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Volumn 292, Issue 21, 2017, Pages 8569-8576

Glucuronides in the gut: Sugar-driven symbioses between microbe and host

Author keywords

[No Author keywords available]

Indexed keywords

CARBON; GLUCOSE; MAMMALS; MICROORGANISMS; PLANTS (BOTANY); PROTEINS;

EID: 85019765671     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.R116.767434     Document Type: Article
Times cited : (161)

References (91)
  • 1
    • 0022463534 scopus 로고
    • In situ bacterial metabolism and colon mutagens
    • Goldin, B. R. (1986) In situ bacterial metabolism and colon mutagens. Annu. Rev. Microbiol. 40, 367-393
    • (1986) Annu. Rev. Microbiol. , vol.40 , pp. 367-393
    • Goldin, B.R.1
  • 2
    • 0017192270 scopus 로고
    • The relationship between diet and rat fecal bacterial enzymes implicated in colon cancer
    • Goldin, B. R., and Gorbach, S. L. (1976) The relationship between diet and rat fecal bacterial enzymes implicated in colon cancer. J. Natl. Cancer Inst. 57, 371-375
    • (1976) J. Natl. Cancer Inst. , vol.57 , pp. 371-375
    • Goldin, B.R.1    Gorbach, S.L.2
  • 3
    • 0018182404 scopus 로고
    • Metabolism of androgens and estrogens by human fecal microorganisms
    • Lombardi, P., Goldin, B., Boutin, E., and Gorbach, S. L. (1978) Metabolism of androgens and estrogens by human fecal microorganisms. J. Steroid Biochem. 9, 795-801
    • (1978) J. Steroid Biochem. , vol.9 , pp. 795-801
    • Lombardi, P.1    Goldin, B.2    Boutin, E.3    Gorbach, S.L.4
  • 4
    • 0023505288 scopus 로고
    • Bacterial metabolism of natural and synthetic sex hormones undergoing enterohepatic circulation
    • Winter, J., and Bokkenheuser, V. D. (1987) Bacterial metabolism of natural and synthetic sex hormones undergoing enterohepatic circulation. J. Steroid Biochem. 27, 1145-1149
    • (1987) J. Steroid Biochem. , vol.27 , pp. 1145-1149
    • Winter, J.1    Bokkenheuser, V.D.2
  • 6
    • 0035748644 scopus 로고    scopus 로고
    • Intestinal bacterial β-glucuronidase activity of patients with colon cancer
    • Kim, D. H., and Jin, Y. H. (2001) Intestinal bacterial β-glucuronidase activity of patients with colon cancer. Arch. Pharm. Res. 24, 564-567
    • (2001) Arch. Pharm. Res. , vol.24 , pp. 564-567
    • Kim, D.H.1    Jin, Y.H.2
  • 7
    • 84890285742 scopus 로고    scopus 로고
    • Androgen glucuronidation: An unexpected target for androgen deprivation therapy, with prognosis and diagnostic implications
    • Grosse, L., Pâquet, S., Caron, P., Fazli, L., Rennie, P. S., Bélanger, A., and Barbier, O. (2013) Androgen glucuronidation: an unexpected target for androgen deprivation therapy, with prognosis and diagnostic implications. Cancer Res. 73, 6963-6971
    • (2013) Cancer Res. , vol.73 , pp. 6963-6971
    • Grosse, L.1    Pâquet, S.2    Caron, P.3    Fazli, L.4    Rennie, P.S.5    Bélanger, A.6    Barbier, O.7
  • 8
    • 84962251830 scopus 로고    scopus 로고
    • Three measurable and modifiable enteric microbial biotransformations relevant to cancer prevention and treatment
    • Plotnikoff, G. A. (2014) Three measurable and modifiable enteric microbial biotransformations relevant to cancer prevention and treatment. Glob. Adv. Health Med. 3, 33-43
    • (2014) Glob. Adv. Health Med. , vol.3 , pp. 33-43
    • Plotnikoff, G.A.1
  • 9
    • 84959020691 scopus 로고    scopus 로고
    • Unique β-glucuronidase locus in gut microbiomes of Crohn's disease patients and unaffected first-degree relatives
    • Gloux, K., and Anba-Mondoloni, J. (2016) Unique β-glucuronidase locus in gut microbiomes of Crohn's disease patients and unaffected first-degree relatives. PLoS ONE 11, e0148291
    • (2016) PLoS ONE , vol.11 , pp. e0148291
    • Gloux, K.1    Anba-Mondoloni, J.2
  • 12
    • 0032464663 scopus 로고    scopus 로고
    • What's for dinner?: Entner-Doudoroff metabolism in Escherichia coli
    • Peekhaus, N., and Conway, T. (1998) What's for dinner?: Entner-Doudoroff metabolism in Escherichia coli. J. Bacteriol. 180, 3495-3502
    • (1998) J. Bacteriol. , vol.180 , pp. 3495-3502
    • Peekhaus, N.1    Conway, T.2
  • 13
    • 0029878731 scopus 로고    scopus 로고
    • Structure of human β-glucuronidase reveals candidate lysosomal targeting and active-site motifs
