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Volumn 39, Issue 5, 2017, Pages 551-561

Molecular pathogenesis of viral hemorrhagic fever

Author keywords

Ebola virus; Hemorrhagic fever; Lassa virus; yellow fever virus

Indexed keywords

BLOOD CLOTTING DISORDER; COMPARATIVE STUDY; EBOLA HEMORRHAGIC FEVER; EBOLAVIRUS; HEMORRHAGIC FEVER; HOST PATHOGEN INTERACTION; HUMAN; IMMUNE EVASION; INFLAMMATION; LASSA VIRUS; MOLECULAR PATHOLOGY; NONHUMAN; PRIORITY JOURNAL; REVIEW; SYSTEMS BIOLOGY; VASCULAR DISEASE; VIRAL HEMORRHAGIC FEVER; VIRUS PATHOGENESIS; YELLOW FEVER; YELLOW FEVER VIRUS; ADAPTIVE IMMUNITY; ANIMAL; BLOOD CLOTTING; CAPILLARY PERMEABILITY; DISEASE PREDISPOSITION; GENETICS; IMMUNOLOGY; INNATE IMMUNITY; METABOLISM; VIROLOGY; VIRUS HEMORRHAGIC FEVER;

EID: 85019730404     PISSN: 18632297     EISSN: 18632300     Source Type: Journal    
DOI: 10.1007/s00281-017-0637-x     Document Type: Review
Times cited : (69)

References (112)
  • 1
    • 33644553871 scopus 로고    scopus 로고
    • Linking bats to emerging diseases
    • COI: 1:CAS:528:DC%2BD28XhvFSit7k%3D, PID: 16497913, author reply 1098-1099
    • Fenton MB, Davison M, Kunz TH, McCracken GF, Racey PA, Tuttle MD (2006) Linking bats to emerging diseases. Science 311(5764):1098–1099; author reply 1098-1099. doi:10.1126/science.311.5764.1098c
    • (2006) Science , vol.311 , Issue.5764 , pp. 1098-1099
    • Fenton, M.B.1    Davison, M.2    Kunz, T.H.3    McCracken, G.F.4    Racey, P.A.5    Tuttle, M.D.6
  • 2
    • 84875904431 scopus 로고    scopus 로고
    • Pathogenesis of the viral hemorrhagic fevers
    • COI: 1:CAS:528:DC%2BC3sXltVKqs7g%3D, PID: 23121052
    • Paessler S, Walker DH (2013) Pathogenesis of the viral hemorrhagic fevers. Annu Rev Pathol 8:411–440. doi:10.1146/annurev-pathol-020712-164041
    • (2013) Annu Rev Pathol , vol.8 , pp. 411-440
    • Paessler, S.1    Walker, D.H.2
  • 3
    • 0038150767 scopus 로고    scopus 로고
    • Viral hemorrhagic fever—a vascular disease?
    • COI: 1:CAS:528:DC%2BD3sXlt1Kqt7k%3D, PID: 12783108
    • Schnittler HJ, Feldmann H (2003) Viral hemorrhagic fever—a vascular disease? Thromb Haemost 89(6):967–972. doi:10.1267/THRO03060967
    • (2003) Thromb Haemost , vol.89 , Issue.6 , pp. 967-972
    • Schnittler, H.J.1    Feldmann, H.2
  • 5
    • 0034881704 scopus 로고    scopus 로고
    • COI: 1:CAS:528:DC%2BD3MXlvVOltrs%3D, PID: 11479607
    • Birmingham K, Kenyon G (2001) Nat Med 7(8):878–878. doi:10.1038/90892
    • (2001) Nat Med , vol.7 , Issue.8 , pp. 878
    • Birmingham, K.1    Kenyon, G.2
  • 6
    • 0023155704 scopus 로고
    • A prospective study of the epidemiology and ecology of Lassa fever
    • COI: 1:STN:280:DyaL2s7htVyltQ%3D%3D, PID: 3805771
    • McCormick JB, Webb PA, Krebs JW, Johnson KM, Smith ES (1987) A prospective study of the epidemiology and ecology of Lassa fever. J Infect Dis 155(3):437–444
    • (1987) J Infect Dis , vol.155 , Issue.3 , pp. 437-444
    • McCormick, J.B.1    Webb, P.A.2    Krebs, J.W.3    Johnson, K.M.4    Smith, E.S.5
  • 7
    • 84979608998 scopus 로고    scopus 로고
    • Yellow fever remains a potential threat to public health
    • PID: 27400066
    • Vasconcelos PF, Monath TP (2016) Yellow fever remains a potential threat to public health. Vector Borne Zoonotic Dis 16(8):566–567. doi:10.1089/vbz.2016.2031
    • (2016) Vector Borne Zoonotic Dis , vol.16 , Issue.8 , pp. 566-567
    • Vasconcelos, P.F.1    Monath, T.P.2
  • 12
    • 84939231436 scopus 로고    scopus 로고
    • Assessing the evidence supporting fruit bats as the primary reservoirs for Ebola viruses
    • PID: 26268210
    • Leendertz SA, Gogarten JF, Dux A, Calvignac-Spencer S, Leendertz FH (2015) Assessing the evidence supporting fruit bats as the primary reservoirs for Ebola viruses. EcoHealth 13(1):18–25. doi:10.1007/s10393-015-1053-0
    • (2015) EcoHealth , vol.13 , Issue.1 , pp. 18-25
    • Leendertz, S.A.1    Gogarten, J.F.2    Dux, A.3    Calvignac-Spencer, S.4    Leendertz, F.H.5
  • 13
    • 84936940562 scopus 로고    scopus 로고
    • Experimental inoculation of Egyptian rousette bats (Rousettus aegyptiacus) with viruses of the Ebolavirus and Marburgvirus genera
    • COI: 1:CAS:528:DC%2BC2MXhslOqt7vO, PID: 26120867
    • Jones ME, Schuh AJ, Amman BR, Sealy TK, Zaki SR, Nichol ST, Towner JS (2015) Experimental inoculation of Egyptian rousette bats (Rousettus aegyptiacus) with viruses of the Ebolavirus and Marburgvirus genera. Viruses 7(7):3420–3442. doi:10.3390/v7072779
    • (2015) Viruses , vol.7 , Issue.7 , pp. 3420-3442
    • Jones, M.E.1    Schuh, A.J.2    Amman, B.R.3    Sealy, T.K.4    Zaki, S.R.5    Nichol, S.T.6    Towner, J.S.7
  • 14
    • 80054741233 scopus 로고    scopus 로고
    • Basic clinical and laboratory features of filoviral hemorrhagic fever
    • PID: 21987756
    • Kortepeter MG, Bausch DG, Bray M (2011) Basic clinical and laboratory features of filoviral hemorrhagic fever. J Infect Dis 204(Suppl 3):S810–S816. doi:10.1093/infdis/jir299
    • (2011) J Infect Dis , vol.204 , pp. S810-S816
    • Kortepeter, M.G.1    Bausch, D.G.2    Bray, M.3
  • 15
    • 0031740790 scopus 로고    scopus 로고
    • Pathologic features of filovirus infections in humans
    • COI: 1:STN:280:DyaK1M7gvFamuw%3D%3D, PID: 9893381
    • Zaki SR, Goldsmith CS (1999) Pathologic features of filovirus infections in humans. Curr Top Microbiol Immunol 235:97–116
    • (1999) Curr Top Microbiol Immunol , vol.235 , pp. 97-116
    • Zaki, S.R.1    Goldsmith, C.S.2
  • 16
    • 0034006617 scopus 로고    scopus 로고
    • Apoptosis induced in vitro and in vivo during infection by Ebola and Marburg viruses
