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Volumn 6, Issue 1, 2017, Pages 15-20

Role of inflammatory cytokines in depression: Focus on interleukin-1β (Review)

Author keywords

Cytokines; Depression; Interleukin 1 ; Neuroinflammation

Indexed keywords

AMINE; ANTIDEPRESSANT AGENT; CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 1BETA; MITOGEN ACTIVATED PROTEIN KINASE; PURINERGIC P2X7 RECEPTOR; SEROTONIN; TUMOR NECROSIS FACTOR;

EID: 85019174065     PISSN: 20499434     EISSN: 20499442     Source Type: Journal    
DOI: 10.3892/br.2016.807     Document Type: Review
Times cited : (116)

References (83)
  • 1
    • 33845338724 scopus 로고    scopus 로고
    • Projections of global mortality and burden of disease from 2002 to 2030
    • Mathers CD and Loncar D: Projections of global mortality and burden of disease from 2002 to 2030. PLoS Med 3: e442, 2006.
    • (2006) Plos Med , pp. 3
    • Mathers, C.D.1    Loncar, D.2
  • 2
    • 84930857290 scopus 로고    scopus 로고
    • Positive psychology: An introduction. Springer Netherlands
    • Seligman ME and Csikszentmihalyi M: Positive psychology: an introduction. Springer Netherlands, Dordrecht, pp279-298, 2014.
    • (2014) Dordrecht , pp. 279-298
    • Seligman, M.E.1    Csikszentmihalyi, M.2
  • 3
    • 0020695378 scopus 로고
    • Clinical and laboratory studies with selective monoamine-oxidase-inhibiting drugs. Implications for hypothesized neurotransmitter changes associated with depression and antidepressant drug effects
    • Murphy DL, Cohen RM, Siever LJ, Roy B, Karoum F, Wyatt RJ, Garrick NA and Linnoila M: Clinical and laboratory studies with selective monoamine-oxidase-inhibiting drugs. Implications for hypothesized neurotransmitter changes associated with depression and antidepressant drug effects. Mod Probl Pharmacopsychiatry 19: 287-303, 1983.
    • (1983) Mod Probl Pharmacopsychiatry , vol.19 , pp. 287-303
    • Murphy, D.L.1    Cohen, R.M.2    Siever, L.J.3    Roy, B.4    Karoum, F.5    Wyatt, R.J.6    Garrick, N.A.7    Linnoila, M.8
  • 4
    • 0002854148 scopus 로고
    • High time for psychoimmunology
    • Ader R and Cohen N: High time for psychoimmunology. Nature 315: 103-104, 1985.
    • (1985) Nature , vol.315 , pp. 103-104
    • Ader, R.1    Cohen, N.2
  • 5
    • 0028796205 scopus 로고
    • Evidence for an immune response in major depression: A review and hypothesis
    • Maes M: Evidence for an immune response in major depression: A review and hypothesis. Prog Neuropsychopharmacol Biol Psychiatry 19: 11-38, 1995.
    • (1995) Prog Neuropsychopharmacol Biol Psychiatry , vol.19 , pp. 11-38
    • Maes, M.1
  • 6
    • 84862993854 scopus 로고    scopus 로고
    • Depression and sickness behavior are Janus-faced responses to shared inflammatory pathways
    • Maes M, Berk M, Goehler L, Song C, Anderson G, Gałecki P and Leonard B: Depression and sickness behavior are Janus-faced responses to shared inflammatory pathways. BMC Med 10: 66, 2012.
    • (2012) BMC Med , vol.10 , pp. 66
    • Maes, M.1    Berk, M.2    Goehler, L.3    Song, C.4    Erson, G.5    Gałecki, P.6    Leonard, B.7
  • 7
    • 84924191380 scopus 로고    scopus 로고
    • Neuroinflammation, microglia and mast cells in the pathophysiology of neurocognitive disorders: A review
    • Skaper SD, Facci L and Giusti P: Neuroinflammation, microglia and mast cells in the pathophysiology of neurocognitive disorders: a review. CNS Neurol Disord Drug Targets 13: 1654-1666, 2014.
