz, G. Steroid hormone receptors: Many actors in search of a plot. Cell 1995, 83, 851-857.
    • (1995) Cell , vol.83 , pp. 851-857
    • Beato, M.1    Herrlich, P.2    Schütz, G.3
  • 43
    • 0028283503 scopus 로고
    • Molecular mechanisms of action of steroid/thyroid receptor superfamily members
    • Tsai, M.J., O’Malley, B.W. Molecular mechanisms of action of steroid/thyroid receptor superfamily members. Annu. Rev. Biochem. 1994, 63, 451-486.
    • (1994) Annu. Rev. Biochem , vol.63 , pp. 451-486
    • Tsai, M.J.1    O’Malley, B.W.2
  • 44
  • 45
    • 81255157751 scopus 로고    scopus 로고
    • Assessment of letrozole and tamoxifen alone and in sequence for postmenopausal women with steroid hormone receptor-positive breast cancer: The BIG 1-98 randomised clinical trial at 81 years median follow-up
    • Regan, M.M., Neven, P., Giobbie-Hurder, A., Goldhirsch, A., Ejlertsen, B., Mauriac, L., Forbes, J.F., Smith, I., Láng, I., Wardley, A., et al. Assessment of letrozole and tamoxifen alone and in sequence for postmenopausal women with steroid hormone receptor-positive breast cancer: The BIG 1-98 randomised clinical trial at 81 years median follow-up. Lancet Oncol. 2011, 12, 1101-1108.
    • (2011) Lancet Oncol , vol.12 , pp. 1101-1108
    • Regan, M.M.1    Neven, P.2    Giobbie-Hurder, A.3    Goldhirsch, A.4    Ejlertsen, B.5    Mauriac, L.6    Forbes, J.F.7    Smith, I.8    Láng, I.9    Wardley, A.10
  • 46
    • 23744473720 scopus 로고    scopus 로고
    • Aromatase inhibitors: Combinations with fulvestrant or signal transduction inhibitors as a strategy to overcome endocrine resistance
    • Johnston, S.R.D., Martin, L.-A., Head, J., Smith, I., Dowsett, M. Aromatase inhibitors: Combinations with fulvestrant or signal transduction inhibitors as a strategy to overcome endocrine resistance. J. Steroid Biochem. Mol. Biol. 2005, 95, 173-181.
    • (2005) J. Steroid Biochem. Mol. Biol , vol.95 , pp. 173-181
    • Johnston, S.R.D.1    Martin, L.-A.2    Head, J.3    Smith, I.4    Dowsett, M.5
  • 47
    • 85015787765 scopus 로고    scopus 로고
    • Fulvestrant plus targeted agents versus fulvestrant alone for treatment of hormone-receptor positive advanced breast cancer progressed on previous endocrine therapy: A meta-analysis of randomized controlled trials
    • Lin, W.-Z., Xu, Q.-N., Wang, H.-B., Li, X.-Y. Fulvestrant plus targeted agents versus fulvestrant alone for treatment of hormone-receptor positive advanced breast cancer progressed on previous endocrine therapy: A meta-analysis of randomized controlled trials. Breast Cancer 2017, 24, 345-352.
    • (2017) Breast Cancer , vol.24 , pp. 345-352
    • Lin, W.-Z.1    Xu, Q.-N.2    Wang, H.-B.3    Li, X.-Y.4
  • 48
    • 84942081183 scopus 로고    scopus 로고
    • The Long and Short of Tamoxifen Therapy: A Review of the ATLAS Trial
    • Smith, G.L. The Long and Short of Tamoxifen Therapy: A Review of the ATLAS Trial. J. Adv. Pract. Oncol. 2014, 5, 57-60.
    • (2014) J. Adv. Pract. Oncol , vol.5 , pp. 57-60
    • Smith, G.L.1
  • 50
    • 84878831559 scopus 로고    scopus 로고
    • Overcoming acquired resistance to anticancer therapy: Focus on the PI3K/AKT/mTOR pathway
    • Burris, H.A. Overcoming acquired resistance to anticancer therapy: Focus on the PI3K/AKT/mTOR pathway. Cancer Chemother. Pharmacol. 2013, 71, 829-842.
    • (2013) Cancer Chemother. Pharmacol , vol.71 , pp. 829-842
    • Burris, H.A.1
  • 51
    • 85015622723 scopus 로고    scopus 로고
    • Downregulation of microRNA-27b-3p enhances tamoxifen resistance in breast cancer by increasing NR5A2 and CREB1 expression
    • Zhu, J., Zou, Z., Nie, P., Kou, X., Wu, B., Wang, S., Song, Z., He, J. Downregulation of microRNA-27b-3p enhances tamoxifen resistance in breast cancer by increasing NR5A2 and CREB1 expression. Cell Death Dis. 2016, 7, e2454.
