메뉴 건너뛰기




Volumn 95, Issue 9, 2017, Pages 915-925

Purinergic signaling during intestinal inflammation

Author keywords

Adaptive immunity; Adenosine; AHR; ATP; CD39; CD73; ENPP; ENTPD; Extracellular nucleotides; Inflammation; Inflammatory bowel disease; Innate immunity; Lymphocytes; Macrophages; P1 receptors; P2 receptors

Indexed keywords

AROMATIC HYDROCARBON RECEPTOR; BILIRUBIN; CD39 ANTIGEN; HYPOXIA INDUCIBLE FACTOR 1ALPHA; PURINERGIC RECEPTOR; ADENOSINE; APYRASE; BIOLOGICAL MARKER; LEUKOCYTE ANTIGEN; PURINE DERIVATIVE;

EID: 85019686803     PISSN: 09462716     EISSN: 14321440     Source Type: Journal    
DOI: 10.1007/s00109-017-1545-1     Document Type: Review
Times cited : (77)

References (73)
  • 1
    • 84871048026 scopus 로고    scopus 로고
    • Purinergic signaling during inflammation
    • COI: 1:CAS:528:DC%2BC38XhvVKmt77L, PID: 23234515
    • Eltzschig HK, Sitkovsky MV, Robson SC (2012) Purinergic signaling during inflammation. N Engl J Med 367:2322–2333
    • (2012) N Engl J Med , vol.367 , pp. 2322-2333
    • Eltzschig, H.K.1    Sitkovsky, M.V.2    Robson, S.C.3
  • 2
    • 84874000718 scopus 로고    scopus 로고
    • Biological functions of ecto-enzymes in regulating extracellular adenosine levels in neoplastic and inflammatory disease states
    • COI: 1:CAS:528:DC%2BC3sXhvFyjsbY%3D
    • Longhi MS, Robson SC, Bernstein SH, Serra S, Deaglio S (2013) Biological functions of ecto-enzymes in regulating extracellular adenosine levels in neoplastic and inflammatory disease states. J Mol Med (Berl) 91:165–172
    • (2013) J Mol Med (Berl) , vol.91 , pp. 165-172
    • Longhi, M.S.1    Robson, S.C.2    Bernstein, S.H.3    Serra, S.4    Deaglio, S.5
  • 3
    • 84969641306 scopus 로고    scopus 로고
    • Regulation of the T cell response by CD39
    • COI: 1:CAS:528:DC%2BC28XnvFShur0%3D, PID: 27236363
    • Takenaka MC, Robson S, Quintana FJ (2016) Regulation of the T cell response by CD39. Trends Immunol 37:427–439
    • (2016) Trends Immunol , vol.37 , pp. 427-439
    • Takenaka, M.C.1    Robson, S.2    Quintana, F.J.3
  • 4
    • 85014351169 scopus 로고    scopus 로고
    • The ectonucleotidases CD39 and CD73: novel checkpoint inhibitor targets
    • COI: 1:CAS:528:DC%2BC2sXjs1eltL8%3D, PID: 28258700
    • Allard B, Longhi MS, Robson SC, Stagg J (2017) The ectonucleotidases CD39 and CD73: novel checkpoint inhibitor targets. Immunol Rev 276:121–144
    • (2017) Immunol Rev , vol.276 , pp. 121-144
    • Allard, B.1    Longhi, M.S.2    Robson, S.C.3    Stagg, J.4
  • 5
    • 0024588769 scopus 로고
    • Origin, metabolism and function of extracellular adenine nucleotides in the blood
    • COI: 1:STN:280:DyaL1M3hslOisQ%3D%3D, PID: 2651791, [published erratum appears in Klin Wochenschr 1989 May 15;67(10):558] review
    • Luthje J (1989) Origin, metabolism and function of extracellular adenine nucleotides in the blood [published erratum appears in Klin Wochenschr 1989 May 15;67(10):558]. [review]. Klin Wochenschr 67:317–327
    • (1989) Klin Wochenschr , vol.67 , pp. 317-327
    • Luthje, J.1
  • 6
    • 9144269934 scopus 로고    scopus 로고
    • Cellular distribution and functions of P2 receptor subtypes in different systems
    • COI: 1:CAS:528:DC%2BD2MXos1SltA%3D%3D, PID: 15548415
    • Burnstock G, Knight G (2004) Cellular distribution and functions of P2 receptor subtypes in different systems. Int Rev Cytol 240:31–304
    • (2004) Int Rev Cytol , vol.240 , pp. 31-304