    • (2014) CNS Neurol Disord Drug Targets , vol.13 , pp. 1654-1666
    • Skaper, S.D.1    Facci, L.2    Giusti, P.3
  • 8
    • 0030576911 scopus 로고    scopus 로고
    • Alterations in iron metabolism and the erythron in major depression: Further evidence for a chronic inflammatory process
    • Maes M, Van de Vyvere J, Vandoolaeghe E, Bril T, Demedts P, Wauters A and Neels H: Alterations in iron metabolism and the erythron in major depression: Further evidence for a chronic inflammatory process. J Affect Disord 40: 23-33, 1996.
    • (1996) J Affect Disord , vol.40 , pp. 23-33
    • Maes, M.1    van De Vyvere, J.2    Vandoolaeghe, E.3    Bril, T.4    Demedts, P.5    Wauters, A.6    Neels, H.7
  • 9
    • 0025910497 scopus 로고
    • The macrophage theory of depression
    • Smith RS: The macrophage theory of depression. Med Hypotheses 35: 298-306, 1991.
    • (1991) Med Hypotheses , vol.35 , pp. 298-306
    • Smith, R.S.1
  • 10
    • 84892415880 scopus 로고    scopus 로고
    • Review: The role of inflammation in depression
    • Patel A: Review: The role of inflammation in depression. Psychiatr Danub 25 (Suppl 2): S216-S223, 2013.
    • (2013) Psychiatr Danub , vol.25 , pp. S216-S223
    • Patel, A.1
  • 11
    • 64649092338 scopus 로고    scopus 로고
    • Cytokine, sickness behavior, and depression
    • Dantzer R: Cytokine, sickness behavior, and depression. Immunol Allergy Clin North Am 29: 247-264, 2009.
    • (2009) Immunol Allergy Clin North Am , vol.29 , pp. 247-264
    • Dantzer, R.1
  • 12
    • 0024159821 scopus 로고
    • Biological basis of the behavior of sick animals
    • Hart BL: Biological basis of the behavior of sick animals. Neurosci Biobehav Rev 12: 123-137, 1988.
    • (1988) Neurosci Biobehav Rev , vol.12 , pp. 123-137
    • Hart, B.L.1
  • 14
    • 30544445602 scopus 로고    scopus 로고
    • Cytokines sing the blues: Inflammation and the pathogenesis of depression
    • Raison CL, Capuron L and Miller AH: Cytokines sing the blues: Inflammation and the pathogenesis of depression. Trends Immunol 27: 24-31, 2006.
    • (2006) Trends Immunol , vol.27 , pp. 24-31
    • Raison, C.L.1    Capuron, L.2    Miller, A.H.3
  • 15
    • 0033281988 scopus 로고    scopus 로고
    • Immune correlates of depression
    • Irwin M: Immune correlates of depression. Adv Exp Med Biol 461: 1-24, 1999.
    • (1999) Adv Exp Med Biol , vol.461 , pp. 1-24
    • Irwin, M.1
  • 16
    • 27744596086 scopus 로고    scopus 로고
    • Association of resolution of major depression with increased natural killer cell activity among HIV-seropositive women
    • Cruess DG, Douglas SD, Petitto JM, Have TT, Gettes D, Dubé B, Cary M and Evans DL: Association of resolution of major depression with increased natural killer cell activity among HIV-seropositive women. Am J Psychiatry 162: 2125-2130, 2005.
    • (2005) Am J Psychiatry , vol.162 , pp. 2125-2130
    • Cruess, D.G.1    Douglas, S.D.2    Petitto, J.M.3    Have, T.T.4    Gettes, D.5    Dubé, B.6    Cary, M.7    Evans, D.L.8
  • 18
    • 32044434659 scopus 로고    scopus 로고
    • Dissociation of inflammatory markers and natural killer cell activity in major depressive disorder
    • Pike JL and Irwin MR: Dissociation of inflammatory markers and natural killer cell activity in major depressive disorder. Brain Behav Immun 20: 169-174, 2006.
    • (2006) Brain Behav Immun , vol.20 , pp. 169-174
    • Pike, J.L.1    Irwin, M.R.2
  • 20
    • 84862125217 scopus 로고    scopus 로고
    • Interleukin (IL)-6, tumour necrosis factor alpha (TNF-α) and soluble interleukin-2 receptors (sIL-2R) are elevated in patients with major depressive disorder: A meta-analysis and meta-regression
    • Liu Y, Ho RC and Mak A: Interleukin (IL)-6, tumour necrosis factor alpha (TNF-α) and soluble interleukin-2 receptors (sIL-2R) are elevated in patients with major depressive disorder: A meta-analysis and meta-regression. J Affect Disord 139: 230-239, 2012.
