메뉴 건너뛰기




Volumn 8, Issue , 2017, Pages

Large scale meta-analysis characterizes genetic architecture for common psoriasis associated variants

(37)  Tsoi, Lam C a,b   Stuart, Philip E a   Tian, Chao c   Gudjonsson, Johann E a   Das, Sayantan b   Zawistowski, Matthew b   Ellinghaus, Eva d   Barker, Jonathan N e   Chandran, Vinod f,g   Dand, Nick e   Duffin, Kristina Callis h   Enerbäck, Charlotta i   Esko, Tõnu j,k   Franke, Andre d   Gladman, Dafna D f,g   Hoffmann, Per l,m   Kingo, Külli n   Kõks, Sulev o,p   Krueger, Gerald G h   Lim, Henry W q   more..


Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERFERON;

EID: 85019965749     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms15382     Document Type: Article
Times cited : (265)

References (51)
  • 2
    • 77649186719 scopus 로고    scopus 로고
    • Geoepidemiology and environmental factors of psoriasis and psoriatic arthritis
    • Chandran, V. & Raychaudhuri, S. P. Geoepidemiology and environmental factors of psoriasis and psoriatic arthritis. J. Autoimmun. 34, J314-J321 (2010).
    • (2010) J. Autoimmun , vol.34 , pp. J314-J321
    • Chandran, V.1    Raychaudhuri, S.P.2
  • 3
    • 84928577617 scopus 로고    scopus 로고
    • Genome-wide meta-analysis identifies multiple novel associations and ethnic heterogeneity of psoriasis susceptibility
    • Yin, X. et al. Genome-wide meta-analysis identifies multiple novel associations and ethnic heterogeneity of psoriasis susceptibility. Nat. Commun. 6, 6916 (2015).
    • (2015) Nat. Commun , vol.6 , pp. 6916
    • Yin, X.1
  • 4
    • 84927637587 scopus 로고    scopus 로고
    • Whole-exome SNP array identifies 15 new susceptibility loci for psoriasis
    • Zuo, X. et al. Whole-exome SNP array identifies 15 new susceptibility loci for psoriasis. Nat. Commun. 6, 6793 (2015).
    • (2015) Nat. Commun , vol.6 , pp. 6793
    • Zuo, X.1
  • 5
    • 78049343768 scopus 로고    scopus 로고
    • Genome-wide association study identifies a psoriasis susceptibility locus at TRAF3IP2
    • Ellinghaus, E. et al. Genome-wide association study identifies a psoriasis susceptibility locus at TRAF3IP2. Nat. Genet. 42, 991-995 (2010).
    • (2010) Nat. Genet , vol.42 , pp. 991-995
    • Ellinghaus, E.1
  • 6
    • 59149106117 scopus 로고    scopus 로고
    • Genome-wide scan reveals association of psoriasis with IL-23 and NF-kappaB pathways
    • Nair, R. P. et al. Genome-wide scan reveals association of psoriasis with IL-23 and NF-kappaB pathways. Nat. Genet. 41, 199-204 (2009).
    • (2009) Nat. Genet , vol.41 , pp. 199-204
    • Nair, R.P.1
  • 7
    • 78049347495 scopus 로고    scopus 로고
    • A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1
    • Strange, A. et al. A genome-wide association study identifies new psoriasis susceptibility loci and an interaction between HLA-C and ERAP1. Nat. Genet. 42, 985-990 (2010).
    • (2010) Nat. Genet , vol.42 , pp. 985-990
    • Strange, A.1
  • 8
    • 78049323656 scopus 로고    scopus 로고
    • Genome-wide association analysis identifies three psoriasis susceptibility loci
    • Stuart, P. E. et al. Genome-wide association analysis identifies three psoriasis susceptibility loci. Nat. Genet. 42, 1000-1004 (2010).
    • (2010) Nat. Genet , vol.42 , pp. 1000-1004
    • Stuart, P.E.1
  • 9
    • 84870512735 scopus 로고    scopus 로고
    • Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity
    • Tsoi, L. C. et al. Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity. Nat. Genet. 44, 1341-1348 (2012).
    • (2012) Nat. Genet , vol.44 , pp. 1341-1348
    • Tsoi, L.C.1
  • 10
    • 78049329814 scopus 로고    scopus 로고
    • Association analyses identify six new psoriasis susceptibility loci in the Chinese population
    • Sun, L. D. et al. Association analyses identify six new psoriasis susceptibility loci in the Chinese population. Nat. Genet. 42, 1005-1009 (2010).
