메뉴 건너뛰기




Volumn 5, Issue , 2014, Pages

An intestinal commensal symbiosis factor controls neuroinflammation via TLR2-mediated CD39 signalling

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL POLYSACCHARIDE; BACTEROIDES FRAGILIS POLYSACCHARIDE A; CD39 ANTIGEN; IMMUNOMODULATING AGENT; INTERLEUKIN 10; INTERLEUKIN 17; TOLL LIKE RECEPTOR 2; TRANSCRIPTION FACTOR FOXP3; UNCLASSIFIED DRUG; APYRASE; FORKHEAD TRANSCRIPTION FACTOR; FOXP3 PROTEIN, MOUSE; LEUKOCYTE ANTIGEN; TLR2 PROTEIN, MOUSE;

EID: 84904694854     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms5432     Document Type: Article
Times cited : (170)

References (47)
  • 2
    • 74549191082 scopus 로고    scopus 로고
    • The intestinal microbiota in health and disease: The influence of microbial products on immune cell homeostasis
    • Abt, M. C. & Artis, D. The intestinal microbiota in health and disease: the influence of microbial products on immune cell homeostasis. Curr. Opin. Gastroenterol. 25, 496-502 (2009).
    • (2009) Curr. Opin. Gastroenterol. , vol.25 , pp. 496-502
    • Abt, M.C.1    Artis, D.2
  • 4
    • 0036395918 scopus 로고    scopus 로고
    • Understanding immune-microbial homeostasis in intestine
    • Elson, C. O. & Cong, Y. Understanding immune-microbial homeostasis in intestine. Immunol. Res. 26, 87-94 (2002). (Pubitemid 35177487)
    • (2002) Immunologic Research , vol.26 , Issue.1-3 , pp. 87-94
    • Elson, C.O.1    Cong, Y.2
  • 5
    • 67349250428 scopus 로고    scopus 로고
    • The gut microbiota shapes intestinal immune responses during health and disease
    • Round, J. L. & Mazmanian, S. K. The gut microbiota shapes intestinal immune responses during health and disease. Nat. Rev. Immunol. 9, 313-323 (2009).
    • (2009) Nat. Rev. Immunol. , vol.9 , pp. 313-323
    • Round, J.L.1    Mazmanian, S.K.2
  • 6
    • 84862703353 scopus 로고    scopus 로고
    • Commensal gut flora and brain autoimmunity: A love or hate affair?
    • Berer, K. & Krishnamoorthy, G. Commensal gut flora and brain autoimmunity: a love or hate affair? Acta Neuropathol. 123, 639-651 (2012).
    • (2012) Acta Neuropathol , vol.123 , pp. 639-651
    • Berer, K.1    Krishnamoorthy, G.2
  • 7
    • 84862684681 scopus 로고    scopus 로고
    • Intestinal commensals: Influence on immune system and tolerance to pathogens
    • Chervonsky, A. V. Intestinal commensals: influence on immune system and tolerance to pathogens. Curr. Opin. Immunol. 24, 255-260 (2012).
    • (2012) Curr. Opin. Immunol. , vol.24 , pp. 255-260
    • Chervonsky, A.V.1
  • 8
    • 79953160962 scopus 로고    scopus 로고
    • Commensal flora and the regulation of inflammatory and autoimmune responses
    • Kranich, J., Maslowski, K. M. & Mackay, C. R. Commensal flora and the regulation of inflammatory and autoimmune responses. Semin. Immunol. 23, 139-145 (2011).
    • (2011) Semin. Immunol. , vol.23 , pp. 139-145
    • Kranich, J.1    Maslowski, K.M.2    MacKay, C.R.3
  • 9
    • 79952497372 scopus 로고    scopus 로고
    • Gut, bugs, and brain: Role of commensal bacteria in the control of central nervous system disease
    • Ochoa-Reparaz, J., Mielcarz, D. W., Begum-Haque, S. & Kasper, L. H. Gut, bugs, and brain: role of commensal bacteria in the control of central nervous system disease. Ann. Neurol. 69, 240-247 (2011).