    • COI: 1:STN:280:DC%2BD3c7mtlKhsA%3D%3D, PID: 10701687
    • Geisbert TW, Hensley LE, Gibb TR, Steele KE, Jaax NK, Jahrling PB (2000) Apoptosis induced in vitro and in vivo during infection by Ebola and Marburg viruses. Lab Investig 80(2):171–186
    • (2000) Lab Investig , vol.80 , Issue.2 , pp. 171-186
    • Geisbert, T.W.1    Hensley, L.E.2    Gibb, T.R.3    Steele, K.E.4    Jaax, N.K.5    Jahrling, P.B.6
  • 17
    • 84917671407 scopus 로고    scopus 로고
    • Tissue and cellular tropism, pathology and pathogenesis of Ebola and Marburg viruses
    • COI: 1:CAS:528:DC%2BC2cXitV2gtrvK, PID: 25297522
    • Martines RB, Ng DL, Greer PW, Rollin PE, Zaki SR (2015) Tissue and cellular tropism, pathology and pathogenesis of Ebola and Marburg viruses. J Pathol 235(2):153–174. doi:10.1002/path.4456
    • (2015) J Pathol , vol.235 , Issue.2 , pp. 153-174
    • Martines, R.B.1    Ng, D.L.2    Greer, P.W.3    Rollin, P.E.4    Zaki, S.R.5
  • 18
    • 0032907635 scopus 로고    scopus 로고
    • Defective humoral responses and extensive intravascular apoptosis are associated with fatal outcome in Ebola virus-infected patients
    • COI: 1:CAS:528:DyaK1MXisFOlt7o%3D, PID: 10202932
    • Baize S, Leroy EM, Georges-Courbot MC, Capron M, Lansoud-Soukate J, Debre P, Fisher-Hoch SP, McCormick JB, Georges AJ (1999) Defective humoral responses and extensive intravascular apoptosis are associated with fatal outcome in Ebola virus-infected patients. Nat Med 5(4):423–426
    • (1999) Nat Med , vol.5 , Issue.4 , pp. 423-426
    • Baize, S.1    Leroy, E.M.2    Georges-Courbot, M.C.3    Capron, M.4    Lansoud-Soukate, J.5    Debre, P.6    Fisher-Hoch, S.P.7    McCormick, J.B.8    Georges, A.J.9
  • 19
    • 10744224131 scopus 로고    scopus 로고
    • Pathogenesis of Ebola hemorrhagic fever in cynomolgus macaques: evidence that dendritic cells are early and sustained targets of infection
    • COI: 1:CAS:528:DC%2BD2cXkslKh, PID: 14633608
    • Geisbert TW, Hensley LE, Larsen T, Young HA, Reed DS, Geisbert JB, Scott DP, Kagan E, Jahrling PB, Davis KJ (2003) Pathogenesis of Ebola hemorrhagic fever in cynomolgus macaques: evidence that dendritic cells are early and sustained targets of infection. Am J Pathol 163(6):2347–2370
    • (2003) Am J Pathol , vol.163 , Issue.6 , pp. 2347-2370
    • Geisbert, T.W.1    Hensley, L.E.2    Larsen, T.3    Young, H.A.4    Reed, D.S.5    Geisbert, J.B.6    Scott, D.P.7    Kagan, E.8    Jahrling, P.B.9    Davis, K.J.10
  • 20
    • 47049129961 scopus 로고    scopus 로고
    • Cell adhesion promotes Ebola virus envelope glycoprotein-mediated binding and infection
    • COI: 1:CAS:528:DC%2BD1cXosFWmsLg%3D, PID: 18448524
    • Dube D, Schornberg KL, Stantchev TS, Bonaparte MI, Delos SE, Bouton AH, Broder CC, White JM (2008) Cell adhesion promotes Ebola virus envelope glycoprotein-mediated binding and infection. J Virol 82(14):7238–7242. doi:10.1128/JVI.00425-08
    • (2008) J Virol , vol.82 , Issue.14 , pp. 7238-7242
    • Dube, D.1    Schornberg, K.L.2    Stantchev, T.S.3    Bonaparte, M.I.4    Delos, S.E.5    Bouton, A.H.6    Broder, C.C.7    White, J.M.8
  • 21
    • 4544293451 scopus 로고    scopus 로고
    • Depletion of peripheral blood T lymphocytes and NK cells during the course of Ebola hemorrhagic fever in cynomolgus macaques
    • COI: 1:CAS:528:DC%2BD2cXntlequ7g%3D, PID: 15357905
    • Reed DS, Hensley LE, Geisbert JB, Jahrling PB, Geisbert TW (2004) Depletion of peripheral blood T lymphocytes and NK cells during the course of Ebola hemorrhagic fever in cynomolgus macaques. Viral Immunol 17(3):390–400
    • (2004) Viral Immunol , vol.17 , Issue.3 , pp. 390-400
    • Reed, D.S.1    Hensley, L.E.2    Geisbert, J.B.3    Jahrling, P.B.4    Geisbert, T.W.5
  • 22
    • 0036498098 scopus 로고    scopus 로고
    • Proinflammatory response during Ebola virus infection of primate models: possible involvement of the tumor necrosis factor receptor superfamily
    • COI: 1:CAS:528:DC%2BD38XmsFGnsQ%3D%3D, PID: 11803049
    • Hensley LE, Young HA, Jahrling PB, Geisbert TW (2002) Proinflammatory response during Ebola virus infection of primate models: possible involvement of the tumor necrosis factor receptor superfamily. Immunol Lett 80(3):169–179
    • (2002) Immunol Lett , vol.80 , Issue.3 , pp. 169-179
    • Hensley, L.E.1    Young, H.A.2    Jahrling, P.B.3    Geisbert, T.W.4
  • 23
    • 78449261317 scopus 로고    scopus 로고
    • Human fatal zaire ebola virus infection is associated with an aberrant innate immunity and with massive lymphocyte apoptosis
    • PID: 20957152
    • Wauquier N, Becquart P, Padilla C, Baize S, Leroy EM (2010) Human fatal zaire ebola virus infection is associated with an aberrant innate immunity and with massive lymphocyte apoptosis. PLoS Negl Trop Dis 4(10):e837. doi:10.1371/journal.pntd.0000837
    • (2010) PLoS Negl Trop Dis , vol.4 , Issue.10
    • Wauquier, N.1    Becquart, P.2    Padilla, C.3    Baize, S.4    Leroy, E.M.5
  • 24
    • 0347122085 scopus 로고    scopus 로고
    • Ebola and Marburg viruses replicate in monocyte-derived dendritic cells without inducing the production of cytokines and full maturation
    • COI: 1:CAS:528:DC%2BD2cXktlOisQ%3D%3D, PID: 14639532
    • Bosio CM, Aman MJ, Grogan C, Hogan R, Ruthel G, Negley D, Mohamadzadeh M, Bavari S, Schmaljohn A (2003) Ebola and Marburg viruses replicate in monocyte-derived dendritic cells without inducing the production of cytokines and full maturation. J Infect Dis 188(11):1630–1638
    • (2003) J Infect Dis , vol.188 , Issue.11 , pp. 1630-1638
