메뉴 건너뛰기




Volumn 15, Issue 1, 2015, Pages

A 3D-microtissue-based phenotypic screening of radiation resistant tumor cells with synchronized chemotherapeutic treatment

Author keywords

3D microtissues; High content screen (HCS); Potentiating drugs; Radiation therapy; Tumor growth; Vinblastine

Indexed keywords

DOCETAXEL; DOXORUBICIN; VINBLASTINE; TAXOID;

EID: 85019238702     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/s12885-015-1481-9     Document Type: Article
Times cited : (48)

References (40)
  • 1
    • 80053587355 scopus 로고    scopus 로고
    • Effects of phytochemicals on ionization radiation-mediated carcinogenesis and cancer therapy
    • Nambiar D, Rajamani P, Singh RP. Effects of phytochemicals on ionization radiation-mediated carcinogenesis and cancer therapy. Mutat Res. 2011;728(3):139-57.
    • (2011) Mutat Res , vol.728 , Issue.3 , pp. 139-157
    • Nambiar, D.1    Rajamani, P.2    Singh, R.P.3
  • 2
    • 79953054421 scopus 로고    scopus 로고
    • Strategies to improve radiotherapy with targeted drugs
    • Begg AC, Stewart FA, Vens C. Strategies to improve radiotherapy with targeted drugs. Nat Rev Cancer. 2011;11(4):239-53.
    • (2011) Nat Rev Cancer , vol.11 , Issue.4 , pp. 239-253
    • Begg, A.C.1    Stewart, F.A.2    Vens, C.3
  • 3
    • 77949957365 scopus 로고    scopus 로고
    • Cell line-based platforms to evaluate the therapeutic efficacy of candidate anticancer agents
    • Sharma SV, Haber DA, Settleman J. Cell line-based platforms to evaluate the therapeutic efficacy of candidate anticancer agents. Nat Rev Cancer. 2010;10(4):241-53.
    • (2010) Nat Rev Cancer , vol.10 , Issue.4 , pp. 241-253
    • Sharma, S.V.1    Haber, D.A.2    Settleman, J.3
  • 4
    • 81355127248 scopus 로고    scopus 로고
    • Modeling cellular processes in 3D
    • Mogilner A, Odde D. Modeling cellular processes in 3D. Trends Cell Biol. 2011;21(12):692-700.
    • (2011) Trends Cell Biol , vol.21 , Issue.12 , pp. 692-700
    • Mogilner, A.1    Odde, D.2
  • 5
    • 84905496728 scopus 로고    scopus 로고
    • Phenotypic screening in cancer drug discovery - past, present and future
    • Moffat JG, Rudolph J, Bailey D. Phenotypic screening in cancer drug discovery - past, present and future. Nat Rev Drug Discov. 2014;13(8):588-602.
    • (2014) Nat Rev Drug Discov , vol.13 , Issue.8 , pp. 588-602
    • Moffat, J.G.1    Rudolph, J.2    Bailey, D.3
  • 6
    • 84873291429 scopus 로고    scopus 로고
    • Development, validation and pilot screening of an in vitro multi-cellular three-dimensional cancer spheroid assay for anti-cancer drug testing
    • Lama R, Zhang L, Naim JM, Williams J, Zhou A, Su B. Development, validation and pilot screening of an in vitro multi-cellular three-dimensional cancer spheroid assay for anti-cancer drug testing. Bioorg Med Chem. 2013;21(4):922-31.
    • (2013) Bioorg Med Chem , vol.21 , Issue.4 , pp. 922-931
    • Lama, R.1    Zhang, L.2    Naim, J.M.3    Williams, J.4    Zhou, A.5    Su, B.6
  • 7
    • 0018145854 scopus 로고
    • In vitro analysis of the response of multicellular tumor spheroids exposed to chemotherapeutic agents in vitro or in vivo
    • Yuhas JM, Tarleton AE, Harman JG. In vitro analysis of the response of multicellular tumor spheroids exposed to chemotherapeutic agents in vitro or in vivo. Cancer Res. 1978;38(11 Pt 1):3595-8.