    • (2011) Ann. Neurol. , vol.69 , pp. 240-247
    • Ochoa-Reparaz, J.1    Mielcarz, D.W.2    Begum-Haque, S.3    Kasper, L.H.4
  • 10
    • 84898542916 scopus 로고    scopus 로고
    • The role of microbiome in central nervous system disorders
    • Wang, Y. & Kasper, L. H. The role of microbiome in central nervous system disorders. Brain Behav. Immun. 38, 1-12 (2013).
    • (2013) Brain Behav. Immun. , vol.38 , pp. 1-12
    • Wang, Y.1    Kasper, L.H.2
  • 11
    • 84863380407 scopus 로고    scopus 로고
    • The role of gut microbiota in immune homeostasis and autoimmunity
    • Wu, H. J. & Wu, E. The role of gut microbiota in immune homeostasis and autoimmunity. Gut Microbes 3, 4-14 (2012).
    • (2012) Gut Microbes , vol.3 , pp. 4-14
    • Wu, H.J.1    Wu, E.2
  • 12
    • 79952748674 scopus 로고    scopus 로고
    • Proinflammatory T-cell responses to gut microbiota promote experimental autoimmune encephalomyelitis
    • Lee, Y. K., Menezes, J. S., Umesaki, Y. & Mazmanian, S. K. Proinflammatory T-cell responses to gut microbiota promote experimental autoimmune encephalomyelitis. Proc. Natl Acad. Sci. USA 108(Suppl 1): 4615-4622 (2011).
    • (2011) Proc. Natl Acad. Sci. USA , vol.108 , Issue.SUPPL. 1 , pp. 4615-4622
    • Lee, Y.K.1    Menezes, J.S.2    Umesaki, Y.3    Mazmanian, S.K.4
  • 13
    • 77958119730 scopus 로고    scopus 로고
    • Central nervous system demyelinating disease protection by the human commensal Bacteroides fragilis depends on polysaccharide A expression
    • Ochoa-Reparaz, J. et al. Central nervous system demyelinating disease protection by the human commensal Bacteroides fragilis depends on polysaccharide A expression. J. Immunol. 185, 4101-4108 (2010).
    • (2010) J. Immunol. , vol.185 , pp. 4101-4108
    • Ochoa-Reparaz, J.1
  • 14
    • 55449104922 scopus 로고    scopus 로고
    • Effects of bifidobacterium animalis administered during lactation on allergic and autoimmune responses in rodents
    • Ezendam, J., de Klerk, A., Gremmer, E. R. & van Loveren, H. Effects of Bifidobacterium animalis administered during lactation on allergic and autoimmune responses in rodents. Clin. Exp. Immunol. 154, 424-431 (2008).
    • (2008) Clin. Exp. Immunol. , vol.154 , pp. 424-431
    • Ezendam, J.1    De Klerk, A.2    Gremmer, E.R.3    Van Loveren, H.4
  • 15
    • 84873714598 scopus 로고    scopus 로고
    • Amelioration of experimental autoimmune encephalomyelitis by probiotic mixture is mediated by a shift in T helper cell immune response
    • Kwon, H. K. et al. Amelioration of experimental autoimmune encephalomyelitis by probiotic mixture is mediated by a shift in T helper cell immune response. Clin. Immunol. 146, 217-227 (2013).
    • (2013) Clin. Immunol. , vol.146 , pp. 217-227
    • Kwon, H.K.1
  • 16
    • 77749322389 scopus 로고    scopus 로고
    • A novel probiotic mixture exerts a therapeutic effect on experimental autoimmune encephalomyelitis mediated by IL-10 producing regulatory T cells
    • Lavasani, S. et al. A novel probiotic mixture exerts a therapeutic effect on experimental autoimmune encephalomyelitis mediated by IL-10 producing regulatory T cells. PLoS ONE 5, e9009 (2010).
    • (2010) PLoS ONE , vol.5
    • Lavasani, S.1
  • 17
    • 79956311926 scopus 로고    scopus 로고
    • The toll-like receptor 2 pathway establishes colonization by a commensal of the human microbiota
    • Round, J. L. et al. The Toll-like receptor 2 pathway establishes colonization by a commensal of the human microbiota. Science 332, 974-977 (2011).
