-
1
-
-
42549138499
-
Immunotherapy of established (Pre)malignant disease by synthetic long peptide vaccines. Nat
-
Melief, C. J. & van der Burg, S. H. Immunotherapy of established (pre)malignant disease by synthetic long peptide vaccines. Nat. Rev. Cancer 8, 351-360 (2008).
-
(2008)
Rev. Cancer
, vol.8
, pp. 351-360
-
-
Melief, C.J.1
Van Der Burg, S.H.2
-
2
-
-
14644390867
-
Rapid and strong human CD8C T cell responses to vaccination with peptide, IFA, and CpG oligodeoxynucleotide 7909
-
Speiser, D. E. et al. Rapid and strong human CD8C T cell responses to vaccination with peptide, IFA, and CpG oligodeoxynucleotide 7909. J. Clin. Invest. 115, 739-746 (2005).
-
(2005)
J. Clin. Invest
, vol.115
, pp. 739-746
-
-
Speiser, D.E.1
-
3
-
-
59849116262
-
Immunization with analog peptide in combination with CpG and montanide expands tumor antigen-specific CD8C T cells in melanoma patients
-
Fourcade, J. et al. Immunization with analog peptide in combination with CpG and montanide expands tumor antigen-specific CD8C T cells in melanoma patients. J. Immunother. 31, 781-791 (2008).
-
(2008)
J. Immunother
, vol.31
, pp. 781-791
-
-
Fourcade, J.1
-
4
-
-
84878469107
-
Persistent antigen at vaccination sites induces tumor-specific CD8C T cell sequestration, dysfunction and deletion
-
Hailemichael, Y. et al. Persistent antigen at vaccination sites induces tumor-specific CD8C T cell sequestration, dysfunction and deletion. Nat. Med. 19, 465-472 (2013).
-
(2013)
Nat. Med
, vol.19
, pp. 465-472
-
-
Hailemichael, Y.1
-
5
-
-
35148889797
-
Exploiting lymphatic transport and complement activation in nanoparticle vaccines
-
Reddy, S. T. et al. Exploiting lymphatic transport and complement activation in nanoparticle vaccines. Nat. Biotechnol. 25, 1159-1164 (2007).
-
(2007)
Nat. Biotechnol
, vol.25
, pp. 1159-1164
-
-
Reddy, S.T.1
-
6
-
-
79951899834
-
Interbilayer-crosslinked multilamellar vesicles as synthetic vaccines for potent humoral and cellular immune responses
-
Moon, J. J. et al. Interbilayer-crosslinked multilamellar vesicles as synthetic vaccines for potent humoral and cellular immune responses. Nat. Mater. 10, 243-251 (2011).
-
(2011)
Nat. Mater
, vol.10
, pp. 243-251
-
-
Moon, J.J.1
-
7
-
-
84865416734
-
Imageable antigen-presenting gold nanoparticle vaccines for e_ective cancer immunotherapy in vivo
-
Lee, I. H. et al. Imageable antigen-presenting gold nanoparticle vaccines for e_ective cancer immunotherapy in vivo. Angew Chem. Int. Ed. 51, 8800-8805 (2012).
-
(2012)
Angew Chem. Int. Ed
, vol.51
, pp. 8800-8805
-
-
Lee, I.H.1
-
8
-
-
84884676871
-
Generation of effector memory T cell-based mucosal and systemic immunity with pulmonary nanoparticle vaccination
-
204ra130
-
Li, A. V. et al. Generation of effector memory T cell-based mucosal and systemic immunity with pulmonary nanoparticle vaccination. Sci. Transl. Med. 5, 204ra130 (2013).
-
(2013)
Sci. Transl. Med
, vol.5
-
-
Li, A.V.1
-
9
-
-
84908589994
-
Enhancing efficacy of anticancer vaccines by targeted delivery to tumor-draining lymph nodes
-
Jeanbart, L. et al. Enhancing efficacy of anticancer vaccines by targeted delivery to tumor-draining lymph nodes. Cancer Immunol. Res. 2, 436-447 (2014).