    • Bosio, C.M.1    Aman, M.J.2    Grogan, C.3    Hogan, R.4    Ruthel, G.5    Negley, D.6    Mohamadzadeh, M.7    Bavari, S.8    Schmaljohn, A.9
  • 25
    • 0037443448 scopus 로고    scopus 로고
    • Cutting edge: impairment of dendritic cells and adaptive immunity by Ebola and Lassa viruses
    • COI: 1:CAS:528:DC%2BD3sXhslOkuro%3D, PID: 12626527
    • Mahanty S, Hutchinson K, Agarwal S, McRae M, Rollin PE, Pulendran B (2003) Cutting edge: impairment of dendritic cells and adaptive immunity by Ebola and Lassa viruses. J Immunol 170(6):2797–2801
    • (2003) J Immunol , vol.170 , Issue.6 , pp. 2797-2801
    • Mahanty, S.1    Hutchinson, K.2    Agarwal, S.3    McRae, M.4    Rollin, P.E.5    Pulendran, B.6
  • 26
    • 4544228226 scopus 로고    scopus 로고
    • Analysis of human peripheral blood samples from fatal and nonfatal cases of Ebola (Sudan) hemorrhagic fever: cellular responses, virus load, and nitric oxide levels
    • COI: 1:CAS:528:DC%2BD2cXotVemsLw%3D, PID: 15367603
    • Sanchez A, Lukwiya M, Bausch D, Mahanty S, Sanchez AJ, Wagoner KD, Rollin PE (2004) Analysis of human peripheral blood samples from fatal and nonfatal cases of Ebola (Sudan) hemorrhagic fever: cellular responses, virus load, and nitric oxide levels. J Virol 78(19):10370–10377
    • (2004) J Virol , vol.78 , Issue.19 , pp. 10370-10377
    • Sanchez, A.1    Lukwiya, M.2    Bausch, D.3    Mahanty, S.4    Sanchez, A.J.5    Wagoner, K.D.6    Rollin, P.E.7
  • 28
    • 33845626928 scopus 로고    scopus 로고
    • Implication of a retrovirus-like glycoprotein peptide in the immunopathogenesis of Ebola and Marburg viruses
    • COI: 1:CAS:528:DC%2BD28Xht1OmsLfP, PID: 17023517
    • Yaddanapudi K, Palacios G, Towner JS, Chen I, Sariol CA, Nichol ST, Lipkin WI (2006) Implication of a retrovirus-like glycoprotein peptide in the immunopathogenesis of Ebola and Marburg viruses. FASEB J 20(14):2519–2530
    • (2006) FASEB J , vol.20 , Issue.14 , pp. 2519-2530
    • Yaddanapudi, K.1    Palacios, G.2    Towner, J.S.3    Chen, I.4    Sariol, C.A.5    Nichol, S.T.6    Lipkin, W.I.7
  • 29
    • 80054770588 scopus 로고    scopus 로고
    • Host response dynamics following lethal infection of rhesus macaques with Zaire ebolavirus
    • COI: 1:CAS:528:DC%2BC3MXhtlaqurzL, PID: 21987781
    • Ebihara H, Rockx B, Marzi A, Feldmann F, Haddock E, Brining D, LaCasse RA, Gardner D, Feldmann H (2011) Host response dynamics following lethal infection of rhesus macaques with Zaire ebolavirus. J Infect Dis 204(Suppl 3):S991–S999. doi:10.1093/infdis/jir336
    • (2011) J Infect Dis , vol.204 , pp. S991-S999
    • Ebihara, H.1    Rockx, B.2    Marzi, A.3    Feldmann, F.4    Haddock, E.5    Brining, D.6    LaCasse, R.A.7    Gardner, D.8    Feldmann, H.9
  • 30
    • 38449099004 scopus 로고    scopus 로고
    • Cytokine and chemokine expression in humans infected with Sudan Ebola virus
    • COI: 1:CAS:528:DC%2BD2sXhsVamsr%2FF, PID: 17940971
    • Hutchinson KL, Rollin PE (2007) Cytokine and chemokine expression in humans infected with Sudan Ebola virus. J Infect Dis 196(Suppl 2):S357–S363
    • (2007) J Infect Dis , vol.196 , pp. S357-S363
    • Hutchinson, K.L.1    Rollin, P.E.2
  • 32
    • 0032997843 scopus 로고    scopus 로고
    • Markedly elevated levels of interferon (IFN)-gamma, IFN-alpha, interleukin (IL)-2, IL-10, and tumor necrosis factor-alpha associated with fatal Ebola virus infection
    • COI: 1:CAS:528:DyaK1MXhtVeltrk%3D, PID: 9988183
    • Villinger F, Rollin PE, Brar SS, Chikkala NF, Winter J, Sundstrom JB, Zaki SR, Swanepoel R, Ansari AA, Peters CJ (1999) Markedly elevated levels of interferon (IFN)-gamma, IFN-alpha, interleukin (IL)-2, IL-10, and tumor necrosis factor-alpha associated with fatal Ebola virus infection. J Infect Dis 179(Suppl 1):S188–S191
    • (1999) J Infect Dis , vol.179 , pp. S188-S191
    • Villinger, F.1    Rollin, P.E.2    Brar, S.S.3    Chikkala, N.F.4    Winter, J.5    Sundstrom, J.B.6    Zaki, S.R.7    Swanepoel, R.8    Ansari, A.A.9    Peters, C.J.10
  • 33
    • 0035947156 scopus 로고    scopus 로고
    • Monocyte-derived human macrophages and peripheral blood mononuclear cells infected with ebola virus secrete MIP-1alpha and TNF-alpha and inhibit poly-IC-induced IFN-alpha in vitro
    • COI: 1:CAS:528:DC%2BD3MXjsVGiu7k%3D, PID: 11352664
    • Gupta M, Mahanty S, Ahmed R, Rollin PE (2001) Monocyte-derived human macrophages and peripheral blood mononuclear cells infected with ebola virus secrete MIP-1alpha and TNF-alpha and inhibit poly-IC-induced IFN-alpha in vitro. Virology 284(1):20–25
    • (2001) Virology , vol.284 , Issue.1 , pp. 20-25
    • Gupta, M.1    Mahanty, S.2    Ahmed, R.3    Rollin, P.E.4
  • 34
    • 0034755148 scopus 로고    scopus 로고
    • Infection and activation of monocytes by Marburg and Ebola viruses
    • COI: 1:CAS:528:DC%2BD3MXnvVeltLg%3D, PID: 11602743
    • Stroher U, West E, Bugany H, Klenk HD, Schnittler HJ, Feldmann H (2001) Infection and activation of monocytes by Marburg and Ebola viruses. J Virol 75(22):11025–11033
    • (2001) J Virol , vol.75 , Issue.22 , pp. 11025-11033
    • Stroher, U.1    West, E.2    Bugany, H.3    Klenk, H.D.4    Schnittler, H.J.5    Feldmann, H.6
  • 35
    • 38449083350 scopus 로고    scopus 로고
    • Blood chemistry measurements and D-dimer levels associated with fatal and nonfatal outcomes in humans infected with Sudan Ebola virus
    • COI: 1:CAS:528:DC%2BD2sXhsVamsrzM, PID: 17940972
    • Rollin PE, Bausch DG, Sanchez A (2007) Blood chemistry measurements and D-dimer levels associated with fatal and nonfatal outcomes in humans infected with Sudan Ebola virus. J Infect Dis 196(Suppl 2):S364–S371. doi:10.1086/520613