    • (2010) Nat. Genet , vol.42 , pp. 1005-1009
    • Sun, L.D.1
  • 11
    • 84890170207 scopus 로고    scopus 로고
    • Association analyses identifying two common susceptibility loci shared by psoriasis and systemic lupus erythematosus in the Chinese Han population
    • Li, Y. et al. Association analyses identifying two common susceptibility loci shared by psoriasis and systemic lupus erythematosus in the Chinese Han population. J. Med. Genet. 50, 812-818 (2013).
    • (2013) J. Med. Genet , vol.50 , pp. 812-818
    • Li, Y.1
  • 12
    • 84904212832 scopus 로고    scopus 로고
    • Sequencing-based approach identified three new susceptibility loci for psoriasis
    • Sheng, Y. et al. Sequencing-based approach identified three new susceptibility loci for psoriasis. Nat. Commun. 5, 4331 (2014).
    • (2014) Nat. Commun , vol.5
    • Sheng, Y.1
  • 13
    • 84891372710 scopus 로고    scopus 로고
    • A large-scale screen for coding variants predisposing to psoriasis
    • Tang, H. et al. A large-scale screen for coding variants predisposing to psoriasis. Nat. Genet. 46, 45-50 (2014).
    • (2014) Nat. Genet , vol.46 , pp. 45-50
    • Tang, H.1
  • 14
    • 59149096149 scopus 로고    scopus 로고
    • Psoriasis genome-wide association study identifies susceptibility variants within LCE gene cluster at 1q21
    • Zhang, X. J. et al. Psoriasis genome-wide association study identifies susceptibility variants within LCE gene cluster at 1q21. Nat. Genet. 41, 205-210 (2009).
    • (2009) Nat. Genet , vol.41 , pp. 205-210
    • Zhang, X.J.1
  • 15
    • 84859509159 scopus 로고    scopus 로고
    • Combined analysis of genome-wide association studies for Crohn disease and psoriasis identifies seven shared susceptibility loci
    • Ellinghaus, D. et al. Combined analysis of genome-wide association studies for Crohn disease and psoriasis identifies seven shared susceptibility loci. Am. J. Hum. Genet. 90, 636-647 (2012).
    • (2012) Am. J. Hum. Genet , vol.90 , pp. 636-647
    • Ellinghaus, D.1
  • 16
    • 84923253404 scopus 로고    scopus 로고
    • Dense genotyping of immune-related susceptibility loci reveals new insights into the genetics of psoriatic arthritis
    • Bowes, J. et al. Dense genotyping of immune-related susceptibility loci reveals new insights into the genetics of psoriatic arthritis. Nat. Commun. 6, 6046 (2015).
    • (2015) Nat. Commun , vol.6
    • Bowes, J.1
  • 17
    • 84929157252 scopus 로고    scopus 로고
    • Enhanced meta-analysis and replication studies identify five new psoriasis susceptibility loci
    • Tsoi, L. C. et al. Enhanced meta-analysis and replication studies identify five new psoriasis susceptibility loci. Nat. Commun. 6, 7001 (2015).
    • (2015) Nat. Commun , vol.6
    • Tsoi, L.C.1
  • 18
    • 84952638740 scopus 로고    scopus 로고
    • Genome-wide association analysis of psoriatic arthritis and cutaneous psoriasis reveals differences in their genetic architecture
    • Stuart, P. E. et al. Genome-wide Association Analysis of Psoriatic Arthritis and Cutaneous Psoriasis Reveals Differences in Their Genetic Architecture. Am. J. Hum. Genet. 97, 816-836 (2015).
    • (2015) Am. J. Hum. Genet , vol.97 , pp. 816-836
    • Stuart, P.E.1
  • 20
    • 84946483084 scopus 로고    scopus 로고
    • The immunogenetics of Psoriasis: A comprehensive review
    • Harden, J. L., Krueger, J. G. & Bowcock, A. M. The immunogenetics of Psoriasis: a comprehensive review. J. Autoimmun. 64, 66-73 (2015).