    • (1978) Cancer Res , vol.38 , Issue.11 , pp. 3595-3598
    • Yuhas, J.M.1    Tarleton, A.E.2    Harman, J.G.3
  • 8
    • 0021671188 scopus 로고
    • Quantitation of the response of human tumor spheroids to daily radiation exposures
    • Yuhas JM, Blake S, Weichselbaum RR. Quantitation of the response of human tumor spheroids to daily radiation exposures. Int J Radiat Oncol Biol Phys. 1984;10(12):2323-7.
    • (1984) Int J Radiat Oncol Biol Phys , vol.10 , Issue.12 , pp. 2323-2327
    • Yuhas, J.M.1    Blake, S.2    Weichselbaum, R.R.3
  • 9
    • 78449290991 scopus 로고    scopus 로고
    • Incorporation of multicellular spheroids into 3-D polymeric scaffolds provides an improved tumor model for screening anticancer drugs
    • Ho WJ, Pham EA, Kim JW, Ng CW, Kim JH, Kamei DT, et al. Incorporation of multicellular spheroids into 3-D polymeric scaffolds provides an improved tumor model for screening anticancer drugs. Cancer Sci. 2010;101(12):2637-43.
    • (2010) Cancer Sci , vol.101 , Issue.12 , pp. 2637-2643
    • Ho, W.J.1    Pham, E.A.2    Kim, J.W.3    Ng, C.W.4    Kim, J.H.5    Kamei, D.T.6
  • 10
    • 60549103259 scopus 로고    scopus 로고
    • Spheroid-based drug screen: considerations and practical approach
    • Friedrich J, Seidel C, Ebner R, Kunz-Schughart LA. Spheroid-based drug screen: considerations and practical approach. Nat Protoc. 2009;4(3):309-24.
    • (2009) Nat Protoc , vol.4 , Issue.3 , pp. 309-324
    • Friedrich, J.1    Seidel, C.2    Ebner, R.3    Kunz-Schughart, L.A.4
  • 11
    • 84858448828 scopus 로고    scopus 로고
    • 384 hanging drop arrays give excellent Z-factors and allow versatile formation of co-culture spheroids
    • Hsiao AY, Tung YC, Qu X, Patel LR, Pienta KJ, Takayama S. 384 hanging drop arrays give excellent Z-factors and allow versatile formation of co-culture spheroids. Biotechnol Bioeng. 2012;109(5):1293-304.
    • (2012) Biotechnol Bioeng , vol.109 , Issue.5 , pp. 1293-1304
    • Hsiao, A.Y.1    Tung, Y.C.2    Qu, X.3    Patel, L.R.4    Pienta, K.J.5    Takayama, S.6
  • 12
    • 83455236148 scopus 로고    scopus 로고
    • Towards automated production and drug sensitivity testing using scaffold-free spherical tumor microtissues
    • Drewitz M, Helbling M, Fried N, Bieri M, Moritz W, Lichtenberg J, et al. Towards automated production and drug sensitivity testing using scaffold-free spherical tumor microtissues. Biotechnol J. 2011;6(12):1488-96.
    • (2011) Biotechnol J , vol.6 , Issue.12 , pp. 1488-1496
    • Drewitz, M.1    Helbling, M.2    Fried, N.3    Bieri, M.4    Moritz, W.5    Lichtenberg, J.6
  • 13
    • 84867139870 scopus 로고    scopus 로고
    • Effect of homotypic and heterotypic interaction in 3D on the E-selectin mediated adhesive properties of breast cancer cell lines
    • Chandrasekaran S, Geng Y, DeLouise LA, King MR. Effect of homotypic and heterotypic interaction in 3D on the E-selectin mediated adhesive properties of breast cancer cell lines. Biomaterials. 2012;33(35):9037-48.