    • Jain, S., Drendel, W. B., Chen, Z. W., Mathews, F. S., Sly, W. S., and Grubb, J. H. (1996) Structure of human β-glucuronidase reveals candidate lysosomal targeting and active-site motifs. Nat. Struct. Biol. 3, 375-381
    • (1996) Nat. Struct. Biol. , vol.3 , pp. 375-381
    • Jain, S.1    Drendel, W.B.2    Chen, Z.W.3    Mathews, F.S.4    Sly, W.S.5    Grubb, J.H.6
  • 14
    • 0015582263 scopus 로고
    • β-Glucuronidase deficiency: Report of clinical, radiologic, and biochemical features of a new mucopolysaccharidosis
    • Sly, W. S., Quinton, B. A., McAlister, W. H., and Rimoin, D. L. (1973) β-Glucuronidase deficiency: report of clinical, radiologic, and biochemical features of a new mucopolysaccharidosis. J. Pediatr. 82, 249-257
    • (1973) J. Pediatr. , vol.82 , pp. 249-257
    • Sly, W.S.1    Quinton, B.A.2    McAlister, W.H.3    Rimoin, D.L.4
  • 15
    • 0030751284 scopus 로고    scopus 로고
    • The role of β-glucuronidase in drug disposition and drug targeting in humans
    • Sperker, B., Backman, J. T., and Kroemer, H. K. (1997) The role of β-glucuronidase in drug disposition and drug targeting in humans. Clin. Pharmacokinet. 33, 18-31
    • (1997) Clin. Pharmacokinet. , vol.33 , pp. 18-31
    • Sperker, B.1    Backman, J.T.2    Kroemer, H.K.3
  • 17
    • 0036349377 scopus 로고    scopus 로고
    • Enterohepatic circulation: Physiological, pharmacokinetic and clinical implications
    • Roberts, M. S., Magnusson, B. M., Burczynski, F. J., and Weiss, M. (2002) Enterohepatic circulation: physiological, pharmacokinetic and clinical implications. Clin. Pharmacokinet. 41, 751-790
    • (2002) Clin. Pharmacokinet. , vol.41 , pp. 751-790
    • Roberts, M.S.1    Magnusson, B.M.2    Burczynski, F.J.3    Weiss, M.4
  • 18
    • 0042834374 scopus 로고    scopus 로고
    • Enterohepatic cycling of bilirubin as a cause of "black" pigment gallstones in adult life
    • Vítek, L., and Carey, M. C. (2003) Enterohepatic cycling of bilirubin as a cause of "black" pigment gallstones in adult life. Eur. J. Clin. Invest. 33, 799-810
    • (2003) Eur. J. Clin. Invest. , vol.33 , pp. 799-810
    • Vítek, L.1    Carey, M.C.2
  • 19
    • 0020687446 scopus 로고
    • Analysis of bilirubins in biological fluids by extraction and thin-layer chromatography of the intact tetrapyrroles: Application to bile of patients with Gilbert's syndrome, hemolysis, or cholelithiasis
    • Fevery, J., Blanckaert, N., Leroy, P., Michiels, R., and Heirwegh, K. P. (1983) Analysis of bilirubins in biological fluids by extraction and thin-layer chromatography of the intact tetrapyrroles: application to bile of patients with Gilbert's syndrome, hemolysis, or cholelithiasis. Hepatology 3, 177-183
    • (1983) Hepatology , vol.3 , pp. 177-183
    • Fevery, J.1    Blanckaert, N.2    Leroy, P.3    Michiels, R.4    Heirwegh, K.P.5
  • 20
    • 0038541723 scopus 로고    scopus 로고
    • Intestinal colonization leading to fecal urobilinoid excretion may play a role in the pathogenesis of neonatal jaundice
    • Vítek, L., Kotal, P., Jirsa, M., Malina, J., Cerná, M., Chmelar, D., and Fevery, J. (2000) Intestinal colonization leading to fecal urobilinoid excretion may play a role in the pathogenesis of neonatal jaundice. J. Pediatr. Gastroenterol. Nutr. 30, 294-298
    • (2000) J. Pediatr. Gastroenterol. Nutr. , vol.30 , pp. 294-298
    • Vítek, L.1    Kotal, P.2    Jirsa, M.3    Malina, J.4    Cerná, M.5    Chmelar, D.6    Fevery, J.7
  • 21
    • 0023132858 scopus 로고
    • Bilirubin is an antioxidant of possible physiological importance
    • Stocker, R., Yamamoto, Y., McDonagh, A. F., Glazer, A. N., and Ames, B. N. (1987) Bilirubin is an antioxidant of possible physiological importance. Science. 235, 1043-1046
    • (1987) Science. , vol.235 , pp. 1043-1046
    • Stocker, R.1    Yamamoto, Y.2    McDonagh, A.F.3    Glazer, A.N.4    Ames, B.N.5
  • 22
    • 70449389954 scopus 로고    scopus 로고
    • Bilirubin chemistry and metabolism; Harmful and protective aspects
    • Vítek, L., and Ostrow, J. D. (2009) Bilirubin chemistry and metabolism; harmful and protective aspects. Curr. Pharm. Des. 15, 2869-2883
    • (2009) Curr. Pharm. Des. , vol.15 , pp. 2869-2883
    • Vítek, L.1    Ostrow, J.D.2