    • (2015) J. Autoimmun , vol.64 , pp. 66-73
    • Harden, J.L.1    Krueger, J.G.2    Bowcock, A.M.3
  • 21
    • 84856478855 scopus 로고    scopus 로고
    • A linear complexity phasing method for thousands of genomes
    • Delaneau, O., Marchini, J. & Zagury, J. F. A linear complexity phasing method for thousands of genomes. Nat. Methods 9, 179-181 (2012).
    • (2012) Nat. Methods , vol.9 , pp. 179-181
    • Delaneau, O.1    Marchini, J.2    Zagury, J.F.3
  • 22
    • 84864417548 scopus 로고    scopus 로고
    • Fast and accurate genotype imputation in genome-wide association studies through pre-phasing
    • Howie, B., Fuchsberger, C., Stephens, M., Marchini, J. & Abecasis, G. R. Fast and accurate genotype imputation in genome-wide association studies through pre-phasing. Nat. Genet. 44, 955-959 (2012).
    • (2012) Nat. Genet , vol.44 , pp. 955-959
    • Howie, B.1    Fuchsberger, C.2    Stephens, M.3    Marchini, J.4    Abecasis, G.R.5
  • 23
    • 84975795680 scopus 로고    scopus 로고
    • An integrated map of genetic variation from 1,092 human genomes
    • 1000 Genomes Project Consortium et al. An integrated map of genetic variation from 1,092 human genomes. Nature 491, 56-65 (2012).
    • (2012) Nature , vol.491 , pp. 56-65
  • 24
    • 3543025789 scopus 로고    scopus 로고
    • A simple model for potential use with a misclassified binary outcome in epidemiology
    • Duffy, S. W. et al. A simple model for potential use with a misclassified binary outcome in epidemiology. J. Epidemiol. Community Health 58, 712-717 (2004).
    • (2004) J. Epidemiol. Community Health , vol.58 , pp. 712-717
    • Duffy, S.W.1
  • 25
    • 84895868643 scopus 로고    scopus 로고
    • Efficient logistic regression designs under an imperfect population identifier
    • Albert, P. S., Liu, A. & Nansel, T. Efficient logistic regression designs under an imperfect population identifier. Biometrics 70, 175-184 (2014).
    • (2014) Biometrics , vol.70 , pp. 175-184
    • Albert, P.S.1    Liu, A.2    Nansel, T.3
  • 26
    • 77955894071 scopus 로고    scopus 로고
    • METAL: Fast and efficient meta-analysis of genomewide association scans
    • Willer, C. J., Li, Y. & Abecasis, G. R. METAL: fast and efficient meta-analysis of genomewide association scans. Bioinformatics 26, 2190-2191 (2010).
    • (2010) Bioinformatics , vol.26 , pp. 2190-2191
    • Willer, C.J.1    Li, Y.2    Abecasis, G.R.3
  • 27
    • 79955860273 scopus 로고    scopus 로고
    • Random-effects model aimed at discovering associations in meta-analysis of genome-wide association studies
    • Han, B. & Eskin, E. Random-effects model aimed at discovering associations in meta-analysis of genome-wide association studies. Am. J. Hum. Genet. 88, 586-598 (2011).
    • (2011) Am. J. Hum. Genet , vol.88 , pp. 586-598
    • Han, B.1    Eskin, E.2
  • 28
    • 79960279940 scopus 로고    scopus 로고
    • Promise and pitfalls of the Immunochip
    • Cortes, A. & Brown, M. A. Promise and pitfalls of the Immunochip. Arthritis Res. Ther. 13, 101 (2011).
    • (2011) Arthritis Res. Ther , vol.13 , pp. 101
    • Cortes, A.1    Brown, M.A.2
  • 29
    • 81055145433 scopus 로고    scopus 로고
    • Distribution of allele frequencies and effect sizes and their interrelationships for common genetic susceptibility variants
    • Park, J. H. et al. Distribution of allele frequencies and effect sizes and their interrelationships for common genetic susceptibility variants. Proc. Natl Acad. Sci. USA 108, 18026-18031 (2011).
    • (2011) Proc. Natl Acad. Sci. USA , vol.108 , pp. 18026-18031
    • Park, J.H.1
  • 30
  • 31
    • 79955841697 scopus 로고    scopus 로고
    • Evaluating the heritability explained by known susceptibility variants: A survey of ten complex diseases
    • So, H. C., Gui, A. H., Cherny, S. S. & Sham, P. C. Evaluating the heritability explained by known susceptibility variants: a survey of ten complex diseases. Genet. Epidemiol. 35, 310-317 (2011).