    • (2012) Biomaterials , vol.33 , Issue.35 , pp. 9037-9048
    • Chandrasekaran, S.1    Geng, Y.2    DeLouise, L.A.3    King, M.R.4
  • 14
    • 84899966772 scopus 로고    scopus 로고
    • The need for complex 3D culture models to unravel novel pathways and identify accurate biomarkers in breast cancer
    • Weigelt B, Bissell MJ. The need for complex 3D culture models to unravel novel pathways and identify accurate biomarkers in breast cancer. Adv Drug Deliv Rev. 2014;69-70:42-51.
    • (2014) Adv Drug Deliv Rev , vol.69-70 , pp. 42-51
    • Weigelt, B.1    Bissell, M.J.2
  • 15
    • 84899945356 scopus 로고    scopus 로고
    • 3D cell culture systems modeling tumor growth determinants in cancer target discovery
    • Thoma CR, Zimmermann M, Agarkova I, Kelm JM, Krek W. 3D cell culture systems modeling tumor growth determinants in cancer target discovery. Adv Drug Deliv Rev. 2014;69-70:29-41.
    • (2014) Adv Drug Deliv Rev , vol.69-70 , pp. 29-41
    • Thoma, C.R.1    Zimmermann, M.2    Agarkova, I.3    Kelm, J.M.4    Krek, W.5
  • 16
    • 77952300119 scopus 로고    scopus 로고
    • Efficient shRNA delivery into B and T lymphoma cells using lentiviral vector-mediated transfer
    • Anastasov N, Klier M, Koch I, Angermeier D, Hofler H, Fend F, et al. Efficient shRNA delivery into B and T lymphoma cells using lentiviral vector-mediated transfer. J Hematop. 2009;2(1):9-19.
    • (2009) J Hematop , vol.2 , Issue.1 , pp. 9-19
    • Anastasov, N.1    Klier, M.2    Koch, I.3    Angermeier, D.4    Hofler, H.5    Fend, F.6
  • 17
    • 84870384133 scopus 로고    scopus 로고
    • Radiation resistance due to high expression of miR-21 and G2/M checkpoint arrest in breast cancer cells
    • Anastasov N, Hofig I, Vasconcellos IG, Rappl K, Braselmann H, Ludyga N, et al. Radiation resistance due to high expression of miR-21 and G2/M checkpoint arrest in breast cancer cells. Radiat Oncol. 2012;7:206.
    • (2012) Radiat Oncol , vol.7 , pp. 206
    • Anastasov, N.1    Hofig, I.2    Vasconcellos, I.G.3    Rappl, K.4    Braselmann, H.5    Ludyga, N.6
  • 18
    • 77952310507 scopus 로고    scopus 로고
    • C/EBPbeta expression in ALK-positive anaplastic large cell lymphomas is required for cell proliferation and is induced by the STAT3 signaling pathway
    • Anastasov N, Bonzheim I, Rudelius M, Klier M, Dau T, Angermeier D, et al. C/EBPbeta expression in ALK-positive anaplastic large cell lymphomas is required for cell proliferation and is induced by the STAT3 signaling pathway. Haematologica. 2010;95(5):760-7.
    • (2010) Haematologica , vol.95 , Issue.5 , pp. 760-767
    • Anastasov, N.1    Bonzheim, I.2    Rudelius, M.3    Klier, M.4    Dau, T.5    Angermeier, D.6
  • 20
    • 84896739248 scopus 로고    scopus 로고
    • Systematic improvement of lentivirus transduction protocols by antibody fragments fused to VSV-G as envelope glycoprotein
    • Hofig I, Barth S, Salomon M, Jagusch V, Atkinson MJ, Anastasov N, et al. Systematic improvement of lentivirus transduction protocols by antibody fragments fused to VSV-G as envelope glycoprotein. Biomaterials. 2014;35(13):4204-12.