    • (2016) Cell Death Dis , vol.7
    • Zhu, J.1    Zou, Z.2    Nie, P.3    Kou, X.4    Wu, B.5    Wang, S.6    Song, Z.7    He, J.8
  • 52
    • 84961590445 scopus 로고    scopus 로고
    • Over-expression of miR-451a can enhance the sensitivity of breast cancer cells to tamoxifen by regulating 14-3-3ζ, estrogen receptor α, and autophagy
    • Liu, Z.-R., Song, Y., Wan, L.-H., Zhang, Y.-Y., Zhou, L.-M. Over-expression of miR-451a can enhance the sensitivity of breast cancer cells to tamoxifen by regulating 14-3-3ζ, estrogen receptor α, and autophagy. Life Sci. 2016, 149, 104-113.
    • (2016) Life Sci , vol.149 , pp. 104-113
    • Liu, Z.-R.1    Song, Y.2    Wan, L.-H.3    Zhang, Y.-Y.4    Zhou, L.-M.5
  • 54
    • 84920964253 scopus 로고    scopus 로고
    • Loss of estrogen-regulated microRNA expression increases HER2 signaling and is prognostic of poor outcome in luminal breast cancer
    • Bailey, S.T., Westerling, T., Brown, M. Loss of estrogen-regulated microRNA expression increases HER2 signaling and is prognostic of poor outcome in luminal breast cancer. Cancer Res. 2015, 75, 436-445.
    • (2015) Cancer Res , vol.75 , pp. 436-445
    • Bailey, S.T.1    Westerling, T.2    Brown, M.3
  • 55
    • 84949656235 scopus 로고    scopus 로고
    • MiR-214 increases the sensitivity of breast cancer cells to tamoxifen and fulvestrant through inhibition of autophagy
    • Yu, X., Luo, A., Liu, Y., Wang, S., Li, Y., Shi, W., Liu, Z., Qu, X. MiR-214 increases the sensitivity of breast cancer cells to tamoxifen and fulvestrant through inhibition of autophagy. Mol. Cancer 2015, 14, 208.
    • (2015) Mol. Cancer , vol.14 , pp. 208
    • Yu, X.1    Luo, A.2    Liu, Y.3    Wang, S.4    Li, Y.5    Shi, W.6    Liu, Z.7    Qu, X.8
  • 57
    • 84954539912 scopus 로고    scopus 로고
    • Silencing of microRNA-21 confers the sensitivity to tamoxifen and fulvestrant by enhancing autophagic cell death through inhibition of the PI3K-AKT-mTOR pathway in breast cancer cells
    • Yu, X., Li, R., Shi, W., Jiang, T., Wang, Y., Li, C., Qu, X. Silencing of microRNA-21 confers the sensitivity to tamoxifen and fulvestrant by enhancing autophagic cell death through inhibition of the PI3K-AKT-mTOR pathway in breast cancer cells. Biomed. Pharmacother. 2016, 77, 37-44.
    • (2016) Biomed. Pharmacother , vol.77 , pp. 37-44
    • Yu, X.1    Li, R.2    Shi, W.3    Jiang, T.4    Wang, Y.5    Li, C.6    Qu, X.7
  • 58
    • 84876883246 scopus 로고    scopus 로고
    • The discovery and development of selective estrogen receptor modulators (SERMs) for clinical practice
    • Maximov, P.Y., Lee, T.M., Jordan, V.C. The discovery and development of selective estrogen receptor modulators (SERMs) for clinical practice. Curr. Clin. Pharmacol. 2013, 8, 135-155.
    • (2013) Curr. Clin. Pharmacol , vol.8 , pp. 135-155
    • Maximov, P.Y.1    Lee, T.M.2    Jordan, V.C.3
  • 59
    • 85203363507 scopus 로고    scopus 로고
    • Relevance of breast cancer hormone receptors and other factors to the efficacy of adjuvant tamoxifen: Patient-level meta-analysis of randomised trials
    • Early Breast Cancer Trialists’ Collaborative Group (EBCTCG)
    • Early Breast Cancer Trialists’ Collaborative Group (EBCTCG), Davies, C., Godwin, J., Gray, R., Clarke, M., Cutter, D., Darby, S., McGale, P., Pan, H.C., Taylor, C., et al. Relevance of breast cancer hormone receptors and other factors to the efficacy of adjuvant tamoxifen: Patient-level meta-analysis of randomised trials. Lancet 2011, 378, 771-784.
    • (2011) Lancet , vol.378 , pp. 771-784
    • Davies, C.1    Godwin, J.2    Gray, R.3    Clarke, M.4    Cutter, D.5    Darby, S.6    McGale, P.7    Pan, H.C.8    Taylor, C.9
  • 61
    • 84886800908 scopus 로고    scopus 로고
    • Increased expression of miR-126 and miR-10a predict prolonged relapse-free time of primary oestrogen receptor-positive breast cancer following tamoxifen treatment
    • Hoppe, R., Achinger-Kawecka, J., Winter, S., Fritz, P., Lo, W.-Y., Schroth, W., Brauch, H. Increased expression of miR-126 and miR-10a predict prolonged relapse-free time of primary oestrogen receptor-positive breast cancer following tamoxifen treatment. Eur. J. Cancer 2013, 49, 3598-3608.