    • (2012) J Affect Disord , vol.139 , pp. 230-239
    • Liu, Y.1    Ho, R.C.2    Mak, A.3
  • 21
    • 0034008318 scopus 로고    scopus 로고
    • Synergistic effects of interleukin-1β, interleukin-6, and tumor necrosis factor-α: Central monoamine, corticosterone, and behavioral variations
    • Brebner K, Hayley S, Zacharko R, Merali Z and Anisman H: Synergistic effects of interleukin-1β, interleukin-6, and tumor necrosis factor-α: Central monoamine, corticosterone, and behavioral variations. Neuropsychopharmacology 22: 566-580, 2000.
    • (2000) Neuropsychopharmacology , vol.22 , pp. 566-580
    • Brebner, K.1    Hayley, S.2    Zacharko, R.3    Merali, Z.4    Anisman, H.5
  • 22
    • 0033984744 scopus 로고    scopus 로고
    • Inflammation, obesity, stress and coronary heart disease: Is interleukin-6 the link?
    • Yudkin JS, Kumari M, Humphries SE and Mohamed-Ali V: Inflammation, obesity, stress and coronary heart disease: Is interleukin-6 the link? Atherosclerosis 148: 209-214, 2000.
    • (2000) Atherosclerosis , vol.148 , pp. 209-214
    • Yudkin, J.S.1    Kumari, M.2    Humphries, S.E.3    Mohamed-Ali, V.4
  • 25
    • 0034051068 scopus 로고    scopus 로고
    • Age-associated increased interleukin-6 gene expression, late-life diseases, and frailty
    • Ershler WB and Keller ET: Age-associated increased interleukin-6 gene expression, late-life diseases, and frailty. Annu Rev Med 51: 245-270, 2000.
    • (2000) Annu Rev Med , vol.51 , pp. 245-270
    • Ershler, W.B.1    Keller, E.T.2
  • 28
    • 78149286160 scopus 로고    scopus 로고
    • Chronic unpredictable stress accelerates atherosclerosis through promoting inflammation in apolipoprotein
    • Zhang T, Chen Y, Liu H, Zhou Z, Zhai Y and Yang J: Chronic unpredictable stress accelerates atherosclerosis through promoting inflammation in apolipoprotein E knockout mice. Thromb Res 126: 386-392, 2010.
    • (2010) E Knockout Mice. Thromb Res , vol.126 , pp. 386-392
    • Zhang, T.1    Chen, Y.2    Liu, H.3    Zhou, Z.4    Zhai, Y.5    Yang, J.6
  • 29
    • 0028258379 scopus 로고
    • Changes in immunoglobulin, complement and acute phase protein levels in the depressed patients and normal controls
    • Song C, Dinan T and Leonard BE: Changes in immunoglobulin, complement and acute phase protein levels in the depressed patients and normal controls. J Affect Disord 30: 283-288, 1994.
    • (1994) J Affect Disord , vol.30 , pp. 283-288
    • Song, C.1    Dinan, T.2    Leonard, B.E.3
  • 30
    • 0032961728 scopus 로고    scopus 로고
    • High levels of circulating proinflammatory cytokines and leptin in urban, but not rural, Indians. A potential explanation for increased risk of diabetes and coronary heart disease
    • Yudkin JS, Yajnik CS, Mohamed-Ali V and Bulmer K: High levels of circulating proinflammatory cytokines and leptin in urban, but not rural, Indians. A potential explanation for increased risk of diabetes and coronary heart disease. Diabetes Care 22: 363-364, 1999.
    • (1999) Diabetes Care , vol.22 , pp. 363-364
    • Yudkin, J.S.1    Yajnik, C.S.2    Mohamed-Ali, V.3    Bulmer, K.4
  • 34
    • 0036232814 scopus 로고    scopus 로고
    • DNA microarray analysis of the aging brain
    • Prolla TA: DNA microarray analysis of the aging brain. Chem Senses 27: 299-306, 2002.
    • (2002) Chem Senses , vol.27 , pp. 299-306
    • Prolla, T.A.1
  • 35
    • 84871408947 scopus 로고    scopus 로고
    • Interleukin-1 beta,-2,-6 production, serum concentration and hypothalamic-pituitary-adrenal axis in patients with major depression
    • Choi SH and Suh KY: Interleukin-1 beta,-2,-6 production, serum concentration and hypothalamic-pituitary-adrenal axis in patients with major depression. J Korean Neuropsychiatr Assoc 37: 537-547, 1998.
