메뉴 건너뛰기




Volumn 12, Issue 6, 2017, Pages

Single dose primaquine to reduce gametocyte carriage and Plasmodium falciparum transmission in Cambodia: An open-label randomized trial

Author keywords

[No Author keywords available]

Indexed keywords

ARTEMISININ; DIHYDROARTEMISININ PLUS PIPERAQUINE; PRIMAQUINE; ANTIMALARIAL AGENT; ARTEMISININ DERIVATIVE; DRUG COMBINATION;

EID: 85020276557     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0168702     Document Type: Article
Times cited : (29)

References (44)
  • 1
    • 57549094606 scopus 로고    scopus 로고
    • Global malaria control and elimination
    • World Health Organization April
    • World Health Organization. Global malaria control and elimination. Report of a meeting on containment of artemisinin tolerance, April 2008. http://www.who.int/malaria/publications/atoz/9789241596817/en/.
    • (2008) Report of A Meeting on Containment of Artemisinin Tolerance
  • 2
    • 84939258746 scopus 로고    scopus 로고
    • Spatial and temporal epidemiology of clinical malaria in Cambodia 2004-2013
    • Maude RJ, Nguon C, Ly P, Bunkea T, Ngor P, Canavati de la Torre SE, et al. Spatial and temporal epidemiology of clinical malaria in Cambodia 2004-2013. Malar J. 2014; 13: 385. doi: 10.1186/1475-2875-13-385
    • (2014) Malar J , vol.13 , pp. 385
    • Maude, R.J.1    Nguon, C.2    Ly, P.3    Bunkea, T.4    Ngor, P.5    De La Torre, C.S.E.6
  • 3
    • 84904892931 scopus 로고    scopus 로고
    • Spread of artemisinin resistance in Plasmodium falciparum malaria
    • Ashley EA, Dhorda M, Fairhurst RM, Amaratunga C, Lim P, Suon S, et al. Spread of artemisinin resistance in Plasmodium falciparum malaria. N Engl J Med. 2014; 371: 411-423. doi: 10.1056/NEJMoa1314981
    • (2014) N Engl J Med , vol.371 , pp. 411-423
    • Ashley, E.A.1    Dhorda, M.2    Fairhurst, R.M.3    Amaratunga, C.4    Lim, P.5    Suon, S.6
  • 4
    • 84904861610 scopus 로고    scopus 로고
    • Military malaria research program, national center for parasitology, entomology, and malaria control (cnm), royal cambodian armed forces
    • Saunders DL, Vanachayangkul P, Lon C, U.S. Army Military Malaria Research Program, National Center for Parasitology, Entomology, and Malaria Control (CNM), Royal Cambodian Armed Forces. Dihydroartemisinin-piperaquine failure in Cambodia. N Engl J Med. 2014; 371: 484-485. doi: 10.1056/NEJMc1403007
    • (2014) Dihydroartemisinin-piperaquine Failure in Cambodia. N Engl J Med , vol.371 , pp. 484-485
    • Saunders, D.L.1    Vanachayangkul, P.2    Lon, C.3    Army, U.S.4
  • 5
    • 84929513620 scopus 로고    scopus 로고
    • Dihydroartemisinin-piperaquine failure associated with a triple mutant including kelch13 C580Y in Cambodia: An observational cohort study
    • Spring MD, Lin JT, Manning JE, Vanachayangkul P, Somethy S, Bun R, et al. Dihydroartemisinin-piperaquine failure associated with a triple mutant including kelch13 C580Y in Cambodia: An observational cohort study. Lancet Infect Dis. 2015; 15: 683-691. doi: 10.1016/S1473-3099(15)70049-6
    • (2015) Lancet Infect Dis , vol.15 , pp. 683-691
    • Spring, M.D.1    Lin, J.T.2    Manning, J.E.3    Vanachayangkul, P.4    Somethy, S.5    Bun, R.6
  • 6
    • 84939832774 scopus 로고    scopus 로고
    • Evidence of plasmodium falciparum malaria multidrug resistance to artemisinin and piperaquine in western Cambodia: Dihydroartemisinin-piperaquine open-label multicenter clinical assessment
    • Leang R, Taylor WRJ, Bouth DM, Song L, Tarning J, Char MC, et al. Evidence of Plasmodium falciparum Malaria Multidrug Resistance to Artemisinin and Piperaquine in Western Cambodia: Dihydroartemisinin-Piperaquine Open-Label Multicenter Clinical Assessment. Antimicrob Agents Chemother. 2015; 59: 4719-4726. doi: 10.1128/AAC.00835-15
    • (2015) Antimicrob Agents Chemother , vol.59 , pp. 4719-4726
    • Leang, R.1    Wrj, T.2    Bouth, D.M.3    Song, L.4    Tarning, J.5    Char, M.C.6
  • 7
    • 85020282825 scopus 로고    scopus 로고
    • Guidelines for the treatment of malaria
    • World Health Organization
    • World Health Organization. Guidelines for the Treatment of Malaria, 2010. Geneva: World Health Organization; 2010.
