메뉴 건너뛰기




Volumn 77, Issue 9, 2017, Pages 2266-2278

Cellular and molecular identity of tumor-associated macrophages in glioblastoma

Author keywords

[No Author keywords available]

Indexed keywords

CD45 ANTIGEN; CHEMOKINE RECEPTOR CCR2; CHEMOKINE RECEPTOR CX3CR1; MONOCYTE CHEMOTACTIC PROTEIN 1; CCR2 PROTEIN, MOUSE; CHEMOKINE RECEPTOR; CX3CR1 PROTEIN, MOUSE;

EID: 85019045212     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-16-2310     Document Type: Article
Times cited : (445)

References (46)
  • 3
    • 78650677818 scopus 로고    scopus 로고
    • Neurofibromatosis-1 heterozygosity increases microglia in a spatially and temporally restricted pattern relevant to mouse optic glioma formation and growth
    • Simmons GW, Pong WW, Emnett RJ, White CR, Gianino SM, Rodriguez FJ, et al. Neurofibromatosis-1 heterozygosity increases microglia in a spatially and temporally restricted pattern relevant to mouse optic glioma formation and growth. J Neuropathol Exp Neurol 2011;70:51-62.
    • (2011) J Neuropathol Exp Neurol , vol.70 , pp. 51-62
    • Simmons, G.W.1    Pong, W.W.2    Emnett, R.J.3    White, C.R.4    Gianino, S.M.5    Rodriguez, F.J.6
  • 4
    • 84963964175 scopus 로고    scopus 로고
    • RNA sequencing of tumor-associated microglia reveals Ccl5 as a stromal chemokine critical for neurofibromatosis-1 glioma growth
    • Solga AC, Pong WW, Kim KY, Cimino PJ, Toonen JA, Walker J, et al. RNA sequencing of tumor-associated microglia reveals Ccl5 as a stromal chemokine critical for neurofibromatosis-1 glioma growth. Neoplasia 2015;17:776-88.
    • (2015) Neoplasia , vol.17 , pp. 776-788
    • Solga, A.C.1    Pong, W.W.2    Kim, K.Y.3    Cimino, P.J.4    Toonen, J.A.5    Walker, J.6
  • 5
    • 84953747412 scopus 로고    scopus 로고
    • The role of microglia and macrophages in glioma maintenance and progression
    • Hambardzumyan D, Gutmann DH, Kettenmann H. The role of microglia and macrophages in glioma maintenance and progression. Nat Neurosci 2016;19:20-7.
    • (2016) Nat Neurosci , vol.19 , pp. 20-27
    • Hambardzumyan, D.1    Gutmann, D.H.2    Kettenmann, H.3
  • 7
    • 84966552295 scopus 로고    scopus 로고
    • Orally administered colony stimulating factor 1 receptor inhibitor PLX3397 in recurrent glioblastoma: An Ivy Foundation Early Phase Clinical Trials Consortium phase II study
    • Butowski N, Colman H, De Groot JF, Omuro AM, Nayak L, Wen PY, et al. Orally administered colony stimulating factor 1 receptor inhibitor PLX3397 in recurrent glioblastoma: an Ivy Foundation Early Phase Clinical Trials Consortium phase II study. Neuro Oncol 2016;18:557-64.
    • (2016) Neuro Oncol , vol.18 , pp. 557-564
    • Butowski, N.1    Colman, H.2    De Groot, J.F.3    Omuro, A.M.4    Nayak, L.5    Wen, P.Y.6
  • 8
    • 0034093158 scopus 로고    scopus 로고
    • Flow cytometric characterization of tumor-associated macrophages in experimental gliomas
    • Badie B, Schartner JM. Flow cytometric characterization of tumor-associated macrophages in experimental gliomas. Neurosurgery 2000;46: 957-61.