    • (2013) Eur. J. Cancer , vol.49 , pp. 3598-3608
    • Hoppe, R.1    Achinger-Kawecka, J.2    Winter, S.3    Fritz, P.4    Lo, W.-Y.5    Schroth, W.6    Brauch, H.7
  • 63
    • 85019172149 scopus 로고    scopus 로고
    • Functional role of miR-10b in tamoxifen resistance of ER-positive breast cancer cells through down-regulation of HDAC4
    • Ahmad, A., Ginnebaugh, K.R., Yin, S., Bollig-Fischer, A., Reddy, K.B., Sarkar, F.H. Functional role of miR-10b in tamoxifen resistance of ER-positive breast cancer cells through down-regulation of HDAC4. BMC Cancer 2015, 15, 540.
    • (2015) BMC Cancer , vol.15 , pp. 540
    • Ahmad, A.1    Ginnebaugh, K.R.2    Yin, S.3    Bollig-Fischer, A.4    Reddy, K.B.5    Sarkar, F.H.6
  • 64
  • 65
    • 84871229995 scopus 로고    scopus 로고
    • Trastuzumab: Updated mechanisms of action and resistance in breast cancer. Front
    • Vu, T., Claret, F.X. Trastuzumab: Updated mechanisms of action and resistance in breast cancer. Front. Oncol. 2012, 2, 62.
    • (2012) Oncol , vol.2 , pp. 62
    • Vu, T.1    Claret, F.X.2
  • 67
    • 85028268473 scopus 로고    scopus 로고
    • Akt phosphorylates and activates HSF-1 independent of heat shock, leading to Slug overexpression and epithelial-mesenchymal transition (EMT) of HER2-overexpressing breast cancer cells
    • Carpenter, R.L., Paw, I., Dewhirst, M.W., Lo, H.-W. Akt phosphorylates and activates HSF-1 independent of heat shock, leading to Slug overexpression and epithelial-mesenchymal transition (EMT) of HER2-overexpressing breast cancer cells. Oncogene 2015, 34, 546-557.
    • (2015) Oncogene , vol.34 , pp. 546-557
    • Carpenter, R.L.1    Paw, I.2    Dewhirst, M.W.3    Lo, H.-W.4
  • 68
    • 84947808033 scopus 로고    scopus 로고
    • MicroRNA-21 links epithelial-to-mesenchymal transition and inflammatory signals to confer resistance to neoadjuvant trastuzumab and chemotherapy in HER2-positive breast cancer patients
    • De Mattos-Arruda, L., Bottai, G., Nuciforo, P.G., Di Tommaso, L., Giovannetti, E., Peg, V., Losurdo, A., Pérez-Garcia, J., Masci, G., Corsi, F., et al. MicroRNA-21 links epithelial-to-mesenchymal transition and inflammatory signals to confer resistance to neoadjuvant trastuzumab and chemotherapy in HER2-positive breast cancer patients. Oncotarget 2015, 6, 37269-37280.
    • (2015) Oncotarget , vol.6 , pp. 37269-37280
    • De Mattos-Arruda, L.1    Bottai, G.2    Nuciforo, P.G.3    Di Tommaso, L.4    Giovannetti, E.5    Peg, V.6    Losurdo, A.7    Pérez-Garcia, J.8    Masci, G.9    Corsi, F.10
  • 69
    • 84988888007 scopus 로고    scopus 로고
    • A miRNA-based signature predicts development of disease recurrence in HER2 positive breast cancer after adjuvant trastuzumab-based treatment
    • Du, F., Yuan, P., Zhao, Z.T., Yang, Z., Wang, T., Zhao, J.D., Luo, Y., Ma, F., Wang, J.Y., Fan, Y., et al. A miRNA-based signature predicts development of disease recurrence in HER2 positive breast cancer after adjuvant trastuzumab-based treatment. Sci. Rep. 2016, 6, 33825.
    • (2016) Sci. Rep , vol.6 , pp. 33825
    • Du, F.1    Yuan, P.2    Zhao, Z.T.3    Yang, Z.4    Wang, T.5    Zhao, J.D.6    Luo, Y.7    Ma, F.8    Wang, J.Y.9    Fan, Y.10
  • 70
  • 71
    • 59149091637 scopus 로고    scopus 로고
    • MicroRNA regulation of DNA repair gene expression in hypoxic stress
    • Crosby, M.E., Kulshreshtha, R., Ivan, M., Glazer, P.M. MicroRNA regulation of DNA repair gene expression in hypoxic stress. Cancer Res. 2009, 69, 1221-1229.
    • (2009) Cancer Res , vol.69 , pp. 1221-1229
    • Crosby, M.E.1    Kulshreshtha, R.2    Ivan, M.3    Glazer, P.M.4
  • 72
    • 0035915421 scopus 로고    scopus 로고
    • Insulin-like growth factor-I receptor signaling and resistance to trastuzumab (Herceptin)
    • Lu, Y., Zi, X., Zhao, Y., Mascarenhas, D., Pollak, M. Insulin-like growth factor-I receptor signaling and resistance to trastuzumab (Herceptin). J. Natl. Cancer Inst. 2001, 93, 1852-1857.