    • (2010) Geneva World Health Organization , vol.2010
  • 8
    • 77957134420 scopus 로고    scopus 로고
    • Effectiveness of five artemisinin combination regimens with or without primaquine in uncomplicated falciparum malaria: An open-label randomised trial
    • Smithuis F, Kyaw MK, Phe O, Win T, Aung PP, Oo APP, et al. Effectiveness of five artemisinin combination regimens with or without primaquine in uncomplicated falciparum malaria: An open-label randomised trial. Lancet Infect Dis. 2010; 10: 673-681. doi: 10.1016/S1473-3099(10)70187-0
    • (2010) Lancet Infect Dis , vol.10 , pp. 673-681
    • Smithuis, F.1    Kyaw, M.K.2    Phe, O.3    Win, T.4    Aung, P.P.5    App, O.6
  • 9
    • 41749083511 scopus 로고    scopus 로고
    • Primaquine clears submicroscopic Plasmodium falciparum gametocytes that persist after treatment with sulphadoxinepyrimethamine and artesunate
    • Shekalaghe S, Drakeley C, Gosling R, Ndaro A, van Meegeren M, Enevold A, et al. Primaquine clears submicroscopic Plasmodium falciparum gametocytes that persist after treatment with sulphadoxinepyrimethamine and artesunate. PloS One. 2007; 2: e1023. doi: 10.1371/journal.pone.0001023
    • (2007) PloS One , vol.2 , pp. e1023
    • Shekalaghe, S.1    Drakeley, C.2    Gosling, R.3    Ndaro, A.4    Van Meegeren, M.5    Enevold, A.6
  • 11
    • 77952496627 scopus 로고    scopus 로고
    • Revisiting the circulation time of Plasmodium falciparum gametocytes: Molecular detection methods to estimate the duration of gametocyte carriage and the effect of gametocytocidal drugs
    • Bousema T, Okell L, Shekalaghe S, Griffin JT, Omar S, Sawa P, et al. Revisiting the circulation time of Plasmodium falciparum gametocytes: molecular detection methods to estimate the duration of gametocyte carriage and the effect of gametocytocidal drugs. Malar J. 2010; 9: 136. doi: 10.1186/1475-2875-9-136
    • (2010) Malar J , vol.9 , Issue.136 , pp. 136
    • Bousema, T.1    Okell, L.2    Shekalaghe, S.3    Griffin, J.T.4    Omar, S.5    Sawa, P.6
  • 12
    • 84872595849 scopus 로고    scopus 로고
    • Primaquine to prevent transmission of falciparum malaria
    • White NJ. Primaquine to prevent transmission of falciparum malaria. Lancet Infect Dis. 2013; 13: 175-181. doi: 10.1016/S1473-3099(12)70198-6
    • (2013) Lancet Infect Dis , vol.13 , pp. 175-181
    • White, N.J.1
  • 13
    • 0027993177 scopus 로고
    • The infectivity of gametocytes of Plasmodium falciparum from patients treated with artemisinin
    • Chen PQ, Li GQ, Guo XB, He KR, Fu YX, Fu LC, et al. The infectivity of gametocytes of Plasmodium falciparum from patients treated with artemisinin. Chin Med J (Engl). 1994; 107: 709-711.