    • Burnstock, G.1    Knight, G.2
  • 7
    • 0036118418 scopus 로고    scopus 로고
    • Purinergic signaling and vascular cell proliferation and death
    • PID: 11884276
    • Burnstock G (2002) Purinergic signaling and vascular cell proliferation and death. Arterioscler Thromb Vasc Biol 22:364–373
    • (2002) Arterioscler Thromb Vasc Biol , vol.22 , pp. 364-373
    • Burnstock, G.1
  • 8
    • 0031933227 scopus 로고    scopus 로고
    • Ecto-enzyme and signaling functions of lymphocyte CD73
    • COI: 1:CAS:528:DyaK1cXitlyms7k%3D, PID: 9553767
    • Resta R, Yamashita Y, Thompson LF (1998) Ecto-enzyme and signaling functions of lymphocyte CD73. Immunol Rev 161:95–109
    • (1998) Immunol Rev , vol.161 , pp. 95-109
    • Resta, R.1    Yamashita, Y.2    Thompson, L.F.3
  • 9
    • 33846436678 scopus 로고    scopus 로고
    • The E-NTPDase family of ecto-nucleotidases: structure function relationshhips and pathophysiological significance
    • COI: 1:CAS:528:DC%2BD28XhtVKns7fN, PID: 18404480
    • Robson SC, Sevigny J, Zimmermann H (2006) The E-NTPDase family of ecto-nucleotidases: structure function relationshhips and pathophysiological significance. Purinergic Signal 2:409–430
    • (2006) Purinergic Signal , vol.2 , pp. 409-430
    • Robson, S.C.1    Sevigny, J.2    Zimmermann, H.3
  • 10
    • 38449107681 scopus 로고    scopus 로고
    • The role of purinergic signaling in the liver and in transplantation: effects of extracellular nucleotides on hepatic graft vascular injury, rejection and metabolism
    • PID: 17981736
    • Beldi G, Enjyoji K, Wu Y, Miller L, Banz Y, Sun X, Robson SC (2008) The role of purinergic signaling in the liver and in transplantation: effects of extracellular nucleotides on hepatic graft vascular injury, rejection and metabolism. Front Biosci 13:2588–2603
    • (2008) Front Biosci , vol.13 , pp. 2588-2603
    • Beldi, G.1    Enjyoji, K.2    Wu, Y.3    Miller, L.4    Banz, Y.5    Sun, X.6    Robson, S.C.7
  • 12
    • 84959559428 scopus 로고    scopus 로고
    • Purinergic regulation of the immune system
    • COI: 1:CAS:528:DC%2BC28XjtlKmurg%3D, PID: 26922909
    • Cekic C, Linden J (2016) Purinergic regulation of the immune system. Nat Rev Immunol 16:177–192
    • (2016) Nat Rev Immunol , vol.16 , pp. 177-192
    • Cekic, C.1    Linden, J.2
  • 13
    • 34250351459 scopus 로고    scopus 로고
    • Adenosine generation catalyzed by CD39 and CD73 expressed on regulatory T cells mediates immune suppression
    • COI: 1:CAS:528:DC%2BD2sXms1aktrs%3D, PID: 17502665
    • Deaglio S, Dwyer KM, Gao W, Friedman D, Usheva A, Erat A, Chen JF, Enjyoji K, Linden J, Oukka M et al (2007) Adenosine generation catalyzed by CD39 and CD73 expressed on regulatory T cells mediates immune suppression. J Exp Med 204:1257–1265
    • (2007) J Exp Med , vol.204 , pp. 1257-1265
    • Deaglio, S.1    Dwyer, K.M.2    Gao, W.3    Friedman, D.4    Usheva, A.5    Erat, A.6    Chen, J.F.7    Enjyoji, K.8    Linden, J.9    Oukka, M.10
  • 15
    • 84887013719 scopus 로고    scopus 로고
    • TLR stimulation initiates a CD39-based autoregulatory mechanism that limits macrophage inflammatory responses
    • COI: 1:CAS:528:DC%2BC3sXhsV2kt77P, PID: 23908469
    • Cohen HB, Briggs KT, Marino JP, Ravid K, Robson SC, Mosser DM (2013) TLR stimulation initiates a CD39-based autoregulatory mechanism that limits macrophage inflammatory responses. Blood 122:1935–1945
    • (2013) Blood , vol.122 , pp. 1935-1945