    • (2014) Biomaterials , vol.35 , Issue.13 , pp. 4204-4212
    • Hofig, I.1    Barth, S.2    Salomon, M.3    Jagusch, V.4    Atkinson, M.J.5    Anastasov, N.6
  • 22
    • 34548268026 scopus 로고    scopus 로고
    • Modelling breast cancer: one size does not fit all
    • Vargo-Gogola T, Rosen JM. Modelling breast cancer: one size does not fit all. Nat Rev Cancer. 2007;7(9):659-72.
    • (2007) Nat Rev Cancer , vol.7 , Issue.9 , pp. 659-672
    • Vargo-Gogola, T.1    Rosen, J.M.2
  • 24
    • 0030000299 scopus 로고    scopus 로고
    • Interaction of ionizing radiation with paclitaxel (Taxol) and docetaxel (Taxotere) in HeLa and SQ20B cells
    • Hennequin C, Giocanti N, Favaudon V. Interaction of ionizing radiation with paclitaxel (Taxol) and docetaxel (Taxotere) in HeLa and SQ20B cells. Cancer Res. 1996;56(8):1842-50.
    • (1996) Cancer Res , vol.56 , Issue.8 , pp. 1842-1850
    • Hennequin, C.1    Giocanti, N.2    Favaudon, V.3
  • 25
    • 0028242306 scopus 로고
    • Enhancement of tumor radioresponse of a murine mammary carcinoma by paclitaxel
    • Milas L, Hunter NR, Mason KA, Kurdoglu B, Peters LJ. Enhancement of tumor radioresponse of a murine mammary carcinoma by paclitaxel. Cancer Res. 1994;54(13):3506-10.
    • (1994) Cancer Res , vol.54 , Issue.13 , pp. 3506-3510
    • Milas, L.1    Hunter, N.R.2    Mason, K.A.3    Kurdoglu, B.4    Peters, L.J.5
  • 26
    • 3242717580 scopus 로고    scopus 로고
    • Cell cycle-dependent antagonistic interactions between paclitaxel and gamma-radiation in combination therapy
    • Sui M, Dziadyk JM, Zhu X, Fan W. Cell cycle-dependent antagonistic interactions between paclitaxel and gamma-radiation in combination therapy. Clin Cancer Res. 2004;10(14):4848-57.
    • (2004) Clin Cancer Res , vol.10 , Issue.14 , pp. 4848-4857
    • Sui, M.1    Dziadyk, J.M.2    Zhu, X.3    Fan, W.4
  • 27
    • 14844323112 scopus 로고    scopus 로고
    • Combination of gamma-radiation antagonizes the cytotoxic effects of vincristine and vinblastine on both mitotic arrest and apoptosis
    • Sui M, Fan W. Combination of gamma-radiation antagonizes the cytotoxic effects of vincristine and vinblastine on both mitotic arrest and apoptosis. Int J Radiat Oncol Biol Phys. 2005;61(4):1151-8.
    • (2005) Int J Radiat Oncol Biol Phys , vol.61 , Issue.4 , pp. 1151-1158
    • Sui, M.1    Fan, W.2
  • 28
    • 84902533633 scopus 로고    scopus 로고
    • A high content clonogenic survival drug screen identifies mek inhibitors as potent radiation sensitizers for KRAS mutant non-small-cell lung cancer
    • Lin SH, Zhang J, Giri U, Stephan C, Sobieski M, Zhong L, et al. A high content clonogenic survival drug screen identifies mek inhibitors as potent radiation sensitizers for KRAS mutant non-small-cell lung cancer. J Thorac Oncol. 2014;9(7):965-73.
