Plumbagin suppresses the migration and invasion of glioma cells via downregulation of MMP-2/9 expression and inaction of PI3K/Akt signaling pathway in vitro

Journal of Pharmacological Sciences

Volumn 134, Issue 1, 2017, Pages 59-67

  Chen, Guanghui ^a   Yue, Yan ^a   Qin, Jun ^a   Xiao, Xinping ^a   Ren, Qing ^a   Xiao, Bin ^a  

^a HUBEI UNIVERSITY OF MEDICINE   (China)

Author keywords

Glioma; Invasion; Matrix metalloproteinase; Migration; Plumbagin

Indexed keywords

GELATINASE A; GELATINASE B; PHOSPHATIDYLINOSITOL 3 KINASE; PLUMBAGIN; PROTEIN KINASE B; TRANSCRIPTION FACTOR SP1; NAPHTHOQUINONE;

ANTIINVASION ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; ARTICLE; CELL INVASION; CELL MIGRATION; CONTROLLED STUDY; DOWN REGULATION; DRUG ACTIVITY; ENZYME ACTIVITY; ENZYME INHIBITION; GLIOMA; HUMAN; HUMAN CELL; IN VITRO STUDY; LIMIT OF QUANTITATION; SIGNAL TRANSDUCTION; APOPTOSIS; CELL MOTION; CELL PROLIFERATION; CELL SURVIVAL; DRUG EFFECTS; METABOLISM; TUMOR CELL LINE; TUMOR INVASION;

APOPTOSIS; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; CELL SURVIVAL; DOWN-REGULATION; GLIOMA; HUMANS; MATRIX METALLOPROTEINASE 2; MATRIX METALLOPROTEINASE 9; NAPHTHOQUINONES; NEOPLASM INVASIVENESS; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION;

EID: 85019057597     PISSN: 13478613     EISSN: 13478648     Source Type: Journal    
DOI: 10.1016/j.jphs.2017.04.003     Document Type: Article

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