    • (2001) J. Natl. Cancer Inst , vol.93 , pp. 1852-1857
    • Lu, Y.1    Zi, X.2    Zhao, Y.3    Mascarenhas, D.4    Pollak, M.5
  • 73
    • 84898601995 scopus 로고    scopus 로고
    • Epigenetic silencing of miR-375 induces trastuzumab resistance in HER2-positive breast cancer by targeting IGF1R
    • Ye, X.-M., Zhu, H.-Y., Bai, W.-D., Wang, T., Wang, L., Chen, Y., Yang, A.-G., Jia, L.-T. Epigenetic silencing of miR-375 induces trastuzumab resistance in HER2-positive breast cancer by targeting IGF1R. BMC Cancer 2014, 14, 134.
    • (2014) BMC Cancer , vol.14 , pp. 134
    • Ye, X.-M.1    Zhu, H.-Y.2    Bai, W.-D.3    Wang, T.4    Wang, L.5    Chen, Y.6    Yang, A.-G.7    Jia, L.-T.8
  • 75
    • 73149115341 scopus 로고    scopus 로고
    • Lapatinib combined with letrozole versus letrozole and placebo as first-line therapy for postmenopausal hormone receptor-positive metastatic breast cancer
    • Johnston, S., Pippen, J., Pivot, X., Lichinitser, M., Sadeghi, S., Dieras, V., Gomez, H.L., Romieu, G., Manikhas, A., Kennedy, M.J., et al. Lapatinib combined with letrozole versus letrozole and placebo as first-line therapy for postmenopausal hormone receptor-positive metastatic breast cancer. J. Clin. Oncol. 2009, 27, 5538-5546.
    • (2009) J. Clin. Oncol , vol.27 , pp. 5538-5546
    • Johnston, S.1    Pippen, J.2    Pivot, X.3    Lichinitser, M.4    Sadeghi, S.5    Dieras, V.6    Gomez, H.L.7    Romieu, G.8    Manikhas, A.9    Kennedy, M.J.10
  • 76
    • 0037068741 scopus 로고    scopus 로고
    • Anti-tumor activity of GW572016: A dual tyrosine kinase inhibitor blocks EGF activation of EGFR/erbB2 and downstream Erk1/2 and AKT pathways
    • Xia, W., Mullin, R.J., Keith, B.R., Liu, L.-H., Ma, H., Rusnak, D.W., Owens, G., Alligood, K.J., Spector, N.L. Anti-tumor activity of GW572016: A dual tyrosine kinase inhibitor blocks EGF activation of EGFR/erbB2 and downstream Erk1/2 and AKT pathways. Oncogene 2002, 21, 6255-6263.
    • (2002) Oncogene , vol.21 , pp. 6255-6263
    • Xia, W.1    Mullin, R.J.2    Keith, B.R.3    Liu, L.-H.4    Ma, H.5    Rusnak, D.W.6    Owens, G.7    Alligood, K.J.8    Spector, N.L.9
  • 78
    • 84908602324 scopus 로고    scopus 로고
    • Lapatinib with trastuzumab for HER2-positive early breast cancer (NeoALTTO): Survival outcomes of a randomised, open-label, multicentre, phase III trial and their association with pathological complete response
    • de Azambuja, E., Holmes, A.P., Piccart-Gebhart, M., Holmes, E., di Cosimo, S., Swaby, R.F., Untch, M., Jackisch, C., Lang, I., Smith, I., et al. Lapatinib with trastuzumab for HER2-positive early breast cancer (NeoALTTO): Survival outcomes of a randomised, open-label, multicentre, phase III trial and their association with pathological complete response. Lancet Oncol. 2014, 15, 1137-1146.
    • (2014) Lancet Oncol , vol.15 , pp. 1137-1146
    • De Azambuja, E.1    Holmes, A.P.2    Piccart-Gebhart, M.3    Holmes, E.4    Di Cosimo, S.5    Swaby, R.F.6    Untch, M.7    Jackisch, C.8    Lang, I.9    Smith, I.10
  • 79
    • 84880452171 scopus 로고    scopus 로고
    • Randomized trial of lapatinib versus placebo added to paclitaxel in the treatment of human epidermal growth factor receptor 2-overexpressing metastatic breast cancer
    • Guan, Z., Xu, B., DeSilvio, M.L., Shen, Z., Arpornwirat, W., Tong, Z., Lorvidhaya, V., Jiang, Z., Yang, J., Makhson, A., et al. Randomized trial of lapatinib versus placebo added to paclitaxel in the treatment of human epidermal growth factor receptor 2-overexpressing metastatic breast cancer. J. Clin. Oncol. 2013, 31, 1947-1953.
    • (2013) J. Clin. Oncol , vol.31 , pp. 1947-1953
    • Guan, Z.1    Xu, B.2    Desilvio, M.L.3    Shen, Z.4    Arpornwirat, W.5    Tong, Z.6    Lorvidhaya, V.7    Jiang, Z.8    Yang, J.9    Makhson, A.10
  • 80
    • 76449104021 scopus 로고    scopus 로고
    • Molecular predictors of response to trastuzumab and lapatinib in breast cancer
    • Esteva, F.J., Yu, D., Hung, M.-C., Hortobagyi, G.N. Molecular predictors of response to trastuzumab and lapatinib in breast cancer. Nat. Rev. Clin. Oncol. 2010, 7, 98-107.