    • (2007) J Infect Dis , vol.196 , pp. S364-S371
    • Rollin, P.E.1    Bausch, D.G.2    Sanchez, A.3
  • 36
    • 0003463878 scopus 로고
    • Clinical aspects of Ebola virus disease at the Ngaliema hospital, Kinshasa, Zaire, 1976
    • Elsevier/North Holland Biomedical Press, New York
    • Isaacson MSP, Courteille G (1976) Clinical aspects of Ebola virus disease at the Ngaliema hospital, Kinshasa, Zaire, 1976. In: Ebola Virus Haemorrhagic Fever. Elsevier/North Holland Biomedical Press, New York
    • (1976) In: Ebola Virus Haemorrhagic Fever
    • Isaacson, M.S.P.1    Courteille, G.2
  • 37
    • 0018188505 scopus 로고
    • Ebola haemorrhagic fever in Sudan, 1976. Report of a WHO/International Study Team
    • Organization WH (1978) Ebola haemorrhagic fever in Sudan, 1976. Report of a WHO/International Study Team. Bull World Health Organ 58:247–270
    • (1978) Bull World Health Organ , vol.58 , pp. 247-270
    • Organization, W.H.1
  • 38
    • 0345445900 scopus 로고    scopus 로고
    • Pathogenesis of Ebola hemorrhagic fever in primate models: evidence that hemorrhage is not a direct effect of virus-induced cytolysis of endothelial cells
    • COI: 1:CAS:528:DC%2BD2cXkslKg, PID: 14633609
    • Geisbert TW, Young HA, Jahrling PB, Davis KJ, Larsen T, Kagan E, Hensley LE (2003) Pathogenesis of Ebola hemorrhagic fever in primate models: evidence that hemorrhage is not a direct effect of virus-induced cytolysis of endothelial cells. Am J Pathol 163(6):2371–2382. doi:10.1016/S0002-9440(10)63592-4
    • (2003) Am J Pathol , vol.163 , Issue.6 , pp. 2371-2382
    • Geisbert, T.W.1    Young, H.A.2    Jahrling, P.B.3    Davis, K.J.4    Larsen, T.5    Kagan, E.6    Hensley, L.E.7
  • 40
    • 0035659667 scopus 로고    scopus 로고
    • Pathogenesis of experimental Ebola Zaire virus infection in BALB/c mice
    • COI: 1:STN:280:DC%2BD38%2Fnt1Grsg%3D%3D, PID: 11798240
    • Gibb TR, Bray M, Geisbert TW, Steele KE, Kell WM, Davis KJ, Jaax NK (2001) Pathogenesis of experimental Ebola Zaire virus infection in BALB/c mice. J Comp Pathol 125(4):233–242
    • (2001) J Comp Pathol , vol.125 , Issue.4 , pp. 233-242
    • Gibb, T.R.1    Bray, M.2    Geisbert, T.W.3    Steele, K.E.4    Kell, W.M.5    Davis, K.J.6    Jaax, N.K.7
  • 41
    • 80054745108 scopus 로고    scopus 로고
    • Pathogenesis of Marburg hemorrhagic fever in cynomolgus macaques
    • COI: 1:CAS:528:DC%2BC3MXhtlaqurzP, PID: 21987738
    • Hensley LE, Alves DA, Geisbert JB, Fritz EA, Reed C, Larsen T, Geisbert TW (2011) Pathogenesis of Marburg hemorrhagic fever in cynomolgus macaques. J Infect Dis 204(Suppl 3):S1021–S1031. doi:10.1093/infdis/jir339
    • (2011) J Infect Dis , vol.204 , pp. S1021-S1031
    • Hensley, L.E.1    Alves, D.A.2    Geisbert, J.B.3    Fritz, E.A.4    Reed, C.5    Larsen, T.6    Geisbert, T.W.7
  • 43
    • 84880347654 scopus 로고    scopus 로고
    • The lack of maturation of Ebola virus-infected dendritic cells results from the cooperative effect of at least two viral domains
    • COI: 1:CAS:528:DC%2BC3sXpvFCqt74%3D, PID: 23616668
    • Lubaki NM, Ilinykh P, Pietzsch C, Tigabu B, Freiberg AN, Koup RA, Bukreyev A (2013) The lack of maturation of Ebola virus-infected dendritic cells results from the cooperative effect of at least two viral domains. J Virol 87(13):7471–7485. doi:10.1128/JVI.03316-12
    • (2013) J Virol , vol.87 , Issue.13 , pp. 7471-7485
    • Lubaki, N.M.1    Ilinykh, P.2    Pietzsch, C.3    Tigabu, B.4    Freiberg, A.N.5    Koup, R.A.6    Bukreyev, A.7
  • 46
    • 84896987305 scopus 로고    scopus 로고
    • Interferon-stimulated genes: a complex web of host defenses
    • COI: 1:CAS:528:DC%2BC2cXovVemt7c%3D, PID: 24555472
    • Schneider WM, Chevillotte MD, Rice CM (2014) Interferon-stimulated genes: a complex web of host defenses. Annu Rev Immunol 32:513–545. doi:10.1146/annurev-immunol-032713-120231
    • (2014) Annu Rev Immunol , vol.32 , pp. 513-545
    • Schneider, W.M.1    Chevillotte, M.D.2    Rice, C.M.3
  • 47
    • 84898728217 scopus 로고    scopus 로고
    • Interferon-stimulated genes: roles in viral pathogenesis
    • COI: 1:CAS:528:DC%2BC2cXhtVarsLnI, PID: 24713352
    • Schoggins JW (2014) Interferon-stimulated genes: roles in viral pathogenesis. Curr Opin Virol 6:40–46. doi:10.1016/j.coviro.2014.03.006
    • (2014) Curr Opin Virol , vol.6 , pp. 40-46
    • Schoggins, J.W.1
  • 48
    • 33646748294 scopus 로고    scopus 로고
    • Ebola virus VP35 protein binds double-stranded RNA and inhibits alpha/beta interferon production induced by RIG-I signaling
    • COI: 1:CAS:528:DC%2BD28XlsVGnt78%3D, PID: 16698997
    • Cardenas WB, Loo YM, Gale M Jr, Hartman AL, Kimberlin CR, Martinez-Sobrido L, Saphire EO, Basler CF (2006) Ebola virus VP35 protein binds double-stranded RNA and inhibits alpha/beta interferon production induced by RIG-I signaling. J Virol 80(11):5168–5178
    • (2006) J Virol , vol.80 , Issue.11 , pp. 5168-5178
    • Cardenas, W.B.1    Loo, Y.M.2    Gale, M.3    Hartman, A.L.4    Kimberlin, C.R.5    Martinez-Sobrido, L.6    Saphire, E.O.7    Basler, C.F.8
  • 49
    • 0031657064 scopus 로고    scopus 로고
    • Three of the four nucleocapsid proteins of Marburg virus, NP, VP35, and L, are sufficient to mediate replication and transcription of Marburg virus-specific monocistronic minigenomes
    • COI: 1:CAS:528:DyaK1cXmslaitbg%3D, PID: 9765419
    • Muhlberger E, Lotfering B, Klenk HD, Becker S (1998) Three of the four nucleocapsid proteins of Marburg virus, NP, VP35, and L, are sufficient to mediate replication and transcription of Marburg virus-specific monocistronic minigenomes. J Virol 72(11):8756–8764
