Identification of Novel Cytotoxic Peptide KENPVLSLVNGMF from Marine Sponge Xestospongia testudinaria, with Characterization of Stability in Human Serum

International Journal of Peptide Research and Therapeutics

Volumn 24, Issue 1, 2018, Pages 189-199

  Quah, Yixian ^a   Mohd Ismail, Nor Ismaliza ^a   Ooi, Jillian Lean Sim ^b   Affendi, Yang Amri ^b,c   Abd Manan, Fazilah ^d   Wong, Fai Chu ^a   Chai, Tsun Thai ^a  

^a UNIVERSITI TUNKU ABDUL RAHMAN   (Malaysia)

^b UNIVERSITY OF MALAYA   (Malaysia)

^c UNIVERSITY OF MALAYA   (Malaysia)

^d UNIVERSITI TEKNOLOGI MALAYSIA   (Malaysia)

Author keywords

Cancer; Cytotoxic peptide; Marine sponge; Peptide stability; Protein hydrolysate; Xestospongia testudinaria

Indexed keywords

ANTINEOPLASTIC AGENT; FLUOROURACIL; LEUCYLLEUCYLALANYLTHREONYLISOLEUCYLPROPYLLYSYLVALYLGLYCYL VALYLPHENYLALANYLSERYLISOLEUCYLLEUCYLVALINE; LYSYLGLUTAMYLASPARAGINYLPROPYLVALYLLEUCYLSERYLLEUCYLVALYLASPARAGINYLGLYCYLMETHIONYLPHENYLALANINE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; DRUG HALF LIFE; DRUG IDENTIFICATION; DRUG POTENCY; DRUG SELECTIVITY; DRUG STABILITY; EC50; HELA CELL LINE; HUMAN; HUMAN CELL; HYDROLYSIS; IN VITRO STUDY; LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY; PROTEIN CONTENT; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; XESTOSPONGIA; XESTOSPONGIA TESTUDINARIA;

EID: 85020084459     PISSN: 15733149     EISSN: 15733904     Source Type: Journal    
DOI: 10.1007/s10989-017-9604-6     Document Type: Article

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