    • (1998) J Korean Neuropsychiatr Assoc , vol.37 , pp. 537-547
    • Choi, S.H.1    Suh, K.Y.2
  • 37
    • 52649171401 scopus 로고    scopus 로고
    • Symptoms of postpartum depression associated with elevated levels of interleukin-1 beta during the first month postpartum
    • Corwin EJ, Johnston N and Pugh L: Symptoms of postpartum depression associated with elevated levels of interleukin-1 beta during the first month postpartum. Biol Res Nurs 10: 128-133, 2008.
    • (2008) Biol Res Nurs , vol.10 , pp. 128-133
    • Corwin, E.J.1    Johnston, N.2    Pugh, L.3
  • 38
    • 64649106914 scopus 로고    scopus 로고
    • Depressive symptomatology is associated with decreased interleukin-1 beta and increased interleukin-1 receptor antagonist levels in males
    • Ovaskainen Y, Koponen H, Jokelainen J, Keinänen-Kiukaanniemi S, Kumpusalo E and Vanhala M: Depressive symptomatology is associated with decreased interleukin-1 beta and increased interleukin-1 receptor antagonist levels in males. Psychiatry Res 167: 73-79, 2009.
    • (2009) Psychiatry Res , vol.167 , pp. 73-79
    • Ovaskainen, Y.1    Koponen, H.2    Jokelainen, J.3    Keinänen-Kiukaanniemi, S.4    Kumpusalo, E.5    Vanhala, M.6
  • 39
    • 0023755124 scopus 로고
    • Tissue-specific regulation of zinc metabolism and metallothionein genes by interleukin 1
    • Cousins RJ and Leinart AS: Tissue-specific regulation of zinc metabolism and metallothionein genes by interleukin 1. FASEB J 2: 2884-2890, 1988.
    • (1988) FASEB J , vol.2 , pp. 2884-2890
    • Cousins, R.J.1    Leinart, A.S.2
  • 44
    • 0034032594 scopus 로고    scopus 로고
    • Interleukin-10, interleukin-4, and transforming growth factor-β differentially regulate lipopolysaccharide-induced production of pro-inflammatory cytokines and nitric oxide in co-cultures of rat astroglial and microglial cells
    • Ledeboer A, Brevé JJ, Poole S, Tilders FJ and Van Dam AM: Interleukin-10, interleukin-4, and transforming growth factor-β differentially regulate lipopolysaccharide-induced production of pro-inflammatory cytokines and nitric oxide in co-cultures of rat astroglial and microglial cells. Glia 30: 134-142, 2000.
    • (2000) Glia , vol.30 , pp. 134-142
    • Ledeboer, A.1    Brevé, J.J.2    Poole, S.3    Tilders, F.J.4    van Dam, A.M.5
  • 45
  • 46
  • 47
    • 58449107369 scopus 로고    scopus 로고
    • Endothelial dysfunction: A potential therapeutic target for geriatric depression and brain amyloid deposition in Alzheimer’s disease?
    • Isingrini E, Desmidt T, Belzung C and Camus V: Endothelial dysfunction: A potential therapeutic target for geriatric depression and brain amyloid deposition in Alzheimer’s disease? Curr Opin Investig Drugs 10: 46-55, 2009.
    • (2009) Curr Opin Investig Drugs , vol.10 , pp. 46-55
    • Isingrini, E.1    Desmidt, T.2    Belzung, C.3    Camus, V.4
  • 49
    • 38649092266 scopus 로고    scopus 로고
    • IL-1β is an essential mediator of the antineurogenic and anhedonic effects of stress
    • Koo JW and Duman RS: IL-1β is an essential mediator of the antineurogenic and anhedonic effects of stress. Proc Natl Acad Sci USA 105: 751-756, 2008.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 751-756
    • Koo, J.W.1    Duman, R.S.2
  • 52
    • 0028968980 scopus 로고
    • Effect of bacterial endotoxin and interleukin-1 beta on hippocampal serotonergic neurotransmission, behavioral activity, and free corticosterone levels: An in vivo microdialysis study
    • Linthorst AC, Flachskamm C, Müller-Preuss P, Holsboer F and Reul JM: Effect of bacterial endotoxin and interleukin-1 beta on hippocampal serotonergic neurotransmission, behavioral activity, and free corticosterone levels: An in vivo microdialysis study. J Neurosci 15: 2920-2934, 1995.