-
(2014)
Cancer Immunol. Res
, vol.2
, pp. 436-447
-
-
Jeanbart, L.1
-
10
-
-
84899457547
-
Nanoparticle-delivered transforming growth factor-beta siRNA enhances vaccination against advanced melanoma by modifying tumor microenvironment
-
Xu, Z., Wang, Y., Zhang, L. & Huang, L. Nanoparticle-delivered transforming growth factor-beta siRNA enhances vaccination against advanced melanoma by modifying tumor microenvironment. ACS Nano 8, 3636-3645 (2014).
-
(2014)
ACS Nano
, vol.8
, pp. 3636-3645
-
-
Xu, Z.1
Wang, Y.2
Zhang, L.3
Huang, L.4
-
11
-
-
84897954314
-
Structure-based programming of lymph-node targeting in molecular vaccines
-
Liu, H. et al. Structure-based programming of lymph-node targeting in molecular vaccines. Nature 507, 519-522 (2014).
-
(2014)
Nature
, vol.507
, pp. 519-522
-
-
Liu, H.1
-
12
-
-
84919667582
-
CD40-targeted dendritic cell delivery of PLGA-nanoparticle vaccines induce potent anti-tumor responses
-
Rosalia, R. A. et al. CD40-targeted dendritic cell delivery of PLGA-nanoparticle vaccines induce potent anti-tumor responses. Biomaterials 40, 88-97 (2015).
-
(2015)
Biomaterials
, vol.40
, pp. 88-97
-
-
Rosalia, R.A.1
-
13
-
-
84969174910
-
Modular vaccine design using carrier-free capsules assembled from polyionic immune signals. ACS Biomater
-
Chiu, Y. C., Gammon, J. M., Andorko, J. I., Tostanoski, L. H. & Jewell, C. M. Modular vaccine design using carrier-free capsules assembled from polyionic immune signals. ACS Biomater. Sci. Eng. 1, 1200-1205 (2015).
-
(2015)
Sci. Eng
, vol.1
, pp. 1200-1205
-
-
Chiu, Y.C.1
Gammon, J.M.2
Orko, J.I.3
Tostanoski, L.H.4
Jewell, C.M.5
-
14
-
-
85016848613
-
Nanoparticle drug delivery systems designed to improve cancer vaccines and immunotherapy
-
Fan, Y. & Moon, J. J. Nanoparticle drug delivery systems designed to improve cancer vaccines and immunotherapy. Vaccines (Basel)3, 662-685 (2015).
-
(2015)
Vaccines (Basel)3
, pp. 662-685
-
-
Fan, Y.1
Moon, J.J.2
-
15
-
-
84960114076
-
Situ vaccination with cowpea mosaic virus nanoparticles suppresses metastatic cancer
-
Lizotte, P. H. et al. In situ vaccination with cowpea mosaic virus nanoparticles suppresses metastatic cancer. Nat. Nanotech. 13, 295-303 (2016).
-
(2016)
Nat. Nanotech. 13, 295-303
-
-
Lizotte, P.H.1
-
16
-
-
84920956731
-
Predicting immunogenic tumour mutations by combining mass spectrometry and exome sequencing
-
Yadav, M. et al. Predicting immunogenic tumour mutations by combining mass spectrometry and exome sequencing. Nature 515, 572-576 (2014).
-
(2014)
Nature
, vol.515
, pp. 572-576
-
-
Yadav, M.1
-
17
-
-
84928811341
-
Mutant MHC class II epitopes drive therapeutic immune responses to cancer
-
Kreiter, S. et al. Mutant MHC class II epitopes drive therapeutic immune responses to cancer. Nature 520, 692-696 (2015).