  • 23
    • 0013933084 scopus 로고
    • Pathogenesis of calcium bilirubinate gallstone: Role of E. Coli, β-glucuronidase and coagulation by inorganic ions, polyelectrolytes and agitation
    • Maki, T. (1966) Pathogenesis of calcium bilirubinate gallstone: role of E. coli, β-glucuronidase and coagulation by inorganic ions, polyelectrolytes and agitation. Ann. Surg. 164, 90-100
    • (1966) Ann. Surg. , vol.164 , pp. 90-100
    • Maki, T.1
  • 24
    • 84948988340 scopus 로고    scopus 로고
    • Metagenomic sequencing of bile from gallstone patients to identify different microbial community patterns and novel biliary bacteria
    • Shen, H., Ye, F., Xie, L., Yang, J., Li, Z., Xu, P., Meng, F., Li, L., Chen, Y., Bo, X., Ni, M., and Zhang, X. (2015) Metagenomic sequencing of bile from gallstone patients to identify different microbial community patterns and novel biliary bacteria. Sci. Rep. 5, 17450
    • (2015) Sci. Rep. , vol.5 , pp. 17450
    • Shen, H.1    Ye, F.2    Xie, L.3    Yang, J.4    Li, Z.5    Xu, P.6    Meng, F.7    Li, L.8    Chen, Y.9    Bo, X.10    Ni, M.11    Zhang, X.12
  • 25
    • 84961188199 scopus 로고    scopus 로고
    • Influence of the biliary system on biliary bacteria revealed by bacterial communities of the human biliary and upper digestive tracts
    • Ye, F., Shen, H., Li, Z., Meng, F., Li, L., Yang, J., Chen, Y., Bo, X., Zhang, X., and Ni, M. (2016) Influence of the biliary system on biliary bacteria revealed by bacterial communities of the human biliary and upper digestive tracts. PLoS ONE 11, e0150519
    • (2016) PLoS ONE , vol.11 , pp. e0150519
    • Ye, F.1    Shen, H.2    Li, Z.3    Meng, F.4    Li, L.5    Yang, J.6    Chen, Y.7    Bo, X.8    Zhang, X.9    Ni, M.10
  • 27
    • 0017355635 scopus 로고
    • Hydrolysis of steroid glucuronides with β-glucuronidase preparations from bovine liver, helix pomatia, and E. Coli
    • Graef, V., Furuya, E., and Nishikaze, O. (1977) Hydrolysis of steroid glucuronides with β-glucuronidase preparations from bovine liver, helix pomatia, and E. coli. Clin. Chem. 23, 532-535
    • (1977) Clin. Chem. , vol.23 , pp. 532-535
    • Graef, V.1    Furuya, E.2    Nishikaze, O.3
  • 28
    • 0034305538 scopus 로고    scopus 로고
    • Enterohepatic recycling of estrogen and its relevance with female fertility
    • Sher, A., and Rahman, M. A. (2000) Enterohepatic recycling of estrogen and its relevance with female fertility. Arch. Pharm. Res. 23, 513-517
    • (2000) Arch. Pharm. Res. , vol.23 , pp. 513-517
    • Sher, A.1    Rahman, M.A.2
  • 29
    • 0014147104 scopus 로고
    • Biliary excretion and enterohepatic circulation of estrone and estriol in rodents
    • Sandberg, A. A., Kirdani, R. Y., Back, N., Weyman, P., and Slaunwhite, W. R. (1967) Biliary excretion and enterohepatic circulation of estrone and estriol in rodents. Am. J. Physiol. 213, 1138-1142
    • (1967) Am. J. Physiol. , vol.213 , pp. 1138-1142
    • Sandberg, A.A.1    Kirdani, R.Y.2    Back, N.3    Weyman, P.4    Slaunwhite, W.R.5
  • 30
    • 84992313177 scopus 로고    scopus 로고
    • The intestinal microbiome and estrogen receptor-positive female breast cancer
    • Kwa, M., Plottel, C. S., Blaser, M. J., and Adams, S. (2016) The intestinal microbiome and estrogen receptor-positive female breast cancer. J. Natl. Cancer Inst. 108, 1-10
    • (2016) J. Natl. Cancer Inst. , vol.108 , pp. 1-10
    • Kwa, M.1    Plottel, C.S.2    Blaser, M.J.3    Adams, S.4
  • 32
    • 4244154650 scopus 로고
    • Glucuronide formation in the transport of testosterone and androstenedione by rat intestine
    • Kreek, M. J., Guggenheim, F. G., Ross, J. E., and Tapley, D. F. (1963) Glucuronide formation in the transport of testosterone and androstenedione by rat intestine. Biochim. Biophys. Acta 74, 418-427
    • (1963) Biochim. Biophys. Acta , vol.74 , pp. 418-427
    • Kreek, M.J.1    Guggenheim, F.G.2    Ross, J.E.3    Tapley, D.F.4
  • 33
    • 34548092212 scopus 로고    scopus 로고
    • Glucuronidation of thyroxine in human liver, jejunum, and kidney microsomes
    • Yamanaka, H., Nakajima, M., Katoh, M., and Yokoi, T. (2007) Glucuronidation of thyroxine in human liver, jejunum, and kidney microsomes. Drug Metab. Dispos. 35, 1642-1648
