Colocalized delivery of adjuvant and antigen using nanolipoprotein particles enhances the immune response to recombinant antigens

Journal of the American Chemical Society

Volumn 135, Issue 6, 2013, Pages 2044-2047

  Fischer, Nicholas O ^a   Rasley, Amy ^a   Corzett, Michele ^a   Hwang, Mona H ^a   Hoeprich, Paul D ^a   Blanchette, Craig D ^a  

^a LAWRENCE LIVERMORE NATIONAL LABORATORY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMPHIPATHIC; ANTIBODY PRODUCTION; ANTIBODY TITERS; CO DELIVERIES; COLOCALIZATION; CPG OLIGODEOXYNUCLEOTIDES; HIS-TAGGED PROTEINS; IMMUNE RESPONSE; IMMUNE STIMULATION; IMMUNOGENICITY; LIPID A; VACCINE DELIVERY; YERSINIA PESTIS;

ANTIBODIES; MAMMALS; VACCINES;

ANTIGENS;

ADJUVANT; CPG OLIGODEOXYNUCLEOTIDE; HEMAGGLUTININ; IMMUNOGLOBULIN G; INFLUENZA VACCINE; LIPID A; NANOPARTICLE; NICKEL CHELATING NANOLIPOPROTEIN PARTICLE; POLYHISTIDINE TAG; RECOMBINANT ANTIGEN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANTIBODY PRODUCTION; ANTIBODY TITER; ARTICLE; CHEMICAL MODIFICATION; DRUG DELIVERY SYSTEM; DRUG FORMULATION; IMMUNE RESPONSE; MOUSE; NONHUMAN; PROTEIN BINDING; PROTEIN LOCALIZATION; VACCINATION; YERSINIA PESTIS;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; ANTIGENS, BACTERIAL; HEMAGGLUTININ GLYCOPROTEINS, INFLUENZA VIRUS; LIPOPROTEINS; MICE; NANOPARTICLES; NICKEL; PORE FORMING CYTOTOXIC PROTEINS; RECOMBINANT PROTEINS; VACCINES;

EID: 84873616727     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja3063293     Document Type: Article

References (18)

1. Aguilar, J. C.; Rodriguez, E. G. Vaccine 2007, 25, 3752
2. Mata-Haro, V.; Cekic, C.; Martin, M.; Chilton, P. M.; Casella, C. R.; Mitchell, T. C. Science 2007, 316, 1628
3. Krieg, A. M. Curr. Opin. Immunol. 2000, 12, 35
4. Diwan, M.; Elamanchili, P.; Cao, M.; Samuel, J. Curr. Drug Delivery 2004, 1, 405
5. Zhang, X. Q.; Dahle, C. E.; Baman, N. K.; Rich, N.; Weiner, G. J.; Salem, A. K. J. Immunother. 2007, 30, 469
6. Badiee, A.; Jaafari, M. R.; Samiei, A.; Soroush, D.; Khamesipour, A. Clin. Vaccine Immunol. 2008, 15, 668
7. Blanchette, C. D.; Segelke, B. W.; Fischer, N.; Corzett, M. H.; Kuhn, E. A.; Cappuccio, J. A.; Benner, W. H.; Coleman, M. A.; Chromy, B. A.; Bench, G.; Hoeprich, P. D.; Sulchek, T. A. Int. J. Mol. Sci. 2009, 10, 2958
8. Fischer, N. O.; Blanchette, C. D.; Segelke, B. W.; Corzett, M.; Chromy, B. A.; Kuhn, E. A.; Bench, G.; Hoeprich, P. D. Plos One 2010, 5 e11643
9. Blanchette, C. D.; Law, R.; Benner, W. H.; Pesavento, J. B.; Cappuccio, J. A.; Walsworth, V.; Kuhn, E. A.; Corzett, M.; Chromy, B. A.; Segelke, B. W.; Coleman, M. A.; Bench, G.; Hoeprich, P. D.; Sulchek, T. A. J. Lipid Res. 2008, 49, 1420
10. Ryan, R. O. Expert Opin. Drug Delivery 2008, 5, 343
11. Cormode, D. P.; Chandrasekar, R.; Delshad, A.; Briley-Saebo, K. C.; Calcagno, C.; Barazza, A.; Mulder, W. J. M.; Fisher, E. A.; Fayad, Z. A. Bioconjugate Chem. 2009, 20, 937
12. Fischer, N. O.; Infante, E.; Ishikawa, T.; Blanchette, C. D.; Bourne, N.; Hoeprich, P. D.; Mason, P. W. Bioconjugate Chem. 2010, 21, 1018
13. Bhattacharya, P.; Grimme, S.; Ganesh, B.; Gopisetty, A.; Sheng, J. R.; Martinez, O.; Jayarama, S.; Artinger, M.; Meriggioli, M.; Prabhakar, B. S. J. Virol. 2010, 84, 361
14. Fischer, N. O.; Blanchette, C. D.; Chromy, B. A.; Kuhn, E. A.; Segelke, B. W.; Corzett, M.; Bench, G.; Mason, P. W.; Hoeprich, P. D. Bioconjugate Chem. 2009, 20, 460
15. Blanchette, C. D.; Fischer, N. O.; Corzett, M.; Bench, G.; Hoeprich, P. D. Bioconjugate Chem. 2010, 21, 1321
16. Cornelissen, L. A.; de Vries, R. P.; de Boer-Luijtze, E. A.; Rigter, A.; Rottier, P. J.; de Haan, C. A. Plos One 2010, 5 e10645
17. Davis, H. L.; Weeratna, R. D.; McCluskie, M. J.; Xu, Y. Vaccine 2000, 18, 1755
18. Anderson, G. W.; Leary, S. E. C.; Williamson, E. D.; Titball, R. W.; Welkos, S. L.; Worsham, P. L.; Friedlander, A. M. Infect. Immun. 1996, 64, 4580