-
(2015)
Nature
, vol.520
, pp. 692-696
-
-
Kreiter, S.1
-
18
-
-
84904472602
-
Systematic identification of personal tumor-specific neoantigens in chronic lymphocytic leukemia
-
Rajasagi, M. et al. Systematic identification of personal tumor-specific neoantigens in chronic lymphocytic leukemia. Blood 124, 453-462 (2014).
-
(2014)
Blood
, vol.124
, pp. 453-462
-
-
Rajasagi, M.1
-
19
-
-
84928770388
-
Neoantigens in cancer immunotherapy
-
Schumacher, T. N. & Schreiber, R. D. Neoantigens in cancer immunotherapy. Science 348, 69-74 (2015).
-
(2015)
Science
, vol.348
, pp. 69-74
-
-
Schumacher, T.N.1
Schreiber, R.D.2
-
20
-
-
35148815670
-
Mechanisms and optimization of in vivo delivery of lipophilic siRNAs. Nat
-
Wolfrum, C. et al. Mechanisms and optimization of in vivo delivery of lipophilic siRNAs. Nat. Biotechnol. 25, 1149-1157 (2007).
-
(2007)
Biotechnol
, vol.25
, pp. 1149-1157
-
-
Wolfrum, C.1
-
21
-
-
84873616727
-
Colocalized delivery of adjuvant and antigen using nanolipoprotein particles enhances the immune response to recombinant antigens
-
Fischer, N. O. et al. Colocalized delivery of adjuvant and antigen using nanolipoprotein particles enhances the immune response to recombinant antigens. J. Am. Chem. Soc. 135, 2044-2047 (2013).
-
(2013)
J. Am. Chem. Soc
, vol.135
, pp. 2044-2047
-
-
Fischer, N.O.1
-
22
-
-
84892865604
-
A statin-loaded reconstituted high-density lipoprotein nanoparticle inhibits atherosclerotic plaque inflammation. Nat
-
Duivenvoorden, R. et al. A statin-loaded reconstituted high-density lipoprotein nanoparticle inhibits atherosclerotic plaque inflammation. Nat. Commun. 5, 3065 (2014).
-
(2014)
Commun
, vol.5
, pp. 3065
-
-
Duivenvoorden, R.1
-
23
-
-
84980468985
-
-
Li, D., Gordon, S., Schwendeman, A. & Remaley, A. T. Apolipoprotein Mimetics in the Management of Human Disease 29-42 (Springer, 2015).
-
(2015)
Apolipoprotein Mimetics in the Management of Human Disease 29-42
-
-
Li, D.1
Gordon, S.2
Schwendeman, A.3
Remaley, A.T.4
-
24
-
-
44949234467
-
Single-dose intravenous infusion of ETC-642, a 22-Mer ApoA-I analogue and phospholipids complex, elevates HDL-C in atherosclerosis patients
-
Khan, M., Lalwani, N., Drake, S., Crockatt, J. & Dasseux, J. Single-dose intravenous infusion of ETC-642, a 22-Mer ApoA-I analogue and phospholipids complex, elevates HDL-C in atherosclerosis patients. Circulation 108, 563-564 (2003).
-
(2003)
Circulation
, vol.108
, pp. 563-564
-
-
Khan, M.1
Lalwani, N.2
Drake, S.3
Crockatt, J.4
Dasseux, J.5
-
25
-
-
85051438503
-
Single-dose tolerability, pharmacokinetics, and cholesterol mobilization in HDL-C fraction following intravenous administration of ETC-642, a 22-mer ApoA-I analogue and phospholipids complex
-
Miles, J. et al. Single-dose tolerability, pharmacokinetics, and cholesterol mobilization in HDL-C fraction following intravenous administration of ETC-642, a 22-mer ApoA-I analogue and phospholipids complex, in atherosclerosis patients. Proc. Arterioscler. Thromb. Vasc. Biol. 24, E19 (2004).