    • (2007) Drug Metab. Dispos. , vol.35 , pp. 1642-1648
    • Yamanaka, H.1    Nakajima, M.2    Katoh, M.3    Yokoi, T.4
  • 34
    • 0023953234 scopus 로고
    • Hydrolysis of iodothyronine conjugates by intestinal bacteria
    • Hazenberg, M. P., de Herder, W. W., and Visser, T. J. (1988) Hydrolysis of iodothyronine conjugates by intestinal bacteria. FEMS Microbiol. Rev. 4, 9-16
    • (1988) FEMS Microbiol. Rev. , vol.4 , pp. 9-16
    • Hazenberg, M.P.1    De Herder, W.W.2    Visser, T.J.3
  • 35
    • 0027215403 scopus 로고
    • Binding and degradation of 3,5,3 β-triiodothyronine and thyroxine by rat intestinal bacteria
    • DiStefano, J. J., 3rd., de Luze, A., and Nguyen, T. T. (1993) Binding and degradation of 3,5,3 β-triiodothyronine and thyroxine by rat intestinal bacteria. Am. J. Physiol. 264, E966-E972
    • (1993) Am. J. Physiol. , vol.264 , pp. E966-E972
    • DiStefano, J.J.1    De Luze, A.2    Nguyen, T.T.3
  • 36
    • 0033859843 scopus 로고    scopus 로고
    • The mechanism of action of thyroid hormones
    • Zhang, J., and Lazar, M. (2000) The mechanism of action of thyroid hormones. Annu. Rev. Physiol. 62, 439-66
    • (2000) Annu. Rev. Physiol. , vol.62 , pp. 439-466
    • Zhang, J.1    Lazar, M.2
  • 38
    • 0027502118 scopus 로고
    • Stimulation of mucosal alkaline secretion in rat duodenum by dopamine and dopaminergic compounds
    • Flemström, G., Säfsten, B., and Jedstedt, G. (1993) Stimulation of mucosal alkaline secretion in rat duodenum by dopamine and dopaminergic compounds. Gastroenterology. 104, 825-833
    • (1993) Gastroenterology. , vol.104 , pp. 825-833
    • Flemström, G.1    Säfsten, B.2    Jedstedt, G.3
  • 39
    • 0028037533 scopus 로고
    • Inhibition of gastrointestinal motility by MPTP via adrenergic and dopaminergic mechanisms
    • Haskel, Y., and Hanani, M. (1994) Inhibition of gastrointestinal motility by MPTP via adrenergic and dopaminergic mechanisms. Dig. Dis. Sci. 39, 2364-2367
    • (1994) Dig. Dis. Sci. , vol.39 , pp. 2364-2367
    • Haskel, Y.1    Hanani, M.2
  • 40
    • 0037324354 scopus 로고    scopus 로고
    • Serotonin (5-hydroxytryptamine) glucuronidation in vitro: Assay development, human liver microsome activities and species differences
    • Krishnaswamy, S., Duan, S. X., Von Moltke, L. L., Greenblatt, D. J., Sudmeier, J. L., Bachovchin, W. W., and Court, M. H. (2003) Serotonin (5-hydroxytryptamine) glucuronidation in vitro: assay development, human liver microsome activities and species differences. Xenobiotica 33, 169-180
    • (2003) Xenobiotica , vol.33 , pp. 169-180
    • Krishnaswamy, S.1    Duan, S.X.2    Von Moltke, L.L.3    Greenblatt, D.J.4    Sudmeier, J.L.5    Bachovchin, W.W.6    Court, M.H.7
  • 42
    • 63849295015 scopus 로고    scopus 로고
    • The enterohepatic circulation of bile acids in mammals: Form and functions
    • Hofmann, A. F. (2009) The enterohepatic circulation of bile acids in mammals: form and functions. Front. Biosci. 14, 2584-2598
    • (2009) Front. Biosci. , vol.14 , pp. 2584-2598
    • Hofmann, A.F.1
  • 43
    • 84939567798 scopus 로고    scopus 로고
    • A biosynthetic pathway for a prominent class of microbiota-derived bile acids
    • Devlin, A. S., and Fischbach, M. A. (2015) A biosynthetic pathway for a prominent class of microbiota-derived bile acids. Nat. Chem. Biol. 11, 685-690
    • (2015) Nat. Chem. Biol. , vol.11 , pp. 685-690
    • Devlin, A.S.1    Fischbach, M.A.2
  • 44
    • 0021134465 scopus 로고
    • Hepatic and extrahepatic glucuronidation of bile acids in man. Characterization of bile acid uridine 5′-diphosphate-glucuronosyltransferase in hepatic, renal, and intestinal microsomes
    • Matern, S., Matern, H., Farthmann, E. H., and Gerok, W. (1984) Hepatic and extrahepatic glucuronidation of bile acids in man. Characterization of bile acid uridine 5′-diphosphate-glucuronosyltransferase in hepatic, renal, and intestinal microsomes. J. Clin. Invest. 74, 402-410
    • (1984) J. Clin. Invest. , vol.74 , pp. 402-410
    • Matern, S.1    Matern, H.2    Farthmann, E.H.3    Gerok, W.4
  • 45
    • 0019307242 scopus 로고
    • Analysis of bile acid glucuronides in urine. Identification of 3α,6α,12α-trihydroxy-5β-cholanoic acid