    • (1995) J Neurosci , vol.15 , pp. 2920-2934
    • Linthorst, A.C.1    Flachskamm, C.2    Müller-Preuss, P.3    Holsboer, F.4    Reul, J.M.5
  • 53
    • 0028092812 scopus 로고
    • Local administration of recombinant human interleukin-1 beta in the rat hippocampus increases serotonergic neurotransmission, hypothalamic-pituitary-adrenocortical axis activity, and body temperature
    • Linthorst AC, Flachskamm C, Holsboer F and Reul JM: Local administration of recombinant human interleukin-1 beta in the rat hippocampus increases serotonergic neurotransmission, hypothalamic-pituitary-adrenocortical axis activity, and body temperature. Endocrinology 135: 520-532, 1994.
    • (1994) Endocrinology , vol.135 , pp. 520-532
    • Linthorst, A.C.1    Flachskamm, C.2    Holsboer, F.3    Reul, J.M.4
  • 54
    • 0027176336 scopus 로고
    • Interleukin-1 beta augments release of norepinephrine, dopamine, and serotonin in the rat anterior hypothalamus
    • Shintani F, Kanba S, Nakaki T, Nibuya M, Kinoshita N, Suzuki E, Yagi G, Kato R and Asai M: Interleukin-1 beta augments release of norepinephrine, dopamine, and serotonin in the rat anterior hypothalamus. J Neurosci 13: 3574-3581, 1993.
    • (1993) J Neurosci , vol.13 , pp. 3574-3581
    • Shintani, F.1    Kanba, S.2    Nakaki, T.3    Nibuya, M.4    Kinoshita, N.5    Suzuki, E.6    Yagi, G.7    Kato, R.8    Asai, M.9
  • 55
    • 33748808678 scopus 로고    scopus 로고
    • The proinflammatory cytokines interleukin-1beta and tumor necrosis factor-alpha activate serotonin transporters
    • Zhu CB, Blakely RD and Hewlett WA: The proinflammatory cytokines interleukin-1beta and tumor necrosis factor-alpha activate serotonin transporters. Neuropsychopharmacology 31: 2121-2131, 2006.
    • (2006) Neuropsychopharmacology , vol.31 , pp. 2121-2131
    • Zhu, C.B.1    Blakely, R.D.2    Hewlett, W.A.3
  • 57
    • 74949123761 scopus 로고    scopus 로고
    • P2X7-dependent release of interleukin-1β and nociception in the spinal cord following lipopolysaccharide
    • Clark AK, Staniland AA, Marchand F, Kaan TK, McMahon SB and Malcangio M: P2X7-dependent release of interleukin-1β and nociception in the spinal cord following lipopolysaccharide. J Neurosci 30: 573-582, 2010.
    • (2010) J Neurosci , vol.30 , pp. 573-582
    • Clark, A.K.1    Staniland, A.A.2    Marchand, F.3    Kaan, T.K.4    McMahon, S.B.5    Malcangio, M.6
  • 58
    • 84856002812 scopus 로고    scopus 로고
    • Distinct regulation by lipopolysaccharides of the expression of interleukin-1β by murine macrophages and salivary glands
    • Seil M, El Ouaaliti M, Abdou Foumekoye S, Pochet S and Dehaye JP: Distinct regulation by lipopolysaccharides of the expression of interleukin-1β by murine macrophages and salivary glands. Innate Immun 18: 14-24, 2012.
    • (2012) Innate Immun , vol.18 , pp. 14-24
    • Seil, M.1    El Ouaaliti, M.2    Abdou Foumekoye, S.3    Pochet, S.4    Dehaye, J.P.5
  • 59
    • 77950941000 scopus 로고    scopus 로고
    • Single nucleotide polymorphisms that were identified in affective mood disorders affect ATP-activated P2X7 receptor functions
    • Roger S, Mei ZZ, Baldwin JM, Dong L, Bradley H, Baldwin SA, Surprenant A and Jiang LH: Single nucleotide polymorphisms that were identified in affective mood disorders affect ATP-activated P2X7 receptor functions. J Psychiatr Res 44: 347-355, 2010.
