Single low dose primaquine (0.25mg/kg) does not cause clinically significant haemolysis in G6PD deficient subjects

PLoS ONE

Volumn 11, Issue 3, 2016, Pages

  Bancone, Germana ^a   Chowwiwat, Nongnud ^a   Somsakchaicharoen, Raweewan ^a   Poodpanya, Lalita ^a   Moo, Paw Khu ^a   Gornsawun, Gornpan ^a   Kajeechiwa, Ladda ^a   Thwin, May Myo ^a   Rakthinthong, Santisuk ^a   Nosten, Suphak ^a   Thinraow, Suradet ^a   Nyo, Slight Naw ^a   Ling, Clare L ^a   Wiladphaingern, Jacher ^a   Kiricharoen, Naw Lily ^a   Moore, Kerryn A ^c,d   White, Nicholas J ^b,e   Nosten, Francois ^a,e  

^a SHOKLO MALARIA RESEARCH UNIT   (Thailand)

^b MAHIDOL UNIVERSITY   (Thailand)

^c UNIVERSITY OF MELBOURNE   (Australia)

^d MACFARLANE BURNET INSTITUTE FOR MEDICAL RESEARCH AND PUBLIC HEALTH   (Australia)

^e UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

DIHYDROARTEMISININ PLUS PIPERAQUINE; GLUCOSE 6 PHOSPHATE DEHYDROGENASE; HEMOGLOBIN; PRIMAQUINE; ANTIMALARIAL AGENT;

ADOLESCENT; ADULT; ARTICLE; CHILD; CLINICAL ASSESSMENT; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIZZINESS; DOSE RESPONSE; DRUG EFFICACY; DRUG SAFETY; DRUG TOLERABILITY; ENZYME ACTIVITY; FEMALE; GENOTYPE; GLUCOSE 6 PHOSPHATE DEHYDROGENASE DEFICIENCY; HEMOGLOBIN DETERMINATION; HEMOGLOBINOPATHY; HEMOLYSIS; HUMAN; LOW DRUG DOSE; MAJOR CLINICAL STUDY; MALARIA FALCIPARUM; MALE; MIDDLE AGED; MYANMAR; PARASITE CLEARANCE; PARASITE TRANSMISSION; PHENOTYPE; PRESCHOOL CHILD; PRURITUS; SCHOOL CHILD; SIDE EFFECT; SINGLE DRUG DOSE; THAILAND; YOUNG ADULT; BLOOD; CLINICAL TRIAL; COMPLICATION; DRUG EFFECTS; INFANT; MALARIA, FALCIPARUM; PLASMODIUM FALCIPARUM;

ADULT; ANTIMALARIALS; CHILD; CHILD, PRESCHOOL; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; GLUCOSEPHOSPHATE DEHYDROGENASE DEFICIENCY; HEMOGLOBINS; HEMOLYSIS; HUMANS; INFANT; MALARIA, FALCIPARUM; MALE; MIDDLE AGED; PLASMODIUM FALCIPARUM; PRIMAQUINE; YOUNG ADULT;

EID: 84962050336     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0151898     Document Type: Article

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