    • (1998) J Virol , vol.72 , Issue.11 , pp. 8756-8764
    • Muhlberger, E.1    Lotfering, B.2    Klenk, H.D.3    Becker, S.4
  • 50
    • 0142159487 scopus 로고    scopus 로고
    • Comparison of the transcription and replication strategies of marburg virus and Ebola virus by using artificial replication systems
    • COI: 1:CAS:528:DyaK1MXhvVWnt7Y%3D, PID: 9971816
    • Muhlberger E, Weik M, Volchkov VE, Klenk HD, Becker S (1999) Comparison of the transcription and replication strategies of marburg virus and Ebola virus by using artificial replication systems. J Virol 73(3):2333–2342
    • (1999) J Virol , vol.73 , Issue.3 , pp. 2333-2342
    • Muhlberger, E.1    Weik, M.2    Volchkov, V.E.3    Klenk, H.D.4    Becker, S.5
  • 53
    • 40149109042 scopus 로고    scopus 로고
    • Inhibition of IRF-3 activation by VP35 is critical for the high level of virulence of ebola virus
    • COI: 1:CAS:528:DC%2BD1cXjtVart7s%3D, PID: 18199658
    • Hartman AL, Bird BH, Towner JS, Antoniadou ZA, Zaki SR, Nichol ST (2008) Inhibition of IRF-3 activation by VP35 is critical for the high level of virulence of ebola virus. J Virol 82(6):2699–2704
    • (2008) J Virol , vol.82 , Issue.6 , pp. 2699-2704
    • Hartman, A.L.1    Bird, B.H.2    Towner, J.S.3    Antoniadou, Z.A.4    Zaki, S.R.5    Nichol, S.T.6
  • 54
    • 84862604699 scopus 로고    scopus 로고
    • Structural insights into RNA recognition and activation of RIG-I-like receptors
    • COI: 1:CAS:528:DC%2BC38XmsVanu7s%3D, PID: 22560447
    • Leung DW, Amarasinghe GK (2012) Structural insights into RNA recognition and activation of RIG-I-like receptors. Curr Opin Struct Biol 22(3):297–303. doi:10.1016/j.sbi.2012.03.011
    • (2012) Curr Opin Struct Biol , vol.22 , Issue.3 , pp. 297-303
    • Leung, D.W.1    Amarasinghe, G.K.2
  • 55
    • 63149113399 scopus 로고    scopus 로고
    • Ebola virus protein VP35 impairs the function of interferon regulatory factor-activating kinases IKKepsilon and TBK-1
    • COI: 1:CAS:528:DC%2BD1MXjs1Wrtr0%3D, PID: 19153231
    • Prins KC, Cardenas WB, Basler CF (2009) Ebola virus protein VP35 impairs the function of interferon regulatory factor-activating kinases IKKepsilon and TBK-1. J Virol 83(7):3069–3077. doi:10.1128/JVI.01875-08
    • (2009) J Virol , vol.83 , Issue.7 , pp. 3069-3077
    • Prins, K.C.1    Cardenas, W.B.2    Basler, C.F.3
  • 56
    • 67650866693 scopus 로고    scopus 로고
    • Ebola Zaire virus blocks type I interferon production by exploiting the host SUMO modification machinery
    • PID: 19557165
    • Chang TH, Kubota T, Matsuoka M, Jones S, Bradfute SB, Bray M, Ozato K (2009) Ebola Zaire virus blocks type I interferon production by exploiting the host SUMO modification machinery. PLoS Pathog 5(6):e1000493. doi:10.1371/journal.ppat.1000493
    • (2009) PLoS Pathog , vol.5 , Issue.6
    • Chang, T.H.1    Kubota, T.2    Matsuoka, M.3    Jones, S.4    Bradfute, S.B.5    Bray, M.6    Ozato, K.7
  • 58
    • 43949091157 scopus 로고    scopus 로고
    • Whole genome expression profiling reveals that inhibition of host innate immune response pathways by Ebola virus can be reversed by a single amino acid change in the VP35 protein
    • COI: 1:CAS:528:DC%2BD1cXmt1SlsrY%3D, PID: 18353943
    • Hartman AL, Ling L, Nichol ST, Hibberd ML (2008) Whole genome expression profiling reveals that inhibition of host innate immune response pathways by Ebola virus can be reversed by a single amino acid change in the VP35 protein. J Virol 82:5348–5358
    • (2008) J Virol , vol.82 , pp. 5348-5358
    • Hartman, A.L.1    Ling, L.2    Nichol, S.T.3    Hibberd, M.L.4
  • 60
    • 0035838984 scopus 로고    scopus 로고
    • Dendritic cells: specialized and regulated antigen processing machines
    • COI: 1:CAS:528:DC%2BD3MXmtFKnsL4%3D, PID: 11509172
    • Mellman I, Steinman RM (2001) Dendritic cells: specialized and regulated antigen processing machines. Cell 106(3):255–258
    • (2001) Cell , vol.106 , Issue.3 , pp. 255-258
    • Mellman, I.1    Steinman, R.M.2
  • 61
    • 84908006847 scopus 로고    scopus 로고
    • Molecular basis for ebolavirus VP35 suppression of human dendritic cell maturation
    • PID: 25142601
    • Yen B, Mulder LC, Martinez O, Basler CF (2014) Molecular basis for ebolavirus VP35 suppression of human dendritic cell maturation. J Virol 88(21):12500–12510. doi:10.1128/JVI.02163-14
    • (2014) J Virol , vol.88 , Issue.21 , pp. 12500-12510
    • Yen, B.1    Mulder, L.C.2    Martinez, O.3    Basler, C.F.4
  • 62
    • 84975307420 scopus 로고    scopus 로고
    • Effects of filovirus interferon antagonists on responses of human monocyte-derived dendritic cells to RNA virus infection
    • COI: 1:CAS:528:DC%2BC28XhsVOgsrvF, PID: 26962215
    • Yen BC, Basler CF (2016) Effects of filovirus interferon antagonists on responses of human monocyte-derived dendritic cells to RNA virus infection. J Virol 90(10):5108–5118. doi:10.1128/JVI.00191-16
    • (2016) J Virol , vol.90 , Issue.10 , pp. 5108-5118
    • Yen, B.C.1    Basler, C.F.2
  • 63
    • 76249118239 scopus 로고    scopus 로고
    • The VP35 protein of Ebola virus impairs dendritic cell maturation induced by virus and lipopolysaccharide
    • COI: 1:CAS:528:DC%2BC3cXis1equ7k%3D, PID: 19828757
    • Jin H, Yan Z, Prabhakar BS, Feng Z, Ma Y, Verpooten D, Ganesh B, He B (2010) The VP35 protein of Ebola virus impairs dendritic cell maturation induced by virus and lipopolysaccharide. J Gen Virol 91(Pt 2):352–361. doi:10.1099/vir.0.017343-0