-
(2004)
Atherosclerosis Patients. Proc. Arterioscler. Thromb. Vasc. Biol
, vol.24
-
-
Miles, J.1
-
26
-
-
84961967585
-
High-density lipoproteins: Nature's multifunctional nanoparticles
-
Kuai, R., Li, D., Chen, Y. E., Moon, J. J. & Schwendeman, A. High-density lipoproteins: Nature's multifunctional nanoparticles. ACS Nano 10, 3015-3041 (2016).
-
(2016)
ACS Nano
, vol.10
, pp. 3015-3041
-
-
Kuai, R.1
Li, D.2
Chen, Y.E.3
Moon, J.J.4
Schwendeman, A.5
-
27
-
-
51049092308
-
A_ecting the clearance and biodistribution of polymeric nanoparticles
-
Alexis, F., Pridgen, E., Molnar, L. K. & Farokhzad, O. C. Factors a_ecting the clearance and biodistribution of polymeric nanoparticles. Mol. Pharmacol. 5, 505-515 (2008).
-
(2008)
Mol. Pharmacol
, vol.5
, pp. 505-515
-
-
Alexis, F.1
Pridgen, E.2
Molnar, L.K.3
Farokhzad, O.C.F.4
-
28
-
-
84939575307
-
A review of clinical translation of inorganic nanoparticles
-
Anselmo, A. C. & Mitragotri, S. A review of clinical translation of inorganic nanoparticles. AAPS J. 17, 1041-1054 (2015).
-
(2015)
AAPS J
, vol.17
, pp. 1041-1054
-
-
Anselmo, A.C.1
Mitragotri, S.2
-
29
-
-
78650231557
-
Antigen delivery to dendritic cells by poly(Propylene sulfide) nanoparticles with disulfide conjugated peptides: Cross-presentation and T cell activation
-
Hirosue, S., Kourtis, I. C., van der Vlies, A. J., Hubbell, J. A. & Swartz, M. A. Antigen delivery to dendritic cells by poly(propylene sulfide) nanoparticles with disulfide conjugated peptides: cross-presentation and T cell activation. Vaccine 28, 7897-7906 (2010).
-
(2010)
Vaccine
, vol.28
, pp. 7897-7906
-
-
Hirosue, S.1
Kourtis, I.C.2
Van Der Vlies, A.J.3
Hubbell, J.A.4
Swartz, M.A.5
-
30
-
-
84884296628
-
Dipeptides promote folding and peptide binding of MHC class I molecules
-
Saini, S. K. et al. Dipeptides promote folding and peptide binding of MHC class I molecules. Proc. Natl Acad. Sci. USA 110, 15383-15388 (2013).
-
(2013)
Proc. Natl Acad. Sci. USA
, vol.110
, pp. 15383-15388
-
-
Saini, S.K.1
-
31
-
-
85051431245
-
-
US National Library of Medicine ClinicalTrials.gov [online] (2009); http://clinicaltrials.gov/show/NCT00819806 (Accessed 9 January 2015).
-
(2009)
-
-
-
32
-
-
85051417955
-
-
US National Library of Medicine ClinicalTrials.gov [online] (2008); http://clinicaltrials.gov/ct2/show/record/NCT00640861 (Accessed 9 January 2015).
-
(2008)
-
-
-
33
-
-
84862859820
-
Safety, activity, and immune correlates of anti-PD-1 antibody in cancer
-
Topalian, S. L. et al. Safety, activity, and immune correlates of anti-PD-1 antibody in cancer. N. Engl. J. Med. 366, 2443-2454 (2012).
-
(2012)
N. Engl. J. Med
, vol.366
, pp. 2443-2454
-
-
Topalian, S.L.1
-
34
-
-
84959529731
-
PD-L1 (B7-H1) and PD-1 pathway blockade for cancer therapy: Mechanisms, response biomarkers, and combinations
-
328rv324
-
Zou, W., Wolchok, J. D. & Chen, L. PD-L1 (B7-H1) and PD-1 pathway blockade for cancer therapy: mechanisms, response biomarkers, and combinations. Sci. Transl. Med. 8, 328rv324 (2016).