    • (2010) Nat. Rev. Clin. Oncol. , vol.7 , pp. 98-107
    • Esteva, F.J.1    Yu, D.2    Hung, M.-C.3    Hortobagyi, G.N.4
  • 82
    • 84899132878 scopus 로고    scopus 로고
    • MiR-630 targets IGF1R to regulate response to HER-targeting drugs and overall cancer cell progression in HER2 over-expressing breast cancer
    • Corcoran, C., Rani, S., Breslin, S., Gogarty, M., Ghobrial, I.M., Crown, J., O’Driscoll, L. miR-630 targets IGF1R to regulate response to HER-targeting drugs and overall cancer cell progression in HER2 over-expressing breast cancer. Mol. Cancer 2014, 13, 71.
    • (2014) Mol. Cancer , vol.13 , pp. 71
    • Corcoran, C.1    Rani, S.2    Breslin, S.3    Gogarty, M.4    Ghobrial, I.M.5    Crown, J.6    O’Driscoll, L.7
  • 83
    • 33846587923 scopus 로고    scopus 로고
    • The basal subtype of breast carcinomas may represent the group of breast tumors that could benefit from EGFR-targeted therapies
    • Siziopikou, K.P., Cobleigh, M. The basal subtype of breast carcinomas may represent the group of breast tumors that could benefit from EGFR-targeted therapies. Breast Edinb. Scotl. 2007, 16, 104-107.
    • (2007) Breast Edinb. Scotl , vol.16 , pp. 104-107
    • Siziopikou, K.P.1    Cobleigh, M.2
  • 84
    • 69849105168 scopus 로고    scopus 로고
    • Estrogen receptor, progesterone receptor, human epidermal growth factor receptor 2 (HER2), and epidermal growth factor receptor expression and benefit from lapatinib in a randomized trial of paclitaxel with lapatinib or placebo as first-line treatment in HER2-negative or unknown metastatic breast cancer
    • Finn, R.S., Press, M.F., Dering, J., Arbushites, M., Koehler, M., Oliva, C., Williams, L.S., di Leo, A. Estrogen receptor, progesterone receptor, human epidermal growth factor receptor 2 (HER2), and epidermal growth factor receptor expression and benefit from lapatinib in a randomized trial of paclitaxel with lapatinib or placebo as first-line treatment in HER2-negative or unknown metastatic breast cancer. J. Clin. Oncol. 2009, 27, 3908-3915.
    • (2009) J. Clin. Oncol , vol.27 , pp. 3908-3915
    • Finn, R.S.1    Press, M.F.2    Dering, J.3    Arbushites, M.4    Koehler, M.5    Oliva, C.6    Williams, L.S.7    Di Leo, A.8
  • 86
    • 85017454926 scopus 로고    scopus 로고
    • The most prevalent side effects of pegylated liposomal doxorubicin monotherapy in women with metastatic breast cancer: A systematic review of clinical trials
    • Ansari, L., Shiehzadeh, F., Taherzadeh, Z., Nikoofal-Sahlabadi, S., Momtazi-Borojeni, A.A., Sahebkar, A., Eslami, S. The most prevalent side effects of pegylated liposomal doxorubicin monotherapy in women with metastatic breast cancer: A systematic review of clinical trials. Cancer Gene Ther. 2017, 24, 189-193.
    • (2017) Cancer Gene Ther , vol.24 , pp. 189-193
    • Ansari, L.1    Shiehzadeh, F.2    Taherzadeh, Z.3    Nikoofal-Sahlabadi, S.4    Momtazi-Borojeni, A.A.5    Sahebkar, A.6    Eslami, S.7
  • 87
    • 84992709496 scopus 로고    scopus 로고
    • A randomized phase III study evaluating pegylated liposomal doxorubicin versus capecitabine as first-line therapy for metastatic breast cancer: Results of the PELICAN study
    • Harbeck, N., Saupe, S., Jäger, E., Schmidt, M., Kreienberg, R., Müller, L., Otremba, B.J., Waldenmaier, D., Dorn, J., Warm, M., et al. A randomized phase III study evaluating pegylated liposomal doxorubicin versus capecitabine as first-line therapy for metastatic breast cancer: Results of the PELICAN study. Breast Cancer Res. Treat. 2017, 161, 63-72.
    • (2017) Breast Cancer Res. Treat , vol.161 , pp. 63-72
    • Harbeck, N.1    Saupe, S.2    Jäger, E.3    Schmidt, M.4    Kreienberg, R.5    Müller, L.6    Otremba, B.J.7    Waldenmaier, D.8    Dorn, J.9    Warm, M.10
  • 88
    • 84873890597 scopus 로고    scopus 로고
    • Chemotherapy regimens in early breast cancer: Major controversies and future outlook
    • Joerger, M., Thürlimann, B. Chemotherapy regimens in early breast cancer: Major controversies and future outlook. Expert Rev. Anticancer Ther. 2013, 13, 165-178.