    • (2010) J Psychiatr Res , vol.44 , pp. 347-355
    • Roger, S.1    Mei, Z.Z.2    Baldwin, J.M.3    Dong, L.4    Bradley, H.5    Baldwin, S.A.6    Surprenant, A.7    Jiang, L.H.8
  • 61
    • 58549092549 scopus 로고    scopus 로고
    • Behavioral profile of P2X7 receptor knockout mice in animal models of depression and anxiety: Relevance for neuropsychiatric disorders
    • Basso AM, Bratcher NA, Harris RR, Jarvis MF, Decker MW and Rueter LE: Behavioral profile of P2X7 receptor knockout mice in animal models of depression and anxiety: Relevance for neuropsychiatric disorders. Behav Brain Res 198: 83-90, 2009.
    • (2009) Behav Brain Res , vol.198 , pp. 83-90
    • Basso, A.M.1    Bratcher, N.A.2    Harris, R.R.3    Jarvis, M.F.4    Decker, M.W.5    Rueter, L.E.6
  • 62
    • 84876784736 scopus 로고    scopus 로고
    • Interleukin-1 beta converting enzyme is necessary for development of depression-like behavior following intracerebroventricular administration of lipopolysaccharide to mice
    • Lawson MA, McCusker RH and Kelley KW: Interleukin-1 beta converting enzyme is necessary for development of depression-like behavior following intracerebroventricular administration of lipopolysaccharide to mice. J Neuroinflammation 10: 54, 2013.
    • (2013) J Neuroinflammation , vol.10 , pp. 54
    • Lawson, M.A.1    McCusker, R.H.2    Kelley, K.W.3
  • 65
    • 0030220185 scopus 로고    scopus 로고
    • Tricyclic antidepressants inhibit IL-6, IL-1 β and TNF-α release in human blood monocytes and IL-2 and interferon-γ in T cells
    • Xia Z, DePierre JW and Nässberger L: Tricyclic antidepressants inhibit IL-6, IL-1 β and TNF-α release in human blood monocytes and IL-2 and interferon-γ in T cells. Immunopharmacology 34: 27-37, 1996.
    • (1996) Immunopharmacology , vol.34 , pp. 27-37
    • Xia, Z.1    Depierre, J.W.2    Nässberger, L.3
  • 68
    • 0034118647 scopus 로고    scopus 로고
    • Psychiatric side effects of interferon therapy: Prevalence, proposed mechanisms, and future directions
    • Trask PC, Esper P, Riba M and Redman B: Psychiatric side effects of interferon therapy: Prevalence, proposed mechanisms, and future directions. J Clin Oncol 18: 2316-2326, 2000.
    • (2000) J Clin Oncol , vol.18 , pp. 2316-2326
    • Trask, P.C.1    Esper, P.2    Riba, M.3    Redman, B.4
  • 69
    • 0031821012 scopus 로고    scopus 로고
    • Hepatitis C and depression
    • Yates WR and Gleason O: Hepatitis C and depression. Depress Anxiety 7: 188-193, 1998.
    • (1998) Depress Anxiety , vol.7 , pp. 188-193
    • Yates, W.R.1    Gleason, O.2
  • 71
    • 0030835875 scopus 로고    scopus 로고
    • Hepatitis B: Diagnosis, prevention, and treatment
    • Gitlin N: Hepatitis B: Diagnosis, prevention, and treatment. Clin Chem 43: 1500-1506, 1997.
    • (1997) Clin Chem , vol.43 , pp. 1500-1506
    • Gitlin, N.1
  • 72
    • 18844398845 scopus 로고    scopus 로고
    • Chronic hepatitis C, depression and interferon
    • Horsmans Y: Chronic hepatitis C, depression and interferon. J Hepatol 42: 788-789, 2005.
    • (2005) J Hepatol , vol.42 , pp. 788-789
    • Horsmans, Y.1
  • 73
    • 34447628313 scopus 로고    scopus 로고
    • Depression following pegylated interferon-alpha: Characteristics and vulnerability
    • Lotrich FE, Rabinovitz M, Gironda P and Pollock BG: Depression following pegylated interferon-alpha: Characteristics and vulnerability. J Psychosom Res 63: 131-135, 2007.