    • (2011) Science , vol.332 , pp. 974-977
    • Round, J.L.1
  • 18
    • 22144490199 scopus 로고    scopus 로고
    • An immunomodulatory molecule of symbiotic bacteria directs maturation of the host immune system
    • DOI 10.1016/j.cell.2005.05.007, PII S0092867405004514
    • Mazmanian, S. K., Liu, C. H., Tzianabos, A. O. & Kasper, D. L. An immunomodulatory molecule of symbiotic bacteria directs maturation of the host immune system. Cell 122, 107-118 (2005). (Pubitemid 40977944)
    • (2005) Cell , vol.122 , Issue.1 , pp. 107-118
    • Mazmanian, S.K.1    Cui, H.L.2    Tzianabos, A.O.3    Kasper, D.L.4
  • 19
    • 44449106055 scopus 로고    scopus 로고
    • A microbial symbiosis factor prevents intestinal inflammatory disease
    • DOI 10.1038/nature07008, PII NATURE07008
    • Mazmanian, S. K., Round, J. L. & Kasper, D. L. A microbial symbiosis factor prevents intestinal inflammatory disease. Nature 453, 620-625 (2008). (Pubitemid 351769307)
    • (2008) Nature , vol.453 , Issue.7195 , pp. 620-625
    • Mazmanian, S.K.1    Round, J.L.2    Kasper, D.L.3
  • 20
    • 77954738601 scopus 로고    scopus 로고
    • Inducible Foxp3+ regulatory T-cell development by a commensal bacterium of the intestinal microbiota
    • Round, J. L. & Mazmanian, S. K. Inducible Foxp3+ regulatory T-cell development by a commensal bacterium of the intestinal microbiota. Proc. Natl Acad. Sci. USA 107, 12204-12209 (2010).
    • (2010) Proc. Natl Acad. Sci. USA , vol.107 , pp. 12204-12209
    • Round, J.L.1    Mazmanian, S.K.2
  • 21
    • 77955913743 scopus 로고    scopus 로고
    • A polysaccharide from the human commensal Bacteroides fragilis protects against CNS demyelinating disease
    • Ochoa-Reparaz, J. et al. A polysaccharide from the human commensal Bacteroides fragilis protects against CNS demyelinating disease. Mucosal Immunol. 3, 487-495 (2010).
    • (2010) Mucosal Immunol , vol.3 , pp. 487-495
    • Ochoa-Reparaz, J.1
  • 22
    • 70449503002 scopus 로고    scopus 로고
    • Innate receptors and microbes in induction of autoimmunity
    • Chervonsky, A. Innate receptors and microbes in induction of autoimmunity. Curr. Opin. Immunol. 21, 641-647 (2009).
    • (2009) Curr. Opin. Immunol. , vol.21 , pp. 641-647
    • Chervonsky, A.1
  • 23
    • 33750369226 scopus 로고    scopus 로고
    • Toll-like receptors in systemic autoimmune disease
    • DOI 10.1038/nri1957, PII NRI1957
    • Marshak-Rothstein, A. Toll-like receptors in systemic autoimmune disease. Nat. Rev. Immunol. 6, 823-835 (2006). (Pubitemid 44631651)
    • (2006) Nature Reviews Immunology , vol.6 , Issue.11 , pp. 823-835
    • Marshak-Rothstein, A.1
  • 24
    • 84867656021 scopus 로고    scopus 로고
    • Outer membrane vesicles of a human commensal mediate immune regulation and disease protection
    • Shen, Y. et al. Outer membrane vesicles of a human commensal mediate immune regulation and disease protection. Cell Host Microbe 12, 509-520 (2012).