    • (2000) Neurosurgery , vol.46 , pp. 957-961
    • Badie, B.1    Schartner, J.M.2
  • 9
    • 84929258477 scopus 로고    scopus 로고
    • Resident microglia, and not peripheral macrophages, are the main source of brain tumor mononuclear cells
    • Muller A, Brandenburg S, Turkowski K, Muller S, Vajkoczy P. Resident microglia, and not peripheral macrophages, are the main source of brain tumor mononuclear cells. Int J Cancer 2015;137:278-88.
    • (2015) Int J Cancer , vol.137 , pp. 278-288
    • Muller, A.1    Brandenburg, S.2    Turkowski, K.3    Muller, S.4    Vajkoczy, P.5
  • 10
    • 63849335831 scopus 로고    scopus 로고
    • Flow cytometry and in vitro analysis of human glioma-associated macrophages. Laboratory investigation
    • Parney IF, Waldron JS, Parsa AT. Flow cytometry and in vitro analysis of human glioma-associated macrophages. Laboratory investigation. J Neurosurg 2009;110:572-82.
    • (2009) J Neurosurg , vol.110 , pp. 572-582
    • Parney, I.F.1    Waldron, J.S.2    Parsa, A.T.3
  • 11
    • 84957810905 scopus 로고    scopus 로고
    • Glioblastoma: Defining tumor niches
    • Hambardzumyan D, Bergers G. Glioblastoma: defining tumor niches. Trends Cancer 2015;1:252-65.
    • (2015) Trends Cancer , vol.1 , pp. 252-265
    • Hambardzumyan, D.1    Bergers, G.2
  • 12
    • 0037963473 scopus 로고    scopus 로고
    • Blood monocytes consist of two principal subsets with distinct migratory properties
    • Geissmann F, Jung S, Littman DR. Blood monocytes consist of two principal subsets with distinct migratory properties. Immunity 2003;19: 71-82.
    • (2003) Immunity , vol.19 , pp. 71-82
    • Geissmann, F.1    Jung, S.2    Littman, D.R.3
  • 13
    • 84872765982 scopus 로고    scopus 로고
    • Fate mapping reveals origins and dynamics of monocytes and tissue macrophages under homeostasis
    • Yona S, Kim KW, Wolf Y,Mildner A, Varol D, Breker M, et al. Fate mapping reveals origins and dynamics of monocytes and tissue macrophages under homeostasis. Immunity 2013;38:79-91.
    • (2013) Immunity , vol.38 , pp. 79-91
    • Yona, S.1    Kim, K.W.2    Wolf, Y.3    Mildner, A.4    Varol, D.5    Breker, M.6
  • 15
    • 0034028817 scopus 로고    scopus 로고
    • Analysis of fractalkine receptor CX(3)CR1 function by targeted deletion and green fluorescent protein reporter gene insertion
    • Jung S, Aliberti J, Graemmel P, Sunshine MJ, Kreutzberg GW, Sher A, et al. Analysis of fractalkine receptor CX(3)CR1 function by targeted deletion and green fluorescent protein reporter gene insertion. Mol Cell Biol 2000;20:4106-14.
    • (2000) Mol Cell Biol , vol.20 , pp. 4106-4114
    • Jung, S.1    Aliberti, J.2    Graemmel, P.3    Sunshine, M.J.4    Kreutzberg, G.W.5    Sher, A.6
  • 18
    • 0032536531 scopus 로고    scopus 로고
    • Abnormalities in monocyte recruitment and cytokine expression in monocyte chemoattractant protein 1-deficient mice
    • Lu B, Rutledge BJ, Gu L, Fiorillo J, Lukacs NW, Kunkel SL, et al. Abnormalities in monocyte recruitment and cytokine expression in monocyte chemoattractant protein 1-deficient mice. J Exp Med 1998;187:601-8.