    • Cohen, H.B.1    Briggs, K.T.2    Marino, J.P.3    Ravid, K.4    Robson, S.C.5    Mosser, D.M.6
  • 16
    • 84895530996 scopus 로고    scopus 로고
    • Characterization of human CD39+ Th17 cells with suppressor activity and modulation in inflammatory bowel disease
    • PID: 24505337
    • Longhi MS, Moss A, Bai A, Wu Y, Huang H, Cheifetz A, Quintana FJ, Robson SC (2014) Characterization of human CD39+ Th17 cells with suppressor activity and modulation in inflammatory bowel disease. PLoS One 9:e87956
    • (2014) PLoS One , vol.9
    • Longhi, M.S.1    Moss, A.2    Bai, A.3    Wu, Y.4    Huang, H.5    Cheifetz, A.6    Quintana, F.J.7    Robson, S.C.8
  • 17
    • 0031283479 scopus 로고    scopus 로고
    • Inosine binds to A3 adenosine receptors and stimulates mast cell degranulation
    • COI: 1:CAS:528:DyaK2sXotVehtr0%3D, PID: 9389751
    • Jin X, Shepherd RK, Duling BR, Linden J (1997) Inosine binds to A3 adenosine receptors and stimulates mast cell degranulation. J Clin Invest 100:2849–2857
    • (1997) J Clin Invest , vol.100 , pp. 2849-2857
    • Jin, X.1    Shepherd, R.K.2    Duling, B.R.3    Linden, J.4
  • 18
    • 85012233026 scopus 로고    scopus 로고
    • Involvement of adenosine A3 receptors in the chemotactic navigation of macrophages towards apoptotic cells
    • COI: 1:CAS:528:DC%2BC2sXisV2jtbo%3D, PID: 28188820
    • Joos G, Jakim J, Kiss B, Szamosi R, Papp T, Felszeghy S, Saghy T, Nagy G, Szondy Z (2017) Involvement of adenosine A3 receptors in the chemotactic navigation of macrophages towards apoptotic cells. Immunol Lett 183:62–72
    • (2017) Immunol Lett , vol.183 , pp. 62-72
    • Joos, G.1    Jakim, J.2    Kiss, B.3    Szamosi, R.4    Papp, T.5    Felszeghy, S.6    Saghy, T.7    Nagy, G.8    Szondy, Z.9
  • 19
    • 68949186253 scopus 로고    scopus 로고
    • Extracellular nucleotides as negative modulators of immunity
    • COI: 1:CAS:528:DC%2BD1MXhtVenurfP, PID: 19628431
    • Di Virgilio F, Boeynaems JM, Robson SC (2009) Extracellular nucleotides as negative modulators of immunity. Curr Opin Pharmacol 9:507–513
    • (2009) Curr Opin Pharmacol , vol.9 , pp. 507-513
    • Di Virgilio, F.1    Boeynaems, J.M.2    Robson, S.C.3
  • 20
    • 84872132330 scopus 로고    scopus 로고
    • Disordered purinergic signaling and abnormal cellular metabolism are associated with development of liver cancer in Cd39/ENTPD1 null mice
    • COI: 1:CAS:528:DC%2BC3sXms12hug%3D%3D, PID: 22859060
    • Sun X, Han L, Seth P, Bian S, Li L, Csizmadia E, Junger WG, Schmelzle M, Usheva A, Tapper EB et al (2013) Disordered purinergic signaling and abnormal cellular metabolism are associated with development of liver cancer in Cd39/ENTPD1 null mice. Hepatology 57:205–216
    • (2013) Hepatology , vol.57 , pp. 205-216
    • Sun, X.1    Han, L.2    Seth, P.3    Bian, S.4    Li, L.5    Csizmadia, E.6    Junger, W.G.7    Schmelzle, M.8    Usheva, A.9    Tapper, E.B.10
  • 21
    • 0032547062 scopus 로고    scopus 로고
    • A novel response to dioxin. Induction of ecto-ATPase gene expression
    • COI: 1:CAS:528:DyaK1cXktVSmtrY%3D, PID: 9624117
    • Gao L, Dong L, Whitlock JP Jr (1998) A novel response to dioxin. Induction of ecto-ATPase gene expression. J Biol Chem 273:15358–15365
    • (1998) J Biol Chem , vol.273 , pp. 15358-15365
    • Gao, L.1    Dong, L.2    Whitlock, J.P.3
  • 22
    • 77955859470 scopus 로고    scopus 로고