    • (2013) Expert Rev. Anticancer Ther , vol.13 , pp. 165-178
    • Joerger, M.1    Thürlimann, B.2
  • 89
    • 84922210212 scopus 로고    scopus 로고
    • Systematic analysis of gene expression pattern in has-miR-760 overexpressed resistance of the MCF-7 human breast cancer cell to doxorubicin
    • Lv, J., Fu, Z., Shi, M., Xia, K., Ji, C., Xu, P., Lv, M., Pan, B., Dai, L., Xie, H. Systematic analysis of gene expression pattern in has-miR-760 overexpressed resistance of the MCF-7 human breast cancer cell to doxorubicin. Biomed. Pharmacother. 2015, 69, 162-169.
    • (2015) Biomed. Pharmacother , vol.69 , pp. 162-169
    • Lv, J.1    Fu, Z.2    Shi, M.3    Xia, K.4    Ji, C.5    Xu, P.6    Lv, M.7    Pan, B.8    Dai, L.9    Xie, H.10
  • 91
    • 84900397618 scopus 로고    scopus 로고
    • MicroRNA profiling implies new markers of chemoresistance of triple-negative breast cancer
    • Ouyang, M., Li, Y., Ye, S., Ma, J., Lu, L., Lv, W., Chang, G., Li, X., Li, Q., Wang, S., et al. MicroRNA profiling implies new markers of chemoresistance of triple-negative breast cancer. PLoS ONE 2014, 9, e96228.
    • (2014) Plos ONE , vol.9
    • Ouyang, M.1    Li, Y.2    Ye, S.3    Ma, J.4    Lu, L.5    Lv, W.6    Chang, G.7    Li, X.8    Li, Q.9    Wang, S.10
  • 92
    • 51049104524 scopus 로고    scopus 로고
    • Involvement of microRNA-451 in resistance of the MCF-7 breast cancer cells to chemotherapeutic drug doxorubicin. Mol
    • Kovalchuk, O., Filkowski, J., Meservy, J., Ilnytskyy, Y., Tryndyak, V.P., Chekhun, V.F., Pogribny, I.P. Involvement of microRNA-451 in resistance of the MCF-7 breast cancer cells to chemotherapeutic drug doxorubicin. Mol. Cancer Ther. 2008, 7, 2152-2159.
    • (2008) Cancer Ther , vol.7 , pp. 2152-2159
    • Kovalchuk, O.1    Filkowski, J.2    Meservy, J.3    Ilnytskyy, Y.4    Tryndyak, V.P.5    Chekhun, V.F.6    Pogribny, I.P.7
  • 93
    • 84938373367 scopus 로고    scopus 로고
    • A microRNA Expression Signature In Taxane-anthracycline-Based Neoadjuvant Chemotherapy Response
    • Zheng, Y., Li, S., Boohaker, R.J., Liu, X., Zhu, Y., Zhai, L., Li, H., Gu, F., Fan, Y., Lang, R., et al. A microRNA Expression Signature In Taxane-anthracycline-Based Neoadjuvant Chemotherapy Response. J. Cancer 2015, 6, 671-677.
    • (2015) J. Cancer , vol.6 , pp. 671-677
    • Zheng, Y.1    Li, S.2    Boohaker, R.J.3    Liu, X.4    Zhu, Y.5    Zhai, L.6    Li, H.7    Gu, F.8    Fan, Y.9    Lang, R.10
  • 94
    • 84960814022 scopus 로고    scopus 로고
    • Induction of miRNA-181a by genotoxic treatments promotes chemotherapeutic resistance and metastasis in breast cancer
    • Niu, J., Xue, A., Chi, Y., Xue, J., Wang, W., Zhao, Z., Fan, M., Yang, C.H., Shao, Z.-M., Pfeffer, L.M., et al. Induction of miRNA-181a by genotoxic treatments promotes chemotherapeutic resistance and metastasis in breast cancer. Oncogene 2016, 35, 1302-1313.
    • (2016) Oncogene , vol.35 , pp. 1302-1313
    • Niu, J.1    Xue, A.2    Chi, Y.3    Xue, J.4    Wang, W.5    Zhao, Z.6    Fan, M.7    Yang, C.H.8    Shao, Z.-M.9    Pfeffer, L.M.10
  • 95
    • 84896949069 scopus 로고    scopus 로고
    • MicroRNA expression profiling identifies a four microRNA signature as a novel diagnostic and prognostic biomarker in triple negative breast cancers
    • Gasparini, P., Cascione, L., Fassan, M., Lovat, F., Guler, G., Balci, S., Irkkan, C., Morrison, C., Croce, C.M., Shapiro, C.L., et al. MicroRNA expression profiling identifies a four microRNA signature as a novel diagnostic and prognostic biomarker in triple negative breast cancers. Oncotarget 2014, 5, 1174-1184.
    • (2014) Oncotarget , vol.5 , pp. 1174-1184
    • Gasparini, P.1    Cascione, L.2    Fassan, M.3    Lovat, F.4    Guler, G.5    Balci, S.6    Irkkan, C.7    Morrison, C.8    Croce, C.M.9    Shapiro, C.L.10
  • 96
    • 84923334405 scopus 로고    scopus 로고
    • Circulating miR-19a and miR-205 in serum may predict the sensitivity of luminal A subtype of breast cancer patients to neoadjuvant chemotherapy with epirubicin plus paclitaxel
    • Li, Q., Liu, M., Ma, F., Luo, Y., Cai, R., Wang, L., Xu, N., Xu, B. Circulating miR-19a and miR-205 in serum may predict the sensitivity of luminal A subtype of breast cancer patients to neoadjuvant chemotherapy with epirubicin plus paclitaxel. PLoS ONE 2014, 9, e104870.