    • (1998) J Exp Med , vol.187 , pp. 601-608
    • Lu, B.1    Rutledge, B.J.2    Gu, L.3    Fiorillo, J.4    Lukacs, N.W.5    Kunkel, S.L.6
  • 19
    • 84919455244 scopus 로고    scopus 로고
    • Microglial displacement of inhibitory synapses provides neuroprotection in the adult brain
    • Chen Z, Jalabi W, Hu W, Park HJ, Gale JT, Kidd GJ, et al. Microglial displacement of inhibitory synapses provides neuroprotection in the adult brain. Nat Commun 2014;5:4486.
    • (2014) Nat Commun , vol.5 , pp. 4486
    • Chen, Z.1    Jalabi, W.2    Hu, W.3    Park, H.J.4    Gale, J.T.5    Kidd, G.J.6
  • 20
    • 77952310528 scopus 로고    scopus 로고
    • A human functional protein interaction network and its application to cancer data analysis
    • WuG, Feng X, Stein L. A human functional protein interaction network and its application to cancer data analysis. Genome Biol 2010;11:R53.
    • (2010) Genome Biol , vol.11 , pp. R53
    • Wu, G.1    Feng, X.2    Stein, L.3
  • 21
    • 79551587720 scopus 로고    scopus 로고
    • Cytoscape 2.8: New features for data integration and network visualization
    • Smoot ME, Ono K, Ruscheinski J, Wang PL, Ideker T. Cytoscape 2.8: new features for data integration and network visualization. Bioinformatics 2011;27:431-2.
    • (2011) Bioinformatics , vol.27 , pp. 431-432
    • Smoot, M.E.1    Ono, K.2    Ruscheinski, J.3    Wang, P.L.4    Ideker, T.5
  • 22
    • 36448955070 scopus 로고    scopus 로고
    • Microglia in the adult brain arise from Ly-6ChiCCR2+ monocytes only under defined host conditions
    • Mildner A, Schmidt H, Nitsche M, Merkler D, Hanisch UK, Mack M, et al. Microglia in the adult brain arise from Ly-6ChiCCR2+ monocytes only under defined host conditions. Nat Neurosci 2007;10:1544-53.
    • (2007) Nat Neurosci , vol.10 , pp. 1544-1553
    • Mildner, A.1    Schmidt, H.2    Nitsche, M.3    Merkler, D.4    Hanisch, U.K.5    Mack, M.6
  • 24
    • 84928254123 scopus 로고    scopus 로고
    • A dynamic spectrum of monocytes arising from the in situ reprogramming of CCR2+ monocytes at a site of sterile injury
    • Dal-Secco D, Wang J, Zeng Z, Kolaczkowska E, Wong CH, Petri B, et al. A dynamic spectrum of monocytes arising from the in situ reprogramming of CCR2+ monocytes at a site of sterile injury. J Exp Med 2015;212:447-56.
    • (2015) J Exp Med , vol.212 , pp. 447-456
    • Dal-Secco, D.1    Wang, J.2    Zeng, Z.3    Kolaczkowska, E.4    Wong, C.H.5    Petri, B.6
  • 25
    • 84855384345 scopus 로고    scopus 로고
    • The fractalkine receptor but not CCR2 is present on microglia from embryonic development throughout adulthood
    • Mizutani M, Pino PA, Saederup N, Charo IF, Ransohoff RM, Cardona AE. The fractalkine receptor but not CCR2 is present on microglia from embryonic development throughout adulthood. J Immunol 2012;188: 29-36.
    • (2012) J Immunol , vol.188 , pp. 29-36
    • Mizutani, M.1    Pino, P.A.2    Saederup, N.3    Charo, I.F.4    Ransohoff, R.M.5    Cardona, A.E.6
  • 26
    • 0014851851 scopus 로고
    • Studies on the chemotherapy of experimental brain tumors: Development of an experimental model
    • Ausman JI, Shapiro WR, Rall DP. Studies on the chemotherapy of experimental brain tumors: development of an experimental model. Cancer Res 1970;30:2394-400.
