Role of hepatic and intestinal P450 enzymes in the metabolic activation of the colon carcinogen azoxymethane in mice

Chemical Research in Toxicology

Volumn 27, Issue 4, 2014, Pages 656-662

  Megaraj, Vandana ^a   Ding, Xinxin ^a   Fang, Cheng ^a   Kovalchuk, Nataliia ^a   Zhu, Yi ^a   Zhang, Qing Yu ^a  

^a STATE UNIVERSITY OF NEW YORK   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

6 O METHYLGUANINE; AZOXYMETHANE; CARCINOGEN; CYTOCHROME P450;

ABERRANT CRYPT FOCUS; ANIMAL TISSUE; ARTICLE; COLON; COLON CANCER; COLON CARCINOGENESIS; CONTROLLED STUDY; DNA ADDUCT; DNA DAMAGE; ENZYME ACTIVITY; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; LIQUID CHROMATOGRAPHY; LIVER; MASS SPECTROMETRY; METABOLIC ACTIVATION; MICROSOME; MOUSE; NONHUMAN; SMALL INTESTINE; TISSUE SPECIFICITY; TOXICOKINETICS; WILD TYPE; ANIMAL; ENZYMOLOGY; GENETICS; INTESTINE; KNOCKOUT MOUSE; METABOLISM;

ACTIVATION, METABOLIC; ANIMALS; AZOXYMETHANE; CARCINOGENS; CYTOCHROME P-450 ENZYME SYSTEM; INTESTINES; LIVER; MICE; MICE, KNOCKOUT;

EID: 84899458032     PISSN: 0893228X     EISSN: 15205010     Source Type: Journal    
DOI: 10.1021/tx4004769     Document Type: Article

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