    • (2014) Plos ONE , vol.9
    • Li, Q.1    Liu, M.2    Ma, F.3    Luo, Y.4    Cai, R.5    Wang, L.6    Xu, N.7    Xu, B.8
  • 97
    • 84994545584 scopus 로고    scopus 로고
    • MiR-222 promotes drug-resistance of breast cancer cells to adriamycin via modulation of PTEN/Akt/FOXO1 pathway
    • Shen, H., Wang, D., Li, L., Yang, S., Chen, X., Zhou, S., Zhong, S., Zhao, J., Tang, J. miR-222 promotes drug-resistance of breast cancer cells to adriamycin via modulation of PTEN/Akt/FOXO1 pathway. Gene 2017, 596, 110-118.
    • (2017) Gene , vol.596 , pp. 110-118
    • Shen, H.1    Wang, D.2    Li, L.3    Yang, S.4    Chen, X.5    Zhou, S.6    Zhong, S.7    Zhao, J.8    Tang, J.9
  • 99
    • 77956995581 scopus 로고    scopus 로고
    • Alterations of microRNAs and their targets are associated with acquired resistance of MCF-7 breast cancer cells to cisplatin
    • Pogribny, I.P., Filkowski, J.N., Tryndyak, V.P., Golubov, A., Shpyleva, S.I., Kovalchuk, O. Alterations of microRNAs and their targets are associated with acquired resistance of MCF-7 breast cancer cells to cisplatin. Int. J. Cancer 2010, 127, 1785-1794.
    • (2010) Int. J. Cancer , vol.127 , pp. 1785-1794
    • Pogribny, I.P.1    Filkowski, J.N.2    Tryndyak, V.P.3    Golubov, A.4    Shpyleva, S.I.5    Kovalchuk, O.6
  • 100
    • 84945245355 scopus 로고    scopus 로고
    • Knockdown of miR-221 promotes the cisplatin-inducing apoptosis by targeting the BIM-Bax/Bak axis in breast cancer
    • Ye, Z., Hao, R., Cai, Y., Wang, X., Huang, G. Knockdown of miR-221 promotes the cisplatin-inducing apoptosis by targeting the BIM-Bax/Bak axis in breast cancer. Tumour Biol. 2016, 37, 4509-4515.
    • (2016) Tumour Biol , vol.37 , pp. 4509-4515
    • Ye, Z.1    Hao, R.2    Cai, Y.3    Wang, X.4    Huang, G.5
  • 101
    • 84939856448 scopus 로고    scopus 로고
    • MiR-944 functions as a novel oncogene and regulates the chemoresistance in breast cancer
    • He, H., Tian, W., Chen, H., Jiang, K. miR-944 functions as a novel oncogene and regulates the chemoresistance in breast cancer. Tumour Biol. 2016, 37, 1599-1607.
    • (2016) Tumour Biol , vol.37 , pp. 1599-1607
    • He, H.1    Tian, W.2    Chen, H.3    Jiang, K.4
  • 102
    • 85016438976 scopus 로고    scopus 로고
    • MiR-519d impedes cisplatin-resistance in breast cancer stem cells by down-regulating the expression of MCL-1
    • Xie, Q., Wang, S., Zhao, Y., Zhang, Z., Qin, C., Yang, X. miR-519d impedes cisplatin-resistance in breast cancer stem cells by down-regulating the expression of MCL-1. Oncotarget 2017, 8, 22003-22013.
    • (2017) Oncotarget , vol.8 , pp. 22003-22013
    • Xie, Q.1    Wang, S.2    Zhao, Y.3    Zhang, Z.4    Qin, C.5    Yang, X.6
  • 103
    • 85010190235 scopus 로고    scopus 로고
    • MiR-199a-3p enhances breast cancer cell sensitivity to cisplatin by downregulating TFAM (TFAM). Biomed
    • Fan, X., Zhou, S., Zheng, M., Deng, X., Yi, Y., Huang, T. miR-199a-3p enhances breast cancer cell sensitivity to cisplatin by downregulating TFAM (TFAM). Biomed. Pharmacother. 2017, 88, 507-514.
    • (2017) Pharmacother , vol.88 , pp. 507-514
    • Fan, X.1    Zhou, S.2    Zheng, M.3    Deng, X.4    Yi, Y.5    Huang, T.6
  • 104
    • 85016414945 scopus 로고    scopus 로고
    • MiR-302b enhances breast cancer cell sensitivity to cisplatin by regulating E2F1 and the cellular DNA damage response
    • Cataldo, A., Cheung, D.G., Balsari, A., Tagliabue, E., Coppola, V., Iorio, M.V., Palmieri, D., Croce, C.M. miR-302b enhances breast cancer cell sensitivity to cisplatin by regulating E2F1 and the cellular DNA damage response. Oncotarget 2016, 7, 786-797.