    • (1970) Cancer Res , vol.30 , pp. 2394-2400
    • Ausman, J.I.1    Shapiro, W.R.2    Rall, D.P.3
  • 27
    • 84934300728 scopus 로고    scopus 로고
    • Loss of CX3CR1 increases accumulation of inflammatory monocytes and promotes gliomagenesis
    • Feng X, Szulzewsky F, Yerevanian A, Chen Z, Heinzmann D, Rasmussen RD, et al. Loss of CX3CR1 increases accumulation of inflammatory monocytes and promotes gliomagenesis. Oncotarget 2015;6:15077-94.
    • (2015) Oncotarget , vol.6 , pp. 15077-15094
    • Feng, X.1    Szulzewsky, F.2    Yerevanian, A.3    Chen, Z.4    Heinzmann, D.5    Rasmussen, R.D.6
  • 29
    • 78149360132 scopus 로고    scopus 로고
    • Fate mapping analysis reveals that adultmicroglia derive from primitive macrophages
    • Ginhoux F, Greter M, Leboeuf M, Nandi S, See P, Gokhan S, et al. Fate mapping analysis reveals that adultmicroglia derive from primitive macrophages. Science 2010;330:841-5.
    • (2010) Science , vol.330 , pp. 841-845
    • Ginhoux, F.1    Greter, M.2    Leboeuf, M.3    Nandi, S.4    See, P.5    Gokhan, S.6
  • 31
    • 0030809822 scopus 로고    scopus 로고
    • Impaired monocyte migration and reduced type 1 (Th1) cytokine responses in C-C chemokine receptor 2 knockout mice
    • Boring L, Gosling J, Chensue SW, Kunkel SL, Farese RVJr, Broxmeyer HE, et al. Impaired monocyte migration and reduced type 1 (Th1) cytokine responses in C-C chemokine receptor 2 knockout mice. J Clin Invest 1997;100:2552-61.
    • (1997) J Clin Invest , vol.100 , pp. 2552-2561
    • Boring, L.1    Gosling, J.2    Chensue, S.W.3    Kunkel, S.L.4    Farese, R.V.5    Broxmeyer, H.E.6
  • 33
    • 80052246111 scopus 로고    scopus 로고
    • Infiltrating monocytes trigger EAE progression, but do not contribute to the resident microglia pool
    • Ajami B, Bennett JL, Krieger C, McNagny KM, Rossi FM. Infiltrating monocytes trigger EAE progression, but do not contribute to the resident microglia pool. Nat Neurosci 2011;14:1142-9.
    • (2011) Nat Neurosci , vol.14 , pp. 1142-1149
    • Ajami, B.1    Bennett, J.L.2    Krieger, C.3    McNagny, K.M.4    Rossi, F.M.5
  • 34
    • 84945470816 scopus 로고    scopus 로고
    • Differential roles of resident microglia and infiltrating monocytes in murine CNS autoimmunity
    • Shemer A, Jung S. Differential roles of resident microglia and infiltrating monocytes in murine CNS autoimmunity. Semin Immunopathol 2015; 37:613-23.
    • (2015) Semin Immunopathol , vol.37 , pp. 613-623
    • Shemer, A.1    Jung, S.2
  • 35
    • 36448994709 scopus 로고    scopus 로고
    • Local self-renewal can sustain CNS microglia maintenance and function throughout adult life
    • Ajami B, Bennett JL, Krieger C, Tetzlaff W, Rossi FM. Local self-renewal can sustain CNS microglia maintenance and function throughout adult life. Nat Neurosci 2007;10:1538-43.
    • (2007) Nat Neurosci , vol.10 , pp. 1538-1543
    • Ajami, B.1    Bennett, J.L.2    Krieger, C.3    Tetzlaff, W.4    Rossi, F.M.5
  • 36
    • 84898676953 scopus 로고    scopus 로고
    • Colony-stimulating factor 1 receptor signaling is necessary for microglia viability, unmasking a microglia progenitor cell in the adult brain
    • Elmore MR, Najafi AR, Koike MA, Dagher NN, Spangenberg EE, Rice RA, et al. Colony-stimulating factor 1 receptor signaling is necessary for microglia viability, unmasking a microglia progenitor cell in the adult brain. Neuron 2014;82:380-97.
