A weighted polygenic risk score using 14 known susceptibility variants to estimate risk and age onset of psoriasis in Han Chinese

PLoS ONE

Volumn 10, Issue 5, 2015, Pages

  Yin, Xianyong ^a,b,d,e,f   Cheng, Hui ^a,b   Lin, Yan ^a,b   Wineinger, Nathan E ^c,d   Zhou, Fusheng ^a,b   Sheng, Yujun ^a,b   Yang, Chao ^a,b   Li, Pan ^a,b   Li, Feng ^a,b   Shen, Changbing ^a,b   Yang, Sen ^a,b   Schork, Nicholas J ^f   Zhang, Xuejun ^a,b  

^a ANHUI MEDICAL UNIVERSITY   (China)

^b Key Lab of Gene Resource Utilization for Complex Diseases   (China)

^c SCRIPPS HEALTH   (United States)

^d SCRIPPS TRANSLATIONAL SCIENCE INSTITUTE   (United States)

^e SCRIPPS RESEARCH INSTITUTE   (United States)

^f J CRAIG VENTER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADOLESCENT; ADULT; AGED; ARTICLE; CHILD; CONTROLLED STUDY; DISCRIMINANT ANALYSIS; FEMALE; GENE LOCUS; GENETIC ASSOCIATION; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; GENOTYPE; HAN CHINESE; HIGH RISK PATIENT; HUMAN; MAJOR CLINICAL STUDY; MALE; MULTIFACTORIAL INHERITANCE; PRESCHOOL CHILD; PSORIASIS; SCHOOL CHILD; SINGLE NUCLEOTIDE POLYMORPHISM; VERY ELDERLY; AREA UNDER THE CURVE; BIOLOGICAL MODEL; CASE CONTROL STUDY; CHINA; DRINKING BEHAVIOR; GENETIC PREDISPOSITION; GENETICS; GENOME-WIDE ASSOCIATION STUDY; MIDDLE AGED; ONSET AGE; PATHOPHYSIOLOGY; PROPORTIONAL HAZARDS MODEL; RISK FACTOR;

ADOLESCENT; ADULT; AGE OF ONSET; AGED; AGED, 80 AND OVER; ALCOHOL DRINKING; AREA UNDER CURVE; CASE-CONTROL STUDIES; CHILD; CHILD, PRESCHOOL; CHINA; FEMALE; GENETIC LOCI; GENETIC PREDISPOSITION TO DISEASE; GENOME-WIDE ASSOCIATION STUDY; HUMANS; MALE; MIDDLE AGED; MODELS, GENETIC; POLYMORPHISM, SINGLE NUCLEOTIDE; PROPORTIONAL HAZARDS MODELS; PSORIASIS; RISK FACTORS;

EID: 84928786973     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0125369     Document Type: Article

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