Paroxetine for the prevention of depression induced by high-dose interferon alfa

New England Journal of Medicine

Volumn 344, Issue 13, 2001, Pages 961-966

  Musselman, Dominique L ^a   Lawson, David H ^a   Gumnick, Jane F ^a   Manatunga, Amita K ^b   Penna, Suzanne ^a   Goodkin, Rebecca S ^a   Greiner, Kristen ^a   Nemeroff, Charles B ^a   Miller, Andrew H ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b EMORY UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; PAROXETINE; PLACEBO;

ADULT; ANXIETY NEUROSIS; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DEPRESSION; DOUBLE BLIND PROCEDURE; DRUG MEGADOSE; FEMALE; HUMAN; MALE; MELANOMA; NEUROTOXICITY; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; TREATMENT OUTCOME;

ADULT; AGED; ANTIDEPRESSIVE AGENTS, SECOND-GENERATION; ANTINEOPLASTIC AGENTS; DEPRESSIVE DISORDER; DISEASE-FREE SURVIVAL; DOUBLE-BLIND METHOD; FEMALE; HUMANS; INTERFERON ALFA-2B; MALE; MELANOMA; MIDDLE AGED; PAROXETINE; SEROTONIN UPTAKE INHIBITORS;

EID: 0035967235     PISSN: 00284793     EISSN: None     Source Type: Journal    
DOI: 10.1056/NEJM200103293441303     Document Type: Article

References (34)

1. A perspective on the clinical effectiveness and tolerance of interferon-alpha
2. Hepatitis C
3. Mood and cognitive side effects of interferon-alpha therapy
4. Sickness behavior as a new target for drug development
5. Suicide associated with alfa-interferon therapy for chronic viral hepatitis
6. Endotoxin produces a depressive-like episode in rats
7. 1 receptors mediate consensus interferon-alpha YM643-induced depression-like behavior in mice
8. Selective serotonin reuptake inhibitors
9. "Mini-Mental State": A practical method for grading the cognitive state of patients for the clinician
10. A rating scale for depression
11. The Carroll rating scale for depression. I. Development, reliability and validation
12. The Hamilton anxiety scale: Reliability, validity and sensitivity to change in anxiety and depressive disorders
13. Treatment of neurotoxic side effects of interferon-alpha with naltrexone
14. Depression and abnormal illness behavior in cancer patients
15. Retinopathy associated with high dose interferon alpha therapy
16. Successful treatment of interferon alfa-induced mood disorder with nortriptyline
17. Fluoxetine treatment of depression caused by interferon-alpha
18. Five cases of interferon-alfa-induced depression treated with antidepressant therapy
19. Treatment of depression improves adherence to interferon beta-1b therapy for multiple sclerosis
20. Prediction of the depressive effects of interferon alfa therapy by the patient's initial affective state
21. The effects of interferon-alpha on the production and action of other cytokines
22. Cytokines and brain function: Relevance to interferon-alpha-induced mood and cognitive changes
23. Implications of interferon-induced tryptophan catabolism in cancer, autoimmune diseases and AIDS
24. Interferon-alpha stimulates the hypothalamic-pituitary-adrenal axis in vivo and in vitro
25. Antidepressants and hypothalamic-pituitary-adrenocortical regulation
26. Induction of hyperthyroidism by interferon-alpha-2b
27. Primary hypothyroidism associated with interferon therapy of breast cancer
28. Immunosuppression by glucocorticoids: Inhibition of NF-kappa B activity through induction of I kappa B synthesis
29. Negative immunoregulatory effects of antidepressants: Inhibition of interferon-gamma and stimulation of interleukin-10 secretion