The E3 Ligase CHIP mediates p21 degradation to maintain radioresistance

Molecular Cancer Research

Volumn 15, Issue 6, 2017, Pages 651-659

  Biswas, Kuntal ^a   Sarkar, Sukumar ^a   Du, Kangping ^a   Brautigan, David L ^b   Abbas, Tarek ^a,b   Larner, James M ^a  

^a UNIVERSITY OF VIRGINIA   (United States)

^b UNIVERSITY OF VIRGINIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

48 LINKED UBIQUITIN; ATM PROTEIN; BENZYLOXYCARBONYLLEUCYLLEUCYLLEUCINAL; C TERMINUS OF HSC70 INTERACTING PROTEIN; CYCLIN D1; CYCLIN DEPENDENT KINASE 6; CYCLIN DEPENDENT KINASE INHIBITOR 1; DNA DEPENDENT PROTEIN KINASE; HEAT SHOCK PROTEIN 40; HEAT SHOCK PROTEIN 70; HISTONE H2AX; KAP1 PROTEIN; PEPTIDES AND PROTEINS; PROTEIN MDM2; PROTEIN P53; SHORT HAIRPIN RNA; SMALL INTERFERING RNA; TUBULIN; UBIQUITIN; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG; CDKN1A PROTEIN, HUMAN; CYCLIN DEPENDENT KINASE INHIBITOR 1A; STUB1 PROTEIN, HUMAN; UBIQUITIN PROTEIN LIGASE;

A-549 CELL LINE; ARTICLE; CANCER RADIOTHERAPY; CELLULAR SENESCENCE; CELLULAR STRESS RESPONSE; CELLULAR, SUBCELLULAR AND MOLECULAR BIOLOGICAL PHENOMENA AND FUNCTIONS; CONTROLLED STUDY; CRISPR CAS SYSTEM; GENE DELETION; GENE OVEREXPRESSION; GENE SILENCING; HUMAN; HUMAN CELL; IN VITRO STUDY; IONIZING RADIATION; LUNG CANCER CELL LINE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PROTEIN INTERACTION; RADIATION EXPOSURE; RADIATION RESPONSE; RADIOSENSITIVITY; RESAZURIN ASSAY; SENESCENCE; UBIQUITINATION; GENE KNOCKDOWN; GENETICS; LUNG TUMOR; METABOLISM; PATHOLOGY; RADIATION TOLERANCE; TUMOR CELL LINE;

CELL LINE, TUMOR; CRISPR-CAS SYSTEMS; CYCLIN-DEPENDENT KINASE INHIBITOR P21; GENE KNOCKDOWN TECHNIQUES; HSP40 HEAT-SHOCK PROTEINS; HSP70 HEAT-SHOCK PROTEINS; HUMANS; LUNG NEOPLASMS; PROTEOLYSIS; RADIATION TOLERANCE; RADIATION, IONIZING; UBIQUITIN-PROTEIN LIGASES; UBIQUITINATION;

EID: 85020388158     PISSN: 15417786     EISSN: 15573125     Source Type: Journal    
DOI: 10.1158/1541-7786.MCR-16-0466     Document Type: Article

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