-
(2016)
Sci. Transl. Med
, vol.8
-
-
Zou, W.1
Wolchok, J.D.2
Chen, L.3
-
35
-
-
84976406873
-
Neoantigen landscape dynamics during human melanoma-T cell interactions
-
Verdegaal, E. M. et al. Neoantigen landscape dynamics during human melanoma-T cell interactions. Nature 536, 91-95 (2016).
-
(2016)
Nature
, vol.536
, pp. 91-95
-
-
Verdegaal, E.M.1
-
36
-
-
84992315668
-
Eradication of large established tumors in mice by combination immunotherapy that engages innate and adaptive immune responses
-
Moynihan, K. D. et al. Eradication of large established tumors in mice by combination immunotherapy that engages innate and adaptive immune responses. Nat. Med. http://dx.doi.org/10.1038/nm.4200 (2016).
-
Nat. Med.
-
-
Moynihan, K.D.1
-
37
-
-
84875039618
-
Combining radiotherapy and cancer immunotherapy: A paradigm shift
-
Formenti, S. C. & Demaria, S. Combining radiotherapy and cancer immunotherapy: a paradigm shift. J. Natl. Cancer Inst. 105, 256-265 (2013).
-
(2013)
J. Natl. Cancer Inst
, vol.105
, pp. 256-265
-
-
Formenti, S.C.1
Demaria, S.2
-
38
-
-
84876961766
-
Chemotherapy acts as an adjuvant to convert the tumor microenvironment into a highly permissive state for vaccination-induced antitumor immunity
-
Kang, T. H. et al. Chemotherapy acts as an adjuvant to convert the tumor microenvironment into a highly permissive state for vaccination-induced antitumor immunity. Cancer Res. 73, 2493-2504 (2013).
-
(2013)
Cancer Res
, vol.73
, pp. 2493-2504
-
-
Kang, T.H.1
-
39
-
-
84920921528
-
Checkpoint blockade cancer immunotherapy targets tumour-specific mutant antigens
-
Gubin, M. M. et al. Checkpoint blockade cancer immunotherapy targets tumour-specific mutant antigens. Nature 515, 577-581 (2014).
-
(2014)
Nature
, vol.515
, pp. 577-581
-
-
Gubin, M.M.1
-
40
-
-
84880276438
-
Mining exomic sequencing data to identify mutated antigens recognized by adoptively transferred tumor-reactive T cells. Nat
-
Robbins, P. F. et al. Mining exomic sequencing data to identify mutated antigens recognized by adoptively transferred tumor-reactive T cells. Nat. Med. 19, 747-752 (2013).
-
(2013)
Med
, vol.19
, pp. 747-752
-
-
Robbins, P.F.1
-
41
-
-
84961323160
-
High-throughput epitope discovery reveals frequent recognition of neo-antigens by CD4C T cells in human melanoma
-
Linnemann, C. et al. High-throughput epitope discovery reveals frequent recognition of neo-antigens by CD4C T cells in human melanoma. Nat. Med. 21, 81-85 (2015).
-
(2015)
Nat. Med
, vol.21
, pp. 81-85
-
-
Linnemann, C.1
-
42
-
-
77957737792
-
Efficient delivery of payload into tumor cells in a controlled manner by TAT and thiolytic cleavable PEG co-modified liposomes
-
Kuai, R. et al. Efficient delivery of payload into tumor cells in a controlled manner by TAT and thiolytic cleavable PEG co-modified liposomes. Mol. Pharmacol. 7, 1816-1826 (2010).
-
(2010)
Mol. Pharmacol
, vol.7
, pp. 1816-1826
-
-
Kuai, R.1
-
43
-
-
0033012030
-
An advanced culture method for generating large quantities of highly pure dendritic cells from mouse bone marrow
-
Lutz, M. B. et al. An advanced culture method for generating large quantities of highly pure dendritic cells from mouse bone marrow. J. Immunol. Methods 223, 77-92 (1999).