    • Activation of the aryl hydrocarbon receptor induces human type 1 regulatory T cell-like and Foxp3(+) regulatory T cells
    • COI: 1:CAS:528:DC%2BC3cXpsFWks70%3D, PID: 20676092
    • Gandhi R, Kumar D, Burns EJ, Nadeau M, Dake B, Laroni A, Kozoriz D, Weiner HL, Quintana FJ (2010) Activation of the aryl hydrocarbon receptor induces human type 1 regulatory T cell-like and Foxp3(+) regulatory T cells. Nat Immunol 11:846–853
    • (2010) Nat Immunol , vol.11 , pp. 846-853
    • Gandhi, R.1    Kumar, D.2    Burns, E.J.3    Nadeau, M.4    Dake, B.5    Laroni, A.6    Kozoriz, D.7    Weiner, H.L.8    Quintana, F.J.9
  • 23
    • 84886728752 scopus 로고    scopus 로고
    • IL-27 acts on DCs to suppress the T cell response and autoimmunity by inducing expression of the immunoregulatory molecule CD39
    • COI: 1:CAS:528:DC%2BC3sXhtlGltL7I, PID: 23995234
    • Mascanfroni ID, Yeste A, Vieira SM, Burns EJ, Patel B, Sloma I, Wu Y, Mayo L, Ben-Hamo R, Efroni S et al (2013) IL-27 acts on DCs to suppress the T cell response and autoimmunity by inducing expression of the immunoregulatory molecule CD39. Nat Immunol 14:1054–1063
    • (2013) Nat Immunol , vol.14 , pp. 1054-1063
    • Mascanfroni, I.D.1    Yeste, A.2    Vieira, S.M.3    Burns, E.J.4    Patel, B.5    Sloma, I.6    Wu, Y.7    Mayo, L.8    Ben-Hamo, R.9    Efroni, S.10
  • 24
    • 77951649299 scopus 로고    scopus 로고
    • SP1-dependent induction of CD39 facilitates hepatic ischemic preconditioning
    • COI: 1:CAS:528:DC%2BC3cXjs1Wqs78%3D, PID: 20207994
    • Hart ML, Gorzolla IC, Schittenhelm J, Robson SC, Eltzschig HK (2010) SP1-dependent induction of CD39 facilitates hepatic ischemic preconditioning. J Immunol 184:4017–4024
    • (2010) J Immunol , vol.184 , pp. 4017-4024
    • Hart, M.L.1    Gorzolla, I.C.2    Schittenhelm, J.3    Robson, S.C.4    Eltzschig, H.K.5
  • 25
    • 79954994463 scopus 로고    scopus 로고
    • Hypoxia-inducible factor-1alpha-dependent protection from intestinal ischemia/reperfusion injury involves ecto-5′-nucleotidase (CD73) and the A2B adenosine receptor
    • COI: 1:CAS:528:DC%2BC3MXjvVKlsrg%3D, PID: 21357264
    • Hart ML, Grenz A, Gorzolla IC, Schittenhelm J, Dalton JH, Eltzschig HK (2011) Hypoxia-inducible factor-1alpha-dependent protection from intestinal ischemia/reperfusion injury involves ecto-5′-nucleotidase (CD73) and the A2B adenosine receptor. J Immunol 186:4367–4374
    • (2011) J Immunol , vol.186 , pp. 4367-4374
    • Hart, M.L.1    Grenz, A.2    Gorzolla, I.C.3    Schittenhelm, J.4    Dalton, J.H.5    Eltzschig, H.K.6
  • 26
    • 84878620093 scopus 로고    scopus 로고
    • Attenuating myocardial ischemia by targeting A2B adenosine receptors
    • COI: 1:CAS:528:DC%2BC3sXkvF2qtLg%3D, PID: 23540714
    • Eltzschig HK, Bonney SK, Eckle T (2013) Attenuating myocardial ischemia by targeting A2B adenosine receptors. Trends Mol Med 19:345–354
    • (2013) Trends Mol Med , vol.19 , pp. 345-354
    • Eltzschig, H.K.1    Bonney, S.K.2    Eckle, T.3
  • 27
    • 84860663922 scopus 로고    scopus 로고
    • Adora2b-elicited Per2 stabilization promotes a HIF-dependent metabolic switch crucial for myocardial adaptation to ischemia
    • COI: 1:CAS:528:DC%2BC38XlsFSqsrY%3D, PID: 22504483
    • Eckle T, Hartmann K, Bonney S, Reithel S, Mittelbronn M, Walker LA, Lowes BD, Han J, Borchers CH, Buttrick PM et al (2012) Adora2b-elicited Per2 stabilization promotes a HIF-dependent metabolic switch crucial for myocardial adaptation to ischemia. Nat Med 18:774–782