    • (2010) J Gen Virol , vol.91 , pp. 352-361
    • Jin, H.1    Yan, Z.2    Prabhakar, B.S.3    Feng, Z.4    Ma, Y.5    Verpooten, D.6    Ganesh, B.7    He, B.8
  • 64
    • 84919360204 scopus 로고    scopus 로고
    • Recombinant Marburg viruses containing mutations in the IID region of VP35 prevent inhibition of host immune responses
    • COI: 1:CAS:528:DC%2BC2cXitFygs7%2FJ, PID: 25531184
    • Albarino CG, Wiggleton Guerrero L, Spengler JR, Uebelhoer LS, Chakrabarti AK, Nichol ST, Towner JS (2015) Recombinant Marburg viruses containing mutations in the IID region of VP35 prevent inhibition of host immune responses. Virology 476:85–91. doi:10.1016/j.virol.2014.12.002
    • (2015) Virology , vol.476 , pp. 85-91
    • Albarino, C.G.1    Wiggleton Guerrero, L.2    Spengler, J.R.3    Uebelhoer, L.S.4    Chakrabarti, A.K.5    Nichol, S.T.6    Towner, J.S.7
  • 67
    • 0042977521 scopus 로고    scopus 로고
    • The ins and outs of STAT1 nuclear transport
    • PID: 12915721
    • McBride KM, Reich NC (2003) The ins and outs of STAT1 nuclear transport. Sci STKE 2003(195):RE13. doi:10.1126/stke.2003.195.re13
    • (2003) Sci STKE , vol.2003 , Issue.195 , pp. RE13
    • McBride, K.M.1    Reich, N.C.2
  • 70
    • 37149040796 scopus 로고    scopus 로고
    • Ebola virus VP24 proteins inhibit the interaction of NPI-1 subfamily karyopherin alpha proteins with activated STAT1
    • COI: 1:CAS:528:DC%2BD2sXhsValsbvO, PID: 17928350
    • Reid SP, Valmas C, Martinez O, Sanchez FM, Basler CF (2007) Ebola virus VP24 proteins inhibit the interaction of NPI-1 subfamily karyopherin alpha proteins with activated STAT1. J Virol 81(24):13469–13477
    • (2007) J Virol , vol.81 , Issue.24 , pp. 13469-13477
    • Reid, S.P.1    Valmas, C.2    Martinez, O.3    Sanchez, F.M.4    Basler, C.F.5
  • 73
    • 79955407974 scopus 로고    scopus 로고
    • Marburg virus VP40 antagonizes interferon signaling in a species-specific manner
    • COI: 1:CAS:528:DC%2BC3MXhtVSmsLnJ, PID: 21325424
    • Valmas C, Basler CF (2011) Marburg virus VP40 antagonizes interferon signaling in a species-specific manner. J Virol 85(9):4309–4317. doi:10.1128/JVI.02575-10
    • (2011) J Virol , vol.85 , Issue.9 , pp. 4309-4317
    • Valmas, C.1    Basler, C.F.2
  • 74
    • 69249205651 scopus 로고    scopus 로고
    • Ebola virus VP35 antagonizes PKR activity through its C-terminal interferon inhibitory domain
    • PID: 19515768
    • Schumann M, Gantke T, Muhlberger E (2009) Ebola virus VP35 antagonizes PKR activity through its C-terminal interferon inhibitory domain. J Virol 83(17):8993–8997. doi:10.1128/JVI.00523-09
    • (2009) J Virol , vol.83 , Issue.17 , pp. 8993-8997
    • Schumann, M.1    Gantke, T.2    Muhlberger, E.3
  • 75
    • 62449106199 scopus 로고    scopus 로고
    • Tetherin-mediated restriction of filovirus budding is antagonized by the Ebola glycoprotein
    • COI: 1:CAS:528:DC%2BD1MXislSktro%3D, PID: 19179289
    • Kaletsky RL, Francica JR, Agrawal-Gamse C, Bates P (2009) Tetherin-mediated restriction of filovirus budding is antagonized by the Ebola glycoprotein. Proc Natl Acad Sci U S A 106(8):2886–2891. doi:10.1073/pnas.0811014106
    • (2009) Proc Natl Acad Sci U S A , vol.106 , Issue.8 , pp. 2886-2891
    • Kaletsky, R.L.1    Francica, J.R.2    Agrawal-Gamse, C.3    Bates, P.4
  • 76
    • 78149348506 scopus 로고    scopus 로고
    • Steric shielding of surface epitopes and impaired immune recognition induced by the ebola virus glycoprotein
    • PID: 20844579
    • Francica JR, Varela-Rohena A, Medvec A, Plesa G, Riley JL, Bates P (2010) Steric shielding of surface epitopes and impaired immune recognition induced by the ebola virus glycoprotein. PLoS Pathog 6(9):e1001098. doi:10.1371/journal.ppat.1001098
    • (2010) PLoS Pathog , vol.6 , Issue.9
    • Francica, J.R.1    Varela-Rohena, A.2    Medvec, A.3    Plesa, G.4    Riley, J.L.5    Bates, P.6
  • 78
    • 13444301373 scopus 로고    scopus 로고
    • Role of Ebola virus secreted glycoproteins and virus-like particles in activation of human macrophages
    • COI: 1:CAS:528:DC%2BD2MXitlejurc%3D, PID: 15681442
    • Wahl-Jensen V, Kurz SK, Hazelton PR, Schnittler HJ, Stroher U, Burton DR, Feldmann H (2005) Role of Ebola virus secreted glycoproteins and virus-like particles in activation of human macrophages. J Virol 79(4):2413–2419. doi:10.1128/JVI.79.4.2413-2419.2005
    • (2005) J Virol , vol.79 , Issue.4 , pp. 2413-2419
    • Wahl-Jensen, V.1    Kurz, S.K.2    Hazelton, P.R.3    Schnittler, H.J.4    Stroher, U.5    Burton, D.R.6    Feldmann, H.7
  • 79
    • 72849134026 scopus 로고    scopus 로고
    • Interaction between Ebola virus glycoprotein and host toll-like receptor 4 leads to induction of proinflammatory cytokines and SOCS1
    • COI: 1:CAS:528:DC%2BC3cXisVKitLw%3D, PID: 19846529
    • Okumura A, Pitha PM, Yoshimura A, Harty RN (2010) Interaction between Ebola virus glycoprotein and host toll-like receptor 4 leads to induction of proinflammatory cytokines and SOCS1. J Virol 84(1):27–33. doi:10.1128/JVI.01462-09
    • (2010) J Virol , vol.84 , Issue.1 , pp. 27-33
    • Okumura, A.1    Pitha, P.M.2    Yoshimura, A.3    Harty, R.N.4
  • 81
    • 0016616634 scopus 로고
    • The pathology of human Lassa fever
    • PID: 1085209
    • Winn WC Jr, Walker DH (1975) The pathology of human Lassa fever. Bull World Health Organ 52(4–6):535–545
    • (1975) Bull World Health Organ , vol.52 , Issue.4-6 , pp. 535-545
    • Winn, W.C.1    Walker, D.H.2
  • 82
    • 1342303468 scopus 로고    scopus 로고