    • (1994) Chin Med J (Engl) , vol.107 , pp. 709-711
    • Chen, P.Q.1    Li, G.Q.2    Guo, X.B.3    He, K.R.4    Fu, Y.X.5    Fu, L.C.6
  • 14
    • 84958581636 scopus 로고    scopus 로고
    • Primaquine to reduce transmission of Plasmodium falciparum malaria in Mali: A single-blind, dose-ranging, adaptive randomised phase 2 trial
    • Dicko A, Brown JM, Diawara H, Baber I, Mahamar A, Soumare HM, et al. Primaquine to reduce transmission of Plasmodium falciparum malaria in Mali: A single-blind, dose-ranging, adaptive randomised phase 2 trial. Lancet Infect Dis. 2016;
    • (2016) Lancet Infect Dis
    • Dicko, A.1    Brown, J.M.2    Diawara, H.3    Baber, I.4    Mahamar, A.5    Soumare, H.M.6
  • 15
    • 79955942990 scopus 로고    scopus 로고
    • Artesunate dose escalation for the treatment of uncomplicated malaria in a region of reported artemisinin resistance: A randomized clinical trial
    • Bethell D, Se Y, Lon C, Tyner S, Saunders D, Sriwichai S, et al. Artesunate dose escalation for the treatment of uncomplicated malaria in a region of reported artemisinin resistance: A randomized clinical trial. PloS One. 2011; 6: e19283. doi: 10.1371/journal.pone.0019283
    • (2011) PloS One , vol.6 , pp. e19283
    • Bethell, D.1    Se, Y.2    Lon, C.3    Tyner, S.4    Saunders, D.5    Sriwichai, S.6
  • 16
    • 39549117157 scopus 로고    scopus 로고
    • A filter paper method for the detection of Plasmodium falciparum gametocytes by reverse transcription polymerase chain reaction
    • Mlambo G, Vasquez Y, LeBlanc R, Sullivan D, Kumar N. A filter paper method for the detection of Plasmodium falciparum gametocytes by reverse transcription polymerase chain reaction. Am J Trop Med Hyg. 2008; 78: 114-116.
    • (2008) Am J Trop Med Hyg , vol.78 , pp. 114-116
    • Mlambo, G.1    Vasquez, Y.2    LeBlanc, R.3    Sullivan, D.4    Kumar, N.5
  • 17
    • 79955390430 scopus 로고    scopus 로고
    • Plasmodium falciparum gametocyte carriage is associated with subsequent Plasmodium vivax relapse after treatment
    • Lin JT, Bethell D, Tyner SD, Lon C, Shah NK, Saunders DL, et al. Plasmodium falciparum gametocyte carriage is associated with subsequent Plasmodium vivax relapse after treatment. PloS One. 2011; 6: e18716. doi: 10.1371/journal.pone.0018716
    • (2011) PloS One , vol.6 , pp. e18716
    • Lin, J.T.1    Bethell, D.2    Tyner, S.D.3    Lon, C.4    Shah, N.K.5    Saunders, D.L.6
  • 18
    • 84971601539 scopus 로고    scopus 로고
    • Microscopic plasmodium falciparum gametocytemia and infectivity to mosquitoes in Cambodia
    • Lin JT, Ubalee R, Lon C, Balasubramanian S, Kuntawunginn W, Rahman R, et al. Microscopic Plasmodium falciparum Gametocytemia and Infectivity to Mosquitoes in Cambodia. J Infect Dis. 2016; 213: 1491-1494. doi: 10.1093/infdis/jiv599
    • (2016) J Infect Dis , vol.213 , pp. 1491-1494