    • (2012) Cell Host Microbe , vol.12 , pp. 509-520
    • Shen, Y.1
  • 25
    • 34548133584 scopus 로고    scopus 로고
    • Multiple sclerosis: A complicated picture of autoimmunity
    • DOI 10.1038/ni1507, PII NI1507
    • McFarland, H. F. & Martin, R. Multiple sclerosis: a complicated picture of autoimmunity. Nat. Immunol. 8, 913-919 (2007). (Pubitemid 47300005)
    • (2007) Nature Immunology , vol.8 , Issue.9 , pp. 913-919
    • McFarland, H.F.1    Martin, R.2
  • 26
    • 35549010987 scopus 로고    scopus 로고
    • The origin and application of experimental autoimmune encephalomyelitis
    • DOI 10.1038/nri2190, PII NRI2190
    • Baxter, A. G. The origin and application of experimental autoimmune encephalomyelitis. Nat. Rev. Immunol. 7, 904-912 (2007). (Pubitemid 350006239)
    • (2007) Nature Reviews Immunology , vol.7 , Issue.11 , pp. 904-912
    • Baxter, A.G.1
  • 27
    • 62849102106 scopus 로고    scopus 로고
    • Surgical excision of CNS-draining lymph nodes reduces relapse severity in chronic-relapsing experimental autoimmune encephalomyelitis
    • van Zwam, M. et al. Surgical excision of CNS-draining lymph nodes reduces relapse severity in chronic-relapsing experimental autoimmune encephalomyelitis. J. Pathol. 217, 543-551 (2009).
    • (2009) J. Pathol. , vol.217 , pp. 543-551
    • Van Zwam, M.1
  • 30
    • 84874644839 scopus 로고    scopus 로고
    • Costimulation blockade: Current perspectives and implications for therapy
    • Kinnear, G., Jones, N. D. & Wood, K. J. Costimulation blockade: current perspectives and implications for therapy. Transplantation 95, 527-535 (2013).
    • (2013) Transplantation , vol.95 , pp. 527-535
    • Kinnear, G.1    Jones, N.D.2    Wood, K.J.3
  • 32
    • 0026681864 scopus 로고
    • Characterization of the lymphocyte activation gene 3-encoded protein. A new ligand for human leukocyte antigen class II antigens
    • Baixeras, E. et al. Characterization of the lymphocyte activation gene 3-encoded protein. A new ligand for human leukocyte antigen class II antigens. J. Exp. Med. 176, 327-337 (1992).
    • (1992) J. Exp. Med. , vol.176 , pp. 327-337
    • Baixeras, E.1
  • 33
    • 79952717517 scopus 로고    scopus 로고
    • VISTA, a novel mouse Ig superfamily ligand that negatively regulates T cell responses
    • Wang, L. et al. VISTA, a novel mouse Ig superfamily ligand that negatively regulates T cell responses. J. Exp. Med. 208, 577-592 (2011).
    • (2011) J. Exp. Med. , vol.208 , pp. 577-592
    • Wang, L.1
  • 34
    • 84875663346 scopus 로고    scopus 로고
    • Co-stimulation through 4-1BB/CD137 improves the expansion and function of CD8(+) melanoma tumor-infiltrating lymphocytes for adoptive T-cell therapy
    • Chacon, J. A. et al. Co-stimulation through 4-1BB/CD137 improves the expansion and function of CD8(+) melanoma tumor-infiltrating lymphocytes for adoptive T-cell therapy. PLoS ONE 8, e60031 (2013).
    • (2013) PLoS ONE , vol.8
    • Chacon, J.A.1
  • 37
    • 0036791004 scopus 로고    scopus 로고
    • Expression of the integrin alpha Ebeta 7 identifies unique subsets of CD25+ as well as CD25-regulatory T cells
    • Lehmann, J. et al. Expression of the integrin alpha Ebeta 7 identifies unique subsets of CD25+ as well as CD25-regulatory T cells. Proc. Natl Acad. Sci. USA 99, 13031-13036 (2002).
    • (2002) Proc. Natl Acad. Sci. USA , vol.99 , pp. 13031-13036
    • Lehmann, J.1
  • 38
    • 65449124271 scopus 로고    scopus 로고
    • Regulatory mechanisms of immune responses to intestinal bacteria
    • Honda, K. & Takeda, K. Regulatory mechanisms of immune responses to intestinal bacteria. Mucosal Immunol. 2, 187-196 (2009).
