Differential Regulation of Interferon Responses by Ebola and Marburg Virus VP35 Proteins

Cell Reports

Volumn 14, Issue 7, 2016, Pages 1632-1640

  Edwards, Megan R ^a,b   Liu, Gai ^b   Mire, Chad E ^c   Sureshchandra, Suhas ^d   Luthra, Priya ^a   Yen, Benjamin ^a   Shabman, Reed S ^a,e   Leung, Daisy W ^b   Messaoudi, Ilhem ^d   Geisbert, Thomas W ^c   Amarasinghe, Gaya K ^b   Basler, Christopher F ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c University of Texas Medical Branch School of Medicine   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e J CRAIG VENTER INSTITUTE   (United States)

Author keywords

Filovirus; Immune evasion; Pattern associated molecular pattern (PAMP); RIG I like receptor; Type I interferon; VP35

Indexed keywords

DOUBLE STRANDED RNA; INTERFERON; PROTEIN VP35; RETINOIC ACID INDUCIBLE PROTEIN I; UNCLASSIFIED DRUG; VIRUS PROTEIN; VIRUS RNA; ALPHA INTERFERON; BETA INTERFERON; DDX58 PROTEIN, HUMAN; DEAD BOX PROTEIN; PROTEIN BINDING; VIRAL PROTEIN; VP35 PROTEIN, FILOVIRUS;

ARTICLE; BINDING AFFINITY; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; CYTOKINE PRODUCTION; EBOLAVIRUS; FILOVIRUS INFECTION; HEK293 CELL LINE; INNATE IMMUNITY; MARBURGVIRUS; MARBURGVIRUS INFECTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN RNA BINDING; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; UPREGULATION; WESTERN BLOTTING; AMINO ACID SEQUENCE; ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; CELL LINE; CHEMISTRY; GENE EXPRESSION REGULATION; GENETICS; HOST PATHOGEN INTERACTION; HUMAN; IMMUNOLOGY; MOLECULAR GENETICS; MOLECULAR MODEL; MONOCYTE; PROTEIN SECONDARY STRUCTURE; PROTEIN TERTIARY STRUCTURE; SEQUENCE ALIGNMENT; SPECIES DIFFERENCE;

AMINO ACID SEQUENCE; CELL LINE; DEAD BOX PROTEIN 58; DEAD-BOX RNA HELICASES; EBOLAVIRUS; GENE EXPRESSION REGULATION; HOST-PATHOGEN INTERACTIONS; HUMANS; INTERFERON-ALPHA; INTERFERON-BETA; MARBURGVIRUS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MONOCYTES; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; RNA, DOUBLE-STRANDED; SEQUENCE ALIGNMENT; SIGNAL TRANSDUCTION; SPECIES SPECIFICITY; VIRAL REGULATORY AND ACCESSORY PROTEINS;

EID: 84959115944     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2016.01.049     Document Type: Article

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