    • (2014) J Thorac Oncol , vol.9 , Issue.7 , pp. 965-973
    • Lin, S.H.1    Zhang, J.2    Giri, U.3    Stephan, C.4    Sobieski, M.5    Zhong, L.6
  • 29
    • 84858723379 scopus 로고    scopus 로고
    • Advances in establishment and analysis of three-dimensional tumor spheroid-based functional assays for target validation and drug evaluation
    • Vinci M, Gowan S, Boxall F, Patterson L, Zimmermann M, Court W, et al. Advances in establishment and analysis of three-dimensional tumor spheroid-based functional assays for target validation and drug evaluation. BMC Biol. 2012;10:29.
    • (2012) BMC Biol , vol.10 , pp. 29
    • Vinci, M.1    Gowan, S.2    Boxall, F.3    Patterson, L.4    Zimmermann, M.5    Court, W.6
  • 30
    • 79952000716 scopus 로고    scopus 로고
    • 3D models of epithelial-mesenchymal transition in breast cancer metastasis: high-throughput screening assay development, validation, and pilot screen
    • Li Q, Chen C, Kapadia A, Zhou Q, Harper MK, Schaack J, et al. 3D models of epithelial-mesenchymal transition in breast cancer metastasis: high-throughput screening assay development, validation, and pilot screen. J Biomol Screen. 2011;16(2):141-54.
    • (2011) J Biomol Screen , vol.16 , Issue.2 , pp. 141-154
    • Li, Q.1    Chen, C.2    Kapadia, A.3    Zhou, Q.4    Harper, M.K.5    Schaack, J.6
  • 31
    • 78149357610 scopus 로고    scopus 로고
    • Adjuvant chemotherapy prior to postoperative concurrent chemoradiotherapy for locoregionally advanced head and neck cancer
    • Choe KS, Salama JK, Stenson KM, Blair EA, Witt ME, Cohen EE, et al. Adjuvant chemotherapy prior to postoperative concurrent chemoradiotherapy for locoregionally advanced head and neck cancer. Radiother Oncol. 2010;97(2):318-21.
    • (2010) Radiother Oncol , vol.97 , Issue.2 , pp. 318-321
    • Choe, K.S.1    Salama, J.K.2    Stenson, K.M.3    Blair, E.A.4    Witt, M.E.5    Cohen, E.E.6
  • 32
    • 84865800234 scopus 로고    scopus 로고
    • G2 checkpoint abrogator abates the antagonistic interaction between antimicrotubule drugs and radiation therapy
    • Sui M, Zhang H, Di X, Chang J, Shen Y, Fan W. G2 checkpoint abrogator abates the antagonistic interaction between antimicrotubule drugs and radiation therapy. Radiother Oncol. 2012;104(2):243-8.
    • (2012) Radiother Oncol , vol.104 , Issue.2 , pp. 243-248
    • Sui, M.1    Zhang, H.2    Di, X.3    Chang, J.4    Shen, Y.5    Fan, W.6
  • 33
    • 0042709556 scopus 로고    scopus 로고
    • Docetaxel-based combined-modality chemoradiotherapy for locally advanced non-small cell lung cancer
    • Scagliotti GV, Turrisi 3rd AT. Docetaxel-based combined-modality chemoradiotherapy for locally advanced non-small cell lung cancer. Oncologist. 2003;8(4):361-74.
    • (2003) Oncologist , vol.8 , Issue.4 , pp. 361-374
    • Scagliotti, G.V.1    Turrisi, A.T.2
  • 34
    • 0037445247 scopus 로고    scopus 로고
    • Docetaxel and doxorubicin compared with doxorubicin and cyclophosphamide as first-line chemotherapy for metastatic breast cancer: results of a randomized, multicenter, phase III trial
    • Nabholtz JM, Falkson C, Campos D, Szanto J, Martin M, Chan S, et al. Docetaxel and doxorubicin compared with doxorubicin and cyclophosphamide as first-line chemotherapy for metastatic breast cancer: results of a randomized, multicenter, phase III trial. J Clin Oncol. 2003;21(6):968-75.