    • Lin, J.T.1    Ubalee, R.2    Lon, C.3    Balasubramanian, S.4    Kuntawunginn, W.5    Rahman, R.6
  • 19
    • 85007413383 scopus 로고    scopus 로고
    • Single low dose primaquine to reduce gametocyte carriage and Plasmodium falciparum transmission after artemetherlumefantrine in children with asymptomatic infection: A randomised, double-blind, placebo-controlled trial
    • Goncalves BP, Tiono AB, OueÂdraogo A, GuelbeÂogo WM, Bradley J, Nebie I, et al. Single low dose primaquine to reduce gametocyte carriage and Plasmodium falciparum transmission after artemetherlumefantrine in children with asymptomatic infection: A randomised, double-blind, placebo-controlled trial. BMC Med. 2016; 14: 40. doi: 10.1186/s12916-016-0581-y
    • (2016) BMC Med , vol.14 , pp. 40
    • Goncalves, B.P.1    Tiono, A.B.2    Oueâdraogo, A.3    Guelbeâogo, W.M.4    Bradley, J.5    Nebie, I.6
  • 20
    • 84891684080 scopus 로고    scopus 로고
    • Malaria vectors in the greater mekong subregion: Overview of malaria vectors and remaining challenges
    • discussion 306-307
    • Hii J, Rueda LM. Malaria vectors in the Greater Mekong Subregion: overview of malaria vectors and remaining challenges. Southeast Asian J Trop Med Public Health. 2013; 44 Suppl 1: 73-165; discussion 306-307.
    • (2013) Southeast Asian J Trop Med Public Health , vol.44 , Issue.1 , pp. 73-165
    • Hii, J.1    Rueda, L.M.2
  • 21
    • 84875930363 scopus 로고    scopus 로고
    • World Health Organization October Accessed 20 May 2016 Updated WHO Policy REcommendation
    • World Health Organization. Updated WHO Policy REcommendation (October 2012): Single dose Primaquine as a gametocytocide in Plasmodium falciparum malaria. http://www.who.int/malaria/pq-updated-policy-recommendation-en-102012.pdf. Accessed 20 May 2016.
    • (2012) Single Dose Primaquine As A Gametocytocide in Plasmodium Falciparum Malaria
  • 22
    • 84870891528 scopus 로고    scopus 로고
    • Rationale for recommending a lower dose of primaquine as a Plasmodium falciparum gametocytocide in populations where G6PD deficiency is common
    • White NJ, Qiao LG, Qi G, Luzzatto L. Rationale for recommending a lower dose of primaquine as a Plasmodium falciparum gametocytocide in populations where G6PD deficiency is common. Malar J. 2012; 11: 418. doi: 10.1186/1475-2875-11-418
    • (2012) Malar J , vol.11 , pp. 418
    • White, N.J.1    Qiao, L.G.2    Qi, G.3    Luzzatto, L.4
  • 23
    • 0026674717 scopus 로고
    • Acute intravascular haemolysis in Vanuatu following a single dose of primaquine in individuals with glucose-6-phosphate dehydrogenase deficiency
    • Reeve PA, Toaliu H, Kaneko A, Hall JJ, Ganczakowski M. Acute intravascular haemolysis in Vanuatu following a single dose of primaquine in individuals with glucose-6-phosphate dehydrogenase deficiency. J Trop Med Hyg. 1992; 95: 349-351.