    • (2009) Mucosal Immunol , vol.2 , pp. 187-196
    • Honda, K.1    Takeda, K.2
  • 39
    • 81555201125 scopus 로고    scopus 로고
    • Immune responses to gut microbiotacommensals and pathogens
    • Tanoue, T., Umesaki, Y. & Honda, K. Immune responses to gut microbiotacommensals and pathogens. Gut Microbes 1, 224-233 (2010).
    • (2010) Gut Microbes , vol.1 , pp. 224-233
    • Tanoue, T.1    Umesaki, Y.2    Honda, K.3
  • 41
    • 77249096486 scopus 로고    scopus 로고
    • Role of gut commensal microflora in the development of experimental autoimmune encephalomyelitis
    • Ochoa-Reparaz, J. et al. Role of gut commensal microflora in the development of experimental autoimmune encephalomyelitis. J. Immunol. 183, 6041-6050 (2009).
    • (2009) J. Immunol. , vol.183 , pp. 6041-6050
    • Ochoa-Reparaz, J.1
  • 42
    • 81855167104 scopus 로고    scopus 로고
    • Commensal microbiota and myelin autoantigen cooperate to trigger autoimmune demyelination
    • Berer, K. et al. Commensal microbiota and myelin autoantigen cooperate to trigger autoimmune demyelination. Nature 479, 538-541 (2011).
    • (2011) Nature , vol.479 , pp. 538-541
    • Berer, K.1
  • 43
    • 33846436678 scopus 로고    scopus 로고
    • The E-NTPDase family of ectonucleotidases: Structure function relationships and pathophysiological significance
    • Robson, S. C., Sevigny, J. & Zimmermann, H. The E-NTPDase family of ectonucleotidases: Structure function relationships and pathophysiological significance. Purinergic Signal. 2, 409-430 (2006).
    • (2006) Purinergic Signal , vol.2 , pp. 409-430
    • Robson, S.C.1    Sevigny, J.2    Zimmermann, H.3
  • 44
    • 53649100675 scopus 로고    scopus 로고
    • ATP drives lamina propria T(H)17 cell differentiation
    • Atarashi, K. et al. ATP drives lamina propria T(H)17 cell differentiation. Nature 455, 808-812 (2008).
    • (2008) Nature , vol.455 , pp. 808-812
    • Atarashi, K.1
  • 45
    • 73349127157 scopus 로고    scopus 로고
    • CD39+Foxp3+ regulatory T Cells suppress pathogenic Th17 cells and are impaired in multiple sclerosis
    • Fletcher, J. M. et al. CD39+Foxp3+ regulatory T Cells suppress pathogenic Th17 cells and are impaired in multiple sclerosis. J. Immunol. 183, 7602-7610 (2009).
    • (2009) J. Immunol. , vol.183 , pp. 7602-7610
    • Fletcher, J.M.1
  • 46
    • 77953627758 scopus 로고    scopus 로고
    • IL-35 stimulation of CD39+ regulatory T cells confers protection against collagen II-induced arthritis via the production of IL-10
    • Kochetkova, I., Golden, S., Holderness, K., Callis, G. & Pascual, D. W. IL-35 stimulation of CD39+ regulatory T cells confers protection against collagen II-induced arthritis via the production of IL-10. J. Immunol. 184, 7144-7153 (2010).
    • (2010) J. Immunol. , vol.184 , pp. 7144-7153
    • Kochetkova, I.1    Golden, S.2    Holderness, K.3    Callis, G.4    Pascual, D.W.5
  • 47
    • 80555154833 scopus 로고    scopus 로고
    • Segregated regulatory CD39+CD4+ T cell function: TGF-beta-producing Foxp3- and IL-10-producing Foxp3+ cells are interdependent for protection against collagen-induced arthritis
    • Kochetkova, I., Thornburg, T., Callis, G. & Pascual, D. W. Segregated regulatory CD39+CD4+ T cell function: TGF-beta-producing Foxp3- and IL-10-producing Foxp3+ cells are interdependent for protection against collagen-induced arthritis. J. Immunol. 187, 4654-4666 (2011).
    • (2011) J. Immunol. , vol.187 , pp. 4654-4666
    • Kochetkova, I.1    Thornburg, T.2    Callis, G.3    Pascual, D.W.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.