    • (2007) J Psychosom Res , vol.63 , pp. 131-135
    • Lotrich, F.E.1    Rabinovitz, M.2    Gironda, P.3    Pollock, B.G.4
  • 74
    • 42249115877 scopus 로고    scopus 로고
    • Neuroinflammation mediated by IL-1β increases susceptibility of dopamine neurons to degeneration in an animal model of Parkinson’s disease
    • Koprich JB, Reske-Nielsen C, Mithal P and Isacson O: Neuroinflammation mediated by IL-1β increases susceptibility of dopamine neurons to degeneration in an animal model of Parkinson’s disease. J Neuroinflammation 5: 8, 2008.
    • (2008) J Neuroinflammation , vol.5 , pp. 8
    • Koprich, J.B.1    Reske-Nielsen, C.2    Mithal, P.3    Isacson, O.4
  • 76
    • 84908072658 scopus 로고    scopus 로고
    • Depression and anxiety symptoms post-stroke/TIA: Prevalence and associations in cross-sectional data from a regional stroke registry
    • Broomfield NM, Quinn TJ, Abdul-Rahim AH, Walters MR and Evans JJ: Depression and anxiety symptoms post-stroke/TIA: Prevalence and associations in cross-sectional data from a regional stroke registry. BMC Neurol 14: 198, 2014.
    • (2014) BMC Neurol , vol.14 , pp. 198
    • Broomfield, N.M.1    Quinn, T.J.2    Abdul-Rahim, A.H.3    Walters, M.R.4    Evans, J.J.5
  • 77
    • 84897951150 scopus 로고    scopus 로고
    • Stroke lesions and post-stroke depression among survivors in Ibadan, Nigeria
    • Ojagbemi A, Owolabi M, Atalabi M and Baiyewu O: Stroke lesions and post-stroke depression among survivors in Ibadan, Nigeria. Afr J Med Med Sci 42: 245-251, 2013.
    • (2013) Afr J Med Med Sci , vol.42 , pp. 245-251
    • Ojagbemi, A.1    Owolabi, M.2    Atalabi, M.3    Baiyewu, O.4
  • 78
    • 0031939143 scopus 로고    scopus 로고
    • The Sunnybrook Stroke Study: A prospective study of depressive symptoms and functional outcome
    • Herrmann N, Black SE, Lawrence J, Szekely C and Szalai JP: The Sunnybrook Stroke Study: A prospective study of depressive symptoms and functional outcome. Stroke 29: 618-624, 1998.
    • (1998) Stroke , vol.29 , pp. 618-624
    • Herrmann, N.1    Black, S.E.2    Lawrence, J.3    Szekely, C.4    Szalai, J.P.5
  • 79
    • 44449172008 scopus 로고    scopus 로고
    • White matter hyperintensities in late life depression: A systematic review
    • Herrmann LL, Le Masurier M and Ebmeier KP: White matter hyperintensities in late life depression: A systematic review. J Neurol Neurosurg Psychiatry 79: 619-624, 2008.
    • (2008) J Neurol Neurosurg Psychiatry , vol.79 , pp. 619-624
    • Herrmann, L.L.1    Le Masurier, M.2    Ebmeier, K.P.3
  • 80
    • 33747781747 scopus 로고    scopus 로고
    • Inflammation in stroke and focal cerebral ischemia
    • Huang J, Upadhyay UM and Tamargo RJ: Inflammation in stroke and focal cerebral ischemia. Surg Neurol 66: 232-245, 2006.
    • (2006) Surg Neurol , vol.66 , pp. 232-245
    • Huang, J.1    Upadhyay, U.M.2    Tamargo, R.J.3
  • 83
    • 57749179191 scopus 로고    scopus 로고
    • The inflammatory & neurodegenerative (I&ND) hypothesis of depression: Leads for future research and new drug developments in depression
    • Maes M, Yirmyia R, Noraberg J, Brene S, Hibbeln J, Perini G, Kubera M, Bob P, Lerer B and Maj M: The inflammatory & neurodegenerative (I&ND) hypothesis of depression: Leads for future research and new drug developments in depression. Metab Brain Dis 24: 27-53, 2009.
    • (2009) Metab Brain Dis , vol.24 , pp. 27-53
    • Maes, M.1    Yirmyia, R.2    Noraberg, J.3    Brene, S.4    Hibbeln, J.5    Perini, G.6    Kubera, M.7    Bob, P.8    Lerer, B.9    Maj, M.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.