    • (2011) Genet. Epidemiol , vol.35 , pp. 310-317
    • So, H.C.1    Gui, A.H.2    Cherny, S.S.3    Sham, P.C.4
  • 32
    • 14244260176 scopus 로고    scopus 로고
    • Psoriatic arthritis: Epidemiology, clinical features, course, and outcome
    • Gladman, D. D., Antoni, C., Mease, P., Clegg, D. O. & Nash, P. Psoriatic arthritis: epidemiology, clinical features, course, and outcome. Ann. Rheum. Dis. 64, ii14-ii17 (2005).
    • (2005) Ann. Rheum. Dis , vol.64 , pp. ii14-ii17
    • Gladman, D.D.1    Antoni, C.2    Mease, P.3    Clegg, D.O.4    Nash, P.5
  • 33
    • 0021806161 scopus 로고
    • Psoriasis of early and late onset: Characterization of two types of psoriasis vulgaris
    • Henseler, T. & Christophers, E. Psoriasis of early and late onset: characterization of two types of psoriasis vulgaris. J. Am. Acad. Dermatol. 13, 450-456 (1985).
    • (1985) J. Am. Acad. Dermatol , vol.13 , pp. 450-456
    • Henseler, T.1    Christophers, E.2
  • 34
    • 84902965916 scopus 로고    scopus 로고
    • Age at disease onset: A key factor for understanding psoriatic disease
    • Queiro, R., Tejon, P., Alonso, S. & Coto, P. Age at disease onset: a key factor for understanding psoriatic disease. Rheumatology 53, 1178-1185 (2014).
    • (2014) Rheumatology , vol.53 , pp. 1178-1185
    • Queiro, R.1    Tejon, P.2    Alonso, S.3    Coto, P.4
  • 35
    • 84927747665 scopus 로고    scopus 로고
    • Graphical algorithm for integration of genetic and biological data: Proof of principle using psoriasis as a model
    • Tsoi, L. C., Elder, J. T. & Abecasis, G. R. Graphical algorithm for integration of genetic and biological data: proof of principle using psoriasis as a model. Bioinformatics 31, 1243-1249 (2015).
    • (2015) Bioinformatics , vol.31 , pp. 1243-1249
    • Tsoi, L.C.1    Elder, J.T.2    Abecasis, G.R.3
  • 36
    • 84923326765 scopus 로고    scopus 로고
    • Genetic and epigenetic fine mapping of causal autoimmune disease variants
    • Farh, K. K. et al. Genetic and epigenetic fine mapping of causal autoimmune disease variants. Nature 518, 337-343 (2015).
    • (2015) Nature , vol.518 , pp. 337-343
    • Farh, K.K.1
  • 37
    • 84946866478 scopus 로고    scopus 로고
    • Identification of cell types, tissues and pathways affected by risk loci in psoriasis
    • Lin, Y. et al. Identification of cell types, tissues and pathways affected by risk loci in psoriasis. Mol. Genet. Genomics 291, 1005-1012 (2016).
    • (2016) Mol. Genet. Genomics , vol.291 , pp. 1005-1012
    • Lin, Y.1
  • 38
    • 84977766689 scopus 로고    scopus 로고
    • Genome-wide pathway analysis identifies genetic pathways associated with Psoriasis
    • Aterido, A. et al. Genome-wide pathway analysis identifies genetic pathways associated with Psoriasis. J. Invest. Dermatol. 136, 593-602 (2016).
    • (2016) J. Invest. Dermatol , vol.136 , pp. 593-602
    • Aterido, A.1
  • 39
    • 84891767304 scopus 로고    scopus 로고
    • DrugBank 4.0: Shedding new light on drug metabolism
    • Law, V. et al. DrugBank 4.0: shedding new light on drug metabolism. Nucleic Acids Res. 42, D1091-D1097 (2014).
    • (2014) Nucleic Acids Res , vol.42 , pp. D1091-D1097
    • Law, V.1
  • 40
    • 84866611528 scopus 로고    scopus 로고
    • Pharmacogenomics knowledge for personalized medicine
    • Whirl-Carrillo, M. et al. Pharmacogenomics knowledge for personalized medicine. Clin. Pharmacol. Ther. 92, 414-417 (2012).