    • (1992) J Trop Med Hyg , vol.95 , pp. 349-351
    • Reeve, P.A.1    Toaliu, H.2    Kaneko, A.3    Hall, J.J.4    Ganczakowski, M.5
  • 24
    • 84920774125 scopus 로고    scopus 로고
    • Primaquine: The risks and the benefits
    • Ashley EA, Recht J, White NJ. Primaquine: The risks and the benefits. Malar J. 2014; 13: 418. doi: 10. 1186/1475-2875-13-418
    • (2014) Malar J , vol.13 , pp. 418
    • Ashley, E.A.1    Recht, J.2    White, N.J.3
  • 25
    • 77951218489 scopus 로고    scopus 로고
    • Tanzania, hemolysis after a single dose of primaquine coadministered with an artemisinin is not restricted to glucose-6-phosphate dehydrogenase-deficient (g6pd a-) individuals
    • Shekalaghe SA, ter Braak R, Daou M, Kavishe R, van den Bijllaardt W, van den Bosch S, et al. In Tanzania, hemolysis after a single dose of primaquine coadministered with an artemisinin is not restricted to glucose-6-phosphate dehydrogenase-deficient (G6PD A-) individuals. Antimicrob Agents Chemother. 2010; 54: 1762-1768. doi: 10.1128/AAC.01135-09
    • (2010) Antimicrob Agents Chemother , vol.54 , pp. 1762-1768
    • Shekalaghe, S.A.1    Braak, R.2    Daou, M.3    Kavishe, R.4    Van Den Bijllaardt, W.5    Van Den Bosch, S.6
  • 26
    • 84962050336 scopus 로고    scopus 로고
    • Single low dose primaquine (0.25mg/kg) does not cause clinically significant haemolysis in g6pd deficient subjects
    • Bancone G, Chowwiwat N, Somsakchaicharoen R, Poodpanya L, Moo PK, Gornsawun G, et al. Single Low Dose Primaquine (0.25mg/kg) Does Not Cause Clinically Significant Haemolysis in G6PD Deficient Subjects. PloS One. 2016; 11: e0151898. doi: 10.1371/journal.pone.0151898
    • (2016) PloS One , vol.11 , pp. e0151898
    • Bancone, G.1    Chowwiwat, N.2    Somsakchaicharoen, R.3    Poodpanya, L.4    Moo, P.K.5    Gornsawun, G.6
  • 27
    • 84892519249 scopus 로고    scopus 로고
    • Single dose primaquine for clearance of Plasmodium falciparum gametocytes in children with uncomplicated malaria in Uganda: A randomised, controlled, double-blind, dose-ranging trial
    • Eziefula AC, Bousema T, Yeung S, Kamya M, Owaraganise A, Gabagaya G, et al. Single dose primaquine for clearance of Plasmodium falciparum gametocytes in children with uncomplicated malaria in Uganda: A randomised, controlled, double-blind, dose-ranging trial. Lancet Infect Dis. 2014; 14: 130-139. doi: 10.1016/S1473-3099(13)70268-8
    • (2014) Lancet Infect Dis , vol.14 , pp. 130-139
    • Eziefula, A.C.1    Bousema, T.2    Yeung, S.3    Kamya, M.4    Owaraganise, A.5    Gabagaya, G.6
  • 28
    • 84890161948 scopus 로고    scopus 로고
    • The relevance and applicability of oocyst prevalence as a read-out for mosquito feeding assays
    • Stone WJR, Eldering M, van Gemert G-J, Lanke KHW, Grignard L, van de Vegte-Bolmer MG, et al. The relevance and applicability of oocyst prevalence as a read-out for mosquito feeding assays. Sci Rep. 2013; 3: 3418. doi: 10.1038/srep03418
    • (2013) Sci Rep , vol.3 , pp. 3418
    • Wjr, S.1    Eldering, M.2    Van Gemert, G.-J.3    Khw, L.4    Grignard, L.5    Van De Vegte-Bolmer, M.G.6
  • 30
    • 84969921822 scopus 로고    scopus 로고
    • Gametocyte carriage in uncomplicated Plasmodium falciparum malaria following treatment with artemisinin combination therapy: A systematic review and meta-Analysis of individual patient data
    • WWARN Gametocyte Study Group
    • WWARN Gametocyte Study Group. Gametocyte carriage in uncomplicated Plasmodium falciparum malaria following treatment with artemisinin combination therapy: A systematic review and meta-Analysis of individual patient data. BMC Med. 2016; 14: 79. doi: 10.1186/s12916-016-0621-7
    • (2016) BMC Med , vol.14 , pp. 79
  • 31
    • 84858449712 scopus 로고    scopus 로고
    • Changes in the treatment responses to artesunate-mefloquine on the northwestern border of Thailand during 13 years of continuous deployment
    • Carrara VI, Zwang J, Ashley EA, Price RN, Stepniewska K, Barends M, et al. Changes in the treatment responses to artesunate-mefloquine on the northwestern border of Thailand during 13 years of continuous deployment. PloS One. 2009; 4: e4551. doi: 10.1371/journal.pone.0004551
    • (2009) PloS One , vol.4 , pp. e4551
    • Carrara, V.I.1    Zwang, J.2    Ashley, E.A.3    Price, R.N.4    Stepniewska, K.5    Barends, M.6
  • 32
    • 84861461519 scopus 로고    scopus 로고
    • Emergence of artemisininresistant malaria on the western border of Thailand: A longitudinal study
    • Phyo AP, Nkhoma S, Stepniewska K, Ashley EA, Nair S, McGready R, et al. Emergence of artemisininresistant malaria on the western border of Thailand: A longitudinal study. Lancet Lond Engl. 2012; 379: 1960-1966.
