Exercise and BDNF reduce Aβ production by enhancing α-secretase processing of APP

Journal of Neurochemistry

Volumn 142, Issue 2, 2017, Pages 286-296

  Nigam, Saket M ^a,b   Xu, Shaohua ^a   Kritikou, Joanna S ^a   Marosi, Krisztina ^b   Brodin, Lennart ^a   Mattson, Mark P ^b  

^a KAROLINSKA INSTITUTE   (Sweden)

^b NATIONAL INSTITUTE ON AGING   (United States)

Author keywords

alpha secretase; Alzheimer's disease; amyloid precursor protein; BDNF; exercise

Indexed keywords

ALPHA SECRETASE; AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; BRAIN DERIVED NEUROTROPHIC FACTOR; ASPARTIC PROTEINASE; SECRETASE;

ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME BINDING; ENZYME INHIBITION; ENZYME LOCALIZATION; EXERCISE; HUMAN; HUMAN CELL; MALE; MOUSE; NEURITE OUTGROWTH; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN SYNTHESIS; SIGNAL TRANSDUCTION; ANIMAL; BIOSYNTHESIS; BRAIN; DISEASE MODEL; METABOLISM; PHYSIOLOGY; TRANSGENIC MOUSE;

ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; ASPARTIC ACID ENDOPEPTIDASES; BRAIN; BRAIN-DERIVED NEUROTROPHIC FACTOR; DISEASE MODELS, ANIMAL; MICE, TRANSGENIC; PHYSICAL CONDITIONING, ANIMAL; SIGNAL TRANSDUCTION;

EID: 85019834826     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/jnc.14034     Document Type: Article

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