    • (2012) Nat Med , vol.18 , pp. 774-782
    • Eckle, T.1    Hartmann, K.2    Bonney, S.3    Reithel, S.4    Mittelbronn, M.5    Walker, L.A.6    Lowes, B.D.7    Han, J.8    Borchers, C.H.9    Buttrick, P.M.10
  • 28
    • 84872940943 scopus 로고    scopus 로고
    • Adenosine A2A receptor and TNF-alpha regulate the circadian machinery of the human monocytic THP-1 cells
    • COI: 1:CAS:528:DC%2BC3sXhs1Ohs7c%3D, PID: 22923002
    • Perez-Aso M, Feig JL, Mediero A, Cronstein BN (2013) Adenosine A2A receptor and TNF-alpha regulate the circadian machinery of the human monocytic THP-1 cells. Inflammation 36:152–162
    • (2013) Inflammation , vol.36 , pp. 152-162
    • Perez-Aso, M.1    Feig, J.L.2    Mediero, A.3    Cronstein, B.N.4
  • 29
    • 84991490324 scopus 로고    scopus 로고
    • Northern latitude but not season is associated with increased rates of hospitalizations related to inflammatory bowel disease: results of a multi-year analysis of a national cohort
    • PID: 27579718
    • Stein AC, Gaetano JN, Jacobs J, Kunnavakkam R, Bissonnette M, Pekow J (2016) Northern latitude but not season is associated with increased rates of hospitalizations related to inflammatory bowel disease: results of a multi-year analysis of a national cohort. PLoS One 11:e0161523
    • (2016) PLoS One , vol.11
    • Stein, A.C.1    Gaetano, J.N.2    Jacobs, J.3    Kunnavakkam, R.4    Bissonnette, M.5    Pekow, J.6
  • 31
    • 84886745461 scopus 로고    scopus 로고
    • The molecular basis for the immunomodulatory activities of unconjugated bilirubin
    • COI: 1:CAS:528:DC%2BC3sXhsl2lsr3M, PID: 24144577
    • Jangi S, Otterbein L, Robson S (2013) The molecular basis for the immunomodulatory activities of unconjugated bilirubin. Int J Biochem Cell Biol 45:2843–2851
    • (2013) Int J Biochem Cell Biol , vol.45 , pp. 2843-2851
    • Jangi, S.1    Otterbein, L.2    Robson, S.3
  • 34
    • 33747785278 scopus 로고    scopus 로고
    • Cutting edge: critical role for A2A adenosine receptors in the T cell-mediated regulation of colitis
    • COI: 1:CAS:528:DC%2BD28Xot1equ7g%3D, PID: 16920910
    • Naganuma M, Wiznerowicz EB, Lappas CM, Linden J, Worthington MT, Ernst PB (2006) Cutting edge: critical role for A2A adenosine receptors in the T cell-mediated regulation of colitis. J Immunol 177:2765–2769
    • (2006) J Immunol , vol.177 , pp. 2765-2769
    • Naganuma, M.1    Wiznerowicz, E.B.2    Lappas, C.M.3    Linden, J.4    Worthington, M.T.5    Ernst, P.B.6
  • 35
    • 65249138361 scopus 로고    scopus 로고
    • Contribution of adenosine A2B receptors to inflammatory parameters of experimental colitis
    • COI: 1:CAS:528:DC%2BD1MXjvFOisrw%3D, PID: 19342675
    • Frick JS, MacManus CF, Scully M, Glover LE, Eltzschig HK, Colgan SP (2009) Contribution of adenosine A2B receptors to inflammatory parameters of experimental colitis. J Immunol 182:4957–4964
    • (2009) J Immunol , vol.182 , pp. 4957-4964
    • Frick, J.S.1    MacManus, C.F.2    Scully, M.3    Glover, L.E.4    Eltzschig, H.K.5    Colgan, S.P.6
  • 37
    • 70349745514 scopus 로고    scopus 로고
    • From the cover: CD39 deletion exacerbates experimental murine colitis and human polymorphisms increase susceptibility to inflammatory bowel disease
    • COI: 1:CAS:528:DC%2BD1MXht1Ogs73I, PID: 19805374