    • Lassa virus infection of human dendritic cells and macrophages is productive but fails to activate cells
    • COI: 1:CAS:528:DC%2BD2cXhsVCrs70%3D, PID: 14978087
    • Baize S, Kaplon J, Faure C, Pannetier D, Georges-Courbot MC, Deubel V (2004) Lassa virus infection of human dendritic cells and macrophages is productive but fails to activate cells. J Immunol 172(5):2861–2869
    • (2004) J Immunol , vol.172 , Issue.5 , pp. 2861-2869
    • Baize, S.1    Kaplon, J.2    Faure, C.3    Pannetier, D.4    Georges-Courbot, M.C.5    Deubel, V.6
  • 84
    • 79961189906 scopus 로고    scopus 로고
    • Human dendritic cells infected with the nonpathogenic Mopeia virus induce stronger T-cell responses than those infected with Lassa virus
    • COI: 1:CAS:528:DC%2BC3MXpvFemtrw%3D, PID: 21632749
    • Pannetier D, Reynard S, Russier M, Journeaux A, Tordo N, Deubel V, Baize S (2011) Human dendritic cells infected with the nonpathogenic Mopeia virus induce stronger T-cell responses than those infected with Lassa virus. J Virol 85(16):8293–8306. doi:10.1128/JVI.02120-10
    • (2011) J Virol , vol.85 , Issue.16 , pp. 8293-8306
    • Pannetier, D.1    Reynard, S.2    Russier, M.3    Journeaux, A.4    Tordo, N.5    Deubel, V.6    Baize, S.7
  • 85
    • 78650132935 scopus 로고    scopus 로고
    • Cap binding and immune evasion revealed by Lassa nucleoprotein structure
    • COI: 1:CAS:528:DC%2BC3cXhsVGhsr3F, PID: 21085117
    • Qi X, Lan S, Wang W, Schelde LM, Dong H, Wallat GD, Ly H, Liang Y, Dong C (2010) Cap binding and immune evasion revealed by Lassa nucleoprotein structure. Nature 468(7325):779–783. doi:10.1038/nature09605
    • (2010) Nature , vol.468 , Issue.7325 , pp. 779-783
    • Qi, X.1    Lan, S.2    Wang, W.3    Schelde, L.M.4    Dong, H.5    Wallat, G.D.6    Ly, H.7    Liang, Y.8    Dong, C.9
  • 86
    • 79952303123 scopus 로고    scopus 로고
    • Structure of the Lassa virus nucleoprotein reveals a dsRNA-specific 3′ to 5′ exonuclease activity essential for immune suppression
    • COI: 1:CAS:528:DC%2BC3MXitFKqurc%3D, PID: 21262835
    • Hastie KM, Kimberlin CR, Zandonatti MA, MacRae IJ, Saphire EO (2011) Structure of the Lassa virus nucleoprotein reveals a dsRNA-specific 3′ to 5′ exonuclease activity essential for immune suppression. Proc Natl Acad Sci U S A 108(6):2396–2401. doi:10.1073/pnas.1016404108
    • (2011) Proc Natl Acad Sci U S A , vol.108 , Issue.6 , pp. 2396-2401
    • Hastie, K.M.1    Kimberlin, C.R.2    Zandonatti, M.A.3    MacRae, I.J.4    Saphire, E.O.5
  • 87
    • 84911386623 scopus 로고    scopus 로고
    • Exonuclease domain of the Lassa virus nucleoprotein is critical to avoid RIG-I signaling and to inhibit the innate immune response
    • PID: 25253344
    • Reynard S, Russier M, Fizet A, Carnec X, Baize S (2014) Exonuclease domain of the Lassa virus nucleoprotein is critical to avoid RIG-I signaling and to inhibit the innate immune response. J Virol 88(23):13923–13927. doi:10.1128/JVI.01923-14
    • (2014) J Virol , vol.88 , Issue.23 , pp. 13923-13927
    • Reynard, S.1    Russier, M.2    Fizet, A.3    Carnec, X.4    Baize, S.5
  • 88
    • 84911399835 scopus 로고    scopus 로고
    • The exonuclease domain of Lassa virus nucleoprotein is involved in antigen-presenting-cell-mediated NK cell responses
    • PID: 25253342
    • Russier M, Reynard S, Carnec X, Baize S (2014) The exonuclease domain of Lassa virus nucleoprotein is involved in antigen-presenting-cell-mediated NK cell responses. J Virol 88(23):13811–13820. doi:10.1128/JVI.01908-14
    • (2014) J Virol , vol.88 , Issue.23 , pp. 13811-13820
    • Russier, M.1    Reynard, S.2    Carnec, X.3    Baize, S.4
  • 89
    • 84923008601 scopus 로고    scopus 로고
    • The Z proteins of pathogenic but not nonpathogenic arenaviruses inhibit RIG-I-like receptor-dependent interferon production
    • PID: 25552708
    • Xing J, Ly H, Liang Y (2015) The Z proteins of pathogenic but not nonpathogenic arenaviruses inhibit RIG-I-like receptor-dependent interferon production. J Virol 89(5):2944–2955. doi:10.1128/JVI.03349-14
    • (2015) J Virol , vol.89 , Issue.5 , pp. 2944-2955
    • Xing, J.1    Ly, H.2    Liang, Y.3
  • 90
    • 75449114628 scopus 로고    scopus 로고
    • Z proteins of New World arenaviruses bind RIG-I and interfere with type I interferon induction
    • COI: 1:CAS:528:DC%2BC3cXhslaqsbw%3D, PID: 20007272
    • Fan L, Briese T, Lipkin WI (2010) Z proteins of New World arenaviruses bind RIG-I and interfere with type I interferon induction. J Virol 84(4):1785–1791. doi:10.1128/JVI.01362-09
    • (2010) J Virol , vol.84 , Issue.4 , pp. 1785-1791
    • Fan, L.1    Briese, T.2    Lipkin, W.I.3
  • 91
    • 84923578569 scopus 로고    scopus 로고
    • Yellow fever
    • PID: 25453327
    • Monath TP, Vasconcelos PF (2015) Yellow fever. J Clin Virol 64:160–173. doi:10.1016/j.jcv.2014.08.030
    • (2015) J Clin Virol , vol.64 , pp. 160-173
    • Monath, T.P.1    Vasconcelos, P.F.2
  • 92
    • 24744463600 scopus 로고    scopus 로고
    • Yellow fever vaccine
    • COI: 1:CAS:528:DC%2BD2MXhtVOltb7F, PID: 16117712
    • Monath TP (2005) Yellow fever vaccine. Expert Rev Vaccines 4(4):553–574. doi:10.1586/14760584.4.4.553
    • (2005) Expert Rev Vaccines , vol.4 , Issue.4 , pp. 553-574
    • Monath, T.P.1
  • 94
    • 0642379621 scopus 로고    scopus 로고
    • Pathogenesis and pathophysiology of yellow fever
    • PID: 14689698
    • Monath TP, Barrett AD (2003) Pathogenesis and pathophysiology of yellow fever. Adv Virus Res 60:343–395
    • (2003) Adv Virus Res , vol.60 , pp. 343-395
    • Monath, T.P.1    Barrett, A.D.2
  • 95