-
(1999)
J. Immunol. Methods
, vol.223
, pp. 77-92
-
-
Lutz, M.B.1
-
44
-
-
84866670385
-
Releasable layer-by-layer assembly of stabilized lipid nanocapsules on microneedles for enhanced transcutaneous vaccine delivery
-
DeMuth, P. C., Moon, J. J., Suh, H., Hammond, P. T. & Irvine, D. J. Releasable layer-by-layer assembly of stabilized lipid nanocapsules on microneedles for enhanced transcutaneous vaccine delivery. ACS Nano 6, 8041-8051 (2012).
-
(2012)
ACS Nano
, vol.6
, pp. 8041-8051
-
-
Demuth, P.C.1
Moon, J.J.2
Suh, H.3
Hammond, P.T.4
Irvine, D.J.5
-
45
-
-
17144437129
-
Mouse macrophage metalloelastase gene transfer into a murine melanoma suppresses primary tumor growth by halting angiogenesis
-
Gorrin-Rivas, M. J. et al. Mouse macrophage metalloelastase gene transfer into a murine melanoma suppresses primary tumor growth by halting angiogenesis. Clin. Cancer Res. 6, 1647-1654 (2000).
-
(2000)
Clin. Cancer Res
, vol.6
, pp. 1647-1654
-
-
Gorrin-Rivas, M.J.1
-
46
-
-
84937771150
-
Whole-animal imaging and flow cytometric techniques for analysis of antigen-specific CD8C T cell responses after nanoparticle vaccination
-
Ochyl, L. J. & Moon, J. J.Whole-animal imaging and flow cytometric techniques for analysis of antigen-specific CD8C T cell responses after nanoparticle vaccination. J. Vis. Exp. 98, e52771 (2015).
-
(2015)
Vis. Exp
, vol.98
-
-
Ochyl, L.J.1
Moon, J.J.2
-
47
-
-
84936768744
-
Cationic liposome-hyaluronic acid hybrid nanoparticles for intranasal vaccination with subunit antigens
-
Fan, Y., Sahdev, P., Ochyl, L. J., J, J. A. & Moon, J. J. Cationic liposome-hyaluronic acid hybrid nanoparticles for intranasal vaccination with subunit antigens. J. Control Release 208, 121-129 (2015).
-
(2015)
J. Control Release
, vol.208
, pp. 121-129
-
-
Fan, Y.1
Sahdev, P.2
Ochyl, L.J.3
Moon, J.J.4
-
48
-
-
84859394263
-
Cancer stem cell vaccination confers significant antitumor immunity
-
Ning, N. et al. Cancer stem cell vaccination confers significant antitumor immunity. Cancer Res. 72, 1853-1864 (2012).
-
(2012)
Cancer Res
, vol.72
, pp. 1853-1864
-
-
Ning, N.1
-
49
-
-
77956428880
-
Therapeutic cell engineering with surface-conjugated synthetic nanoparticles
-
Stephan, M. T., Moon, J. J., Um, S. H., Bershteyn, A. & Irvine, D. J. Therapeutic cell engineering with surface-conjugated synthetic nanoparticles. Nat. Med. 16, 1035-1041 (2010).
-
(2010)
Nat. Med
, vol.16
, pp. 1035-1041
-
-
Stephan, M.T.1
Moon, J.J.2
Um, S.H.3
Bershteyn, A.4
Irvine, D.J.5
-
50
-
-
0037367965
-
T-cell epitope mapping using the ELISPOT approach
-
Anthony, D. D. & Lehmann, P. V. T-cell epitope mapping using the ELISPOT approach. Methods 29, 260-269 (2003).
-
(2003)
Methods
, vol.29
, pp. 260-269
-
-
Anthony, D.D.1
Lehmann, P.V.2
|