    • Friedman DJ, Kunzli BM, Yi AR, Sevigny J, Berberat PO, Enjyoji K, Csizmadia E, Friess H, Robson SC (2009) From the cover: CD39 deletion exacerbates experimental murine colitis and human polymorphisms increase susceptibility to inflammatory bowel disease. Proc Natl Acad Sci U S A 106:16788–16793
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 16788-16793
    • Friedman, D.J.1    Kunzli, B.M.2    Yi, A.R.3    Sevigny, J.4    Berberat, P.O.5    Enjyoji, K.6    Csizmadia, E.7    Friess, H.8    Robson, S.C.9
  • 40
    • 85008354915 scopus 로고    scopus 로고
    • Innate and adaptive immune traits are differentially affected by genetic and environmental factors
    • COI: 1:CAS:528:DC%2BC2sXmsVCjtQ%3D%3D, PID: 28054551
    • Mangino M, Roederer M, Beddall MH, Nestle FO, Spector TD (2017) Innate and adaptive immune traits are differentially affected by genetic and environmental factors. Nat Commun 8:13850
    • (2017) Nat Commun , vol.8 , pp. 13850
    • Mangino, M.1    Roederer, M.2    Beddall, M.H.3    Nestle, F.O.4    Spector, T.D.5
  • 41
    • 84976332562 scopus 로고    scopus 로고
    • Luminal extracellular vesicles (EVs) in inflammatory bowel disease (IBD) exhibit proinflammatory effects on epithelial cells and macrophages
    • PID: 27271497
    • Mitsuhashi S, Feldbrugge L, Csizmadia E, Mitsuhashi M, Robson SC, Moss AC (2016) Luminal extracellular vesicles (EVs) in inflammatory bowel disease (IBD) exhibit proinflammatory effects on epithelial cells and macrophages. Inflamm Bowel Dis 22:1587–1595
    • (2016) Inflamm Bowel Dis , vol.22 , pp. 1587-1595
    • Mitsuhashi, S.1    Feldbrugge, L.2    Csizmadia, E.3    Mitsuhashi, M.4    Robson, S.C.5    Moss, A.C.6
  • 43
    • 47649107368 scopus 로고    scopus 로고
    • CD39 is incorporated into plasma microparticles where it maintains functional properties and impacts endothelial activation
    • COI: 1:CAS:528:DC%2BD1cXhtV2qsLbI, PID: 18537971
    • Banz Y, Beldi G, Wu Y, Atkinson B, Usheva A, Robson SC (2008) CD39 is incorporated into plasma microparticles where it maintains functional properties and impacts endothelial activation. Br J Haematol 142:627–637
    • (2008) Br J Haematol , vol.142 , pp. 627-637
    • Banz, Y.1    Beldi, G.2    Wu, Y.3    Atkinson, B.4    Usheva, A.5    Robson, S.C.6
  • 44
    • 33645738564 scopus 로고    scopus 로고
    • Reconstitution of CD39 in liposomes amplifies nucleoside triphosphate diphosphohydrolase activity and restores thromboregulatory properties
    • PID: 16616242
    • Haller CA, Cui W, Wen J, Robson SC, Chaikof EL (2006) Reconstitution of CD39 in liposomes amplifies nucleoside triphosphate diphosphohydrolase activity and restores thromboregulatory properties. J Vasc Surg 43:816–823
    • (2006) J Vasc Surg , vol.43 , pp. 816-823
    • Haller, C.A.1    Cui, W.2    Wen, J.3    Robson, S.C.4    Chaikof, E.L.5
  • 50
    • 57349100406 scopus 로고    scopus 로고
    • Possible effects of microbial ecto-nucleoside triphosphate diphosphohydrolases on host-pathogen interactions
    • COI: 1:CAS:528:DC%2BD1MXps1Gkuw%3D%3D, PID: 19052327, table of contents
    • Sansom FM, Robson SC, Hartland EL (2008) Possible effects of microbial ecto-nucleoside triphosphate diphosphohydrolases on host-pathogen interactions. Microbiol Mol Biol Rev 72:765–781 table of contents
    • (2008) Microbiol Mol Biol Rev , vol.72 , pp. 765-781
    • Sansom, F.M.1    Robson, S.C.2    Hartland, E.L.3
  • 55
    • 84872203428 scopus 로고    scopus 로고
    • Ecto-nucleoside triphosphate diphosphohydrolase 7 controls Th17 cell responses through regulation of luminal ATP in the small intestine