    • Almé, B., and Sjövall, J. (1980) Analysis of bile acid glucuronides in urine. identification of 3α,6α,12α-trihydroxy-5β-cholanoic acid. J. Steroid Biochem. 13, 907-916
    • (1980) J. Steroid Biochem. , vol.13 , pp. 907-916
    • Almé, B.1    Sjövall, J.2
  • 46
    • 80054121197 scopus 로고    scopus 로고
    • Fatty acids as biocompounds: Their role in human metabolism, health and disease - A review. Part 2: Fatty acid physiological roles and applications in human health and disease
    • Kremmyda, L.-S., Tvrzicka, E., Stankova, B., and Zak, A. (2011) Fatty acids as biocompounds: their role in human metabolism, health and disease-a review. Part 2: fatty acid physiological roles and applications in human health and disease. Biomed. Pap. Med. Fac. Univ. Palacky Olomouc Czech Repub. 155, 195-218
    • (2011) Biomed. Pap. Med. Fac. Univ. Palacky Olomouc Czech Repub. , vol.155 , pp. 195-218
    • Kremmyda, L.-S.1    Tvrzicka, E.2    Stankova, B.3    Zak, A.4
  • 47
  • 48
    • 0022462239 scopus 로고
    • Retinoyl β-glucuronide: An endogenous compound of human blood
    • Barua, A. B., and Olson, J. A. (1986) Retinoyl β-glucuronide: an endogenous compound of human blood. Am. J. Clin. Nutr. 43, 481-485
    • (1986) Am. J. Clin. Nutr. , vol.43 , pp. 481-485
    • Barua, A.B.1    Olson, J.A.2
  • 49
    • 4644315738 scopus 로고    scopus 로고
    • Glucuronidation of oxidized fatty acids and prostaglandins B1 and E2 by human hepatic and recombinant UDP-glucuronosyltransferases
    • Little, J. M., Kurkela, M., Sonka, J., Jäntti, S., Ketola, R., Bratton, S., Finel, M., and Radominska-Pandya, A. (2004) Glucuronidation of oxidized fatty acids and prostaglandins B1 and E2 by human hepatic and recombinant UDP-glucuronosyltransferases. J. Lipid Res. 45, 1694-1703
    • (2004) J. Lipid Res. , vol.45 , pp. 1694-1703
    • Little, J.M.1    Kurkela, M.2    Sonka, J.3    Jäntti, S.4    Ketola, R.5    Bratton, S.6    Finel, M.7    Radominska-Pandya, A.8
  • 50
    • 0018946314 scopus 로고
    • Cellular location of enzymes involved in chondroitin sulfate breakdown by Bacteroides thetaiotaomicron
    • Salyers, A. A., and O'Brien, M. (1980) Cellular location of enzymes involved in chondroitin sulfate breakdown by Bacteroides thetaiotaomicron. J. Bacteriol. 143, 772-780
    • (1980) J. Bacteriol. , vol.143 , pp. 772-780
    • Salyers, A.A.1    O'Brien, M.2
  • 52
    • 33749034730 scopus 로고    scopus 로고
    • Topoisomerase i inhibitors: Camptothecins and beyond
    • Pommier, Y. (2006) Topoisomerase I inhibitors: camptothecins and beyond. Nat. Rev. Cancer 6, 789-802
    • (2006) Nat. Rev. Cancer , vol.6 , pp. 789-802
    • Pommier, Y.1
  • 54
    • 0031736659 scopus 로고    scopus 로고
    • Pharmacology of irinotecan
    • Robert, J., and Rivory, L. (1998) Pharmacology of irinotecan. Drugs Today 34, 777-803
    • (1998) Drugs Today , vol.34 , pp. 777-803
    • Robert, J.1    Rivory, L.2
  • 58
    • 84888167989 scopus 로고    scopus 로고
    • Profile of panobinostat and its potential for treatment in solid tumors: An update
    • Anne, M., Sammartino, D., Barginear, M. F., and Budman, D. (2013) Profile of panobinostat and its potential for treatment in solid tumors: an update. Onco. Targets. Ther. 6, 1613-1624
    • (2013) Onco. Targets. Ther. , vol.6 , pp. 1613-1624
    • Anne, M.1    Sammartino, D.2    Barginear, M.F.3    Budman, D.4
  • 61
    • 84859987078 scopus 로고    scopus 로고
    • Pharmacologic targeting of bacterial β-glucuronidase alleviates nonsteroidal anti-inflammatory drug-induced enteropathy in mice
    • LoGuidice, A., Wallace, B. D., Bendel, L., Redinbo, M. R., and Boelsterli, U. A. (2012) Pharmacologic targeting of bacterial β-glucuronidase alleviates nonsteroidal anti-inflammatory drug-induced enteropathy in mice. J. Pharmacol. Exp. Ther. 341, 447-454
    • (2012) J. Pharmacol. Exp. Ther. , vol.341 , pp. 447-454
    • LoGuidice, A.1    Wallace, B.D.2    Bendel, L.3    Redinbo, M.R.4    Boelsterli, U.A.5
  • 62
    • 84890452868 scopus 로고    scopus 로고
    • Bacterial β-glucuronidase inhibition protects mice against enteropathy induced by indomethacin, ketoprofen or diclofenac: Mode of action and pharmacokinetics