    • 40749108390 scopus 로고    scopus 로고
    • Treatment of yellow fever
    • COI: 1:CAS:528:DC%2BD1cXjtleqtLg%3D, PID: 18061688
    • Monath TP (2008) Treatment of yellow fever. Antivir Res 78(1):116–124. doi:10.1016/j.antiviral.2007.10.009
    • (2008) Antivir Res , vol.78 , Issue.1 , pp. 116-124
    • Monath, T.P.1
  • 96
    • 0035436653 scopus 로고    scopus 로고
    • Yellow fever: an update
    • COI: 1:STN:280:DC%2BD387js1Ohsw%3D%3D, PID: 11871403
    • Monath TP (2001) Yellow fever: an update. Lancet Infect Dis 1(1):11–20. doi:10.1016/S1473-3099(01)00016-0
    • (2001) Lancet Infect Dis , vol.1 , Issue.1 , pp. 11-20
    • Monath, T.P.1
  • 97
    • 20744453948 scopus 로고    scopus 로고
    • Inhibition of alpha/beta interferon signaling by the NS4B protein of flaviviruses
    • COI: 1:CAS:528:DC%2BD2MXlslGjt7s%3D, PID: 15956546
    • Munoz-Jordan JL, Laurent-Rolle M, Ashour J, Martinez-Sobrido L, Ashok M, Lipkin WI, Garcia-Sastre A (2005) Inhibition of alpha/beta interferon signaling by the NS4B protein of flaviviruses. J Virol 79(13):8004–8013. doi:10.1128/JVI.79.13.8004-8013.2005
    • (2005) J Virol , vol.79 , Issue.13 , pp. 8004-8013
    • Munoz-Jordan, J.L.1    Laurent-Rolle, M.2    Ashour, J.3    Martinez-Sobrido, L.4    Ashok, M.5    Lipkin, W.I.6    Garcia-Sastre, A.7
  • 100
    • 0017372280 scopus 로고
    • Effect of a nuclease-resistant derivative of polyriboinosinic-polyribocytidylic acid complex on yellow fever in rhesus monkeys (Macaca mulatta)
    • COI: 1:CAS:528:DyaE1cXivFY%3D, PID: 407312
    • Stephen EL, Sammons ML, Pannier WL, Baron S, Spertzel RO, Levy HB (1977) Effect of a nuclease-resistant derivative of polyriboinosinic-polyribocytidylic acid complex on yellow fever in rhesus monkeys (Macaca mulatta). J Infect Dis 136(1):122–126
    • (1977) J Infect Dis , vol.136 , Issue.1 , pp. 122-126
    • Stephen, E.L.1    Sammons, M.L.2    Pannier, W.L.3    Baron, S.4    Spertzel, R.O.5    Levy, H.B.6
  • 102
    • 0019419111 scopus 로고
    • Pathophysiologic correlations in a rhesus monkey model of yellow fever with special observations on the acute necrosis of B cell areas of lymphoid tissues
    • COI: 1:STN:280:DyaL3M3gsVylug%3D%3D
    • Monath TP, Brinker KR, Chandler FW, Kemp GE, Cropp CB (1981) Pathophysiologic correlations in a rhesus monkey model of yellow fever with special observations on the acute necrosis of B cell areas of lymphoid tissues. AmJTrop Med Hyg 30(2):431–443
    • (1981) AmJTrop Med Hyg , vol.30 , Issue.2 , pp. 431-443
    • Monath, T.P.1    Brinker, K.R.2    Chandler, F.W.3    Kemp, G.E.4    Cropp, C.B.5
  • 106
    • 0029872239 scopus 로고    scopus 로고
    • Filovirus-induced endothelial leakage triggered by infected monocytes/macrophages
    • COI: 1:CAS:528:DyaK28XhslWgt7s%3D, PID: 8642644
    • Feldmann H, Bugany H, Mahner F, Klenk HD, Drenckhahn D, Schnittler HJ (1996) Filovirus-induced endothelial leakage triggered by infected monocytes/macrophages. J Virol 70(4):2208–2214
    • (1996) J Virol , vol.70 , Issue.4 , pp. 2208-2214
    • Feldmann, H.1    Bugany, H.2    Mahner, F.3    Klenk, H.D.4    Drenckhahn, D.5    Schnittler, H.J.6
  • 107
    • 24944465690 scopus 로고    scopus 로고
    • Ebola virus: new insights into disease aetiopathology and possible therapeutic interventions
    • PID: 15383160
    • Geisbert TW, Hensley LE (2004) Ebola virus: new insights into disease aetiopathology and possible therapeutic interventions. Expert Rev Mol Med 6(20):1–24
    • (2004) Expert Rev Mol Med , vol.6 , Issue.20 , pp. 1-24
    • Geisbert, T.W.1    Hensley, L.E.2
  • 108
    • 0348053693 scopus 로고    scopus 로고
    • Mechanisms underlying coagulation abnormalities in ebola hemorrhagic fever: overexpression of tissue factor in primate monocytes/macrophages is a key event
    • COI: 1:CAS:528:DC%2BD2cXktlOisA%3D%3D, PID: 14639531
    • Geisbert TW, Young HA, Jahrling PB, Davis KJ, Kagan E, Hensley LE (2003) Mechanisms underlying coagulation abnormalities in ebola hemorrhagic fever: overexpression of tissue factor in primate monocytes/macrophages is a key event. J Infect Dis 188(11):1618–1629
    • (2003) J Infect Dis , vol.188 , Issue.11 , pp. 1618-1629
    • Geisbert, T.W.1    Young, H.A.2    Jahrling, P.B.3    Davis, K.J.4    Kagan, E.5    Hensley, L.E.6
  • 109
    • 77952708376 scopus 로고    scopus 로고
    • Are we any closer to combating Ebola infections?
    • PID: 20511001
    • Feldmann H (2010) Are we any closer to combating Ebola infections? Lancet 375(9729):1850–1852. doi:10.1016/S0140-6736(10)60597-1
    • (2010) Lancet , vol.375 , Issue.9729 , pp. 1850-1852
    • Feldmann, H.1
  • 110
    • 0034066642 scopus 로고    scopus 로고
    • Apoptosis in fatal Ebola infection. Does the virus toll the bell for immune system?
    • COI: 1:CAS:528:DC%2BD3cXisFShtbk%3D, PID: 11227491
    • Baize S, Leroy EM, Mavoungou E, Fisher-Hoch SP (2000) Apoptosis in fatal Ebola infection. Does the virus toll the bell for immune system? Apoptosis 5(1):5–7
    • (2000) Apoptosis , vol.5 , Issue.1 , pp. 5-7
    • Baize, S.1    Leroy, E.M.2    Mavoungou, E.3    Fisher-Hoch, S.P.4
  • 112
    • 44849135333 scopus 로고    scopus 로고
    • Functional CD8+ T cell responses in lethal Ebola virus infection
    • COI: 1:CAS:528:DC%2BD1cXisl2jtr8%3D, PID: 18322215
    • Bradfute SB, Warfield KL, Bavari S (2008) Functional CD8+ T cell responses in lethal Ebola virus infection. J Immunol 180(6):4058–4066
    • (2008) J Immunol , vol.180 , Issue.6 , pp. 4058-4066
    • Bradfute, S.B.1    Warfield, K.L.2    Bavari, S.3


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