    • (2012) Lancet Lond Engl , vol.379 , pp. 1960-1966
    • Phyo, A.P.1    Nkhoma, S.2    Stepniewska, K.3    Ashley, E.A.4    Nair, S.5    McGready, R.6
  • 33
    • 84873633438 scopus 로고    scopus 로고
    • The effect of primaquine on gametocyte development and clearance in the treatment of uncomplicated falciparum malaria with dihydroartemisinin-piperaquine in South sumatra, Western Indonesia: An open-label, randomized, controlled trial
    • Sutanto I, Suprijanto S, Kosasih A, Dahlan MS, Syafruddin D, Kusriastuti R, et al. The effect of primaquine on gametocyte development and clearance in the treatment of uncomplicated falciparum malaria with dihydroartemisinin-piperaquine in South sumatra, Western indonesia: An open-label, randomized, controlled trial. Clin Infect Dis Off Publ Infect Dis Soc Am. 2013; 56: 685-693.
    • (2013) Clin Infect Dis off Publ Infect Dis Soc Am , vol.56 , pp. 685-693
    • Sutanto, I.1    Suprijanto, S.2    Kosasih, A.3    Dahlan, M.S.4    Syafruddin, D.5    Kusriastuti, R.6
  • 34
    • 84971631275 scopus 로고    scopus 로고
    • Infectivity of microscopic and submicroscopic malaria parasite infections in areas of low malaria endemicity
    • Goncalves BP, Drakeley C, Bousema T. Infectivity of Microscopic and Submicroscopic Malaria Parasite Infections in Areas of Low Malaria Endemicity. J Infect Dis. 2016; 213: 1516-1517. doi: 10.1093/infdis/jiw044
    • (2016) J Infect Dis , vol.213 , pp. 1516-1517
    • Goncalves, B.P.1    Drakeley, C.2    Bousema, T.3
  • 36
    • 84897080014 scopus 로고    scopus 로고
    • The role of submicroscopic parasitemia in malaria transmission: What is the evidence
    • Lin JT, Saunders DL, Meshnick SR. The role of submicroscopic parasitemia in malaria transmission: what is the evidence? Trends Parasitol. 2014; 30: 183-190. doi: 10.1016/j.pt.2014.02.004
    • (2014) Trends Parasitol , vol.30 , pp. 183-190
    • Lin, J.T.1    Saunders, D.L.2    Meshnick, S.R.3
  • 37
    • 68149158508 scopus 로고    scopus 로고
    • Safety and efficacy of dihydroartemisinin-piperaquine in falciparum malaria: A prospective multi-centre individual patient data analysis
    • Zwang J, Ashley EA, Karema C, D'Alessandro U, Smithuis F, Dorsey G, et al. Safety and efficacy of dihydroartemisinin-piperaquine in falciparum malaria: A prospective multi-centre individual patient data analysis. PloS One. 2009; 4: e6358. doi: 10.1371/journal.pone.0006358
    • (2009) PloS One , vol.4 , pp. e6358
    • Zwang, J.1    Ashley, E.A.2    Karema, C.3    D'Alessandro, U.4    Smithuis, F.5    Dorsey, G.6
  • 38
    • 84877311728 scopus 로고    scopus 로고
    • Malaria transmission after artemether-lumefantrine and dihydroartemisinin-piperaquine: A randomized trial
    • Sawa P, Shekalaghe SA, Drakeley CJ, Sutherland CJ, Mweresa CK, Baidjoe AY, et al. Malaria transmission after artemether-lumefantrine and dihydroartemisinin-piperaquine: A randomized trial. J Infect Dis. 2013; 207: 1637-1645. doi: 10.1093/infdis/jit077
    • (2013) J Infect Dis , vol.207 , pp. 1637-1645
    • Sawa, P.1    Shekalaghe, S.A.2    Drakeley, C.J.3    Sutherland, C.J.4    Mweresa, C.K.5    Baidjoe, A.Y.6
  • 39
    • 85020280178 scopus 로고    scopus 로고
    • National Treatment Guidelines for Malaria in Cambodia
    • Cambodia Ministry of Health. National Treatment Guidelines for Malaria in Cambodia, December 2014.