    • (2014) Neuron , vol.82 , pp. 380-397
    • Elmore, M.R.1    Najafi, A.R.2    Koike, M.A.3    Dagher, N.N.4    Spangenberg, E.E.5    Rice, R.A.6
  • 37
    • 80355146868 scopus 로고    scopus 로고
    • Monocyte recruitment during infection and inflammation
    • Shi C, Pamer EG. Monocyte recruitment during infection and inflammation. Nat Rev Immunol 2011;11:762-74.
    • (2011) Nat Rev Immunol , vol.11 , pp. 762-774
    • Shi, C.1    Pamer, E.G.2
  • 38
    • 84923068676 scopus 로고    scopus 로고
    • Periostin secreted by glioblastoma stem cells recruits M2 tumour-associated macrophages and promotes malignant growth
    • Zhou W, Ke SQ, Huang Z, Flavahan W, Fang X, Paul J, et al. Periostin secreted by glioblastoma stem cells recruits M2 tumour-associated macrophages and promotes malignant growth. Nat Cell Biol 2015;17:170-82.
    • (2015) Nat Cell Biol , vol.17 , pp. 170-182
    • Zhou, W.1    Ke, S.Q.2    Huang, Z.3    Flavahan, W.4    Fang, X.5    Paul, J.6
  • 41
    • 28544446111 scopus 로고    scopus 로고
    • Monocyte and macrophage heterogeneity
    • Gordon S, Taylor PR. Monocyte and macrophage heterogeneity. Nat Rev Immunol 2005;5:953-64.
    • (2005) Nat Rev Immunol , vol.5 , pp. 953-964
    • Gordon, S.1    Taylor, P.R.2
  • 43
    • 80052746486 scopus 로고    scopus 로고
    • Systemic delivery of neutralizing antibody targeting CCL2 for glioma therapy
    • Zhu X, Fujita M, Snyder LA, Okada H. Systemic delivery of neutralizing antibody targeting CCL2 for glioma therapy. J Neurooncol 2011;104: 83-92.
    • (2011) J Neurooncol , vol.104 , pp. 83-92
    • Zhu, X.1    Fujita, M.2    Snyder, L.A.3    Okada, H.4
  • 44
    • 84989941652 scopus 로고    scopus 로고
    • CCL2 produced by the glioma microenvironment is essential for the recruitment of regulatory T cells and myeloid-derived suppressor cells
    • Chang AL, Miska J, Wainwright DA, Dey M, Rivetta CV, Yu D, et al. CCL2 produced by the glioma microenvironment is essential for the recruitment of regulatory T cells and myeloid-derived suppressor cells. Cancer Res 2016;76:5671-82.
    • (2016) Cancer Res , vol.76 , pp. 5671-5682
    • Chang, A.L.1    Miska, J.2    Wainwright, D.A.3    Dey, M.4    Rivetta, C.V.5    Yu, D.6
  • 46
    • 34147164049 scopus 로고    scopus 로고
    • Critical roles for CCR2 and MCP-3 in monocyte mobilization from bone marrow and recruitment to inflammatory sites
    • Tsou CL, Peters W, Si Y, Slaymaker S, Aslanian AM, Weisberg SP, et al. Critical roles for CCR2 and MCP-3 in monocyte mobilization from bone marrow and recruitment to inflammatory sites. J Clin Invest 2007; 117:902-9.
    • (2007) J Clin Invest , vol.117 , pp. 902-909
    • Tsou, C.L.1    Peters, W.2    Si, Y.3    Slaymaker, S.4    Aslanian, A.M.5    Weisberg, S.P.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.