    • (2003) J Clin Oncol , vol.21 , Issue.6 , pp. 968-975
    • Nabholtz, J.M.1    Falkson, C.2    Campos, D.3    Szanto, J.4    Martin, M.5    Chan, S.6
  • 35
    • 84872046445 scopus 로고    scopus 로고
    • A modified Phase I trial of radiation dose escalation in 3D conformal radiation therapy with concurrent vinorelbine and carboplatin chemotherapy for non-small-cell lung cancer
    • Lin Q, Liu Y, Wang N, Huang Y, Ge X, Ren X, et al. A modified Phase I trial of radiation dose escalation in 3D conformal radiation therapy with concurrent vinorelbine and carboplatin chemotherapy for non-small-cell lung cancer. J Radiat Res. 2013;54(1):126-34.
    • (2013) J Radiat Res , vol.54 , Issue.1 , pp. 126-134
    • Lin, Q.1    Liu, Y.2    Wang, N.3    Huang, Y.4    Ge, X.5    Ren, X.6
  • 37
    • 0034908632 scopus 로고    scopus 로고
    • Phase I dose-finding and pharmacokinetic study of docetaxel and vinorelbine as first-line chemotherapy for metastatic breast cancer
    • Campone M, Fumoleau P, Delecroix V, Deporte-Fety R, Perrocheau G, Vernillet L, et al. Phase I dose-finding and pharmacokinetic study of docetaxel and vinorelbine as first-line chemotherapy for metastatic breast cancer. Ann Oncol. 2001;12(7):909-18.
    • (2001) Ann Oncol , vol.12 , Issue.7 , pp. 909-918
    • Campone, M.1    Fumoleau, P.2    Delecroix, V.3    Deporte-Fety, R.4    Perrocheau, G.5    Vernillet, L.6
  • 38
    • 0034948795 scopus 로고    scopus 로고
    • Interaction between novel anticancer agents and radiation in non-small cell lung cancer cell lines
    • Loprevite M, Favoni RE, de Cupis A, Pirani P, Pietra G, Bruno S, et al. Interaction between novel anticancer agents and radiation in non-small cell lung cancer cell lines. Lung Cancer. 2001;33(1):27-39.
    • (2001) Lung Cancer , vol.33 , Issue.1 , pp. 27-39
    • Loprevite, M.1    Favoni, R.E.2    Cupis, A.3    Pirani, P.4    Pietra, G.5    Bruno, S.6
  • 39
    • 0029113685 scopus 로고
    • Effect of paclitaxel (taxol) alone and in combination with radiation on the gastrointestinal mucosa
    • Mason KA, Milas L, Peters LJ. Effect of paclitaxel (taxol) alone and in combination with radiation on the gastrointestinal mucosa. Int J Radiat Oncol Biol Phys. 1995;32(5):1381-9.
    • (1995) Int J Radiat Oncol Biol Phys , vol.32 , Issue.5 , pp. 1381-1389
    • Mason, K.A.1    Milas, L.2    Peters, L.J.3
  • 40
    • 0037441856 scopus 로고    scopus 로고
    • Phase III trial of doxorubicin, paclitaxel, and the combination of doxorubicin and paclitaxel as front-line chemotherapy for metastatic breast cancer: an intergroup trial (E1193)
    • Sledge GW, Neuberg D, Bernardo P, Ingle JN, Martino S, Rowinsky EK, et al. Phase III trial of doxorubicin, paclitaxel, and the combination of doxorubicin and paclitaxel as front-line chemotherapy for metastatic breast cancer: an intergroup trial (E1193). J Clin Oncol. 2003;21(4):588-92.
    • (2003) J Clin Oncol , vol.21 , Issue.4 , pp. 588-592
    • Sledge, G.W.1    Neuberg, D.2    Bernardo, P.3    Ingle, J.N.4    Martino, S.5    Rowinsky, E.K.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.