    • COI: 1:CAS:528:DC%2BC3sXjtlGlsg%3D%3D, PID: 23241884
    • Kusu T, Kayama H, Kinoshita M, Jeon SG, Ueda Y, Goto Y, Okumura R, Saiga H, Kurakawa T, Ikeda K et al (2013) Ecto-nucleoside triphosphate diphosphohydrolase 7 controls Th17 cell responses through regulation of luminal ATP in the small intestine. J Immunol 190:774–783
    • (2013) J Immunol , vol.190 , pp. 774-783
    • Kusu, T.1    Kayama, H.2    Kinoshita, M.3    Jeon, S.G.4    Ueda, Y.5    Goto, Y.6    Okumura, R.7    Saiga, H.8    Kurakawa, T.9    Ikeda, K.10
  • 56
    • 84861529229 scopus 로고    scopus 로고
    • Cellular function and molecular structure of ecto-nucleotidases
    • COI: 1:CAS:528:DC%2BC38XnsVCmtbg%3D, PID: 22555564
    • Zimmermann H, Zebisch M, Strater N (2012) Cellular function and molecular structure of ecto-nucleotidases. Purinergic Signal 8:437–502
    • (2012) Purinergic Signal , vol.8 , pp. 437-502
    • Zimmermann, H.1    Zebisch, M.2    Strater, N.3
  • 57
    • 0033563017 scopus 로고    scopus 로고
    • Functional characterization of rat ecto-ATPase and ecto-ATP diphosphohydrolase after heterologous expression in CHO cells
    • COI: 1:CAS:528:DyaK1MXjsVyqtrY%3D, PID: 10231370
    • Heine P, Braun N, Heilbronn A, Zimmermann H (1999) Functional characterization of rat ecto-ATPase and ecto-ATP diphosphohydrolase after heterologous expression in CHO cells. Eur J Biochem 262:102–107
    • (1999) Eur J Biochem , vol.262 , pp. 102-107
    • Heine, P.1    Braun, N.2    Heilbronn, A.3    Zimmermann, H.4
  • 60
    • 31144457368 scopus 로고    scopus 로고
    • Immunolocalization of ecto-nucleoside triphosphate diphosphohydrolase 3 in rat brain: implications for modulation of multiple homeostatic systems including feeding and sleep-wake behaviors
    • COI: 1:CAS:528:DC%2BD28Xos1eksw%3D%3D, PID: 16338080
    • Belcher SM, Zsarnovszky A, Crawford PA, Hemani H, Spurling L, Kirley TL (2006) Immunolocalization of ecto-nucleoside triphosphate diphosphohydrolase 3 in rat brain: implications for modulation of multiple homeostatic systems including feeding and sleep-wake behaviors. Neuroscience 137:1331–1346
    • (2006) Neuroscience , vol.137 , pp. 1331-1346
    • Belcher, S.M.1    Zsarnovszky, A.2    Crawford, P.A.3    Hemani, H.4    Spurling, L.5    Kirley, T.L.6
  • 61
    • 84938746446 scopus 로고    scopus 로고
    • Impact of ectonucleotidases in autonomic nervous functions
    • COI: 1:CAS:528:DC%2BC2MXosFCisbg%3D, PID: 26008223
    • Cardoso AM, Schetinger MR, Correia-de-Sa P, Sevigny J (2015) Impact of ectonucleotidases in autonomic nervous functions. Auton Neurosci 191:25–38
    • (2015) Auton Neurosci , vol.191 , pp. 25-38
    • Cardoso, A.M.1    Schetinger, M.R.2    Correia-de-Sa, P.3    Sevigny, J.4
  • 62
    • 1042291303 scopus 로고    scopus 로고
    • Association of the ecto-ATPase NTPDase2 with glial cells of the peripheral nervous system
    • PID: 14730706
    • Braun N, Sevigny J, Robson SC, Hammer K, Hanani M, Zimmermann H (2004) Association of the ecto-ATPase NTPDase2 with glial cells of the peripheral nervous system. Glia 45:124–132
    • (2004) Glia , vol.45 , pp. 124-132
    • Braun, N.1    Sevigny, J.2    Robson, S.C.3    Hammer, K.4    Hanani, M.5    Zimmermann, H.6
  • 64
    • 84955567315 scopus 로고    scopus 로고
    • Neuro-immune interactions drive tissue programming in intestinal macrophages
    • COI: 1:CAS:528:DC%2BC28XhtV2qu7w%3D, PID: 26777404