    • Saitta, K. S., Zhang, C., Lee, K. K., Fujimoto, K., Redinbo, M. R., and Boelsterli, U. A. (2014) Bacterial β-glucuronidase inhibition protects mice against enteropathy induced by indomethacin, ketoprofen or diclofenac: mode of action and pharmacokinetics. Xenobiotica 44, 28-35
    • (2014) Xenobiotica , vol.44 , pp. 28-35
    • Saitta, K.S.1    Zhang, C.2    Lee, K.K.3    Fujimoto, K.4    Redinbo, M.R.5    Boelsterli, U.A.6
  • 64
    • 84873854068 scopus 로고    scopus 로고
    • Multiple NSAIDinduced hits injure the small intestine: Underlying mechanisms and novel strategies
    • Boelsterli, U. A., Redinbo, M. R., and Saitta, K. S. (2013) Multiple NSAIDinduced hits injure the small intestine: underlying mechanisms and novel strategies. Toxicol. Sci. 131, 654-667
    • (2013) Toxicol. Sci. , vol.131 , pp. 654-667
    • Boelsterli, U.A.1    Redinbo, M.R.2    Saitta, K.S.3
  • 65
    • 56249138667 scopus 로고    scopus 로고
    • Rodent models of colon carcinogenesis for the study of chemopreventive activity of natural products
    • Femia, A. P., and Caderni, G. (2008) Rodent models of colon carcinogenesis for the study of chemopreventive activity of natural products. Planta Med. 74, 1602-1607
    • (2008) Planta Med. , vol.74 , pp. 1602-1607
    • Femia, A.P.1    Caderni, G.2
  • 66
    • 84899458032 scopus 로고    scopus 로고
    • Role of hepatic and intestinal P450 enzymes in the metabolic activation of the colon carcinogen azoxymethane in mice
    • Megaraj, V., Ding, X., Fang, C., Kovalchuk, N., Zhu, Y., and Zhang, Q. Y. (2014) Role of hepatic and intestinal P450 enzymes in the metabolic activation of the colon carcinogen azoxymethane in mice. Chem. Res. Toxicol. 27, 656-662
    • (2014) Chem. Res. Toxicol. , vol.27 , pp. 656-662
    • Megaraj, V.1    Ding, X.2    Fang, C.3    Kovalchuk, N.4    Zhu, Y.5    Zhang, Q.Y.6
  • 67
    • 0019779632 scopus 로고
    • Comparison of the carcinogenicity of methylazoxymethanol-β-D-glucosiduronic acid in conventional and germfree Sprague-Dawley rats
    • Laqueur, G. L., Matsumoto, H., and Yamamoto, R. S. (1981) Comparison of the carcinogenicity of methylazoxymethanol-β-D-glucosiduronic acid in conventional and germfree Sprague-Dawley rats. J. Natl. Cancer Inst. 67, 1053-1055
    • (1981) J. Natl. Cancer Inst. , vol.67 , pp. 1053-1055
    • Laqueur, G.L.1    Matsumoto, H.2    Yamamoto, R.S.3
  • 68
    • 0020058069 scopus 로고
    • Effect of β-glucuronidase inhibitor on azoxymethane-induced colonic carcinogenesis in rats
    • Takada, H., Hirooka, T., Hiramatsu, Y., and Yamamoto, M. (1982) Effect of β-glucuronidase inhibitor on azoxymethane-induced colonic carcinogenesis in rats. Cancer Res. 42, 331-334
    • (1982) Cancer Res. , vol.42 , pp. 331-334
    • Takada, H.1    Hirooka, T.2    Hiramatsu, Y.3    Yamamoto, M.4
  • 69
    • 77951235853 scopus 로고    scopus 로고
    • A comprehensive approach to the profiling of cooked meat carcinogens 2-amino-3,8-dimethylimidazo[4,5- f]quinoxaline, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine, and their metabolites in human urine
    • Gu, D., McNaughton, L., Lemaster, D., Lake, B. G., Gooderham, N. J., Kadlubar, F. F., Turesky, R. J. (2010) A comprehensive approach to the profiling of cooked meat carcinogens 2-amino-3,8-dimethylimidazo[4,5- f]quinoxaline, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine, and their metabolites in human urine. Chem. Res. Toxicol. 23, 788-801
    • (2010) Chem. Res. Toxicol. , vol.23 , pp. 788-801
    • Gu, D.1    McNaughton, L.2    Lemaster, D.3    Lake, B.G.4    Gooderham, N.J.5    Kadlubar, F.F.6    Turesky, R.J.7
  • 70
    • 0036204296 scopus 로고    scopus 로고
    • Glucuronidation: An important mechanism for detoxification of benzo[a]pyrene metabolites in aerodigestive tract tissues
    • Zheng, Z., Fang, J. L., and Lazarus, P. (2002) Glucuronidation: an important mechanism for detoxification of benzo[a]pyrene metabolites in aerodigestive tract tissues. Drug Metab. Dispos. 30, 397-403
    • (2002) Drug Metab. Dispos. , vol.30 , pp. 397-403
    • Zheng, Z.1    Fang, J.L.2    Lazarus, P.3
  • 71
    • 0028927513 scopus 로고
    • Ethyl glucuronide: An unusual ethanol metabolite in humans. Synthesis, analytical data, and determination in serum and urine