    • (2012) Clin. Pharmacol. Ther , vol.92 , pp. 414-417
    • Whirl-Carrillo, M.1
  • 42
  • 43
    • 0025304642 scopus 로고
    • Sulfasalazine improves psoriasis A double-blind analysis
    • Gupta, A. K. et al. Sulfasalazine improves psoriasis. A double-blind analysis. Arch. Dermatol. 126, 487-493 (1990).
    • (1990) Arch. Dermatol , vol.126 , pp. 487-493
    • Gupta, A.K.1
  • 44
    • 84890107642 scopus 로고    scopus 로고
    • Systematic comparison of phenome-wide association study of electronic medical record data and genome-wide association study data
    • Denny, J. C. et al. Systematic comparison of phenome-wide association study of electronic medical record data and genome-wide association study data. Nat. Biotechnol. 31, 1102-1110 (2013).
    • (2013) Nat. Biotechnol , vol.31 , pp. 1102-1110
    • Denny, J.C.1
  • 45
    • 84928786973 scopus 로고    scopus 로고
    • A weighted polygenic risk score using 14 known susceptibility variants to estimate risk and age onset of psoriasis in Han Chinese
    • Yin, X. et al. A weighted polygenic risk score using 14 known susceptibility variants to estimate risk and age onset of psoriasis in Han Chinese. PLoS ONE 10, e0125369 (2015).
    • (2015) PLoS ONE , vol.10 , pp. e0125369
    • Yin, X.1
  • 46
    • 79955769482 scopus 로고    scopus 로고
    • A genetic risk score combining ten psoriasis risk loci improves disease prediction
    • Chen, H. et al. A genetic risk score combining ten psoriasis risk loci improves disease prediction. PLoS ONE 6, e19454 (2011).
    • (2011) PLoS ONE , vol.6 , pp. e19454
    • Chen, H.1
  • 47
    • 33645023965 scopus 로고    scopus 로고
    • Distinct clinical differences between HLA-Cw0602 positive and negative psoriasis patients-an analysis of 1019 HLA-C-and HLA-B-typed patients
    • Gudjonsson, J. E. et al. Distinct clinical differences between HLA-Cw0602 positive and negative psoriasis patients-an analysis of 1019 HLA-C-and HLA-B-typed patients. J. Invest. Dermatol. 126, 740-745 (2006).
    • (2006) J. Invest. Dermatol , vol.126 , pp. 740-745
    • Gudjonsson, J.E.1
  • 48
    • 70349910628 scopus 로고    scopus 로고
    • Genetic determinants of pediatric inflammatory bowel disease: Is age of onset genetically determined?
    • Scherr, R., Essers, J., Hakonarson, H. & Kugathasan, S. Genetic determinants of pediatric inflammatory bowel disease: is age of onset genetically determined? Dig. Dis. 27, 236-239 (2009).
    • (2009) Dig. Dis , vol.27 , pp. 236-239
    • Scherr, R.1    Essers, J.2    Hakonarson, H.3    Kugathasan, S.4
  • 49
    • 84985920199 scopus 로고    scopus 로고
    • Inverse correlation of genetic risk score with age at onset in bout-onset and progressive-onset multiple sclerosis
    • Sorosina, M. et al. Inverse correlation of genetic risk score with age at onset in bout-onset and progressive-onset multiple sclerosis. Mult. Scler. 21, 1463-1467 (2014).
    • (2014) Mult. Scler , vol.21 , pp. 1463-1467
    • Sorosina, M.1
  • 50
    • 84872620069 scopus 로고    scopus 로고
    • Global epidemiology of psoriasis: A systematic review of incidence and prevalence
    • Parisi, R., Symmons, D. P., Griffiths, C. E. & Ashcroft, D. M. Global epidemiology of psoriasis: a systematic review of incidence and prevalence. J. Invest. Dermatol. 133, 377-385 (2012).
    • (2012) J. Invest. Dermatol , vol.133 , pp. 377-385
    • Parisi, R.1    Symmons, D.P.2    Griffiths, C.E.3    Ashcroft, D.M.4
  • 51
    • 84941145210 scopus 로고    scopus 로고
    • The BioGRID interaction database: 2015 update
    • Chatr-Aryamontri, A. et al. The BioGRID interaction database: 2015 update. Nucleic Acids Res. 43, D470-D478 (2015).
    • (2015) Nucleic Acids Res , vol.43 , pp. D470-D478
    • Chatr-Aryamontri, A.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.