    • (2016) Oncotarget , vol.7 , pp. 786-797
    • Cataldo, A.1    Cheung, D.G.2    Balsari, A.3    Tagliabue, E.4    Coppola, V.5    Iorio, M.V.6    Palmieri, D.7    Croce, C.M.8
  • 105
    • 84930883853 scopus 로고    scopus 로고
    • MiR-218 regulates cisplatin chemosensitivity in breast cancer by targeting BRCA1
    • He, X., Xiao, X., Dong, L., Wan, N., Zhou, Z., Deng, H., Zhang, X. miR-218 regulates cisplatin chemosensitivity in breast cancer by targeting BRCA1. Tumour Biol. 2015, 36, 2065-2075.
    • (2015) Tumour Biol , vol.36 , pp. 2065-2075
    • He, X.1    Xiao, X.2    Dong, L.3    Wan, N.4    Zhou, Z.5    Deng, H.6    Zhang, X.7
  • 106
    • 84988888028 scopus 로고    scopus 로고
    • MiR-638 mediated regulation of BRCA1 affects DNA repair and sensitivity to UV and cisplatin in triple-negative breast cancer
    • Tan, X., Peng, J., Fu, Y., An, S., Rezaei, K., Tabbara, S., Teal, C.B., Man, Y., Brem, R.F., Fu, S.W. miR-638 mediated regulation of BRCA1 affects DNA repair and sensitivity to UV and cisplatin in triple-negative breast cancer. Breast Cancer Res. 2014, 16, 435.
    • (2014) Breast Cancer Res , vol.16 , pp. 435
    • Tan, X.1    Peng, J.2    Fu, Y.3    An, S.4    Rezaei, K.5    Tabbara, S.6    Teal, C.B.7    Man, Y.8    Brem, R.F.9    Fu, S.W.10
  • 108
    • 84890333189 scopus 로고    scopus 로고
    • 5-FU and ixabepilone modify the microRNA expression profiles in MDA-MB-453 triple-negative breast cancer cells. Oncol
    • Yao, Y., Chen, S., Zhou, X., Xie, L., Chen, A. 5-FU and ixabepilone modify the microRNA expression profiles in MDA-MB-453 triple-negative breast cancer cells. Oncol. Lett. 2014, 7, 541-547.
    • (2014) Lett , vol.7 , pp. 541-547
    • Yao, Y.1    Chen, S.2    Zhou, X.3    Xie, L.4    Chen, A.5
  • 110
    • 84919681039 scopus 로고    scopus 로고
    • MicroRNA expression profiling and bioinformatics analysis of dysregulated microRNAs in vinorelbine-resistant breast cancer cells
    • Zhong, S., Ma, T., Zhang, X., Lv, M., Chen, L., Tang, J., Zhao, J. MicroRNA expression profiling and bioinformatics analysis of dysregulated microRNAs in vinorelbine-resistant breast cancer cells. Gene 2015, 556, 113-118.
    • (2015) Gene , vol.556 , pp. 113-118
    • Zhong, S.1    Ma, T.2    Zhang, X.3    Lv, M.4    Chen, L.5    Tang, J.6    Zhao, J.7
  • 112
    • 84892987414 scopus 로고    scopus 로고
    • Effects of the addition of gemcitabine, and paclitaxel-first sequencing, in neoadjuvant sequential epirubicin, cyclophosphamide, and paclitaxel for women with high-risk early breast cancer (Neo-tAnGo): An open-label, 2 × 2 factorial randomised phase III trial
    • Earl, H.M., Vallier, A.-L., Hiller, L., Fenwick, N., Young, J., Iddawela, M., Abraham, J., Hughes-Davies, L., Gounaris, I., McAdam, K., et al. Effects of the addition of gemcitabine, and paclitaxel-first sequencing, in neoadjuvant sequential epirubicin, cyclophosphamide, and paclitaxel for women with high-risk early breast cancer (Neo-tAnGo): An open-label, 2 × 2 factorial randomised phase III trial. Lancet Oncol. 2014, 15, 201-212.
    • (2014) Lancet Oncol , vol.15 , pp. 201-212
    • Earl, H.M.1    Vallier, A.-L.2    Hiller, L.3    Fenwick, N.4    Young, J.5    Iddawela, M.6    Abraham, J.7    Hughes-Davies, L.8    Gounaris, I.9    McAdam, K.10
  • 113
    • 84949770766 scopus 로고    scopus 로고
    • MiRNA-21 induces epithelial to mesenchymal transition and gemcitabine resistance via the PTEN/AKT pathway in breast cancer
    • Wu, Z.-H., Tao, Z.-H., Zhang, J., Li, T., Ni, C., Xie, J., Zhang, J.-F., Hu, X.-C. miRNA-21 induces epithelial to mesenchymal transition and gemcitabine resistance via the PTEN/AKT pathway in breast cancer. Tumour Biol. 2016, 37, 7245-7254.
    • (2016) Tumour Biol , vol.37 , pp. 7245-7254
    • Wu, Z.-H.1    Tao, Z.-H.2    Zhang, J.3    Li, T.4    Ni, C.5    Xie, J.6    Zhang, J.-F.7    Hu, X.-C.8


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