    • Schmitt, G., Aderjan, R., Keller, T., and Wu, M. (1995) Ethyl glucuronide: an unusual ethanol metabolite in humans. Synthesis, analytical data, and determination in serum and urine. J. Anal. Toxicol. 19, 91-94
    • (1995) J. Anal. Toxicol. , vol.19 , pp. 91-94
    • Schmitt, G.1    Aderjan, R.2    Keller, T.3    Wu, M.4
  • 72
    • 59249096912 scopus 로고    scopus 로고
    • A review of the use of ethyl glucuronide as a marker for ethanol consumption in forensic and clinical medicine
    • Palmer, R. B. (2009) A review of the use of ethyl glucuronide as a marker for ethanol consumption in forensic and clinical medicine. Semin. Diagn. Pathol. 26, 18-27
    • (2009) Semin. Diagn. Pathol. , vol.26 , pp. 18-27
    • Palmer, R.B.1
  • 74
    • 31544458139 scopus 로고    scopus 로고
    • Determination of ethyl glucuronide in hair samples by liquid chromatography/ electrospray tandem mass spectrometry
    • Morini, L., Politi, L., Groppi, A., Stramesi, C., and Polettini, A. (2006) Determination of ethyl glucuronide in hair samples by liquid chromatography/ electrospray tandem mass spectrometry. J. Mass Spectrom. 41, 34-42
    • (2006) J. Mass Spectrom. , vol.41 , pp. 34-42
    • Morini, L.1    Politi, L.2    Groppi, A.3    Stramesi, C.4    Polettini, A.5
  • 75
    • 77957354096 scopus 로고    scopus 로고
    • Glucuronidation genotypes and nicotine metabolic phenotypes: Importance of functional UGT2B10 and UGT2B17 polymorphisms
    • Chen, G., Giambrone, N. E., Jr., Dluzen, D. F., Muscat, J. E., Berg, A., Gallagher, C. J., and Lazarus, P. (2010) Glucuronidation genotypes and nicotine metabolic phenotypes: importance of functional UGT2B10 and UGT2B17 polymorphisms. Cancer Res. 70, 7543-7552
    • (2010) Cancer Res. , vol.70 , pp. 7543-7552
    • Chen, G.1    Giambrone, N.E.2    Dluzen, D.F.3    Muscat, J.E.4    Berg, A.5    Gallagher, C.J.6    Lazarus, P.7
  • 76
    • 0026586611 scopus 로고
    • Evidence for urinary excretion of glucuronide conjugates of nicotine, cotinine, and trans-3′-hydroxycotinine in smokers
    • Byrd, G. D., Chang, K. M., Greene, J. M., and deBethizy, J. D. (1992) Evidence for urinary excretion of glucuronide conjugates of nicotine, cotinine, and trans-3′-hydroxycotinine in smokers. Drug Metab. Dispos. 20, 192-197
    • (1992) Drug Metab. Dispos. , vol.20 , pp. 192-197
    • Byrd, G.D.1    Chang, K.M.2    Greene, J.M.3    DeBethizy, J.D.4
  • 78
    • 84870858554 scopus 로고    scopus 로고
    • Effects of Gum Arabic ingestion on body mass index and body fat percentage in healthy adult females: Two-arm randomized, placebo controlled, double-blind trial
    • Babiker, R., Merghani, T. H., Elmusharaf, K., Badi, R. M., Lang, F., and Saeed, A. M. (2012) Effects of Gum Arabic ingestion on body mass index and body fat percentage in healthy adult females: two-arm randomized, placebo controlled, double-blind trial. Nutr. J. 11, 111
    • (2012) Nutr. J. , vol.11 , pp. 111
    • Babiker, R.1    Merghani, T.H.2    Elmusharaf, K.3    Badi, R.M.4    Lang, F.5    Saeed, A.M.6
  • 80
    • 0021279858 scopus 로고
    • The effect of milk and Lactobacillus feeding on human intestinal bacterial enzyme activity
    • Goldin, B. R., and Gorbach, S. L. (1984) The effect of milk and Lactobacillus feeding on human intestinal bacterial enzyme activity. Am. J. Clin. Nutr. 39, 756-761
    • (1984) Am. J. Clin. Nutr. , vol.39 , pp. 756-761
    • Goldin, B.R.1    Gorbach, S.L.2
  • 81
    • 22144479029 scopus 로고    scopus 로고
    • Genetic characterization of the β-glucuronidase enzyme from a human intestinal bacterium, Ruminococcus gnavus
    • Beaud, D., Tailliez, P., and Anba-Mondoloni, J. (2005) Genetic characterization of the β-glucuronidase enzyme from a human intestinal bacterium, Ruminococcus gnavus. Microbiology 151, 2323-2330
    • (2005) Microbiology , vol.151 , pp. 2323-2330
    • Beaud, D.1    Tailliez, P.2    Anba-Mondoloni, J.3
  • 82
    • 55949136053 scopus 로고    scopus 로고
    • Distribution of β-glucosidase and β-glucuronidase activity and of β-glucuronidase gene gus in human colonic bacteria
    • Dabek, M., McCrae, S. I., Stevens, V. J., Duncan, S. H., and Louis, P. (2008) Distribution of β-glucosidase and β-glucuronidase activity and of β-glucuronidase gene gus in human colonic bacteria. FEMS Microbiol. Ecol. 66, 487-495