    • Gabanyi I, Muller PA, Feighery L, Oliveira TY, Costa-Pinto FA, Mucida D (2016) Neuro-immune interactions drive tissue programming in intestinal macrophages. Cell 164:378–391
    • (2016) Cell , vol.164 , pp. 378-391
    • Gabanyi, I.1    Muller, P.A.2    Feighery, L.3    Oliveira, T.Y.4    Costa-Pinto, F.A.5    Mucida, D.6
  • 65
    • 84859727440 scopus 로고    scopus 로고
    • Purinergic neuromuscular transmission is absent in the colon of P2Y(1) knocked out mice
    • COI: 1:CAS:528:DC%2BC38XntFyksLc%3D, PID: 22371472
    • Gallego D, Gil V, Martinez-Cutillas M, Mane N, Martin MT, Jimenez M (2012) Purinergic neuromuscular transmission is absent in the colon of P2Y(1) knocked out mice. J Physiol 590:1943–1956
    • (2012) J Physiol , vol.590 , pp. 1943-1956
    • Gallego, D.1    Gil, V.2    Martinez-Cutillas, M.3    Mane, N.4    Martin, M.T.5    Jimenez, M.6
  • 66
    • 0036460817 scopus 로고    scopus 로고
    • Ligand-gated ion channels in the enteric nervous system
    • COI: 1:STN:280:DC%2BD38jgtlaqtw%3D%3D, PID: 12464083
    • Galligan JJ (2002) Ligand-gated ion channels in the enteric nervous system. Neurogastroenterol Motil 14:611–623
    • (2002) Neurogastroenterol Motil , vol.14 , pp. 611-623
    • Galligan, J.J.1
  • 68
    • 84874280249 scopus 로고    scopus 로고
    • ATP release and purinergic signaling in NLRP3 inflammasome activation
    • PID: 23316199
    • Gombault A, Baron L, Couillin I (2012) ATP release and purinergic signaling in NLRP3 inflammasome activation. Front Immunol 3:414
    • (2012) Front Immunol , vol.3 , pp. 414
    • Gombault, A.1    Baron, L.2    Couillin, I.3
  • 69
    • 0034531974 scopus 로고    scopus 로고
    • ATP: an extracellular signaling molecule between neurons and glia
    • COI: 1:CAS:528:DC%2BD3MXhsVymsQ%3D%3D, PID: 11137153
    • Fields RD, Stevens B (2000) ATP: an extracellular signaling molecule between neurons and glia. Trends Neurosci 23:625–633
    • (2000) Trends Neurosci , vol.23 , pp. 625-633
    • Fields, R.D.1    Stevens, B.2
  • 70
    • 23244443343 scopus 로고    scopus 로고
    • Glial cells in the gut
    • COI: 1:STN:280:DC%2BD2MnlvVKmug%3D%3D, PID: 16336493
    • Ruhl A (2005) Glial cells in the gut. Neurogastroenterol Motil 17:777–790
    • (2005) Neurogastroenterol Motil , vol.17 , pp. 777-790
    • Ruhl, A.1
  • 71
    • 84951278147 scopus 로고    scopus 로고
    • Enteric glia mediate neuron death in colitis through purinergic pathways that require connexin-43 and nitric oxide
    • PID: 26771001
    • Brown IA, McClain JL, Watson RE, Patel BA, Gulbransen BD (2016) Enteric glia mediate neuron death in colitis through purinergic pathways that require connexin-43 and nitric oxide. Cell Mol Gastroenterol Hepatol 2:77–91
    • (2016) Cell Mol Gastroenterol Hepatol , vol.2 , pp. 77-91
    • Brown, I.A.1    McClain, J.L.2    Watson, R.E.3    Patel, B.A.4    Gulbransen, B.D.5
  • 72
    • 84908492287 scopus 로고    scopus 로고
    • Targeting hypoxia signalling for the treatment of ischaemic and inflammatory diseases
    • COI: 1:CAS:528:DC%2BC2cXhvVCmsrrP, PID: 25359381
    • Eltzschig HK, Bratton DL, Colgan SP (2014) Targeting hypoxia signalling for the treatment of ischaemic and inflammatory diseases. Nat Rev Drug Discov 13:852–869
    • (2014) Nat Rev Drug Discov , vol.13 , pp. 852-869
    • Eltzschig, H.K.1    Bratton, D.L.2    Colgan, S.P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.