    • (2014) Cambodia Ministry of Health December
  • 40
    • 84959075066 scopus 로고    scopus 로고
    • Combination therapies for malaria are failing-what next
    • Saunders D, Lon C. Combination therapies for malaria are failing-what next? Lancet Infect Dis. 2016; 16: 274-275. doi: 10.1016/S1473-3099(15)00525-3
    • (2016) Lancet Infect Dis , Issue.16 , pp. 274-275
    • Saunders, D.1    Lon, C.2
  • 41
    • 84926450796 scopus 로고    scopus 로고
    • Assessment of therapeutic responses to gametocytocidal drugs in Plasmodium falciparum malaria
    • White NJ, Ashley EA, Recht J, Delves MJ, Ruecker A, Smithuis FM, et al. Assessment of therapeutic responses to gametocytocidal drugs in Plasmodium falciparum malaria. Malar J. 2014; 13: 483. doi: 10. 1186/1475-2875-13-483
    • (2014) Malar J , vol.13 , pp. 483
    • White, N.J.1    Ashley, E.A.2    Recht, J.3    Delves, M.J.4    Ruecker, A.5    Smithuis, F.M.6
  • 42
    • 84926454336 scopus 로고    scopus 로고
    • Quantification of female and male Plasmodium falciparum gametocytes by reverse transcriptase quantitative PCR
    • Schneider P, Reece SE, van Schaijk BCL, Bousema T, Lanke KHW, Meaden CSJ, et al. Quantification of female and male Plasmodium falciparum gametocytes by reverse transcriptase quantitative PCR. Mol Biochem Parasitol. 2015; 199: 29-33. doi: 10.1016/j.molbiopara.2015.03.006
    • (2015) Mol Biochem Parasitol , vol.199 , pp. 29-33
    • Schneider, P.1    Reece, S.E.2    Van Schaijk, B.C.L.3    Bousema, T.4    Khw, L.5    Csj, M.6
  • 43
    • 0342755935 scopus 로고
    • Observations on the action of quinine, atebrin and plasmoquine on the gametocytes of Plasmodium falciparum
    • Mackerras MJ, Ercole QN. Observations on the action of quinine, atebrin and plasmoquine on the gametocytes of Plasmodium falciparum. Trans R Soc Trop Med Hyg. 1949; 42: 455-463.
    • (1949) Trans R Soc Trop Med Hyg , vol.42 , pp. 455-463
    • Mackerras, M.J.1    Ercole, Q.N.2
  • 44
    • 84934998246 scopus 로고    scopus 로고
    • An assessment of the supply, programmatic use, and regulatory issues of single low-dose primaquine as a Plasmodium falciparum gametocytocide for sub-Saharan Africa
    • Chen I, Poirot E, Newman M, Kandula D, Shah R, Hwang J, et al. An assessment of the supply, programmatic use, and regulatory issues of single low-dose primaquine as a Plasmodium falciparum gametocytocide for sub-Saharan Africa. Malar J. 2015; 14: 204. doi: 10.1186/s12936-015-0714-3.
    • (2015) Malar J , vol.14 , pp. 204
    • Chen, I.1    Poirot, E.2    Newman, M.3    Kandula, D.4    Shah, R.5    Hwang, J.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.