    • (2008) FEMS Microbiol. Ecol. , vol.66 , pp. 487-495
    • Dabek, M.1    McCrae, S.I.2    Stevens, V.J.3    Duncan, S.H.4    Louis, P.5
  • 83
    • 0021950271 scopus 로고
    • β-Glucuronidase activities of intestinal bacteria determined both in vitro and in vivo in gnotobiotic rats
    • Gadelle, D., Raibaud, P., and Sacquet, E. (1985) β-Glucuronidase activities of intestinal bacteria determined both in vitro and in vivo in gnotobiotic rats. Appl. Environ. Microbiol. 49, 682-685
    • (1985) Appl. Environ. Microbiol. , vol.49 , pp. 682-685
    • Gadelle, D.1    Raibaud, P.2    Sacquet, E.3
  • 84
    • 79952754522 scopus 로고    scopus 로고
    • A metagenomic β-glucuronidase uncovers a core adaptive function of the human intestinal microbiome
    • Gloux, K., Berteau, O., El Oumami, H., Béguet, F., Leclerc, M., and Doré, J. (2011) A metagenomic β-glucuronidase uncovers a core adaptive function of the human intestinal microbiome. Proc. Natl. Acad. Sci. U.S.A. 108, 4539-4546
    • (2011) Proc. Natl. Acad. Sci. U.S.A. , vol.108 , pp. 4539-4546
    • Gloux, K.1    Berteau, O.2    El Oumami, H.3    Béguet, F.4    Leclerc, M.5    Doré, J.6
  • 85
    • 0034170336 scopus 로고    scopus 로고
    • Biotransformation of glycyrrhizin by human intestinal bacteria and its relation to biological activities
    • Kim, D. H., Hong, S. W., Kim, B. T., Bae, E. A., Park, H. Y., and Han, M. J. (2000) Biotransformation of glycyrrhizin by human intestinal bacteria and its relation to biological activities. Arch. Pharm. Res. 23, 172-177
    • (2000) Arch. Pharm. Res. , vol.23 , pp. 172-177
    • Kim, D.H.1    Hong, S.W.2    Kim, B.T.3    Bae, E.A.4    Park, H.Y.5    Han, M.J.6
  • 86
    • 0031921036 scopus 로고    scopus 로고
    • Ecological and physiological studies on large intestinal bacteria in relation to production of hydrolytic and reductive enzymes involved in formation of genotoxic metabolites
    • McBain, A. J., and Macfarlane, G. T. (1998) Ecological and physiological studies on large intestinal bacteria in relation to production of hydrolytic and reductive enzymes involved in formation of genotoxic metabolites. J. Med. Microbiol. 47, 407-416
    • (1998) J. Med. Microbiol. , vol.47 , pp. 407-416
    • McBain, A.J.1    Macfarlane, G.T.2
  • 87
    • 0036021108 scopus 로고    scopus 로고
    • Comparison of four microbial enzymes in Clostridia and Bacteroides isolated from human feces
    • Nakamura, J., Kubota, Y., Miyaoka, M., Saitoh, T., Mizuno, F., and Benno, Y. (2002) Comparison of four microbial enzymes in Clostridia and Bacteroides isolated from human feces. Microbiol. Immunol. 46, 487-490
    • (2002) Microbiol. Immunol. , vol.46 , pp. 487-490
    • Nakamura, J.1    Kubota, Y.2    Miyaoka, M.3    Saitoh, T.4    Mizuno, F.5    Benno, Y.6
  • 88
    • 0035287418 scopus 로고    scopus 로고
    • Identification and cloning of gusA, encoding a new β-glucuronidase from Lactobacillus gasseri ADH
    • Russell, W. M., and Klaenhammer, T. R. (2001) Identification and cloning of gusA, encoding a new β-glucuronidase from Lactobacillus gasseri ADH. Appl. Environ. Microbiol. 67, 1253-1261
    • (2001) Appl. Environ. Microbiol. , vol.67 , pp. 1253-1261
    • Russell, W.M.1    Klaenhammer, T.R.2
  • 90
    • 0037145715 scopus 로고    scopus 로고
    • Human colon adenocarcinoma is associated with specific post-translational modifications of versican and decorin
    • Theocharis, A. D. (2002) Human colon adenocarcinoma is associated with specific post-translational modifications of versican and decorin. Biochim. Biophys. Acta 1588, 165-172
    • (2002) Biochim. Biophys. Acta , vol.1588 , pp. 165-172
    • Theocharis, A.D.1
  • 91
    • 38649085337 scopus 로고    scopus 로고
    • Kinetics in serum and urinary excretion of ethyl sulfate and ethyl glucuronide after medium dose ethanol intake
    • Halter, C. C., Dresen, S., Auwaerter, V., Wurst, F. M., and Weinmann, W. (2008) Kinetics in serum and urinary excretion of ethyl sulfate and ethyl glucuronide after medium dose ethanol intake. Int. J. Legal Med. 122, 123-128
    • (2008) Int. J. Legal Med. , vol.122 , pp. 123-128
    • Halter, C.C.1    Dresen, S.2    Auwaerter, V.3    Wurst, F.M.4    Weinmann, W.5


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